ライフサイエンスコーパス: interneuronal

1 pike timing, potentially as a consequence of interneuronal abnormalities reflected by reduced parvalb

2 nism for hetero- and homosynaptic control of interneuronal activity and acetylcholine release in the

3 ed during seizures increases hippocampal CA3 interneuronal activity and suggests that a loss or impai

4 tamatergic and GABAergic inputs, synchronous interneuronal activity can produce a depolarizing synapt

5 ol of sympathetic preganglionic activity and interneuronal activity in the rat.

6 to the observed delay of firing, so that the interneuronal activity leads the burst cycle.

7 In contrast, somatostatin-expressing interneuronal activity peaks significantly later, and fi

8 are thus important in initiating the intense interneuronal activity triggered by kainate, which in tu

9 Pyramidal and interneuronal activity was phase-locked not only to larg

10 nes were enriched for neuronal, specifically interneuronal, affiliations and coded a network of prote

11 ttributable to competition between segmental interneuronal and descending bulbospinal inputs, which r

12 d no direct synaptic connections between the interneuronal and motoneuronal elements that generate th

13 auditory epithelial cell synapses resembles interneuronal and nerve-muscle synapses, thereby definin

14 n is a bioactive neuropeptide that modulates interneuronal and neuromuscular synaptic transmission in

15 x depends on the preponderant involvement of interneuronal and principal cell networks, respectively.

16 ppocampus studied here, the profound loss of interneuronal and principal cell populations and consequ

17 pressed on a variety of cholinergic sensory, interneuronal, and motor neurons in myenteric ganglia.

18 s suggest that RGS4-dependent attenuation of interneuronal autoreceptor signaling is a major factor i

19 first documentation of gap junctions between interneuronal axon terminals in the mammalian forebrain.

20 Dephrin or DEph causes the abberant exit of interneuronal axons from the CNS, whereas ectopic expres

21 Both inhibitors caused interneuronal axons that normally would grow along the l

22 on and is also required for guidance of some interneuronal axons The involvement of Dock in the conve

23 gions of the GABAergic perisomatic-targeting interneuronal axons, including the parvalbumin-expressin

24 Interneuronal bursting is time-locked to glutamatergic b

25 BLA via actions on both projection cells and interneuronal cell populations.

26 n GABAergic modulation of deep pyramidal and interneuronal cell populations.

27 V1 INs differentiates as Renshaw cells, the interneuronal cell type that mediates recurrent inhibiti

28 lls biased to the production of cones and an interneuronal cell type, the horizontal cell (HC).

29 e mechanisms that generate these specialized interneuronal cell types from multipotential spinal prog

30 psychiatric disorders and encompass multiple interneuronal cell types.

31 n (1 sec) of a peripheral nerve activates an interneuronal central pattern generator that produces th

32 dal locomotion and may reflect activation of interneuronal central pattern-generating circuits.

33 The first might reflect interneuronal changes linked by gap junctions, whereas t

34 egulation of fast excitatory transmission at interneuronal cholinergic synapses in Drosophila.

35 Through live imaging of interneuronal cilia, we show that migrating interneurons

36 changes in the strength of a specific spinal interneuronal circuit: spinally mediated reciprocal Ia i

37 ss of SCN timekeeping is further enhanced by interneuronal, circuit-level coupling.

38 Deciphering the interneuronal circuitry is central to understanding brai

39 To determine the extent to which interneuronal circuitry studied with one approach can tr

40 Moreover, the ability to modulate local interneuronal circuits by tACS in a behaviorally relevan

41 ons to explore the possible ramifications of interneuronal circuits containing separate classes of GA

42 n of hip-mediated sensory feedback to spinal interneuronal circuits during dynamic conditions in peop

43 The expression of these spinal interneuronal circuits during imposed sinusoidal hip mov

44 serve coincidence detection, these cortical interneuronal circuits may be essential for salience sel

45 recordings, we found two previously unknown interneuronal circuits that link cortical layer 1-3 (L1-

46 ynchronization of oscillations in inhibitory interneuronal circuits, supporting the hypothesis that t

47 We propose that spinal GABAb-ergic interneuronal circuits, which are sensitive to baclofen,

48 cally depend on synaptic interactions within interneuronal circuits.

