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1 t stable fluxes, hence avoiding depletion of intermediate metabolites.
2 ealed the accumulation of medicarpin and its intermediate metabolites.
3 HCV RNA could not be restored by isoprenoid intermediate metabolites.
4 ic balances or inferred from the labeling of intermediate metabolites.
5 al inner mitochondrial wall transporters for intermediate metabolites.
6 eled carbon fractional enrichment values for intermediate metabolites.
7 ion stoichiometry to conserve or not deplete intermediate metabolites.
8 cesses to coordinate and optimize energy and intermediate metabolites.
9 plexes, and minimizing accumulation of toxic intermediate metabolites.
10 lism that would explain accumulation of such intermediate metabolites.
11 fically the replenishment of fuel stores and intermediate metabolites.
12 etion-reuptake recycling for 12-HETE and its intermediate metabolites.
13 ne followed by electron rearrangement giving intermediate metabolite 2,7-DAM, and then trapping this
14 e activation (IMA) architecture, in which an intermediate metabolite activates transcription of pathw
15 lar, we find that pathways controlled by the intermediate metabolite activation (IMA) architecture, i
16 CR signaling is coupled to the regulation of intermediate metabolites and how changes in metabolite f
18 gh-throughput mediation analysis to identify intermediate metabolites and pathways linking PM(2.5) to
19 aintaining a sufficiently large inventory of intermediate metabolites and processing units required f
20 a, which are organelles that provide energy, intermediate metabolites, and additional activities to s
22 uppresses CYP7A1, leading to accumulation of intermediate metabolites at the branch point of the meva
23 agate elsewhere into metabolic networks, and intermediate metabolites can be freely shared by differe
24 cluding the metallophore staphylopine (StP), intermediate metabolites citrate and acetoin, and multip
26 ophan metabolism in liver and brain returned intermediate metabolite concentrations in the physiologi
28 tlenecks in substrate flow, with build-up of intermediate metabolites consistent with oxidative stres
29 epresent increased production and buildup of intermediate metabolites driven by decreased carbon cycl
30 cating intracellular dThd to be an essential intermediate metabolite for the synthesis of thymine-der
31 revealed a novel function of the MVA pathway intermediate metabolite FPP as a danger signal via trans
32 sterol biosynthesis and the formation of the intermediate metabolites geranylgeranylpyrophosphate (GG
33 cycles of enzymes for interconversions among intermediate metabolites; (ii) a catabolic module, with
34 host epithelial cell hinges on squalene, an intermediate metabolite in the host cholesterol biosynth
35 ase of geranylgeranyl diphosphate (GGPP), an intermediate metabolite in the mevalonate pathway, is re
37 al analysis, we identified marked changes of intermediate metabolites in ACE-overexpressing macrophag
38 aling a much wider regulatory role for these intermediate metabolites in an integrated biosynthesis n
39 concerning fluctuations in the abundance of intermediate metabolites in various common motifs of the
40 vary in their ability to detoxify the active intermediate metabolite of AFB(1), AFB(1)-exo-8,9-epoxid
41 asma membrane are determined by an important intermediate metabolite of dietary fat and an enzyme sys
42 the level of 7-dehydrocholesterol (7-DHC)-an intermediate metabolite of distal cholesterol biosynthes
44 also found 3-hydroxykynurenine, a neurotoxic intermediate metabolite of tryptophan, was negatively co
45 llular Ca2+ stores and leading to release of intermediate metabolites of arachidonic acid metabolism.
46 e observed significant (p < 0.05) changes in intermediate metabolites of energy metabolism and fatty
47 ause inhibiting FAS leads to accumulation of intermediate metabolites of fatty acid biosynthesis, we
49 utomatically quantifies all isotopologues of intermediate metabolites of glycolysis, TCA cycle, amino
50 the SLC22A1 locus for serum acylcarnitines, intermediate metabolites of mitochondrial oxidation whos
51 erol levels, implicating a role for upstream intermediate metabolites of the cholesterol synthesis pa
53 in hepatocytes, raising the possibility that intermediate metabolites of very long-chain fatty acids
56 that can overburden the cell and accumulate intermediate metabolites, resulting in reduced product t
57 ons between PAH degradation network data and intermediate metabolite structures, gaining information
58 ongatus PCC 11802 shows higher levels of key intermediate metabolites suggesting that this strain mig
59 lation of acetyl-CoA to form malonyl-CoA, an intermediate metabolite that plays a pivotal role in the
60 nols interact with gut microbiota to produce intermediate metabolites that can regulate appetite whil
61 aldehydes and acids (FTUALs and FTUCAs) are intermediate metabolites that form from the biotransform
62 he biotransformation of FTOHs and PAPs yield intermediate metabolites that have been observed to cova
63 s controlled by a feedback mechanism between intermediate metabolites, the redox state of the plastid
64 CYP1A1 can also produce highly carcinogenic intermediate metabolites through oxidation of polycyclic
67 ery-duplicating constraint, namely, that all intermediate metabolites used in active reactions must b
68 However, an accumulation in R2 of undegraded intermediate metabolites (volatile fatty acids, ketones,
69 midazo[4,5,1-ij]quinolin-2(1H) -one [(R)-6], intermediate metabolites, where N-demethylation to the i
70 a able to degrade such a wide variability of intermediate metabolites while limiting other strains.
71 study was to assess the reactivity of these intermediate metabolites with a series of nucleophilic a