ライフサイエンスコーパス: intervene

1 ld suggest when and where to therapeutically intervene.

2 ch carriers require intervention and when to intervene.

3 ens unless neutrophils from the blood stream intervened.

4 Notable developments in the intervening 20 years include substantial progress in und

5 get gaps flanking Mu without replicating the intervening 37 kb of Mu, disassembling the stable transp

6 Over the intervening 40 years however a far more complicated pict

7 In the intervening 75 years, the transformation has grown to en

8 For hairpins with two or more intervening A-T, the transient absorption spectra of DPA

9 es and HIV physicians have an opportunity to intervene, addressing both conditions.

10 eutralizing antibodies with the potential to intervene against multiple circulating HIV-1 strains.

11 rty punishment in which dominant individuals intervened against freeloaders, and partner choice.

12 ent work has focused on the evolution of the intervening air layer between droplet and substrate duri

13 ation has been given to the influence of the intervening air-layer thermodynamic state and compositio

14 bound alkynes to pi-allyls in the absence of intervening allenes.

15 E. coli ingestion and emphasize the value of intervening along these pathways.

16 signs of impending pathology early enough to intervene and ameliorate disease in later pregnancy rema

17 me remain unclear, limiting opportunities to intervene and improve people's patience.

18 However, physicians rarely intervene and no trials have been done on the subject.

19 suggesting that they expected the leader to intervene and rectify the wrongdoer's transgression.

20 Previously intervened and intervention-naive children were not mixe

21 mechanisms by which they occur, and means of intervening and preventing them.

22 ls are strategically positioned to diagnose, intervene, and prevent public health threats.

23 and insulating regimes, we detected a robust intervening anomalous metallic state characterized by sa

24 Quality control mechanisms intervene appropriately when defective translation event

25 ion to assess motor deficits in patients and intervene appropriately.

26 arkers will help design clinical trials that intervene at appropriate times.

27 l differences in cell wall stiffness but may intervene at different developmental stages.

28 t mimic stress-activated conditions can also intervene at later stages of the aggregation pathway to

29 wever, combining molecules to simultaneously intervene at multiple regulatory nodes synergistically e

30 ne expression through numerous proteins that intervene at posttranscriptional steps.

31 veral hours post-PPCI, it may be too late to intervene at that time.

32 fective at reducing Abeta plaque burden than intervening at later times (8 months).

33 ry signaling and potential considerations in intervening at the level of interactomes and gene-regula

34 degrees , 25 degrees , and 30 degrees , with intervening ATP binding, phosphate release, and catalyti

35 inolylcarbenes and 1-naphthylnitrene and the intervening aza-benzobicyclo[4.1.0]heptatrienes, aza-ben

36 ssues allows the producer or veterinarian to intervene before the animals' production levels, or even

37 The possibility of intervening before Abeta reaches pathological levels is

38 ale architecture wherein f-actin and drebrin intervene between microtubules and the plasma membrane.

39 uiry into sensorimotor computations that may intervene between MT and LIP.

40 We demonstrate that the SIT via the intervening Bose metal state occurs if the sheet resista

41 e in the peripheral autonomic nervous system intervening both in the parasympathetic and sympathetic

42 e carry a higher membrane potential than the intervening boundary membranes.

43 rol classes tested at the same times without intervening brain training.

44 This included 827 women with an intervening breast cancer and 771 women without one.

45 ces voltage-dependent calcium channel (VDCC)-intervened calcium influx in airway epithelial cells, re

46 on and specification of arteries, veins, and intervening capillaries.

47 g from direct arterial-venous shunts without intervening capillaries.

48 arteries and veins directly connect without intervening capillary nets, increasing the risk of intra

49 transplanted directly into the wound without intervening cell culture using PDGFRalpha, Osterix (OSX)

50 charomyces cerevisiae cells must degrade the intervening cell wall to allow fusion of the partners.

51 5 wk of the research (18)F-FES PET/CT and no intervening change in management.

52 motion comprehension trended toward favoring intervened children.

53 s involving the transport of CsOH through an intervening chloroform layer.

