ライフサイエンスコーパス: intermediate stage

1 herosclerosis was allowed to progress to the intermediate stage.

2 indicating that they represent a pretumoral intermediate stage.

3 that osteoclastogenesis is blocked at a late-intermediate stage.

4 to the nonpolar core of the bilayer at this intermediate stage.

5 nase activity state at the Holliday junction intermediate stage.

6 und state than by raising temperature at the intermediate stage.

7 temperature was used to arrest fusion at an intermediate stage.

8 bels apoptotic cells only during a transient intermediate stage.

9 ff base deprotonation at the lumirhodopsin I intermediate stage.

10 ailed by trapping Env-receptor binding at an intermediate stage.

11 ed medications, companion diagnostics are an intermediate stage.

12 ation while the polymer was processed at the intermediate stage.

13 hat the latter can develop through a CD25(+) intermediate stage.

14 ave now reported on the neurobiology of this intermediate stage.

15 erates, and ribbon bunches, were observed as intermediate stages.

16 d peak exercise images, with and without the intermediate stages.

17 gh to detect occult liver injury at early or intermediate stages.

18 se mutants block in a coordinated fashion at intermediate stages.

19 to the processive elongation complex through intermediate stages.

20 h has hindered studying the role of critical intermediate stages.

21 from E to HE to IAC cells, with identifiable intermediate stages.

22 especially challenging to identify early or intermediate stages.

23 edback is mediated via a cascade of multiple intermediate stages.

24 urgery in those patients who did not undergo intermediate staging.

25 es between 0 and 1 and predicts patients in "intermediate" stages.

26 nvestigate these biomechanical events in the intermediate stage 21 to determine insights into this cr

27 5% and 92.1% (early stages, 79.7% and 93.3%; intermediate stages, 72.1% and 96.2%; advanced stages, 6

28 The findings suggested that an intermediate stage Abeta(1-42) fibrillar precursor is op

29 This intermediate stage acts as a site of developmental devia

30 nuclear apoptosis in vitro was blocked at an intermediate stage after collapse of the chromatin again

31 ical development at a heretofore undescribed intermediate stage, after the splitting of the preplate,

32 To evaluate the incidence of intermediate-stage age-related macular degeneration (AMD

33 ular vascular development progressed through intermediate stages akin to those involved in the embryo

34 The arrest of enzymatic reaction at the intermediate stage allowed us to determine that the cons

35 Intermediate-stage AMD (AREDS stage 3) was determined fr

36 In participants with intermediate-stage AMD at enrollment in the Longitudinal

37 have an increased age-adjusted prevalence of intermediate-stage AMD compared with that found in a non

38 ncreased race- and sex-adjusted incidence of intermediate-stage AMD compared with that found in an HI

39 Intermediate-stage AMD was determined from enrollment re

40 4-fold increased age-adjusted prevalence of intermediate-stage AMD.

41 no ocular opportunistic infections, 9.9% had intermediate-stage AMD.

42 Children and adolescents with intermediate-stage and advanced-stage classical Hodgkin

43 Intermediate stages are characterized by disproportionat

44 Second, despite this similarity, different intermediate stages are more or less populated in the fo

45 Transitions among the various intermediate stages are the subject of many studies but

46 In early- and intermediate-stage atherosclerotic lesions, ACE was dete

47 s the first-line treatment for patients with intermediate stage B hepatocellular carcinoma (HCC), com

48 CD73 induction appears to mark a metastable intermediate stage before acquisition of effector functi

49 stood which signals are essential during the intermediate stages before terminal differentiation.

50 The module is inserted at an intermediate stage between a higher pressure sample cyli

51 a single trophic level, is formulated as an intermediate stage between any two of three classical th

52 Mild cognitive impairment (MCI) is an intermediate stage between cognitively normal older adul

53 This intermediate stage between fully sensitive and fully res

54 Prediabetes is an intermediate stage between normal glycemia and diabetes

55 ted hazardous condition is the temporal gap (intermediate stage) between the identification of an adv

56 aters in the cytoplasmic regions of the late-intermediate stages by measuring the rate of water excha

57 om aortic endothelial cells (ECs) through an intermediate stage called hemogenic endothelium by a pro

58 This intermediate stage, called hemifusion, is a critical eve

59 are free of symptoms are considered to have intermediate-stage cancer and can benefit from chemoembo

60 ognosis; however, accurate classification of intermediate-stage cases is problematic.

