ライフサイエンスコーパス: intermediate filament protein

1 e intermediate filament protein vimentin, an intermediate filament protein.

2 ates expression of nestin, an embryonic cell intermediate filament protein.

3 ween the eye lens proteins and the ancestral intermediate filament protein.

4 is the gene that encodes the major astrocyte intermediate filament protein.

5 treatments with serotonin, appeared to be an intermediate filament protein.

6 t function shared by K6, other keratins, and intermediate filament proteins.

7 nuclear organization, such as lamin nuclear intermediate filament proteins.

8 y provide a novel nonmechanical function for intermediate filament proteins.

9 e up the type I (K9-K20) and type II (K1-K8) intermediate filament proteins.

10 ined heptad repeat domains characteristic of intermediate filament proteins.

11 rminal domain, all common features of type 6 intermediate filament proteins.

12 keratins 8 (K8) and 18 (K18) as their major intermediate filament proteins.

13 otic cytoskeleton belonging to the family of intermediate filament proteins.

14 s and probably the most abundant of neuronal intermediate filament proteins.

15 keratins 8 (K8) and 18 (K18) as their major intermediate filament proteins.

16 all three tektin polypeptides is similar to intermediate filament proteins.

17 nd keratin 18 (K18), two epithelial-specific intermediate filament proteins.

18 vement of the auxiliary beta subunit through intermediate filament proteins.

19 (K8/18) are simple epithelial cell-specific intermediate filament proteins.

20 ions at late times, containing predominantly intermediate filament proteins.

21 The results suggest that an intermediate filament protein acts in a novel pathway to

22 Other neuronal intermediate filament proteins (alpha-internexin, periph

23 Tax-binding protein as the neuronal specific intermediate filament protein, alpha-internexin.

24 patterns and function of internexin neuronal intermediate filament protein-alpha a (inaa), the encodi

25 nvestigate the roles of vimentin, a type III intermediate filament protein and a marker of epithelial

26 eased abundances of extracellular matrix and intermediate filament proteins and decreased abundances

27 a previously unsuspected association between intermediate filament proteins and the adaptor complex A

28 Intermediate filament proteins and the ECM have key role

29 ffer to those found both in the invertebrate intermediate filament proteins and the vertebrate lamins

30 Experiments with pan-specific antibodies to intermediate filament proteins and to cytokeratins sugge

31 ted the LNDR to LNDS in vimentin, a Type III intermediate filament protein, and have examined the imp

32 ures, (2) a comparison of their structure to intermediate filament proteins, and (3) their possible o

33 onnexins, growth factors, membrane proteins, intermediate filament proteins, and chaperones.

34 ined heptad repeat domains characteristic of intermediate filament proteins, and several of the mutat

35 ed its interactions with 14-3-3 and vimentin intermediate filament proteins, and vimentin depletion i

36 tive cancer cells, suggesting that these two intermediate filament proteins are necessary for fulvest

37 ich the type VI nestin and type III vimentin intermediate filament proteins are replaced by a series

38 defg) found in the alpha-helical sections of intermediate-filament proteins are hydrophobic, and the

39 Lamins, the type V nuclear intermediate filament proteins, are reported to function

40 eved to be a characteristic of the ancestral intermediate filament protein as it is found in many inv

41 PC1 proteins included keratin intermediate filaments; proteins associated with inflamm

42 protein as it is found in many invertebrate intermediate filament proteins but has been lost from al

43 mbiguous assignment to any existing class of intermediate filament protein, but exhibits a gene struc

44 unterparts of eukaryotic actin, tubulin, and intermediate filament proteins, but they also have cytos

45 Lengsin and lens intermediate filament proteins co-localize at the plasma

46 AP-3 and intermediate filament proteins cosedimented and coimmuno

47 Importantly, dL5 fusions to an intermediate filament protein CreS are significantly les

48 urvature in a manner similar to deleting the intermediate filament protein crescentin, but it does no

49 Lamin A is a nuclear intermediate filament protein critical for nuclear archi

50 In particular, lamin A/C, an intermediate filament protein critical for the interphas

51 Desmin is a muscle-specific intermediate filament protein crucial for maintaining ca

52 ntified a novel association of AIRE with the intermediate filament protein cytokeratin 17 (K17) in th

53 ain subpopulations of cells that express the intermediate filament protein cytokeratin 5 (CK5).