54 These intervening choice feedback signals predicted the subseq

55 cibly measure both size and stability of the intervening chromatin loops, and use it to demonstrate t

56 ncer-promoter interaction by looping out the intervening chromatin.

57 en proximal Alu elements and deletion of the intervening color marker gene, recapitulating the revers

58 ep iterative homologation processes, without intervening column chromatography, to give contiguously

59 ld involve the apolipoprotein E genotype and intervening conditions during trial.

60 he axoneme, the membrane glycocalyx, and the intervening cytoplasm.

61 rough mutual contractile deformations of the intervening cytoskeletal network.

62 nvolvement of two adjacent vertebrae and the intervening disc.

63 Subsequently, we update the reader with intervening discoveries that underpin our current unders

64 ogen bonds, and native contacts separated by intervening disordered regions (through the Wako-Saito-M

65 e mutated Dmd exon23 resulted in excision of intervening DNA and restored the Dmd reading frame in my

66 origin and an IHF-induced looping out of the intervening DNA mediates their interaction.

67 omosome segregation must be executed without intervening DNA replication.

68 nd OL through the formation of a loop by the intervening DNA segment.

69 reated and distant tumors, while sparing the intervening draining lymph node and spleen.

70 n in global child protection sectors, and to intervene early for individual children experiencing dep

71 Intervening early is therefore important.

72 Intervening early with pharmacotherapy is recommended by

73 perimental and computational evidence for an intervening electron donor-acceptor complex, which is ne

74 Instead, stimulation of hunger requires an intervening endocrine step, namely activation of the hyp

75 The pattern of bristles and intervening epithelial cells (ECs) becomes established t

76 for two aggradational phases separated by an intervening erosional phase.

77 nitric acid solution is passed, without any intervening evaporation step.

78 ight the importance of neural activity as an intervening factor between molecular and behavioral proc

79 The comparison accounted for potential intervening factors that may help better understand the

80 es supports the clinical practice of testing intervening family members first when patients are secon

81 ions arranged in an open or closed ring with intervening foci of punctate hypoautofluorescence.

82 lities and therapeutic windows upon which to intervene for enhanced immunotherapy.

83 s, at the time when these adaptive processes intervene for movement planning.

84 t is rapid and acute, making it difficult to intervene for the purpose of evaluating neuroprotective

85 y the curvature of space around matter in an intervening galaxy.

86 sion, and subsequent supersaturation, of the intervening gas layer in low-pressure, humid conditions.

87 etween H19 and H27 is likely mediated by the intervening gating tryptophan through cation-pai interac

88 cient in deleting the approximately 23 kb of intervening genomic sequences.

89 ton transfer: Tyr8 transfers a proton to the intervening Gln50, which then relays a second proton to

90 tides after a second (GPS2) and third (GPS3) intervening GPS in the environmental exposure unit.

91 llergic rhinoconjunctivitis symptoms after 3 intervening GPSs, corresponding to up to 2 years off tre

92 ss in an environmental exposure unit after 1 intervening grass pollen season (GPS1).

93 y the attendees, what we have learned in the intervening half century, and the relevance of their dis

94 lical rotations in the catalytic core via an intervening HAMP-like domain.

95 ose deposited in bioturbated intervals under intervening higher oxygen.

96 effective approach to prevent, evaluate and intervene in a fast, affordable and reliable way, thus e

97 serve as a baseline for future directions to intervene in allergic disease development, progression,

98 s are strongly age-associated, strategies to intervene in aspects of the stem cell aging process may

99 d delivery depth, or how plasma-derived RONS intervene in biological processes.

100 gnaling, there are also new opportunities to intervene in Complement-mediated disease.

101 ntial to developing new therapeutic tools to intervene in demyelinating diseases such as multiple scl

102 constitutes a safe and promising strategy to intervene in disease progression and preserve beta-cell

103 The ability to intervene in disease progression given a person's diseas

104 rogression at a molecular level to precisely intervene in disease progression.

105 ed as an attractive means to therapeutically intervene in disease states.

