ライフサイエンスコーパス: interpretable

1 erved dynamical variable and is biologically interpretable.

2 arned in hidden layers of the neural network interpretable.

3 adata, is automatically fit, and intuitively interpretable.

4 that are both reproducible and biologically interpretable.

5 easibly large sample sizes and often are not interpretable.

6 roaches were predictive, they were minimally interpretable.

7 uplex ultrasound and x-ray, 822 (99.5%) were interpretable.

8 posed methods are readily understandable and interpretable.

9 dels that were equally predictive yet highly interpretable.

10 CCTA studies although the majority remained interpretable.

11 it, Rpn1, are now well resolved and rendered interpretable.

12 a processing algorithms that render it human-interpretable.

13 such analyses must be scalable, and ideally interpretable.

14 inferences, nor too large to be biologically interpretable.

15 roaches to adapt complex 3D measures into an interpretable 2D view, and a novel way to assess the qua

16 ary, this simple protocol should help enable interpretable analyses of tissue immune responses.

17 Machine learning algorithms that are both interpretable and accurate are essential in applications

18 DUI curves of blending processes are easily interpretable and adaptable for blending monitoring and

19 Decision trees are interpretable and are therefore used extensively through

20 These are clearly interpretable and can be used for predictions; however,

21 ent probabilities from DESC are biologically interpretable and can reveal both discrete and pseudotem

22 of genomic data has underscored the need for interpretable and comprehensive analyses that can captur

23 To tackle these problems, we present an interpretable and efficient web-server, namely FUEL-mLoc

24 -to-affinity models based on a biophysically interpretable and extensible model of protein-DNA intera

25 d a linear regression approach and relies on interpretable and independently tunable parameter thresh

26 assessment approach that provides an easily interpretable and informative result.

27 perior performance in preserving most of the interpretable and meaningful data.

28 er, the beta-value is much more biologically interpretable and needs to be reported when M-value meth

29 This finding provides an interpretable and parsimonious explanation for previous

30 First, sparse factors are interpretable and provide biological insight into mechan

31 ngle- versus multi-cue model are also easily interpretable and related to other variables of interest

32 ontrastive PCA that extracts sparse, stable, interpretable and relevant biological signal.

33 FCDR is particularly interpretable and relevant to the results of CBMA, contr

34 eful characterization of each line to assure interpretable and reproducible experiments.

35 SCMs are directly interpretable and reveal that a logic based on local, no

36 he method can correctly recover biologically interpretable and statistically significant differences

37 w that the output of both mEN and mLASSO are interpretable and they perform significantly better than

38 ose a robust, PAS motif agnostic, and highly interpretable and transferrable deep learning model for

39 Most supine radiographs (>75%) were non-interpretable and were excluded from the study.

40 n size than competing methods (and thus more interpretable) and are significantly enriched in functio

41 of this biomarker is in its highly accurate, interpretable, and generalizable performance for enhance

42 POTTER is a novel, interpretable, and highly accurate predictor of in-hospi

43 nsiderable promise as a nonlocalized, easily interpretable, and reliable tool to access the efficient

44 narrowly defined questions, provide readily interpretable answers, and use true gold standards for d

45 hazard ratio for a binary health outcome is interpretable as an adjusted odds ratio: the odds for th

46 yses of individual microfossils present data interpretable as evidencing the cellular preservation of

47 ko family Pygopodidae (where birth rates are interpretable as speciation rates), the GMRF-based model

48 We find that a single extra parameter, interpretable as the "linking rate," by which bound TFs

49 in Russia and Ukraine (where birth rates are interpretable as the rate of accumulation of new infecti

50 In these cases, HINGE outputs a visually interpretable assembly graph that encodes all possible f

51 cales, while still being easy to compute and interpretable at a glance.

52 ormation flow in these networks will be most interpretable at the population level, particularly for

53 t is that the neural code of human memory is interpretable at the single-neuron level.

54 is performed using standard Excel worksheets interpretable "at-a-glance" and adjustable to the partic

55 er allosteric proteins in general to provide interpretable atomistic representations of their otherwi

56 d a mean of 31 electrodes per patient showed interpretable atrial electrograms.

57 g it well-suited for providing standardized, interpretable, automatable, and scalable quality control

58 teen participants enrolled, and 17 underwent interpretable baseline (18)F-fluoride PET imaging before

59 , an area where neural inactivation leads to interpretable behavioral deficits.

60 community challenge establishes biologically interpretable benchmarks, tools and guidelines for molec

61 tion of these genetic association results to interpretable biological mechanisms and models is laggin

62 levels of significance and in providing more interpretable biological models.

