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1 3 patients were on warfarin with therapeutic international normalized ratio.
2 etransplant cerebral edema and postoperative international normalized ratio.
3 atients underwent ablation under therapeutic international normalized ratio.
4 farin and warfarin can be monitored with the international normalized ratio.
5 sEPCR levels mirrored changes in values for international normalized ratios.
6 ped at creatinine 0.7-2.5, bilirubin 0.3-27, international normalized ratio 0.1-2.6, and sodium 120-1
7 x (creatinine(-0.836) ) x (urea(-0.229) ) x (international normalized ratio(-0.113) ) x (age(-0.129)
8 x (creatinine(-0.836) ) x (urea(-0.229) ) x (international normalized ratio(-0.113) ) x (age(-0.129))
9 to compare the efficacy of warfarin (target international normalized ratio 1.5 to 2.5 IU) plus aspir
10 tinine (0.8 and 3.0 mg/dL, respectively) and international normalized ratio (1 and 3, respectively).
11 lt using cutoff values of 2.2 or greater for international normalized ratio (1 point) and less than 1
12 53.71 IU/L; P = 0.04), and prothrombin time-international normalized ratio (1.16 + 0.36 vs 1.28 + 0.
13 Bilirubin (1.8 vs 2.2 mg/dL; P = .032) and international normalized ratio (1.4 vs 1.5; P = .022) in
14 cipients, postoperative days 7 and 14 median international normalized ratio (1.5 and 1.2, respectivel
15 r compared with RL recipients (7 and 14 days international normalized ratio [1.2, P < 0.001; 1.1, P =
16 , 0.378 vs 0.939 [95% CI, 0.91-0.97]; log(e) international normalized ratio, 1.120 vs 1.658 [95% CI,
17 s demonstrated by normal coagulation values (international normalized ratio, 1.19; reference value, 0
18 y with either adjusted-dose warfarin (target international normalized ratio 2 to 3) or fixed-dose xim
19 ns for high-risk patients (warfarin therapy, international normalized ratio 2.0 to 3.0) and low-risk
20 ned warfarin, the time in therapeutic range (international normalized ratio 2.0 to 3.0) was 62% and 6
22 676 patients with ALF or acute liver injury (international normalized ratio 2.0 without hepatic encep
23 ratory evidence of hypocoagulability (median international normalized ratio = 2.9 and platelet count
26 e of 5 mg twice daily) with warfarin (target international normalized ratio, 2.0 to 3.0) in 18,201 pa
27 e daily) with dose-adjusted warfarin (target international normalized ratio, 2.0 to 3.0) in patients
28 racranial artery to receive warfarin (target international normalized ratio, 2.0 to 3.0) or aspirin (
31 function) versus dose-adjusted VKAs (target international normalized ratio, 2.0 to 3.0, or 3.1 to 4.
33 e morning after surgery, or warfarin (target international normalized ratio, 2.5 [range, 1.8 to 3.0])
34 risk factors randomized to warfarin (target international normalized ratio=2.0-3.0) or rivaroxaban (
35 arallel controls (percentage of out-of-range international normalized ratios 31% versus 42% at 1 mont
37 usions were all independent risk factors for international normalized ratio abnormalities (all p < .0
39 lation tests including prothrombin time, and international normalized ratio, activated partial thromb
40 lanine transaminase, aspartate transaminase, international normalized ratio, acute kidney injury, sep
42 se, stroke history, prior bleeding, unstable international normalized ratio, age >65, drug or alcohol
43 nction, stroke, prior major bleeding, labile international normalized ratios, age 65 years or older,
45 easure of synthetic liver function, based on international normalized ratio and albumin and bilirubin
48 MELD assigns lower weight to creatinine and international normalized ratio and higher weight to bili
49 quiring regular laboratory monitoring of the international normalized ratio and intermittent adjustme
51 F is a continuous score, based on bilirubin, international normalized ratio, and alanine aminotransfe
52 r liver function, anticonvulsant use, labile international normalized ratio, and antihypertensive use
54 ctioned, and serum transaminases, bilirubin, international normalized ratio, and lactate levels corre
55 seline levels of bilirubin, prothrombin time/international normalized ratio, and Model for End-Stage
56 ic biosynthetic capacity, such as albumin or international normalized ratio, and positively with non-
58 the 4 variables (ie, bilirubin, creatinine, international normalized ratio, and sodium) had a modest
59 antly lower blood ammonia, prothrombin time, international normalized ratio, and TGF-beta1 levels whe
60 onal status, serum albumin, serum bilirubin, international normalized ratio, and the presence of asci
62 logy, HE grade, use of IMV and vasopressors, international normalized ratio, and year), although pers