49 The activation profiles of the two interneuronal classes are temporally offset, with the pa

50 Both interneuronal classes participate in the feedfoward inhi

51 rrelates with the level of activity for both interneuronal classes.

52 ts indicate that OPCs are a direct target of interneuronal collaterals and that the GABA-induced Cl(-

53 ethyl-D-aspartate receptors (NMDARs) mediate interneuronal communication and are broadly involved in

54 ation is critical for efficient and coherent interneuronal communication and, as revealed in animal s

55 channel and its associated impairment of SCN interneuronal communication lead to major deficits in th

56 y role for CaM-KII in shaping and regulating interneuronal communication, regardless of its modality.

57 The metabolic cost engendered in sustaining interneuronal communications has emphasized the viabilit

58 tify V1- and V2b-derived neurons as the core interneuronal components of the limb central pattern gen

59 network with speed-dependent recruitment of interneuronal components.

60 n Renshaw cell raises the possibility that R-interneuronal connections are formed precisely from the

61 ect evidence for a decrease in plasticity of interneuronal connections as animals make the transition

62 ctly on GnRH-1 neurons or indirectly through interneuronal connections.

63 for primary cilia-mediated GPCR signaling in interneuronal connectivity and inhibitory circuit format

64 ndrite elaboration influences the pattern of interneuronal connectivity and network function.

65 Interneuronal connectivity patterns and laminar distribu

66 Excitatory interneuronal connectivity within lamina II exhibited a

67 is associated with changes in the pattern of interneuronal connectivity within the segmental spinal c

68 disinhibition can be achieved despite dense interneuronal connectivity, even with random connections

69 e with a knockout of the neuronal (primarily interneuronal) connexin36.

70 oncomitant with an increase in the number of interneuronal contacts and cessation of neurite growth.

71 The results identify the pattern of interneuronal correlation in neural populations as a tar

72 by an ensemble of hundreds of neurons whose interneuronal correlation mimics that of the visual cort

73 Previously, we reported the strength of interneuronal correlation of spike count on the time sca

74 We analyzed the magnitude and interneuronal correlation of the variability in the acti

75 vity or variability of the response, nor the interneuronal correlation unexplained by the stimulus ("

76 We found that weak interneuronal correlation, or synchrony, allows the vari

77 visual fixation) influences the structure of interneuronal correlations and the accuracy of populatio

78 Interneuronal correlations and the representation of dif

79 ous cylinders was positively correlated with interneuronal correlations and was specifically associat

80 model, choice probability and task-specific interneuronal correlations emerge from plasticity of top

81 Interneuronal correlations for a perceptually ambiguous

82 We tested whether training changes interneuronal correlations in the dorsal medial superior

83 tion cylinders may be controlled by enhanced interneuronal correlations on longer timescales.

84 stimulus-specific changes in the pattern of interneuronal correlations that enhance the ability of n

85 correlated variability, and that using these interneuronal correlations yields oculomotor predictions

86 al and perceptual sensitivity, strengthening interneuronal correlations, and facilitating correlation

87 o supraoptic nucleus (SON) neurons increases interneuronal coupling in slices from lactating but from

88 Additionally, activation results in interneuronal coupling increases that are capable of bei

89 We show that interneuronal cytosolic coupling is severely reduced by

90 lyses and some genetic studies have reported interneuronal deficits and involvement of the DISC1, NRG

91 y using laser ablations or mutant lines with interneuronal deficits.

92 rites, the structural changes we observed in interneuronal dendritic arbors suggest that optic tectal

93 As interneuronal dendritic electrical coupling is almost ab

94 ent postsynaptic to asymmetrical contacts on interneuronal dendritic shafts.

95 g rate of a single MI cell; however, we find interneuronal dependencies in MI to be much more locked

96 , and/or (3) not incorporated the effects of interneuronal dependencies on firing rate.