54 ile, TGF-beta1 induced the expression of the intermediate filament protein desmin and interstitial ma

55 Here we describe the muscle-specific intermediate filament protein desmin as a novel caspase

56 Mice lacking the intermediate filament protein desmin demonstrate abnorma

57 The intermediate filament protein desmin is encoded by the g

58 ticular, we show that S-nitrosylation of the intermediate filament protein desmin is significantly in

59 Mutations in the DES gene coding for the intermediate filament protein desmin may cause skeletal

60 rdiomyopathy-associated gene DES encodes the intermediate filament protein desmin, which is important

61 eased in the cardiac tissue, whereas another intermediate filament protein, desmin, was reduced.

62 easured being loss of immunostaining for the intermediate filament protein, desmin.

63 or as a chaperone for the reorganization of intermediate filament proteins during terminal different

64 The A-type lamins, nuclear intermediate filament proteins encoded by the LMNA gene,

65 oteins but has been lost from all vertebrate intermediate filament proteins except the nuclear lamins

66 nt sedimentation (VGS) indicate that soluble intermediate filament protein exists as an approximately

67 terphase cell, approximately 5% of the total intermediate filament protein exists in a soluble form.

68 been well characterized as an intracellular intermediate filament protein expressed broadly in mesen

69 ive cells was also positive for vimentin, an intermediate filament protein expressed by mesenchymal c

70 d by alteration of the repertoire of keratin intermediate filament proteins expressed within neoplast

71 Vimentin, a member of the intermediate filament protein family, is regulated both

72 The lens fiber cell-specific intermediate filament protein filensin is essential for

73 purified proteins revealed the lens-specific intermediate filament proteins filensin and CP49.

74 at betaH-spectrin regulates the placement of intermediate filament proteins forming a terminal web ar

75 Mutations in intermediate filament protein genes are responsible for

76 ic inclusions in astrocytes that contain the intermediate filament protein GFAP in association with s

77 Although there was loss of expression of the intermediate filament proteins GFAP and vimentin, the ex

78 ITPKB (upregulated), the astrocyte specific intermediate filament protein, GFAP (upregulated), and t

79 der resulting from missense mutations of the intermediate filament protein, GFAP.

80 aused by mutations in the astrocyte-specific intermediate filament protein glial fibrillary acidic pr

81 function mutations in the gene coding for an intermediate filament protein glial fibrillary acidic pr

82 cells as determined by the expression of the intermediate filament proteins glial fibrillary acidic p

83 Insights into the role of the astrocyte intermediate filament protein, glial fibrillary acidic p

84 s in GFAP, which encodes the major astrocyte intermediate filament protein, glial fibrillary acidic p

85 The accumulation of the intermediate filament protein, glial fibrillary acidic p

86 ilated cardiomyopathy and indicate that this intermediate filament protein has an important role in c

87 Several hair-specific keratin intermediate filament proteins have been characterized,

88 Intermediate filament proteins have been reported to be

89 is unknown.SIGNIFICANCE STATEMENT Nestin, an intermediate filament protein highly expressed in neural

90 We found that in C. elegans touch neurons intermediate filament proteins IFD-1 and IFD-2 associate

91 bules and microfilaments, but its effects on intermediate filament proteins (IFs) are unknown.

92 In addition, an increase in intermediate filament protein immunoreactivity (vimentin

93 Alpha-internexin, a neuronal intermediate filament protein implicated in neurodegener

94 Peripherin, a neuronal intermediate filament protein implicated in neurodegener

95 Simple-type epithelial keratins are intermediate filament proteins important for mechanical

96 nthesis may contribute to its function as an intermediate filament protein in radial glia.