63 In spite of myriad advances, recovering interpretable biological signal from data corrupted by t

64 We aim to translate our findings into an interpretable biopsychosocial model that can be applied

65 have high predictive accuracy and be easily interpretable by ageing experts.

66 sistance predictive values, that are readily interpretable by practitioners to inform decision-making

67 n expression was detectable in 25.6% of 8179 interpretable cancers.

68 Amplification was found in 17.4% of 109 interpretable cases for HER2, 6.4% for EGFR, 17.4% for C

69 s of human and social phenomena that provide interpretable causal mechanisms, while often ignoring th

70 egrates these features into a comprehensive, interpretable, cis-regulatory code.

71 To enable this, one needs interpretable classification models (supervised machine

72 Robust and interpretable classifiers with high accuracy are usually

73 ed for clustering can generate intuitive and interpretable clusters when it is tailored to the unique

74 i.e., find reasonably sized and biologically interpretable communities, for the Yeast PPI network but

75 It also leads to more interpretable community structures and allows the quanti

76 model is conceptually simple, constructed of interpretable components, and capable of generating synt

77 robustly decomposes scRNA-seq datasets into interpretable components, thereby facilitating the ident

78 is hindered by the lack of comprehensive yet interpretable computational modeling frameworks.

79 Eighty-one patients enrolled with interpretable computed tomography are reported herein.

80 atly ease adoption of HOGs as a scalable and interpretable concept to relate genes across multiple sp

81 y, studies have uncovered emergence of human interpretable concepts within DCNNs layers trained to id

82 ed their results using quantitative and user-interpretable criteria: detection rate, accuracy, qualit

83 [29%] in the SAVORY registry), 890 [96%] had interpretable CT scans (626 [70%] in the RESOLVE registr

84 patients (92.3%) and 60 vessels (88.2%) had interpretable CTA enabling CT-FFR computation.

85 By contrast, the main source of machine-interpretable data for the materials research community

86 A human-interpretable decision tree shows that phase selection i

87 these challenges by developing DrugCell, an interpretable deep learning model of human cancer cells

88 FA) that leverages temporal measurements and interpretable deep learning models to assess illness sev

89 Here we report an interpretable deep learning strategy that delineates uni

90 linear regression model and the biologically interpretable Deltabeta.

91 se functions while providing physiologically interpretable descriptions of neural computation.

92 Through its interpretable design, HE2RNA provides virtual spatializa

93 ortical parcellations, but show significant, interpretable deviations in improperly developed brains.

94 he image space, we extracted a behaviourally interpretable dimension of emotional valence.

95 inder, a principled approach to deconvolving interpretable discriminative sequence features associate

96 ithout losing the possibility of deriving an interpretable distance measure from the estimated simila

97 the co-expression of pairs of genes, yields interpretable doublet annotations.

98 ssed low dimensional neural code and reveals interpretable dynamics [1], while findings of high dimen

99 ensional Markov process, thereby enabling an interpretable dynamics analysis for a variety of biologi

100 etric family of Gaussian DPPs with a clearly interpretable effect of parametric modulation on the obs

101 can be captured by a fairly low-dimensional, interpretable embedding that generalizes to external beh

102 simony (ie, the need to reduce the number of interpretable end points to control the overall type I e

103 making regularized GLMs more accessible and interpretable, eNetXplorer guides the process to generat

104 ding statistically powerful and biologically interpretable enrichment for complex disease association

105 rocedures can effectively provide clinically interpretable evidence on safety, even with relatively f

106 of surgical quality-improvement initiatives, interpretable evidence to support existing approaches is

107 classifiers are simple functions of directly interpretable experimental parameters with clear physica

108 e changes that will enhance reproducible and interpretable experiments by accounting for metagenomic

109 and provides a mechanistic and biologically interpretable explanation for the temperature dependence

110 or reliable training, scalable inference and interpretable explanation of the DNA repair outcome foll

111 Herein, a locally interpretable explanatory method termed Shapley additive

112 athway annotations to guide the inference of interpretable factors underpinning the heterogeneity.

113 In this paper we propose two interpretable feature types based on Kyoto Encyclopedia

114 xtends upon previous methods for identifying interpretable features in RFs and brings them together u

115 In addition, our assay provides interpretable features that could aid pathological inspe

116 Importantly, SCALE also generates interpretable features that directly link to cell popula

117 ds focus either on predictive performance or interpretable features, we developed a method striking a

118 itions, how many phenotypes are biologically interpretable for predicting gene function, and what exp

119 information and visualizing it in a readily interpretable form.

