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1 gnaling pathways in glomerular, tubular, and interstitial cells.
2 valve by Lp(a) and is also secreted by valve interstitial cells.
3 y play a role in the mineralization of valve interstitial cells.
4 plays a role in the mineralization of valve interstitial cells.
5 with a transient decline on P8 primarily in interstitial cells.
6 cells, immune cells, and various classes of interstitial cells.
7 ne TGF-beta signaling between epithelial and interstitial cells.
8 GFRalpha(+) cells are distinct from c-Kit(+) interstitial cells.
9 tissue constructs seeded with porcine valve interstitial cells.
10 ific protein-1-expressing (FSP-1-expressing) interstitial cells.
11 tor IL-13ralpha2 in close proximity to valve interstitial cells.
12 onad that also gives rise to uncharacterised interstitial cells.
13 helium contributes only to non-steroidogenic interstitial cells.
14 s, 10.6% were glomerular cells, and 81% were interstitial cells.
15 ng primarily in CD45-positive leukocytes and interstitial cells.
16 some bronchial epithelial, endothelial, and interstitial cells.
17 gnals to cardiomyocytes, vascular cells, and interstitial cells.
18 ed the effects of Lp(a) and OxPL on valvular interstitial cells.
19 signalling and lysosomal homeostasis within interstitial cells.
20 dence, in the case of heart valves, as valve interstitial cells.
21 ling is activated in both cardiomyocytes and interstitial cells.
22 tedly induced via Rag1-Cre expression in CNS interstitial cells.
23 protein kinase 1) in cultured porcine valve interstitial cells.
24 ctor receptor-alpha positive (PDGFRalpha(+)) interstitial cells.
25 revented H19-induced mineralization of valve interstitial cells.
26 duced renal Epo in a limited number of renal interstitial cells.
27 duction in the number of EPO-producing renal interstitial cells.
28 reased the REPC fraction among Phd2-/- renal interstitial cells.
29 d DCN produced by prematurely differentiated interstitial cells accumulates in the extracellular matr
30 1) to be a mediator of Aldo-induced valvular interstitial cell activation and proteoglycan secretion
31 ation at the neonatal stage and varied valve interstitial cell activation at early and late stages.
32 dothelial injury and a cascade of immune and interstitial cell activation in the kidney lead to AKI.
35 -derived cells to the expanded population of interstitial cells after kidney damage in animals and hu
36 aling is activated in tubular epithelial and interstitial cells after renal injury, and recombinant s
37 -catenin signaling in tubular epithelial and interstitial cells, along with increased expression of m
39 hat reorganization of the vasculature and of interstitial cells also play critical roles in testis co
40 the native thymus, when combined with thymic interstitial cells and a natural decellularised extracel
41 ed expression of COX-2 in WT renal medullary interstitial cells and again the increase in formation o
42 HIF-2/EPO axis in FOXD1 stroma-derived renal interstitial cells and examined the role of individual P
44 rogenesis and osteogenesis of cultured valve interstitial cells and is downregulated in stenotic aort
45 transvalvular pressure can activate valvular interstitial cells and latent paracrine signaling cytoki
46 ) derived from smooth muscle cells, valvular interstitial cells and macrophages as the mediators of c
49 s-attenuating role for Mrc2-expressing renal interstitial cells and suggest the involvement of a lyso
50 ecular, and histological changes of valvular interstitial cells and valvular endothelial cells associ
53 s) produces the acid-secreting copper cells, interstitial cells, and enteroendocrine cells of the sto
54 d by immunohistochemistry within epithelium, interstitial cells, and macrophages in the distal renal
55 67 labeling, rare positive COX-2 staining of interstitial cells, and negative or mild staining for p5
56 ecting duct, proximal tubule, distal tubule, interstitial cells, and rarely glomerular cells followin
57 expression in cultured mouse renal medullary interstitial cells, and Sirt1+/- mice displayed reduced
58 ng osteoblast differentiation in human valve interstitial cells, and that this can be a potential tar
59 orin (DCN) is repressed by FOXD1 in cortical interstitial cells, and we show that compound genetic in