97 Desmin is an intermediate filament protein in skeletal muscle that fo

98 understanding the role of Akt signaling and intermediate filament proteins in autophagy and cancer.

99 embly dynamics of neurofilament and vimentin intermediate filament proteins in cultured cells using c

100 lates the more than 20 keratin type I and II intermediate filament proteins in epithelial cells.

101 The changes in the expression levels of intermediate filament proteins in response to these trea

102 carboxyl-terminal ends of the rod domains of intermediate filament proteins in reverse transcriptase-

103 the E1B 19K protein is found associated with intermediate filament proteins in the cytoplasm and the

104 in 8 (K8) and keratin-18 (K18) are the major intermediate filament proteins in the intestinal epithel

105 In contrast, the roles of intermediate filament proteins in this process are poorl

106 Mutations in lamins A and C, nuclear intermediate-filament proteins in nearly all somatic cel

107 ns of the expression of vimentin, a type III intermediate filament protein, in alveolar epithelial ce

108 consisting of phosphorylated 14-3-3 binding intermediate filament proteins, including keratins, coup

109 from the brush border, and redistribution of intermediate filament proteins into the brush border.

110 Desmin, the muscle-specific intermediate filament protein is one of the earliest kno

111 at aberrant hyperphosphorylation of neuronal intermediate filament proteins is involved in AD.

112 The expression of intermediate filament proteins is remarkably tissue spec

113 The expression of vimentin, a type-III intermediate filament protein, is a hallmark of the epit

114 Peripherin, another intermediate filament protein, is almost exclusively exp

115 Vimentin, an intermediate filament protein, is an M phase substrate f

116 6 (KRT16 in human, Krt16 in mouse), a type I intermediate filament protein, is constitutively express

117 peripherin gene, encoding a neuron-specific intermediate filament protein, is transcriptionally indu

118 Nestin, an intermediate filament protein, is widely used as stem ce

119 eriplakin (PPL), interacts specifically with intermediate filament proteins K8, K18, and vimentin via

120 The intermediate filament protein keratin 14 (K14) provides

121 High levels of the intermediate filament protein keratin 17 (K17) are assoc

122 Expression of the intermediate filament protein keratin 17 (K17) is robust

123 The intermediate filament protein keratin 17 (Krt17) shows h

124 of the 14-3-3 protein family bind the human intermediate filament protein keratin 18 (K18) in vivo,

125 The intermediate filament protein keratin 8 (K8) and its cro

126 The intermediate filament protein keratin 8 (K8) is critical

127 ut not wild-type podocin) complexes with the intermediate filament protein keratin 8 (K8) thereby pre

128 nse variant, p.Gly62Cys in KRT8 encoding the intermediate filament protein keratin 8.

129 between tTG and the breast-cancer marker and intermediate filament protein keratin-19.

130 Mutation of the cytoskeletal intermediate filament proteins keratin 8 and keratin 18

131 ility of the nucleus comes from meshworks of intermediate filament proteins known as lamins forming t

132 of the nuclear membrane is enriched with the intermediate filament protein lamin A.

133 We report that the intermediate filament protein lamin B, a component of th

134 The intermediate filament protein lamin B2 (LB2), normally a

135 in the LMNA gene, which encodes the nuclear intermediate filament proteins lamin A and C, two major

136 f glial fibrillary acidic protein (GFAP), an intermediate filament protein located within their cytop

137 c interaction of Tax and a neuronal specific intermediate filament protein may provide a clue to the

138 Cytokeratins, members of the family of intermediate filament proteins, may represent a new clas

139 transglutaminase-dependent reaction of this intermediate filament protein might influence the shape

140 4 residues in the otherwise highly conserved intermediate filament protein motif LNDR.