63 tivated partial thromboplastin time <= 50 s, international normalized ratio antithrombin III, fibrino
64 In this study, we validated the admission international normalized ratio as an independent risk fa
66 tients had significantly lower bilirubin and international normalized ratio at waitlisting, and less
67 ary outcomes were percentage of out-of-range international normalized ratios at 1 and 3 months and pe
68 erior to PG-1 for percentage of out-of-range international normalized ratios at 1 month and 3 months
70 utcomes after trauma and compared two common international normalized ratio-based definitions for acu
71 e (for an individual patient) to maintain an international normalized ratio between 2 and 3 was 15.6
72 ntly, warfarin was continued to maintain the international normalized ratio between 2 and 3.5 (group
73 whom were receiving acenocoumarol and had an international normalized ratio between 2.0 and 3.0 durin
74 S-TIPS prognostic index (PI) score (based on international normalized ratio, bilirubin, and age) was
76 s reproduces the empirical equations for the International Normalized Ratio calibration (INR), as wel
78 0 mg (twice daily) was cost-effective unless international normalized ratio control was excellent (ti
79 he risk of hemorrhage was high or quality of international normalized ratio control was poor (time in
81 of hemorrhage or high risk of stroke unless international normalized ratio control with warfarin was
83 mostatic efficacy from start of infusion and international normalized ratio correction (</=1.3) at 0.
85 End-Stage Liver Disease and age, bilirubin, international normalized ratio, creatinine scores), comp
86 d partial prothrombin time, prothrombin time international normalized ratio, D-dimer, tissue plasmino
87 , Bleeding history or predisposition, Labile international normalized ratio, Elderly (>65 years), Dru
88 , Bleeding history or predisposition, Labile international normalized ratio, Elderly [>65 years], Dru
89 , bleeding history or predisposition, labile international normalized ratio, elderly, drugs/alcohol c
90 , bleeding history or predisposition, labile international normalized ratio, elderly, drugs/alcohol c
91 , bleeding history or predisposition, labile international normalized ratio, elderly, drugs/alcohol c
92 , bleeding history or predisposition, Labile international normalized ratio, elderly, drugs/alcohol c
93 oke, bleeding predisposition/history, labile international normalized ratio, elderly, drugs/alcohol)
94 , Bleeding History or Predisposition, Labile International Normalized Ratio, Elderly, Drugs/Alcohol).
95 eding history or predisposition, labile INR [international normalized ratio], elderly, drugs/alcohol
97 y an MTP goal directed by TEG or by CCA (ie, international normalized ratio, fibrinogen, platelet cou
98 concentrations of bilirubin and creatinine, international normalized ratio for prothrombin time (INR
100 to oral anticoagulation (as assessed by the international normalized ratio for prothrombin time).
101 irubin and creatinine concentrations and the international normalized ratio for the prothrombin time.
102 sodium levels] and MELD-XI [does not include international normalized ratio]) for endpoint events, de
103 lasty and receiving warfarin prophylaxis, an international normalized ratio goal of 1.8 compared with
104 age older than 65 years, a prothrombin time international normalized ratio greater than 1.1, alpha-f
105 hy affected 50% of subjects if defined as an international normalized ratio greater than 1.2 and 21%
106 normalized ratio greater than 1.5 but not an international normalized ratio greater than 1.2 identifi
107 Acute traumatic coagulopathy defined as an international normalized ratio greater than 1.2 was not
108 r hemoglobin less than 8 gm/dL (p = 0.0006), international normalized ratio greater than 1.4 (p < 0.0
109 at least one organ system dysfunction and an international normalized ratio greater than 1.4 at basel
110 ing acute traumatic coagulopathy by using an international normalized ratio greater than 1.5 but not
111 e traumatic coagulopathy to patients with an international normalized ratio greater than 1.5 may yiel
112 , acute traumatic coagulopathy defined as an international normalized ratio greater than 1.5 was sign
115 iciency (total bilirubin level > 10 mg/dL or international normalized ratio > 2) occurred in 6 patien
116 included adult patients on warfarin with an international normalized ratio >/=1.5 who received froze
117 serum creatinine level >3 mg/dL or oliguria; international normalized ratio >1.5 or transaminases >5
118 sociation with TIC as defined by laboratory (international normalized ratio >1.5) or clinical (transf
120 y postoperative day 7 bilirubin >10 mg/dL or international normalized ratio >1.6), and graft failure.