106 ust pathogen and will enhance our ability to intervene in disease states.

107 or devising endosymbiont-based strategies to intervene in insect immunity or nematode parasitism for

108 e findings could lead to novel approaches to intervene in neurodegenerative diseases in which myelin

109 ard of, and governments may need to actively intervene in nonsustainable lifestyles to achieve emissi

110 ghlight current efforts to pharmacologically intervene in Notch signaling and discuss promising ongoi

111 esity, suggesting that it may be possible to intervene in obesity by targeting the gut microbiota.

112 ecursors can provide clinicians with time to intervene in order to prevent or mitigate secondary brai

113 ntable device-based monitoring ultimately to intervene in patients with AF before they present with c

114 a virus and suggests a possible direction to intervene in poxvirus infection.

115 is essential to understand RAS action and to intervene in RAS-driven diseases.

116 tial for pharmacologically targeting ATF6 to intervene in such diseases.

117 rrogates of natural lipid-linked glycans can intervene in the cell's traditional workflow, indicating

118 We did not intervene in the control schools.

119 tudies into induction of immune tolerance to intervene in the initiation and progression of islet aut

120 ve been identified by which immune cells can intervene in the metastatic cascade, leading to the deve

121 hould be a valid approach to therapeutically intervene in the pathogenesis of macrophage-driven infla

122 hat targeting PTP1B may be a new strategy to intervene in the progression of AD.SIGNIFICANCE STATEMEN

123 dox active aryldiazonium salt is employed to intervene in the terminal respiratory electron flow, aff

124 in part because it is often unclear where to intervene in these cases.

125 is pleotropic activity makes it difficult to intervene in this system without inducing unwanted effec

126 dults expect the leaders of social groups to intervene in within-group transgressions.

127 Therapeutic drug synergism intervened in cancer treatments has been demonstrated to

128 ant to prevent irreversible fibrosis when AF intervenes in a patient with AFL.

129 ant lysin-motif receptor-like kinase MtLYK10 intervenes in recognition of succinoglycan, as might be

130 ogen sulfide is an essential catabolite that intervenes in the pathophysiology of several diseases fr

131 However, it is not known when succinoglycan intervenes in the symbiotic process, and it is not known

132 d the investigation of how energy metabolism intervenes in this process.

133 ersist scarcely explored as targets, despite intervening in a plethora of pathophysiological events i

134 deed, ageing has proved to be modifiable; by intervening in biological systems, such as nutrient sens

135 Experience of intervening in clusters has resulted in best practice gu

136 s ATF6 as a potential therapeutic target for intervening in diverse ischemia-related disorders.

137 important to understanding and intelligently intervening in herpesvirus infections.

138 but also opens up many new possibilities for intervening in networks.

139 efforts could provide a means of selectively intervening in pathogenesis and overcoming MIF-related g

140 lack of evidence of therapeutic efficacy in intervening in patients with asymptomatic disease.

141 t may ultimately be useful in monitoring and intervening in the aging process.

142 ied as high-potential therapeutic candidates intervening in the intracellular inflammation cascade of

143 Targeting specific T cell subtypes and intervening in their function are emerging a critical st

144 rstanding its workings, to say nothing about intervening in them, is among the hardest problems in sc

145 s, and point to potential new approaches for intervening in these processes to treat addiction.

146 Japan: New Zealand Intervening) in the International Court of Justice.

147 2%) of dentists/therapists stated they would intervene, increasing to 74% (95% CI, 56%-86%) with dent

148 data included at least two outbreaks and the intervening inter-epidemic trough during which fadeout o

149 espite presentation of further images in the intervening interval.

150 hereas the remaining 620 were not previously intervened (intervention-naive group).

151 Then, the ferryl centre of compound II intervenes into the unprecedented S-oxygenation of homoc

152 rtion of dentists/therapists said they would intervene invasively (restoratively) on carious lesions

153 [CI], 15%-28%) of dentists/therapists would intervene invasively.

154 ricuspid regurgitation (TR), the decision to intervene is influenced by right ventricular (RV) size a

155 es managers to look for signs of trouble and intervene, is followed by increases in women managers.