141 Among these is expression of the intermediate filament protein nestin and the brain fatty

142 We also have determined that the intermediate filament protein nestin correlates with tum

143 The intermediate filament protein Nestin identifies stem/pro

144 The intermediate filament protein Nestin labels populations

145 We found that the intermediate filament protein nestin physically interact

146 The intermediate filament protein Nestin serves as a biomark

147 These cells expressed the type VI intermediate filament protein nestin whose expression wa

148 IDE is known to bind the cytoplasmic intermediate filament protein nestin with high affinity.

149 to neurons and astrocytes, and expressed the intermediate filament protein nestin, a marker for proge

150 The intermediate filament protein, nestin, marks progenitor

151 Vimentin is an intermediate filament protein normally expressed in cell

152 ibrillary acidic protein (GFAP) is the major intermediate filament protein of astrocytes in the verte

153 pinal fluid that is specific for a cytosolic intermediate filament protein of astrocytes.

154 ere we examine the role of desmin, the major intermediate filament protein of muscle in organizing co

155 in keratin 8 (K8) and keratin 18 (K18), the intermediate filament proteins of hepatocytes, predispos

156 that 4.1R interacts with the characteristic intermediate filament proteins of postsynaptic densities

157 polypeptides 8 and 18 (K8/18) are the major intermediate filament proteins of simple-type epithelia.

158 How alterations in A-type lamins, intermediate filament proteins of the nuclear envelope e

159 Keratins 8 and 18 (K8/K18) are the intermediate filaments proteins of simple-type digestive

160 ysfunctional mutations in desmin, a type III intermediate filament protein, or alphaB-crystallin, a c

161 They also show that NF-M can partner with intermediate filament proteins other than the NF-H and N

162 Type III intermediate filament protein peripherin expression is a

163 Aberrant induction of expression of the intermediate filament protein peripherin, which is assoc

164 e Abs directed against the neuronal type III intermediate filament protein peripherin.

165 rker doublecortin and of the neuron-specific intermediate filament protein, peripherin, and by RA-sti

166 A- and alphaB-crystallins, the lens-specific intermediate filament proteins phakinin (CP49) and filen

167 All intermediate filament proteins possess three distinct do

168 Keratin 8 (K8) is a major intermediate filament protein present in enterocytes and

169 Vimentin, an abundant intermediate filament protein, presumably has an importa

170 Keratins are cytoplasmic intermediate filament proteins providing crucial structu

171 Here we show that keratin 17, an intermediate filament protein rapidly induced in wounded

172 clusion formation might extend to nonkeratin intermediate filament protein-related diseases.

173 We deleted the genes encoding two intermediate filament proteins required for astrocyte ac

174 Krt20 is an intermediate filament protein responsible for the struct

175 st consistently is desmin, a muscle-specific intermediate-filament protein responsible for the struct

176 region of CP49 (BFSP2; phakinin), a related intermediate filament protein specific to the lens.

177 man medulloblastoma, including expression of intermediate filament proteins specific for neurons and

178 In addition, several intermediate filament proteins such as vimentin and anne

179 same or very similar sites in multiple other intermediate filament proteins, suggests that the proces

180 d that vimentin, a leucine zipper-containing intermediate filament protein, suppresses ATF4-dependent

181 The intermediate filament protein synemin is present in astr

182 Taken together, Nes-S is a new neuronal intermediate filament protein that exerts a cytoprotecti

183 Vimentin is a cytoskeletal intermediate filament protein that governs the form and

184 Desmin is a muscle-specific intermediate filament protein that has fundamental role

185 BioID to lamin-A (LaA), a well-characterized intermediate filament protein that is a constituent of t

186 Lamin B1 (LMNB1) is an intermediate filament protein that is an integral compon

187 Keratin 17 (K17) is a type I intermediate filament protein that is constitutively exp

188 Keratin polypeptide 19 (K19) is a type I intermediate filament protein that is expressed in strat

189 GFAP is an intermediate filament protein that is expressed predomin

190 ften initiate the expression of vimentin, an intermediate filament protein that polymerizes into netw