60 r epithelial cells and macrophages and a few interstitial cells are the source of the cytokines and c
61 findings have pointed to the urothelium and interstitial cells as key participants in the transducti
63 ever, UUO induces RGC-32 expression in renal interstitial cells at the early stage of kidney injury,
64 of fibroblast activation, is limited to the interstitial cells at the early stage, and became appare
65 ronic inflammatory disease, and aortic valve interstitial cells (AVIC) play an important role in valv
66 ur aim was to determine whether aortic valve interstitial cells (AVICs) and pulmonary valve interstit
68 derations, development, endothelial cell and interstitial cell biology, extracellular matrix biology,
71 systemic growth from a subset of enterocytes-interstitial cells-by promoting food intake and insulin/
73 progenitor cells (EPCs) and c-Kit(+) cardiac interstitial cells (cCICs) when cultured together sponta
74 vis-kidney junction regions whereas c-Kit(+) interstitial cells (CD117(+) /CD45(-) ) are found predom
76 t collagen- and glycosaminoglycan-expressing interstitial cell clusters, and prevalent ECM gene expre
79 , Sirt1 activation increased renal medullary interstitial cell COX2 expression both in vitro and in v
81 However, conditional deletion of Wnt4 in interstitial cells did not reduce myofibroblast prolifer
83 provide a molecular link between tubular and interstitial cells during CKD progression and identify S
85 titial pericytes, and these FoxD1-derivative interstitial cells expand and differentiate into smooth
87 eased proliferation of endothelial cells and interstitial cells expressing platelet-derived growth fa
88 protective factor for mouse renal medullary interstitial cells following oxidative stress and sugges
90 did not calcify, whereas sheep aortic valve interstitial cells grown on control substrates calcified
93 lar cells, smooth muscle cells, and valvular interstitial cells, have also been shown to exhibit mult
94 ch suggests that impaired bladder Cajal-like interstitial cells (ICCs) are a important component in t
95 rn of expression of beta2-ARs in human valve interstitial cells (ICs) and assess their influence on d
98 and Results- Primary cultures of human valve interstitial cells (ICs) treated for 21 days with osteog
102 alveolar macrophages in lung, and epithelial/interstitial cells in other organs, including the reprod
104 l changes of PV leaflets and passage zero PV interstitial cells in their protein and gene levels.
105 n of 5-HT(2B) receptors on human heart valve interstitial cells in vitro induces a proliferative resp
107 es, including endothelial, smooth muscle and interstitial cells, in the remodelled pulmonary arteriol
108 ther the mutant oncogene is expressed in CNS interstitial cells, including neuronal cells and progeny
110 ight Adamts19 as a novel marker for valvular interstitial cells; inference of gene regulatory network
111 was arbitrarily set at "i2t2": a mononuclear interstitial cell infiltrate present in at least 25% of
112 l segmental glomerulosclerosis together with interstitial cell infiltrates, upregulated gene expressi
113 eration of both tubular epithelial cells and interstitial cells is reduced by NS8593 treatment in UUO
116 However, bronchiolar epithelial cell and interstitial cell labeling was diminished at 40 days (p
117 rogenesis and inflammation in glomerular and interstitial cells, likely as the result of enhanced PPA
119 ditional CE cells and to both supporting and interstitial cell lineages, implying that cells in the C
122 duced osteogenic differentiation of valvular interstitial cells, mediated by OxPL and inhibited with
124 he knee meniscus as a model system, we query interstitial cell migration in the context of migratory
125 ding of the fundamental mechanisms governing interstitial cell migration might lead to interventions
127 hypothesis that Fen may disrupt mitral valve interstitial cell (MVIC) homeostasis through its effects
128 cultured cells and, notably, in mitral valve interstitial cells (MVICs) obtained during mitral valve
129 In addition to scattered endothelial and interstitial cells, Notch-activated (EGFP(+)) cells unex
130 however, ongoing apoptosis of epithelial and interstitial cells occurred in lungs of SFTPC-/- mice, b
132 69I/+) mice than in single-mutant mice, both interstitial cell of Cajal hyperplasia and mast cell hyp