121 re at a higher risk for overanticoagulation (international normalized ratio >4; P = 0.052), compared
123 the DCD120'-group had a significantly higher international normalized ratio (>5) compared to the rest
124 elet count < 150x10(3)/mm(3)), coagulopathy (International Normalized Ratio>2.0), and renal insuffici
125 e of continuous renal replacement therapy or international normalized ratio had no effect on clotting
126 1; test for trend across 4 categories of the international normalized ratio), history of coronary art
127 se (HR, 1.35; 95% CI, 1.04-1.75), and labile international normalized ratio (HR, 1.33; 95% CI, 1.04-1
128 .7% vs. 2.5%; p = NS) despite increasing the international normalized ratio in a dose-related fashion
129 , alcoholic etiology, creatinine levels, and international normalized ratio in the overall cohort, an
130 nit mortality (p < .0001), particularly when international normalized ratio increased after intensive
131 0 days of warfarin, age > or = 80 years, and international normalized ratio (INR) > or = 4.0 were ass
132 P < 0.01), platelet <150 U/L (P < 0.01), and International Normalized Ratio (INR) >1.2 (P < 0.01).
135 e recovery was reflected by normalization of International normalized ratio (INR) (80% of patients),
136 , 95% confidence interval [CI] = 1.35-3.21), international normalized ratio (INR) (P < 0.001, HR = 9.
137 ial fibrillation, it is unclear how baseline international normalized ratio (INR) affects the dosing
138 regimens is consistent across a range of the international normalized ratio (INR) among subjects admi
140 We explored the relation between admission international normalized ratio (INR) and acute infarct v
144 Prothrombin time (PT) and the associated international normalized ratio (INR) are routinely teste
145 atment with full-dose warfarin with a target international normalized ratio (INR) between 2.0 and 3.0
146 rch has compared the measures of summarizing international normalized ratio (INR) control over time.
147 the therapeutic range of 2.0 to 3.0 for the international normalized ratio (INR) during the first 12
148 orrelates directly to duration and degree of international normalized ratio (INR) elevation above the
149 ts of serum bilirubin and creatinine levels, International Normalized Ratio (INR) for prothrombin tim
150 defined as platelets lower than 150 x 109/L, international normalized ratio (INR) greater than 1.4, o
151 s the risk of hemorrhage, particularly at an international normalized ratio (INR) greater than 4.0.
154 arfarin on the baseline corrected AUC of the International Normalized Ratio (INR) increased by 2.8 ti
156 substantial treatment by baseline laboratory international normalized ratio (INR) interaction effect
157 us tPA to warfarin-treated patients if their international normalized ratio (INR) is 1.7 or lower, th
158 but effective management is complex, and the international normalized ratio (INR) is often outside th
160 egistry-Get With the Guidelines by admission international normalized ratio (INR) levels: subtherapeu
161 e (AST), alanine aminotransferase (ALT), and international normalized ratio (INR) measurements on adm
162 yridamole 75 mg daily (n = 26) with a target international normalized ratio (INR) of 2 to 3 from June
163 < or = 5 mg and > 5 mg necessary to keep an international normalized ratio (INR) of 2.5 to 3.5, and
164 days 1 through 11 of therapy and to a target international normalized ratio (INR) of either 1.8 or 2.