120 ptive shapes and shading provides a far more interpretable format to recognize visual patterns and in

121 is presenting the data to researchers in an interpretable format.

122 of bisulfite converted DNA in a compact and interpretable format.

123 ase searches that are dependent on acquiring interpretable fragmentation spectra (MS2) of peptide-lig

124 xplore Bayesian networks as a convenient and interpretable framework for the simultaneous modeling of

125 Second, interpretable functional connections arise when the ultr

126 rs of features corresponding to biologically interpretable gene sets.

127 network measures, while also yielding easily interpretable generators.

128 of 60 706 individuals to identify clinically interpretable genes robustly associated with dominant mo

129 ne interactions, and (b) the need for highly interpretable glass-box models.

130 titative high-content imaging data as easily interpretable glyphs, and we illustrate how PhenoPlot ca

131 or global balance measures as well as easily interpretable graphical comparisons.

132 es an approach to generating an accurate and interpretable group-level model for SIB identification,

133 Toward this goal, approaches to make AI "interpretable" have gained attention to enhance the unde

134 hromatin accessibility datasets, based on an interpretable, hierarchical markup language of cell type

135 ps of similar patients revealed a clinically interpretable hierarchy of subgroups characterized by si

136 l exclusivity of FGFR3 and TP53 mutations is interpretable if FGFR3 is mutated first.

137 Interpretable IHC and ISH scores were available in 1,212

138 imitation of TTE is the difficulty obtaining interpretable images due to external and patient-related

139 Results Overall, 239 patients had interpretable images of RV volume.

140 Sixty-seven eyes (91%) had interpretable images, of which 50 (75%) had anomalous mi

141 CXRs were interpretable in 3587 (85%) cases, of which 1935 (54%) w

142 ssful in 103 of the 106 children (97.2%) and interpretable in 99 of these 103 (96.1%).

143 Collected spectra are also searchable and interpretable in both commercial and institutional IR da

144 HSM models are interpretable in familiar biophysical terms at three spa

145 ationally impulsive but are instead directly interpretable in terms of profitability ranking.

146 ials of TB vaccines, which renders them more interpretable in terms of transmission models and transl

147 The method is interpretable in that it generates drug interaction cand

148 inding data acquired contains systematic and interpretable information reflecting the specificity of

149 ces could provide important and biologically interpretable information to identify molecular subgroup

150 as resembling black boxes with limited human-interpretable insight.

151 We expand the range of interpretable isotope effects by assigning this spectral

152 ty-wide, consensus-based, human- and machine-interpretable language for describing phenotypes and the

153 ly we sought maximally correlated, maximally interpretable latent dimensions of brain connectivity an

154 s and the expression of a comprehensive, but interpretable list of transcriptional programs that repr

155 ho underwent an endoscopic procedure and had interpretable liver stiffness measurements and platelet

156 ntations in deeper layers tend to learn more interpretable localist representations, i.e. whole motif

157 tional approach that infers small and easily interpretable logic models of binary input features that

158 ortant step towards practical application of interpretable logic models.

159 nsional model representation (HDMR) to build interpretable low dimensional approximations of the log-

160 Symbolic regression (SR) is an approach of interpretable machine learning for building mathematical

161 thods based on topological data analysis and interpretable machine learning for quantifying both agen

162 d an approach for uncovering MoAs through an interpretable machine learning model of transcriptomics,

163 ntly outperformed in accuracy by other, less-interpretable machine learning models, such as ensemble

164 tion into the sgRNA design, we develop novel interpretable machine learning models, which integrate f

165 hemical profiles of the single cells through interpretable machine learning, facilitating downstream

166 of the model, has increased the interest in interpretable machine learning.

167 information toward biologically informed and interpretable machine learning.

168 of microscopic systems in a quantitative and interpretable manner.

169 ed and unsupervised ML to efficiently create interpretable maps of important features from molecular

170 crobiome Health Index (GMHI), a biologically-interpretable mathematical formula for predicting the li

171 We introduce a predictive, interpretable, matrix-level QC metric, mQC, based on a m

172 Robustness is an easily-interpretable measure of the propensity of a clustering

173 urrent state-of-the-art methods and provides interpretable measures of feature importance.

174 used to guide the selection of biologically interpretable mechanistic forms of the PDE terms which p

175 hematical population modeling owing to their interpretable, mechanistic parameters and amenability to

176 ve been developed using reconstructed, human-interpretable medical images.