61 ransition from anagen to telogen involves an intermediate stage, catagen, consisting of a swift, apop

62 how image-forming eyes may have evolved via intermediate stages contrasting only a light and a dark

63 s, at speeds of roughly 60 nm s(-1)) into an intermediate stage corresponding to canonical 400 nm axi

64 6 tumor suppressor genes, all being early to intermediate stage disease.

65 that is, chemoembolization for patients with intermediate-stage disease and sorafenib for patients wi

66 th early-stage NLPHL other than stage IA and intermediate-stage disease mostly receive combined-modal

67 ns were timed at earlier and later phases of intermediate-stage disease, and photoreceptor degenerati

68 tients who began receiving zidovudine during intermediate-stage disease, changing to either combinati

69 Among patients with intermediate-stage disease, survival was similar between

70 mptomatic noninvasive multinodular tumors in intermediate-stage disease.

71 the 2102 patients were in treatment group 2 (intermediate-stage disease; n=455) and treatment group 3

72 nes and primary macrophages when added at an intermediate stage downstream of Env-CD4-coreceptor enga

73 that inhibits human pre-mRNA splicing at an intermediate stage during conversion of pre-catalytic sp

74 k was to assess whether the incorporation of intermediate stages during supine bicycle exercise echoc

75 Analyses of each intermediate stage for CD34, CD117, and CD94 cell surfac

76 ent of cellular proteins in transcription of intermediate stage genes may regulate the transition bet

77 g frame, originally shown to be one of three intermediate-stage genes that together can transactivate

78 curative treatment is available for early-to-intermediate stage HCC, characterized by large and/or mu

79 ias, as well as a cohort restricted to early/intermediate stage HCC.

80 der) with histologically confirmed early- or intermediate-stage HCC and Child-Pugh class A or B cirrh

81 med other prognostic models in patients with intermediate-stage HCC receiving TACE.

82 e impact of dynamic changes in patients with intermediate-stage HCC undergoing TACE.

83 Intermediate-stage HCC was defined as Barcelona Clinic L

84 ith HCC treated with TACE, 166 patients with intermediate-stage HCC who met the eligibility criteria

85 eluting bead (DEB) TACE in participants with intermediate-stage HCC, extended to Eastern Cooperative

86 For intermediate-stage HCC, transarterial chemoembolization

87 For intermediate-stage HCC, transarterial chemoembolization

88 mbolization (TACE) is the main treatment for intermediate stage hepatocellular carcinoma (HCC) with B

89 E) is the standard of care for patients with intermediate stage hepatocellular carcinoma, while the m

90 Background Intermediate stage hepatocellular carcinomas (HCCs) are

91 eneity of liver function and tumor burden in intermediate-stage hepatocellular carcinoma (HCC) result

92 drugs is standard treatment for unresectable intermediate-stage hepatocellular carcinoma but achieves

93 fective in the initial treatment of early to intermediate stage HNSCC but less effective for locally

94 ages (HR = 1.24, 95% CI, 1.09-1.41), 13% for intermediate stage (HR = 1.13, 95% CI, 1.05-1.22), where

95 tients who begin receiving zidovudine during intermediate-stage human immunodeficiency virus (HIV) in

96 Ringvent provides a new type of intermediate-stage hydrothermal system where off-axis hy

97 Imaging during intermediate stages improved the sensitivity for detecti

98 ormation of the enzyme that may represent an intermediate stage in a proposed product ejection mechan

99 Together, these findings resolve a discrete intermediate stage in formation of the AIS that is regul

100 to nuclear-encoded preproteins trapped at an intermediate stage in import across the envelope.

101 At an intermediate stage in method development, 1 pg of glycol

102 ering on the NE is arrested or delayed at an intermediate stage in pam1.

103 phenotype, which we postulate represents an intermediate stage in pathogen-host adaptation.