133 ;T669I/+) mice developed gastric and colonic interstitial cell of Cajal hyperplasia as well as cecal
134 The differential conduction pattern in the interstitial cell of Cajal is responsible for the genera
135 ar pathways downstream of KIT, expression of Interstitial Cell of Cajal-like markers, and release of
136 mal endocardial cushions (EC), and activated interstitial cells of adult diseased valves share charac
137 estinal stromal tumors (GIST) are related to interstitial cells of Cajal (ICC) and often contain acti
138 ated because SMC are electrically coupled to interstitial cells of Cajal (ICC) and PDGFRalpha(+) cell
139 be expressed in smooth muscle cells (SMCs), interstitial cells of Cajal (ICC) and platelet-derived g
142 hysiological approaches to determine whether interstitial cells of Cajal (ICC) are present in the gui
158 r activity, contractions and distribution of interstitial cells of Cajal (ICC) in human gastric muscl
161 Maintaining the integrity of networks of interstitial cells of Cajal (ICC) is essential to preser
163 ffecting the vagus, muscle, enteric neurons, interstitial cells of Cajal (ICC) or other cellular comp
166 ver the past two decades has determined that interstitial cells of Cajal (ICC) serve as pacemaker cel
167 nsiderable speculation about the function of interstitial cells of Cajal (ICC) since their discovery
171 ytium, including smooth muscle cells (SMCs), interstitial cells of Cajal (ICC), and cells expressing
172 ytium, including smooth muscle cells (SMCs), interstitial cells of Cajal (ICC), and cells expressing
173 omes from primary smooth muscle cells (SMC), interstitial cells of Cajal (ICC), and PDGFRalpha(+) cel
174 strointestinal (GI) muscles are generated by interstitial cells of Cajal (ICC), and these events acti
175 quantify nerves, S100beta for glia, Kit for interstitial cells of Cajal (ICC), CD45 and CD68 for imm
177 ice prevented GIST development, although the interstitial cells of Cajal (ICC), the cells of origin o
179 from smooth muscle cells, but present in the interstitial cells of Cajal (ICC), the pacemaker cells t
180 ker cells of the gastrointestinal tract, the interstitial cells of Cajal (ICC), where activation trig
181 es inflammatory responses leading to loss of interstitial cells of Cajal (ICC), which generate intest
182 olves neuropathy, myopathy, and depletion of interstitial cells of Cajal (ICC), which may cause dysrh
188 slow waves (SWs) initiated in intramuscular interstitial cells of Cajal (ICC-IM) by activation of Ca
189 slow waves (SWs) initiated in intramuscular interstitial cells of Cajal (ICC-IM) by activation of Ca
191 ion between enteric nerves and intramuscular interstitial cells of Cajal (ICC-IM) in the stomach and
196 or is present in pacemaker cells such as the interstitial cells of Cajal (ICCs) and atypical SMCs tha
197 this hypothesis by quantifying densities of interstitial cells of Cajal (ICCs) and mapping slow-wave
198 e used Ca(2+) imaging to investigate whether interstitial cells of Cajal (ICCs) at these borders gene
199 patially to ETV1(+) cells, which include the interstitial cells of Cajal (ICCs) from which GISTs pres
201 transplantation, murine stem cells (SCs) for interstitial cells of Cajal (ICCs), electrical pacemaker
202 ternatively, intermediate cells, such as the interstitial cells of Cajal (ICCs), might detect nitrerg
205 nteric and submucosal plexus, had functional interstitial cells of Cajal and had an electromechanical
208 At a more basic level, the importance of interstitial cells of Cajal as pacemakers, neuromodulato
210 SMCs), circular smooth muscle cells (CSMCs), interstitial cells of Cajal distributed in the myenteric
211 ce demonstrating a mechanosensitive role for interstitial cells of Cajal in smooth muscle tissues.
213 omach, but like Kit(W/W-v) mice, they lacked interstitial cells of Cajal in the gut and exhibited bil
214 the interactions between myenteric neurons, interstitial cells of Cajal in the myenteric region (ICC
215 autonomous mechanisms restore the numbers of interstitial cells of Cajal that are reduced in the nNOS
216 testinal muscles is generated by specialized interstitial cells of Cajal that produce the patterns of
219 ies that bind to molecules in neurons, glia, interstitial cells of Cajal, and muscularis macrophages.