177 e mathematical approaches produce physically interpretable membrane shapes, energy estimates for the

178 We introduce DeMaSk, an intuitive and interpretable method based only upon DMS datasets and se

179 , the VarCoPP has been designed to act as an interpretable method that can provide explanations on wh

180 DR3 sequences, using representative, readily interpretable methods for evaluating CDR sequence simila

181 er, the lack of a sensitive, accessible, and interpretable metric of conflict has led researchers to

182 This outcome is a useful and easily interpretable metric to monitor effectiveness of PrEP pr

183 Our approach employed new interpretable metrics that quantify spectral characteris

184 allenges and promising future directions for interpretable ML in genetics and genomics.

185 Here, we discuss the importance of interpretable ML, different strategies for interpreting

186 Given this, we tried to build an interpretable model that mimics the physical layout of s

187 An end-to-end interpretable model that takes full radiographs as input

188 information and presenting to clinicians an interpretable model.

189 regulation using a simple, yet biologically interpretable, model to find the logic by which a set of

190 (TFs) as unobserved, provide a biologically interpretable modelling framework, integrating gene expr

191 ugCell provides a blueprint for constructing interpretable models for predictive medicine.

192 lligence to aid in discovery of accurate and interpretable models of complex natural systems.

193 act geometric structures and not in terms of interpretable models of gene behaviour.

194 We use machine learning to build interpretable models of transcriptional regulation that

195 Importantly, P-Net also provides interpretable models that can be easily visualized to ga

196 to predict fine-grained symptom changes with interpretable models.

197 s, 14 gorillas, and six orangutans, in which interpretable MSY sequence ranges from 2.61 to 3.80 Mb.

198 er demonstrate that revamp results in easily interpretable multi-tissue gene expression associations

199 Further, MARS automatically generates interpretable names for new cell types by probabilistica

200 y Maximization, provides a more biologically interpretable network in our dataset, than that obtainab

201 This protocol will help build more interpretable neuroimaging-based machine-learning models

202 tant patterns then are integrated to produce interpretable niche gradients, ordinations and classific

203 Interpretable OCTA images were obtained in 82% of partic

204 es may not be relevant, and thus expand the 'interpretable 'omics' of single subjects (e.g. personalo

205 Patient genomes are interpretable only in the context of other genomes; howe

206 pes, or molecular targets may not be readily interpretable or integrated.

207 inary Alignment/Map file and produces easily interpretable output.

208 click Express Analysis interface to generate interpretable outputs.

209 od includes fast model fitting that provides interpretable parameter estimates corresponding to how q

210 n alternative modeling approach, based on an interpretable parameterization and driven by careful con

211 enerative models which infer mechanistically interpretable parameters (of computational or physiologi

212 es citation records with merely three easily interpretable parameters: productivity, total impact, an

213 otentially causative of disease, and returns interpretable pathogenicity score distributions on indiv

214 erformance, but also provides a biologically interpretable perspective into the mode of interaction.

215 Interpretable PFTs (188 HIV-infected and 132 HEU partici

216 dditional advantage in that it produces more interpretable posterior probabilities for each variable

217 he proposed algorithms can be used to obtain interpretable prediction rules with high prediction accu

218 e leverage this to train a simple and easily interpretable predictive model that outperforms other ex

219 ading to improved feature selection and more interpretable principal component loadings and potential

220 raged to consider this robust and clinically interpretable procedure as an additional tool for evalua

221 of using curated barcode libraries to obtain interpretable quantitative data and underline the need f

222 pic microimaging and to furnish biologically interpretable, quantitative, and dynamic molecular maps

223 %) were also non-interpretable, that left 44 interpretable radiographs in the study.

224 es, with an emphasis on methods that provide interpretable readouts.

225 e results demonstrate that the GP models are interpretable, recapitulating biological knowledge of gr

226 Providing a compact yet biologically interpretable representation ofDrosophilaexpression patt

227 elopment is the generation of mathematically interpretable representations to predict disease comorbi

228 s guidance will facilitate more accurate and interpretable research that will support the development

229 h expresses interaction energies as a sum of interpretable residue-pair and triplet terms, achieves a

230 49 of the children with interpretable results (49.5%) had GERD according to RI,

231 The method produces easily interpretable results because of its focus on subnetwork

232 Of these, 58 patients displaying interpretable results constituted the study group.

233 mmary, LIRICAL provides accurate, clinically interpretable results for phenotype-driven genomic diagn

234 Accurate and interpretable results for specific hypotheses will be be

235 porate multiple kernel learning, and provide interpretable results for the effects of individual cova

236 stimate in a consistent framework, providing interpretable results that meaningfully deal with enviro

237 This assay generates robust and easily interpretable results that provide direct experimental e

238 These attributes lead to interpretable results with high predictive performance.

239 It produces easily interpretable results, can represent abrupt and gradual

240 In addition to outputting meaningful and interpretable results, we demonstrate in a variety of da

241 obust analytical pipeline to produce readily interpretable results.