104 data indicate that indomethacin inhibits an intermediate stage in PCT development after the arrival

105 This conformation may represent an important intermediate stage in PFO pore formation.

106 s in platelet maturation, (b) identify a new intermediate stage in platelet production, the preplatel

107 he cortex has not been degraded represent an intermediate stage in spore germination, which we term s

108 d Drosophila shibire(ts1) mutants to trap an intermediate stage in synaptic vesicle recycling, we hav

109 substrates and shown to be applicable as an intermediate stage in the construction of polyarylated h

110 Cardiac hypertrophy is an intermediate stage in the development of heart failure.

111 e results suggest that Cen8 may represent an intermediate stage in the evolution of centromeres from

112 hesis that surface skimming may have been an intermediate stage in the evolution of insect flight, wh

113 w form of parental care provides a plausible intermediate stage in the evolution of viviparity in cae

114 l-shaped proplatelets, a recently discovered intermediate stage in the final process of platelet prod

115 ulation of neuronal responses in area V4, an intermediate stage in the form-processing, ventral visua

116 ers of syntelic attachments, which can be an intermediate stage in the formation of merotelic kinetoc

117 the floccular complex of the cerebellum, an intermediate stage in the neural circuit for smooth-purs

118 Prediabetes, an intermediate stage in the pathogenesis of type 2 diabete

119 rea (pollination races) represent a probable intermediate stage in the process of allopatric speciati

120 histologic changes, and that BE is an early intermediate stage in the process of EAC.

121 level representations and that area 3b is an intermediate stage in the processes leading to these rep

122 We identify DPN as an intermediate stage in the step-wise progression from nev

123 e report that neurons in macaque area V4, an intermediate stage in the ventral (object-related) pathw

124 Gao et al. uncover an intermediate stage in this process when viral escape fro

125 These stripes represent an intermediate stage in visual hierarchy and serve a key r

126 ent to the promoter and PIC assembly; (2) an intermediate stage in which NF-E2 binding (LCR-independe

127 c Ca(2+) concentrations, and proceeds via an intermediate stage in which vesicles appear to be cluste

128 s transition to heterotrophy and the role of intermediate stages in maintaining CEF.

129 The lack of known intermediate stages in most of these mutualisms, however

130 Since these mutations appear at early or intermediate stages in multistep journeys to neoplasia,

131 Thus, intermediate stages in object extraction should not elim

132 Intermediate stages in telomere clustering including min

133 This study has resolved intermediate stages in the developmental transition from

134 sister taxa that have either no placentas or intermediate stages in the evolution of a placenta.

135 were present in both foot lesions, revealing intermediate stages in the evolution of a tissue culture

136 nied by sister taxa that either lack or have intermediate stages in the evolution of the trait, prese

137 , and avoids purification of the products at intermediate stages in the procedure.

138 To search for novel intermediate stages in the process of intracellular gene

139 ing meiosis, mutations that cause defects at intermediate stages in the recombination process confer

140 afferents, but undergo low-pass filtering at intermediate stages in the vestibulocollic reflex.

141 ells derive from bone marrow stem cells, the intermediate stages in their development remain unknown.

142 RK1 and ERK2 activation suggests one or more intermediate stages in this pathway.

143 Intermediate stages in this process were isolated for st

144 +/-), CD62L(+), CXCR3(+)), followed by three intermediate stages: intermediate T cells 1 (CD45RO(+),

145 ve been well characterized structurally, the intermediate stages involved in this remarkable transfor

146 fected host cell, we find that trophozoites (intermediate-stage iRBCs) tend to flip due to their bico

147 This intermediate stage is soon abandoned and is replaced (in

148 Patients with intermediate-stage LAHNC were treated with concomitant b

149 y transform the diffusive nucleation with an intermediate-stage liquid into a martensitic generation

150 mproved in the early stage for all doses and intermediate stage low and mid dose groups 6 months post

151 MAIT cell development in which noncommitted, intermediate-stage MAIT cells undergo a first round of p

152 cycle regulation and functional role for the intermediate stage marker Dlc1 in facilitating mammalian

153 The management of early to intermediate-stage MASH-HCC typically involves surgery a

154 The intermediate stage may go undetected, as it typically is

155 In contrast, NALP3 functionality in intermediate stage melanoma cells requires activation of

156 The intermediate stage most proximal to HE, which we term pr

157 patients with NLPHL (early stages, n = 251; intermediate stages, n = 76; advanced stages, n = 144) w

158 somites; centra do not form via a cartilage intermediate stage, nor do they contain osteoblasts.