165 cument the increased risk for stroke when an international normalized ratio (INR) of less than 2.0 is
169 warfarin daily dosage needed to reach target international normalized ratio (INR) represented the mai
172 g warfarin dose and the number of predefined international normalized ratio (INR) thresholds for each
174 5th, 75th percentiles) time from most recent international normalized ratio (INR) to ICH was 13 days
177 nts with CF-LVADs have suggested that target international normalized ratio (INR) values <2.5 (range,
178 tients treated with warfarin with a range of International Normalized Ratio (INR) values as well-char
179 However, these variants also affect early international normalized ratio (INR) values during warfa
180 nticoagulation, with the full effect seen at international normalized ratio (INR) values of 2.0 or gr
182 Percent time in therapeutic range (TTR) and international normalized ratio (INR) variability both me
183 percent time in therapeutic range (TTR) and international normalized ratio (INR) variability predict
185 outcome was the percentage of time that the international normalized ratio (INR) was in the therapeu
187 hen compared with holding warfarin until the international normalized ratio (INR) was normal (n = 258
188 itamin K antagonist was recommended, and the international normalized ratio (INR) was not to be measu
189 s of interest: age <1 year, total bilirubin, international normalized ratio (INR), albumin, growth fa
190 e of hepatotoxicity (ALT > 1,000 IU/L), peak international normalized ratio (INR), and adverse drug r
191 oplastin time (APTT), prothrombin time (PT), international normalized ratio (INR), and concentration
192 (AST), day-1 lactate, day-3 bilirubin, day-3 international normalized ratio (INR), and day-7 AST were
193 ctivated partial thromboplastin time (APTT), international normalized ratio (INR), and other measures
194 donor age (DnAge), serum creatinine (Creat), International Normalized Ratio (INR), and serum albumin
195 tracranial hemorrhage with regard to age and international normalized ratio (INR), controlling for co
196 on control with warfarin, as assessed by the international normalized ratio (INR), is challenging.
197 ctivated partial thromboplastin time (aPTT), international normalized ratio (INR), platelet count and
201 with LT or death: age, etiology; coma grade; international normalized ratio (INR); serum pH; body mas
202 unger age (OR, 0.92; p = 0.004), lower index international normalized ratio (INR; 0.31; p = 0.03), an
203 ndrome: warfarin-associated supratherapeutic international normalized ratio (INR; median, 6.5) at ons
204 rcentage of time in the target range for the international normalized ratio (INR; target range, 2.0 t
205 (7.6%) were receiving therapeutic warfarin (international normalized ratio [INR] >/=2) and 8290 (8.8
206 aracterized by sudden onset of coagulopathy (international normalized ratio [INR] >= 1.5) and encepha
207 l coagulation assessment than routine tests (international normalized ratio [INR] and platelet [PLT]
208 l coagulation assessment than routine tests (international normalized ratio [INR] and platelet count)
209 alyzed altered prothrombin time (measured as international normalized ratio [INR]) after initiation o
210 s, response to therapy (as determined by the international normalized ratio [INR]), and bleeding even
212 female), 3087 (9.4%) had used a VKA (median international normalized ratio [INR], 1.5 [IQR, 1.2-1.9]
214 tween MELD-GRAIL-Na (re-estimated bilirubin, international normalized ratio [INR], sodium, and GRAIL)
216 eparin, warfarin-associated supratherapeutic international normalized ratios (INRs), and evidence of
217 ted with vitamin K antagonists have unstable International Normalized Ratios (INRs), increasing the r
221 ith patients who often failed to meet target international normalized ratio level (HR: 3.53, 95% CI:
222 rin who consistently achieved minimum target international normalized ratio levels or those on acetyl
223 er, hypertriglyceridemic events and abnormal international normalized ratio levels were more common a
224 nd alanine aminotransferase, and prothrombin international normalized ratio; LR, 0.09; 95% CI, 0.03-0
226 ns (P = 0.012), coagulation status on POD 7 (international normalized ratio < 1.4; P = 0.027), and pr
227 ulation with NOACs versus those on warfarin (international normalized ratio <1.7) or not on anticoagu
228 ne triglyceride level <= 154 mg/dL, baseline international normalized ratio <= 1, baseline aspartate
229 idence interval, 1.51-6.51; P=0.002) and the international normalized ratio measured prior LT (OR=4.9
230 preoperative pulmonary testing and a higher international normalized ratio measured prior LT were as
232 ass rates included coronary risk assessment, international normalized ratio measured, HbA1c measureme