242 -gene interactions and yield mechanistically interpretable results.

243 that one can get biologically meaningful and interpretable results.

244 ssignment changed, providing more clinically interpretable results.

245 hers to generate biologically meaningful and interpretable results.

246 d experimental design that will yield clean, interpretable results.

247 e TPOT computation time and may provide more interpretable results.

248 obiome data, but also generates biologically interpretable results.

249 Equally important will be the ethical and interpretable return of results to practicing oncologist

250 joint analysis of V1 and S1 profiles outputs interpretable RNA structure states, while approaches tha

251 ase pairing potential and provides a readily interpretable roadmap to guide functional studies of RNA

252 biome time-series analysis that infers human-interpretable rules linking changes in abundance of clad

253 These models do not learn simple, human-interpretable rules or representations of the world; rat

254 d biases in the data, yielding statistically interpretable scores for the probability of nucleotide m

255 aled by a size-independent and statistically interpretable scoring metric.

256 these data instantly accessible in an easily interpretable, searchable and reusable manner and thus o

257 external world by parsing mixed inputs into interpretable segments.

258 16 to 0.53 mSv), yielding 96.9% (436 of 450) interpretable segments.

259 imulation patterns and provides a simple and interpretable set of computations that can be used to ch

260 provides a robust, reproducible, and highly interpretable single-cell analysis platform that couples

261 h molecular data analytics that can discover interpretable single-subject signals (N-of-1).

262 Both algorithms can yield sparse and interpretable solutions.

263 sly assign signatures, leading to sparse and interpretable solutions.

264 The model produces highly interpretable, spatially-circumscribed topics that enabl

265 is prediction, pathway-level models are more interpretable, stable and parsimonious compared to gene-

266 showing that the results yield powerful and interpretable statistics on the quantities of interest.

267 SemRep is a broad-coverage, interpretable, strong baseline system for extracting sem

268 is of post-implantation variables, the first interpretable study (</=6 months) was used.

269 ecular interactions to find high-confidence, interpretable subnetworks that best explain the data.

270 pproaches can provide more accurate and more interpretable subnetworks.

271 iclustering to identify patient subtypes and interpretable subtype-specific transcript clusters.

272 Furthermore, an intuitive and clinically interpretable summary of treatment efficacy based on thi

273 to EHR to provide physicians with real time (interpretable) support.

274 Interpretable techniques known as white box methods incl

275 chine learning methods, ranging from simpler interpretable techniques to complex (non-linear) "black-

276 We present MITRE, the Microbiome Interpretable Temporal Rule Engine, a supervised machine

277 nctional regions that are significantly more interpretable than more traditional decomposition techni

278 on and yields analysis results that are more interpretable than the existing mCIA.

279 ffect predictions that are more accurate and interpretable than those of alternative tools.

280 some Fisk radiographs (26.7%) were also non-interpretable, that left 44 interpretable radiographs in

281 xible: it generates outcomes that are easily interpretable; the user can set their own outbreak detec

282 oimaging-based machine-learning models to be interpretable, they should (i) be comprehensible to huma

283 eatures inferred by the RBM are biologically interpretable: they are related to structure (residue-re

284 This thereby extracts rational and interpretable thoughts of the agent from its behavior.

285 oscillators while avoiding the need for less interpretable thresholds.

286 mplex data into meaningful concepts that are interpretable to healthcare givers to make use of them.

287 he supervised benchmark methods and provides interpretable transcriptional features in diverse biolog

288 st of both worlds: it grows a single, highly interpretable tree that has the high accuracy of ensembl

289 h a given genetic variant, as a biologically interpretable unit for quantifying the effect size of ci

290 We introduce identifiable and easily interpretable variables that contain all available infor

291 ures, and at the same time allows for easily interpretable visualizations of the most significant dif

292 f gene fusion products and generating easily interpretable visualizations.

293 The ES provides a readily interpretable way to examine the combined effect of many

294 They provide a simple but elegant and interpretable way to model certain kinds of nonlinear re

295 lex structure-performance relationship in an interpretable way, and solve the one-to-many mapping iss

296 ex "omics" data in an interactive and easily interpretable way.

297 dynamics are specified to solve a task in an interpretable way.

298 phores (superposition model) but are readily interpretable within a charge transfer (CT) model.

299 rectly, GG causality estimates alone are not interpretable without examining the component behaviors

300 5 female ET patients investigated, 61 had an interpretable XCIP, and a clonal pattern was observed in