159 ation and TCR downmodulation, followed by an intermediate stage of anergy and subsequent deletion.

160 ered in receptor.hsp90 heterocomplexes at an intermediate stage of assembly in reticulocyte lysate, a

161 locked assembly of Raf.hsp90 complexes at an intermediate stage of assembly where Raf is still bound

162 FlgM, is able to sense the completion of an intermediate stage of assembly, the basal body-hook (BBH

163 ed the remnants of a clinically undetectable intermediate stage of astrocytic neoplastic transformati

164 mulus repetition) attenuates the subsequent, intermediate stage of auditory processing (100-200 ms).

165 The synapse splitting hypothesis predicts an intermediate stage of branched spines with both heads sh

166 decreased thereafter, suggesting roles in an intermediate stage of chondrogenesis.

167 nase inhibitors trap proteinases at the acyl-intermediate stage of cleavage of the serpin as a protei

168 is less than 26 million years old and at an intermediate stage of degeneration.

169 placed the CD10(-)CD62L(hi) population at an intermediate stage of differentiation between HSCs and l

170 apidly from naive to cells at a perforin low intermediate stage of differentiation, later forming a s

171 autoreactive thymocytes at the CD4(+)CD8(lo) intermediate stage of differentiation.

172 ns and that loss of Gata2 arrests them at an intermediate stage of differentiation.

173 s were also found, potentially indicating an intermediate stage of differentiation.

174 dologic issues, including conditioning on an intermediate stage of disease and depletion of susceptib

175 5-hydroxymethylcytosine (5hmC) is an intermediate stage of DNA de-methylation.

176 his does not take into account the important intermediate stage of drug tolerance.

177 between allotetraploids can occur without an intermediate stage of genome diploidization or a further

178 h-pressure NMR spectroscopy could capture an intermediate stage of hBD6-FX interaction, exhibiting fe

179 ype (Wt) length viral transcripts during the intermediate stage of infection, indicating that the A18

180 Birds were therefore studied at an intermediate stage of learning, after substantial experi

181 Nonubiquitinated receptors delay CCPs at an intermediate stage of maturation, after clathrin lattice

182 was preferentially phosphorylated during an intermediate stage of maturation.

183 ntified phosphoprotein is associated with an intermediate stage of memory for one-trial conditioning

184 Da phosphoprotein (CSP24) associated with an intermediate stage of memory, distinct from short-term m

185 with distinct properties was detected at an intermediate stage of neuronal differentiation.

186 Contour integration is an important intermediate stage of object recognition, in which line

187 al glucose regulation (NGR) to T2D is via an intermediate stage of prediabetes, characterized by impa

188 participates with heat shock proteins at an intermediate stage of progesterone receptor assembly, an

189 which the proteinase is trapped at the acyl intermediate stage of proteolysis of the serpin as a sub

190 ntensity function for the rod response at an intermediate stage of recovery from the conditioning fla

191 ts are trapped in the primitive streak at an intermediate stage of the epithelial-mesenchymal transit

192 conformational change of dengue virus at an intermediate stage of the fusion process.

193 s interactions within the active site at the intermediate stage of the reaction, suggesting a role of

194 and the use of core-level excitations in the intermediate stage of the spectroscopic process, the RIX

195 hydrophobic interactions are important at an intermediate stage of the transposition reaction, after

196 ction, and specifically at the CD4(+)CD8(lo) intermediate stage of thymocyte differentiation, where i

197 ests that bipedalism was attained through an intermediate stage of tripedalism.

198 mulation or removing drusen in the early and intermediate stages of AMD prior to vision loss.

