ライフサイエンスコーパス: interscapular

1 ed (epididymal, subcutaneous, perirenal, and interscapular).

2 et increased the thermogenic capacity of the interscapular and aortic brown adipose tissues, whereas

3 e the expression of key thermogenic genes in interscapular and visceral WAT.

4 The norepinephrine content of the interscapular BAT (IBAT) and the number of sympathetic g

5 Using mouse interscapular BAT (iBAT) as an example, we studied the c

6 SNS outflow to, and receive SS inflow from, interscapular BAT (IBAT) in these separate studies sugge

7 nt increase of [(18)F]-FDG-glucose uptake in interscapular BAT (iBAT) of DIOs upon FGF21 administrati

8 ignaling stimulates sympathetically-mediated interscapular BAT (IBAT) thermogenesis.

9 yf5+ epaxial dermomyotome that gives rise to interscapular BAT (iBAT).

10 We surgically removed interscapular BAT (iBAT, which constitutes approximately

11 s to evaluate (18)F-FDG biodistribution into interscapular BAT and major organs.

12 in obese mice, 2) silencing of the Pnpla2 in interscapular BAT causes a brown-to-white phenotypic shi

13 However, whereas interscapular BAT in T3-treated mice showed a 3.0 degree

14 dy temperature, with a 2.5-fold elevation in interscapular BAT mass and lipid storage.

15 at the local administration of AAV8-sgRNA to interscapular BAT of adult mice robustly transduced brow

16 Our findings indicate that the interscapular BAT of Ucp1 knockout mice exhibits mitocho

17 s underlies some of these effects, although, interscapular BAT temperature (T(IBAT)) has not been mea

18 in uncoupling protein 1 (UCP1) expression in interscapular BAT was accompanied by a marked reduction

19 Blood flow of interscapular BAT was assessed in mice (n=64) with CU by

20 of sympathetic ganglion cells projecting to interscapular BAT were 70% greater in the 18 degrees C-r

21 FDG, in percentage injected dose (%ID)/(g of interscapular BAT) x (kg of body weight), was significan

22 male rat gastrocnemius, subcutaneous WAT and interscapular BAT, coupled with neurochemical characteri

23 d dose (%ID) per gram of each radiotracer in interscapular BAT, normalized to blood %ID/g.

24 loss of NPY in sympathetic neurons whitened interscapular BAT, reducing its thermogenic ability and

25 , results in marked increases in the mass of interscapular BAT.

26 f murine visceral and subcutaneous white and interscapular brown adip ocytes.

27 d the changes in transcription that occur in interscapular brown adipocytes during development.

28 Importantly, although the ScaPCs from interscapular brown adipose tissue (BAT) are constitutiv

29 epidydmal and subcutaneous depots but not in interscapular brown adipose tissue (BAT) in mice fed a h

30 n preadipocyte cell line and to increase rat interscapular brown adipose tissue (BAT) mass.

31 tor gamma coactivator-1alpha) were higher in interscapular brown adipose tissue (BAT) of mice receivi

32 ined the response of inguinal WAT (iWAT) and interscapular brown adipose tissue (BAT) to an acute (48

33 t increase in the epididymal fat pad weight, interscapular brown adipose tissue (BAT) weight, and pla

34 tra-abdominal white adipose tissue (WAT) and interscapular brown adipose tissue (BAT), causing decrea

35 We studied interscapular brown adipose tissue (iBAT) activity in wi

36 [(3)H]NE turnover in interscapular brown adipose tissue (IBAT) and retroperit

37 of whole-body glucose uptake identifies the interscapular brown adipose tissue (iBAT) as a primary s

38 and uncoupling protein (UCP1) mRNA levels in interscapular brown adipose tissue (IBAT) from F344 x BN

39 The thermogenic activity of interscapular brown adipose tissue (IBAT) in response to

40 ffect of incremental [ADP] on respiration in interscapular brown adipose tissue (IBAT) mitochondria,

41 gher levels of UCP1 protein were observed in interscapular brown adipose tissue (iBAT) of ppHF dams,