97 A surprising feature of interneuronal development is the large extent of structu

98 Finally, we show that interneuronal DISC1 affects NRG1-ErbB4-mediated phenotyp

99 Neither a blockade of interneuronal discharge nor antagonists of several neuro

100 ed in several respects from previous data on interneuronal discharge patterns in anesthetized animals

101 ion was necessary for the synchronization of interneuronal discharge, which strongly supports a synap

102 enia in relation to neuronal orientation and interneuronal distance.

103 image analysis computer software we measured interneuronal distances and neuronal orientation.

104 There was no accompanying alteration of interneuronal distances, neuronal orientation.

105 ork coherence, indicating that plasticity of interneuronal diversity is likely to be an important mec

106 rneurons and neurogliaform cells, as well as interneuronal diversity itself, as important factors in

107 Interneuronal diversity reflects the division of labor b

108 tworks, and suggest a physiological role for interneuronal diversity.

109 ver after 8-10 days, striatal projection and interneuronal dynamics did not-eventually entering a non

110 on will likely be important in understanding interneuronal dysfunction following excitotoxic injury.

111 riety of conditions attributed to inhibitory interneuronal dysfunction, such as epilepsy, anxiety dis

112 In conclusion, the PRC possesses specific interneuronal equipment with unusually high proportion o

113 synaptic principal cells, and the control of interneuronal excitability is an important regulator of

114 During the late preictal phase, interneuronal excitability was high, but IPSCs, evoked b

115 These data demonstrate that interneuronal excitatory cholinergic synapses in Drosoph

116 nct anatomical and neurochemical features of interneuronal excitatory synapses.

117 fng is not required for the role of Notch in interneuronal fate choice, which we show is mediated by

118 ymmetric type: one is Engrailed positive (of interneuronal fate); and one is Engrailed negative (of e

119 These observations suggest that interneuronal firing elicits a GABAB-receptor-mediated e

120 However, what controls interneuronal firing remains incompletely understood.

121 tial of OPC GABA(A) currents was -43 mV, and interneuronal firing was correlated with transient depol

122 OS-evoked hyperpolarizations closely matched interneuronal firing, suggesting that HVc interneurons m

123 e over excitatory actions and thus moderates interneuronal firing.

124 As a test, the impact of dopamine on interneuronal GABA(A) receptor function was studied by c

125 gm model to evaluate the correlation between interneuronal GABAergic network activity and seizure-lik

126 fast onset pattern is mainly contributed by interneuronal (gamma-aminobutyric acidergic) signaling,

127 Interneuronal gap junctional coupling is a hallmark of n

128 After injury, interneuronal gap junctional coupling may mediate signal

129 nt of selective blockers of connexin36-based interneuronal gap junctions could be of therapeutic valu

130 This suggests that Cx36 interneuronal gap junctions selectively contribute to ga

131 Furthermore, the results indicate that interneuronal heterogeneity can change in neurological d

132 tial, indicating that lasting alterations in interneuronal heterogeneity can take place in real neuro

133 response profiles varied depending on their interneuronal horizontal distances.

134 In contrast, interneuronal inhibition was readily detected, comprisin

135 relatively weak--in contrast to feedforward interneuronal inhibition, which exerts strong effects on

136 s, in what way the spatiotemporal pattern of interneuronal input affects principal cell activity, and

137 ns in the peri-LC dendritic zone may provide interneuronal integration for LC noradrenergic neurons.

138 embrane protein-2 (VAMP-2) in neurons at the interneuronal junction of the central nervous system.

139 raffics from peripheral nerve endings to the interneuronal junction, there is limited understanding o

140 is is due to the fast activation kinetics of interneuronal K(+) currents.

141 Interneuronal kainate receptors (KARs) regulate GABAergi

142 organized hierarchically and contains three interneuronal levels, including two upper levels of "com

143 etinin (CalR) and GABA, markers that suggest interneuronal lineage.

144 s and overexpression of the early motor- and interneuronal marker islet.

145 labeled by using antibodies to a variety of interneuronal markers including parvalbumin (PV), vasoac

146 onally, Y1r-ir was also colocalized with the interneuronal markers studied.