199 To identify genes expressed at intermediate stages of Bacillus subtilis sporulation, we

200 Indeed, intersectin functions in the intermediate stages of clathrin-coated vesicle assembly.

201 erapeutic effectiveness of ERRP on early and intermediate stages of colon cancer by examining regress

202 there is conflicting evidence regarding the intermediate stages of crystallisation, how they manifes

203 mediolateral, and rostrocaudal dimensions at intermediate stages of development (E6-E10).

204 and fungus-like structures characteristic of intermediate stages of development displayed by the wild

205 G does not require gene expression data from intermediate stages of development.

206 orespore becomes dependent on the channel at intermediate stages of development.

207 ate developmental stages and buffered during intermediate stages of development.

208 We propose that, at these intermediate stages of development: (a) both gill and lu

209 d nonlinear dynamic eQTLs, which affect only intermediate stages of differentiation and cannot be fou

210 IL-13 and IL-5 defines CD161(+) NK cells at intermediate stages of differentiation, and is lost upon

211 ed consequences of gene therapy delivered at intermediate stages of disease in a canine model of X-li

212 at arbitrary degrees of partial wetting and intermediate stages of drying.

213 To study the intermediate stages of early and late gastrulation (28-

214 open question is whether and to what extent intermediate stages of EMT promote invasiveness.

215 ells and established cell lines representing intermediate stages of endoderm, mesoderm, ectoderm, and

216 plasmic membranes, apparently immobilized in intermediate stages of envelopment.

217 g BEE, the acquisition and interpretation of intermediate stages of exercise in addition to peak exer

218 is the poor performance for the detection of intermediate stages of fibrosis.

219 ach is available to discriminate between the intermediate stages of fibrosis.

220 Understanding the intermediate stages of fluid-mediated NP self-assembly o

221 rder", i.e., they have similar structures in intermediate stages of folding between the unfolded and

222 DnaK cooperate in the binding of proteins at intermediate stages of folding, assembly, and translocat

223 At intermediate stages of genome assembly projects, when a

224 IFG during the initial to intermediate stages of grammar acquisition in a new targ

225 Analysis of intermediate stages of iMPC induction revealed that exti

226 in alternative splicing during the early and intermediate stages of mammary cancer.

227 ancient associations allow us to investigate intermediate stages of metabolic and anatomical integrat

228 lags behind neural connectivity, leading to intermediate stages of neural activity that are either n

229 opmental systems neuroscience examines these intermediate stages of neural activity, mapping out the

230 aximal chromatin remodeling influence during intermediate stages of neurogenesis by binding as homodi

231 However, as progenitor cells underwent intermediate stages of neuronal differentiation under th

232 in transiently active genomic regions during intermediate stages of neuronal differentiation.

233 These findings provide insight on intermediate stages of NK-cell development, a view of em

234 layed atypical NK cell subsets, representing intermediate stages of NK-poiesis based on single-cell m

235 nodule-expressed genes will help to open the intermediate stages of nodulation to molecular analysis.

236 thrombocytopenias represent a failure in the intermediate stages of PLT production?

237 the nature of transformations that occur in intermediate stages of processing in the ventral visual

238 RNA polymerase (RNAP) trapped in intermediate stages of promoter escape, as well as RNAP

239 teractions may play an important role in the intermediate stages of protein aggregation.

240 e for Hop, which is associated with hsp90 in intermediate stages of protein folding, overlaps with a

241 ree different doses administered at early or intermediate stages of retinal degeneration in the rd7 m

242 use of the lack of in situ structures of the intermediate stages of RNA-dependent RNA polymerase (RdR

243 essing the quality of RNA samples and of the intermediate stages of sample preparation and hybridizat

244 cluster of clusters may be important in the intermediate stages of some cluster growth as exemplifie

245 e statistical maps were highly correlated at intermediate stages of the analysis pipeline.

246 identities of the progenitor populations at intermediate stages of the differentiation process remai

247 eflective foci may reflect signs of early or intermediate stages of the disease.

248 Many intermediate stages of the gene transfer process are rep

249 ght (L) chain was arrested at the H2 and H2L intermediate stages of the T15 wild-type pathway (H2 -->

250 system that allows for the study of possible intermediate stages of this commitment by controlling th

251 l subunits in different complexes trapped at intermediate stages of translocation in solution.