220 les of W/W(V) mice, which lack intramuscular interstitial cells of Cajal, did not affect membrane dep
222 astrointestinal muscles, and specifically in interstitial cells of Cajal, provides a means of transmi
235 ymal transition and express markers of valve interstitial cells of different valvular layers, demonst
238 showed by immunofluorescence that the target interstitial cells of Wnt7b/canonical Wnt signaling are
239 In response to equibiaxial stretch, valvular interstitial cells on stiff substrates decreased their t
240 ing nodule formation in porcine aortic valve interstitial cells (PAVICs) cultured in osteogenic (OST)
241 ionic conductances in a novel population of interstitial cells (PDGFRalpha(+) cells) in murine bladd
242 +) cells, which include pericytes and PW1(+) interstitial cells (PICs), play a dual role in muscular
243 process, but growing evidence suggests that interstitial cells play an essential role during testis
245 udy highlights the cellular diversity of the interstitial cell population and suggests that complex c
246 ds, suggesting that regulation of the Leydig/interstitial cell population is important for male germ
248 tures were identified in the nephron, kidney interstitial cell populations, vascular endothelium, and
249 ence of gene regulatory networks in valvular interstitial cells positions Adamts19 in a highly discri
252 yofibroblasts (2.8 times decreased), reduced interstitial cell proliferation (2.6 times decreased), b
253 Eln(+/-) mice demonstrated increased valve interstitial cell proliferation at the neonatal stage an
254 terstitial cells (AVICs) and pulmonary valve interstitial cells (PVICs) differ in expression of Toll-
257 Ca(2+) transients were observed in c-Kit(+) interstitial cells, smMHC(+) PDGFRalpha cells and smMHC(
258 nstant throughout postnatal development, but interstitial cell subpopulations undergo changes in gene
259 expression in primary mouse renal medullary interstitial cells substantially reduced cellular resist
260 ts a new decisive immunological role of lung interstitial cells such as SMC in promoting acute pulmon
261 epends on the immunological function of lung interstitial cells such as smooth muscle cells (SMC).
262 esults from 15-PGDH-expressing myofibers and interstitial cells, such as macrophages, within muscle.
263 ily during fetal development in myocytes and interstitial cells suggesting a role for this protein du
264 mediators colocalized primarily to valvular interstitial cells suggesting autocrine/paracrine activa
268 activation in renal tubular epithelia and in interstitial cells that peaked 2-3 days after injury.
269 at line the leaflet surface and the valvular interstitial cells that populate the valve extracellular
270 Vascular Endothelial Growth Factor (VEGF) in interstitial cells, the local overexpression of the corr
271 1 expression, as shown by He et al., enabled interstitial cells to withstand the oxidizing medullary
272 expansion of three distinct cardiac-derived interstitial cell types from human heart tissue, previou
273 iomyocytes (CM), the heart contains numerous interstitial cell types which play key roles in heart re
275 rozygous knock-out of Phd2 in renal cortical interstitial cells using a Pax3-Cre transgene or by homo
276 plays a role in maintaining renal medullary interstitial cell viability in the hypertonic environmen
277 lular matrix (ECM) organization and valvular interstitial cell (VIC) distribution that characterize t
278 ndothelial cells (VEC) regulate aortic valve interstitial cell (VIC) phenotype and matrix calcificati
279 otypic changes occurring in the aortic valve interstitial cells (VICs) during osteogenic differentiat
280 lmark of early CAVD, but culture of valvular interstitial cells (VICs) in biomaterial environments co
283 rix elasticity, we cultured primary valvular interstitial cells (VICs) isolated from porcine aortic v
285 alves affects the biology of aortic valvular interstitial cells (VICs) remains to be elucidated.
286 ganized extracellular matrix (ECM) and valve interstitial cells (VICs) surrounded by an endothelial c
287 fects of TNF-alpha on murine aortic valvular interstitial cells (VICs) within three-dimensional, free
288 trioventricular valve, we focus on the valve interstitial cells (VICs), which confer biomechanical st
290 lular matrix production in cultured valvular interstitial cells was dependent on SMAD2/3 and p38 sign
293 ultured valve tissues, and cultured valvular interstitial cells were obtained from patients with mitr
295 Gremlin is expressed by mature myofibers and interstitial cells, which are separate from BMP4-express
299 rtical white matter neurons, or white matter interstitial cells (WMICs), are found within the subcort
300 euronal population, also termed white matter interstitial cells (WMICs), in the brain of a lesser ape