42 Cold exposure triggers neogenesis in classic interscapular brown adipose tissue (iBAT) that involves

43 Energy dissipation through interscapular brown adipose tissue (iBAT) thermogenesis

44 ow markedly increased energy expenditure and interscapular brown adipose tissue (iBAT) thermogenesis

45 The melanocortins (MC) can affect interscapular brown adipose tissue (IBAT) thermogenesis

46 Analyses of interscapular brown adipose tissue (IBAT) thermogenesis

47 trol on thermogenesis in skeletal muscle and interscapular brown adipose tissue (IBAT) was investigat

48 and epididymal white fat pad weights, while interscapular brown adipose tissue (IBAT) weight doubled

49 In interscapular brown adipose tissue (iBAT), cold exposure

50 ndrial biogenesis-regulating proteins in the interscapular brown adipose tissue (IBAT).

51 of UCP2 and UCP3 in white adipose tissue and interscapular brown adipose tissue and in gastrocnemius/

52 However, they have reduced interscapular brown adipose tissue and intra-abdominal f

53 521(-)/(-) embryos exhibit increased mass of interscapular brown adipose tissue and subcutaneous whit

54 take revealed increased glucose clearance in interscapular brown adipose tissue and WAT from trained

55 al fat for white adipocytes and brite cells, interscapular brown adipose tissue for brown adipocytes,

56 In contrast, interscapular brown adipose tissue of AF2KO mice accumul

57 tiinflammatory M2 phenotype and expanded the interscapular brown adipose tissue volume.

58 t, size of gonadal white adipose tissue, and interscapular brown adipose tissue.

59 ympathetic firing rate of nerves innervating interscapular brown adipose tissue.

60 ia regulation of neural circuits innervating interscapular brown adipose tissue.

61 own adipocytes show an age-dependent loss of interscapular brown fat but increased expression of unco

62 equencing to characterize the development of interscapular brown fat in mice.

63 ere preserved even after removal of the main interscapular brown fat pad.

64 r8 knockout mice displayed enlarged but pale interscapular brown fat with decreased expression of gen

65 differences between strains were minimal in interscapular brown fat, large differences occurred in w

66 sistance, and enlargement and "whitening" of interscapular brown fat.

67 mis and epaxial muscle and, unexpectedly, to interscapular brown fat.

68 , perirenal, s.c., and mammary gland) and in interscapular brown fat.

69 stologically and transcriptionally resembles interscapular brown fat.

70 he differences between brown adipocytes from interscapular brown tissue (iBAT) and those induced in w

71 ciency and showed that mice tolerated single interscapular doses of Z-LLF-CHO without unacceptable to

72 Cells transplanted into the interscapular fat pads of isogenic mice formed well defi

73 pancreatic tumor tissues were implanted into interscapular fat pads of NSG mice, and mice were given

74 yonic origin and anatomically located in the interscapular region of mice; and recruitable BAT (rBAT)

75 Skin temperature in the interscapular region of neonates was lower in uncoupling

76 which supplemental heat was provided to the interscapular region using a thermode and in which BAT w

77 000 IEQ/device) at two sites (left thigh and interscapular region) and were explanted at 2, 6, and 12

78 -1.5% and 94.3%+/-5.71% viable beta cells in interscapular site and thigh in autologous recipients an

79 in autologous recipients and 85.6%+/-4.01% (interscapular site) and 74.1%+/-12.05% (thigh) viable be

80 t, but now exhibited pronounced decreases in interscapular temperature and decreased rates of myoclon

81 ased heat production, maintained an elevated interscapular temperature, and maintained baseline level

82 ession of Wnt10b with UCP1 and PGC-1alpha in interscapular tissue from cold-challenged or genetically

83 Interscapular tissue of FABP4-Wnt10b mice has the visual

84 While interscapular tissue of UCP1-Wnt10b mice lacks expressio

85 10b transgenic mice, which express Wnt10b in interscapular tissue, lack functional brown adipose tiss

86 r of brown adipose cells in brown adipose of interscapular tissue.