191 It is composed mainly of lamins, which are intermediate filament proteins that assemble into a fila

192 Lamins are intermediate filament proteins that assemble into a mesh

193 Lamins are intermediate filament proteins that form a scaffold, ter

194 A-type lamins are intermediate filament proteins that provide a scaffold f

195 ds hnRNP K, with that of peripherin, another intermediate filament protein, the RNA for which does no

196 he three major domains that characterize all intermediate filament proteins, the carboxyl-terminal ta

197 evelopment and function depend on the type V intermediate filament proteins, the lamins, which are ma

198 ast few years it has become evident that the intermediate filament proteins, the types A and B nuclea

199 ive slime of hagfishes contains thousands of intermediate filament protein threads that are manufactu

200 mutation in the gene for CP49 (phakinin), an intermediate filament protein thus far demonstrated only

201 P49 gene is the first vertebrate cytoplasmic intermediate filament protein to be described with an ex

202 two-hybrid assay, and identified desmin, an intermediate filament protein, to interact with SPEG and

203 Nestin is an intermediate filament protein, transiently and abundantl

204 mined the gene expression of two radial glia intermediate filament proteins, transitin and vimentin,

205 key cytoskeletal proteins, including several intermediate filament proteins, triggers the dramatic di

206 All three proteins have the basic intermediate filament protein tripartite structure, whic

207 anes, we identified by mass spectrometry the intermediate filament protein vimentin and the microtubu

208 ized GST-Raf-1 as bait, we have isolated the intermediate filament protein vimentin as a Raf-1-associ

209 iotin-labeled artemisinin, we identified the intermediate filament protein vimentin as an artemisinin

210 was paralleled by the redistribution of the intermediate filament protein vimentin as well as by the

211 se to perform superresolution imaging of the intermediate filament protein vimentin by stimulated emi

212 The intermediate filament protein vimentin is involved in th

213 tor for activated C kinase 1 (RACK1) and the intermediate filament protein vimentin that correlated w

214 tion is accompanied by redistribution of the intermediate filament protein vimentin to form a cage su

215 All cells expressed the intermediate filament protein vimentin, an intermediate

216 dine salvage pathway, is associated with the intermediate filament protein vimentin, in NIH 3T3 fibro

217 The intermediate filament protein vimentin, which has been p

218 Focusing on the intermediate filament protein vimentin, which is frequen

219 both for desmin and the structurally related intermediate filament protein vimentin.

220 3-3 with a 55-kDa protein, identified as the intermediate filament protein vimentin.

221 es not recognize Rac1 but rather detects the intermediate filament protein vimentin.

222 elastic behavior of in vitro networks of the intermediate filament protein vimentin.

223 een the head domain and rod domain 1A of the intermediate filament protein vimentin.

224 llular histone proteins H2A, H3, and H4; the intermediate filament protein vimentin; the major HSV-1

225 onin significantly differed from that of the intermediate filament proteins vimentin and desmin as we

226 (ALYEQEIR, EAEEEKKVEGAGEEQAAAK) and another intermediate filament protein, vimentin (FADLSEAANR).

227 invasiveness by directly phosphorylating an intermediate filament protein, vimentin, thereby inhibit

228 The intermediate filament protein, vimentin, was upregulated

229 d interaction between SspC and an eukaryotic intermediate filament protein was identified.

230 pping clones were identified that encoded an intermediate filament protein we subsequently named desm

231 nated alpha-tubulin associates strongly with intermediate filament proteins, we examined the contribu

232 or subdomains of murine vimentin, a Type III intermediate filament protein, were fused with either th

233 Vimentin is an intermediate filament protein whose 3'untranslated seque

234 Vimentin is an intermediate filament protein whose expression correlate

235 Keratin 9 (K9) is a type I intermediate filament protein whose expression is confin

236 Keratin 8 (K8) and keratin 18 (K18) are the intermediate filament proteins whose phosphorylation/tra

237 ibe the identification of vimentin (VIM), an intermediate filament protein widely expressed in cells

238 Nestin, an intermediate filament protein widely used as a marker of

239 Keratin polypeptide 20 (K20) is an intermediate filament protein with preferential expressi