147 in (~22%) or calretinin (~11%) but not other interneuronal markers, suggesting that BLA neurons proje

148 period of corticogenesis and colocalize with interneuronal markers, suggesting that they play a role

149 inhibition of granule cells may provide the interneuronal mechanism for CFR-induced SS modulation.

150 ovide evidence for this by investigating the interneuronal mechanisms mediating behavioral choice bet

151 Our findings suggest that hippocampal interneuronal microcircuits are preferentially active du

152 reveals specific deficits in the patterns of interneuronal migration along the top of the developing

153 in interactions, modulate distinct routes of interneuronal migration and the consequent positioning o

154 of the Arx gene impairs GABA and cholinergic interneuronal migration but results in a neonatal lethal

155 hat the guidance cue receptors essential for interneuronal migration localize to interneuronal primar

156 n to cause Joubert syndrome induce defective interneuronal migration, suggesting that defects in cili

157 teracts with alpha3beta1 integrin to promote interneuronal migration.

158 Finally, an in silico interneuronal model incorporating the Kidins220-induced

159 iliary GTPase Arl13b in interneurons impairs interneuronal morphology and synaptic connectivity, lead

160 eizures in the entorhinal cortex starts with interneuronal network activity accompanied by a fast and

161 racellular potassium increases associated to interneuronal network activity consistently preceded the

162 We conclude that in the 4-AP seizure model, interneuronal network activity occurs before 4-AP-induce

163 th reduction of neuronal firing and enhanced interneuronal network activity.

164 In turn, the interneuronal network can presumably maintain subthresho

165 Inhibitory interneuronal network gamma (ING) oscillations may arise

166 Here we describe an interneuronal network in the marine mollusk Tritonia dio

167 rons may serve as an important mechanism for interneuronal network plasticity.

168 rhythmic activity, presumably arising in the interneuronal network, was blocked by the GABA(A) recept

169 minals, indicative of the existence of a CCK interneuronal network.

170 her depends on the reconfiguration of shared interneuronal networks [1].

171 Interneuronal networks in neocortex underlie feedforward

172 s could constitute an important component of interneuronal networks in the ABL.

173 Our data demonstrate the involvement of interneuronal networks in the initiation of low-voltage

174 e bilateral, possibly related to commissural interneuronal networks involved in central pattern gener

175 nd developmental disorders, the diversity of interneuronal networks is compromised because of disturb

176 st time, we provide evidence that the spinal interneuronal networks linking the forelimbs and hindlim

177 work indicated that many pattern-generating interneuronal networks may have a modular organization a

178 afferent drives project onto the same spinal interneuronal networks that encode locomotor muscle syne

179 ave predicted that the stable states of such interneuronal networks will be either synchrony (near ze

180 Simulated interneuronal networks with fast and slow synaptic kinet

181 lbar projection neurons by way of inhibitory interneuronal networks, allowing the projection neurons

182 l output cells and the related intracortical interneuronal networks.

183 parameters influence the firing patterns of interneuronal networks.

184 combinations of a small number of modules in interneuronal networks.

185 ion and re-engagement of rostrocaudal spinal interneuronal networks.

186 In particular, interneuronal neuropeptides appear to play roles in cogn

187 euronal density suggests that a reduction in interneuronal neuropil may constitute the anatomical sub

188 nal loss, neuronal metabolic dysfunction, or interneuronal neuropil reduction in the hippocampal regi

189 V-101 in humans, consistent with blockade of interneuronal NMDAR blockade.

190 ed activity is complicated by the effects of interneuronal "noise" correlations between sensory neuro

191 ctural analysis revealed that in addition to interneuronal nuclei, ERalpha-I was affiliated with the

192 ulin-like growth factor-1 partially restored interneuronal number and reduced hypertrophy in some sub

193 is partially suppressed by the dentate gyrus interneuronal output in the intact brain.

194 caudal medulla serves as the final premotor interneuronal output system for vocalization.