252 Genetic interactions regulating intermediate stages of tubulogenesis in the developing k

253 een autophagy and apoptosis in the early and intermediate stages of viral hepatitis.

254 s for patients with single ventricle include intermediate staging or early Fontan completion to reduc

255 dnisone, and procarbazine were added in TG2 (intermediate stages) or TG3 (advanced stages), respectiv

256 RPN appears to have favorable early-to-intermediate stage outcomes.

257 es revealed that immature and DNA-containing intermediate stage particles accumulated in the absence

258 ng and preconditioning stage, followed by an intermediate stage preparatory for acclimation, and a la

259 One mutant apparently blocks assembly at an intermediate stage prior to oligomerization of the final

260 n by Coulombic interactions and show how the intermediate stages proceed through the formation of a h

261 ne expression were specifically localized to intermediate-stage progenitor cells (IPCs), a type of tr

262 ranscription of a DNA template containing an intermediate stage promoter.

263 nstitute transcription of a template with an intermediate stage promoter.

264 In some patients, an intermediate stage referred to as smoldering multiple my

265 ) have identified cells representative of an intermediate stage (referred to as the formative state)

266 cient quantities of cells at developmentally intermediate stages required for biochemical analysis.

267 is a dynamic process proceeding through many intermediate stages, requiring multiple DNA sites and th

268 ected against CCR5, it was found that at the intermediate stage, SOS-Env had associated with corecept

269 Patients with intermediate-stage squamous cell carcinoma of the head a

270 other cancers with distinct pathways and/or intermediate stages, such as hepatocellular cancer.

271 ZipA-directed PIPS may represent an intermediate stage that connects cell wall elongation to

272 e-aware ancestral reconstructions reveals an intermediate stage that had already lost a large number

273 in signaling is required to progress into an intermediate stage that precedes quiescence and differen

274 approach reveals the existence of transient intermediate stages that are missed by the latter approa

275 d no evidence for a morphologically distinct intermediate stage (the tetraploid type II meront) but d

276 yo-electron microscopy, we show that in this intermediate stage, the E glycoproteins form 60 trimers

277 cause peptide inhibition showed that, at the intermediate stage, the heptad repeats of gp41 have beco

278 We identify five intermediate stages through which a pathogen exclusively

279 lopment, Inlay and colleagues identify novel intermediate stages through which hematopoietic progenit

280 However, the intermediate stages through which individual cells progr

281 in left ventricular end-systolic volume from intermediate stage to peak exercise of >10% predicted CA

282 ndently related to progression from early or intermediate stages to advanced stages of AMD, controlli

283 dent study of progression from no, early, or intermediate stages to advanced subtypes of AMD and will

284 the rare, asynchronous transition from these intermediate stages to iPS cells.

285 heparin-like glycosaminoglycans through the intermediate stages to the end products.

286 groups and for the low and mid doses in the intermediate stage treatment groups.

287 hildren and adolescents with newly diagnosed intermediate-stage (treatment group 2) and advanced-stag

288 tion is generally selected for patients with intermediate-stage tumours or who are medically unfit to

289 le lineages and progress through a series of intermediate stages until fully mature, at which time th

290 n PBMCs lacking CCR5, whereas the early- and intermediate-stage viruses replicated as well in PBMCs l

291 However, no particular intermediate stage was essential for evolving complex fu

292 f peptides to block fusion when added at the intermediate stages was quantified.

293 Intermediate staging was performed in 16 of 46 patients

294 At this intermediate stage, we find that Tim23p forms cross-link

295 lties in processing material to the advanced intermediate stage, we have been successful in developin

296 the beta-sheet hydrogen bonds occurs at the intermediate stage when low-weight oligomers start to fo

297 d formation of atherosclerotic lesions of an intermediate stage, which contained both macrophages and

298 ng evidence that speciation can progress to "intermediate" stages-with populations evolving only part

299 ensing, permitting the identification of new intermediate stages within the transcription activation

300 espiratory motoneurons in the VII nucleus at intermediate stages (XII-XVII) of development.