233 3.4 [5.0] vs -7.8 [6.9]; P = .02), and worst international normalized ratio (median [interquartile ra
234 model for end-stage liver disease excluding international normalized ratio (MELD-XI score), as well
235 Model for End-Stage Liver Disease Excluding international normalized ratio (MELD-XI) score at the ti
237 perative temperature less than 95 degrees F, international normalized ratio more than 1.5, or a pH le
238 t cerebral edema and a higher posttransplant international normalized ratio (odds ratios and 95% conf
239 luded a prothrombin time of 15.4 seconds, an international normalized ratio of 1.2, and a partial thr
240 f warfarin (at a dose adjusted to produce an international normalized ratio of 1.4 to 2.8) and that o
241 rction patients, warfarin therapy (at a mean international normalized ratio of 1.8) combined with low
242 The warfarin dose was adjusted to obtain an international normalized ratio of 2 to 3 or 2.5 to 3.5 o
243 bo-controlled trial of warfarin targeting an international normalized ratio of 2.0 to 3.0 in patients
244 to determine whether warfarin (with a target international normalized ratio of 2.0 to 3.5) or aspirin
245 linical trial of open-label warfarin (target international normalized ratio of 2.5 to 3.0) and double
246 udies revealed a normal white-cell count, an international normalized ratio of more than 11, a prothr
247 mg/dL; female, 0.58 [0.64] mg/dL; P < .001; international normalized ratio of prothrombin rate: male
248 to calculate the MELD score were available (international normalized ratio of prothrombin time, tota
251 .85; 95% confidence interval, 0.79-0.92) and international normalized ratio (OR, 1.45; 95% confidence
252 rial fibrillation (OR: 5.19), subtherapeutic international normalized ratio (OR: 7.37), increased cus
253 antithrombin levels (p = 0.02), but not with international normalized ratio (p = 0.99) or activated p
254 artate aminotransferase and prothrombin time-international normalized ratio; postoperative morbidity
256 ement, variability in prothrombin time-based international normalized ratio (PT-INR) is caused, in pa
257 erative serum bilirubin and prothrombin time-international normalized ratio (PT-INR) levels were also
258 ity (r=0.97), prothrombin time (r=0.77), and international normalized ratio (r=0.72) but less so with
263 in treatment is maintenance of a therapeutic international normalized ratio, regardless of the age of
266 model for end-stage liver disease excluding international normalized ratio score) were assessed prei
267 ed Kingdom End-Stage Liver Disease) included international normalized ratio, serum creatinine, biliru
268 rained, baseline hemoglobin, platelet count, international normalized ratio, serum sodium, creatinine
270 itoring, the difficulties in maintaining the international normalized ratio target (variable between
271 frozen plasma required to reach an arbitrary international normalized ratio target, limitations of th
272 ring devices, patients can conduct their own international normalized ratio testing and dose adjustme
275 in time in critically ill patients using the international normalized ratio to standardize data and e
276 ables (hemoglobin, alkaline phosphatase, and international normalized ratio), together with important
277 oagulopathy (OR: 3.1, 95% CI: 1.7 to 5.8 per international normalized ratio unit), and in those recei
278 nsive care unit stay, but the pretransfusion international normalized ratio value varied widely.
279 care unit admissions, 30% developed abnormal international normalized ratio values (defined as an int
281 ong independent association between abnormal international normalized ratio values and greater intens
282 onist therapy can be complicated by unstable international normalized ratio values and patient-relate
285 (SD) base deficit was -9.8 (6.3), and median international normalized ratio was 1.3 (interquartile ra
289 tients and 40% to nonbleeding patients whose international normalized ratio was normal or only modest
291 ion of total treatment time during which the international normalized ratio was within the therapeuti
292 nalysis, recipient's age and elevated pre-LT international normalized ratio were associated with incr
293 tes, albumin, bilirubin, platelet count, and international normalized ratio were independent predicto
294 l thromboplastin time, prothrombin time, and international normalized ratio were reduced from warfari
295 Mean warfarin treatment was 1 year; mean international normalized ratios were 1.9 (IPAH) and 2.0
298 0044) and took longer to reach a therapeutic international normalized ratio with rivaroxaban versus w
299 ges (P = 0.0002), spent less time with their international normalized ratio within the target range (
300 warfarin at a dose adjusted to maintain the international normalized ratio within the therapeutic ra