195 This suggests that convergent interneuronal pathways exist which generate CMMCs.

196 En expression contributes to some aspect of interneuronal phenotype.

197 as Abeta1-40/42 and phospho-tau may increase interneuronal plaques and intraneuronal tangles, present

198 We report a mechanism of interneuronal plasticity that leads to the functional en

199 ental data demonstrate that modifications in interneuronal population variance influence the behaviou

200 e of cell to cell variability within defined interneuronal populations and the application of the Sha

201 ablish the pyramidal, granule, and GABAergic interneuronal populations as consisting of 7000, 400, an

202 at there is a speed-dependent recruitment of interneuronal populations during locomotion and suggest

203 n/ex vivo experiments confirms that specific interneuronal populations exhibit reduced dendritic comp

204 A life-long turnover of sensory and interneuronal populations has been documented in the olf

205 ect some convergence of pathways on the same interneuronal populations involved in the regulation of

206 ituation where the axons of new afferent and interneuronal populations must insert into a highly spec

207 We identified spinal interneuronal populations targeted by the CST in the cer

208 These studies identified several interneuronal populations that may be involved in the hi

209 out the identity and contribution of defined interneuronal populations to mammalian locomotor behavio

210 ter construct differentiates between the two interneuronal populations.

211 ce of a particular parameter within specific interneuronal populations.

212 regulating the variance of key parameters in interneuronal populations.

213 s that distinguish excitatory and inhibitory interneuronal populations.

214 loping cortical plate, resulting in aberrant interneuronal positioning throughout the cerebral cortex

215 s in the olfactory bulb and continue to form interneuronal precursors into adulthood.

216 influences the differentiation of olfactory interneuronal precursors.

217 tial for interneuronal migration localize to interneuronal primary cilia, but their concentration and

218 laminar restriction of RGC dendrites and the interneuronal processes that synapse on them were not de

219 To test these hypotheses, we compared interneuronal progenitors in the medial ganglionic emine

220 ycine treatment did not affect the number of interneuronal progenitors.

221 (Even-skipped), and defects in serotonergic interneuronal projections.

222 The interneuronal propagation of aggregated tau is believed

223 e hypothesis that changes in the variance of interneuronal properties (e.g. in the degree of scatteri

224 ic afferent forms multiple contacts with the interneuronal proximal dendritic arbor, preferentially n

225 The stability of interneuronal pseudorabies virus labeling patterns follo

226 tation is commonly attributed to the loss of interneuronal regulation by inhibitory D(2) dopamine rec

227 The interneuronal response involves intense activation of bo

228 There is a rapid interneuronal response to focal activity in cortex, whic

229 l networks, arising from a rapid feedforward interneuronal response to focal activity.

230 s demonstrate that the plastic nature of the interneuronal resting membrane potential underlies a uni

231 lices suggests that synergy does not rely on interneuronal signaling and may occur within single subc

232 Hence, neuropeptidergic interneuronal signaling confers a canonical property upo

233 Finally, we show that interneuronal signaling is sufficiently powerful to main

234 Neurotransmitters are essential for interneuronal signalling, and the specification of appro

235 To characterize interneuronal signals responsible for robust pacemaking

236 capable of exerting cell-specific effects on interneuronal signals?

237 ostsynaptic inhibition of several downstream interneuronal sites in the startle circuit.

238 y underlying habituation occurs primarily at interneuronal sites.

239 itive firing evoked by the activation of the interneuronal somatic/dendritic KA receptors.

240 c tectum, which are distributed with a wider interneuronal spacing than in Neognathae.

241 erneuronal subtypes might change, and entire interneuronal species can be lost from the network.

242 of labor between numerous highly specialized interneuronal species, each performing a set of specific

243 ment of the number and relative abundance of interneuronal species.

244 ses the evoked IPSC indirectly by increasing interneuronal spiking and GABA release, leading to activ

245 ntaneous GABA release through an increase in interneuronal spiking.

246 etected in the brain on day 1 PI, with rapid interneuronal spread of infection leading to death by da

247 he flow of descending signals to the modular interneuronal structures of the spinal cord.

248 GAD67 downregulation occurs in multiple interneuronal sub-populations, including the parvalbumin

249 addition to the complete or partial loss of interneuronal subgroups, heterogeneity can also be alter

250 min-positive (PV+) interneurons are the main interneuronal subpopulation exhibiting alpha1 immunoreac

251 parvalbumin-positive INs (PV-INs), the major interneuronal subpopulation in BLA, in the disinhibitory

252 PV) was used as a marker for the predominant interneuronal subpopulation in this nucleus.

253 e is known about the synaptic outputs of the interneuronal subpopulation that expresses somatostatin

254 Although previous studies have shown that interneuronal subpopulations containing parvalbumin (PV)

255 and calbindin-D28K (CB) labeled two separate interneuronal subpopulations in the ABL.

256 dicate that there are at least four distinct interneuronal subpopulations in the ABL: (1) PV+ neurons

257 e is known about the connections of specific interneuronal subpopulations in this region.

258 pendent protein kinase II, whereas different interneuronal subpopulations were labeled by using antib

259 o regulating the excitability of the primary interneuronal subtype in the bulb, M1 receptors regulate

260 A similar interneuronal subtype was also found in GAD65-EGFP-negat

261 These newly identified interneuronal subtypes appeared to be closely related to

262 Immunocytochemical analysis for different interneuronal subtypes demonstrates that ectopia contain

263 gamma-frequency range, the role of distinct interneuronal subtypes in slow (<60 Hz) and fast gamma s

264 auma and seizures, the relative abundance of interneuronal subtypes might change, and entire interneu

265 r properties of GABAergic input on different interneuronal subtypes might have important consequences

266 e mammalian cerebral cortex the diversity of interneuronal subtypes underlies a division of labour su

267 scillation-dependent discharges by two major interneuronal subtypes, the perisomatically projecting p

268 romiscuous gap junctions formed with various interneuronal subtypes, volume transmission, and the abi

269 tion, specification or migration of specific interneuronal subtypes.

270 To test roles for agrin in interneuronal synapse formation, we studied hippocampi f

271 it targets specific receptor subtypes to the interneuronal synapse in vivo.

272 sis coli protein (APC) as a key regulator of interneuronal synapse maturation.

273 etylcholine receptors (nAChRs) at developing interneuronal synapses and report the isolation of trans

274 The kinetics of cholinergic currents at interneuronal synapses are dictated by the peripheral ta

275 ce in the mechanisms that govern assembly of interneuronal synapses as compared to the neuromuscular

276 erlies the formation of the diverse types of interneuronal synapses but differs from that responsible

277 Moreover, interneuronal synapses exhibited higher rates of spontan

278 on was connected to another neuron, not only interneuronal synapses, but also the autaptic synapses o

279 At interneuronal synapses, neuregulin ErbB receptors associ

280 atterning of a presynaptic marker at certain interneuronal synapses.

281 acetylcholine receptor (nAChR) targeting to interneuronal synapses.

282 etal neuromuscular junctions and cholinergic interneuronal synapses.

283 amplitude, charge, and RRP size compared to interneuronal synapses.

284 Neuronal pairs formed both interneuronal synaptic and autaptic connections indiscri

285 hat both acetylcholine and GABA mediate fast interneuronal synaptic transmission in Drosophila.

286 rons may modulate gamma frequency by shaping interneuronal synchronization.

287 potentials may be a critical determinant of interneuronal synchronous bursting in the hippocampus.

288 ate connections of afferents to a functional interneuronal system are clearly present by the eighth i

289 e and physiological actions suggest that the interneuronal system of neuropeptides is crucial for mai

290 r neurons of the pharynx via a glutamatergic interneuronal system.

291 rain, relegating muscle activation to spinal interneuronal systems.

292 s, which may spread throughout the cortex by interneuronal tau transfer.

293 escence and electron microscopy suggest that interneuronal terminals are in direct contact with OPCs,

294 monstrations that the secretion, uptake, and interneuronal transfer of tau can be modulated by diseas

295 observed between cells of differing putative interneuronal type, arguing against gap junctions as the

296 rence to arbors of an abundant, well-defined interneuronal type.

297 GABAergic interneuronal types are silenced or fire during these ev

298 nd phase-preferential discharges of distinct interneuronal types spontaneously emerged from the isola

299 Interneuronal unitary IPSCs are several times larger bec

300 there were parameter ranges where increased interneuronal variance decreased the inhibition of princ