156 Here we demonstrate that c-di-GMP also intervenes later in development to control differentiati

157 ular approaches in neuroscience consider the intervening level of cellular and systems neurophysiolog

158 there is less understanding of pathology at intervening levels of organization.

159 y, and if two converging forks stall with no intervening licensed origin-a "double fork stall" (DFS)-

160 ate the influence of peptide orientation and intervening linker length on the peptides' interaction w

161 igomeric assembly domain, and portions of an intervening linker region.

162 -terminal protease domain connected by three intervening linkers.

163 ipants subsequently navigate, as well as for intervening locations along the route, consistent with t

164 brane (TM) helices 3 and 4 (TM3/4) and their intervening loop, we investigated the structural effects

165 ed with a further three short helices within intervening loops, DfsB belongs to a non-enzymatic class

166 the peripheral upper visual field without an intervening lower quadrant representation.

167 r such memory traces are less affected by an intervening masking stimulus presented 0.2 s after the o

168 ve focused solely on the correlation between intervening matrix and genetic differentiation at a sing

169 Overall, quality of intervening matrix was correlated with genetic different

170 , forest amount, configuration, and types of intervening matrix) to investigate how landscape heterog

171 cement learning and motivation, although the intervening mechanisms remain unclear.

172 s of tracers report on the properties of the intervening medium, characterizes viscosity at length-sc

173 nature of these polysaccharides renders the intervening methyltransferases essential for their optim

174 y function/damage markers and accounting for intervening mortality events.

175 Phenology of the intervening moult was indicative of previous reproductiv

176 nd three chitin-binding (C) domains with two intervening mucin-like (M) domains.

177 rized by a split catalytic SET domain and an intervening MYND zinc finger domain, as well as an exten

178 We focused on the long intergenic/intervening ncRNAs (lincRNAs), hidden within the large a

179 ve or TRPV1-resistant, regardless of whether intervening neurons were excitatory or inhibitory.

180 Numerous long intervening noncoding RNAs (lincRNAs) are generated from

181 ed to changes in the aggregate structure and intervening O-alkylations.

182 Investment and leadership at all levels to intervene on the multiple causes and inequities that mig

183 ular health metrics are measured, evaluated, intervened on, and re-evaluated, can serve as a model fo

184 It is also unclear whether intervening on education will affect CVD, in part becaus

185 e this emotion and its downstream effects by intervening on its somatic markers using wearable techno

186 Additionally, intervening on more risk factors may not necessarily res

187 is the change in the outcome resulting from intervening on the risk factor.

188 ture clinical investigations should evaluate intervening on the targets that have emerged from experi

189 up paradigm predict 1) stronger belief in an intervening/ordering god, and 2) increased strength-of-b

190 drivers of population health so that we may intervene, paving the way for healthier populations.

191 cells by a limited basement membrane without intervening pericytes.

192 h cognitive assessment as well as during the intervening period.

193 on at baseline and loss of employment in the intervening period.Measurements and Main Results: Among

194 burst sources, and their propagation through intervening plasma, has limited their use as cosmologica

195 integrin domain of ChlD, particularly if the intervening polyproline linker region is retained.

196 tion requires a conformational change in the intervening polytopic sequence separating loops 1 and 7.

197 32 weeks and at a previous occasion, with no intervening positive culture or previous unfavorable out

198 ioid prescription 90-180 days postop with no intervening procedures or anesthesia.

199 tory organs(4-6) have been investigated, the intervening process of gut tube formation remains relati

200 IV 3% sodium chloride as this is the time to intervene rather than waiting until more severe symptoms

201 e-intergenic fusions through splicing of the intervening region.

202 elices upon binding to TAZ1 and TAZ2 whereas intervening regions of the p53TAD remain flexible.

203 r epistatic gene interactions in the MAT-CEN intervening regions.

204 ere is great need to understand decisions to intervene restoratively and to find implementation inter

205 5% CI, 40%-56%) of dentists/therapists would intervene restoratively.

206 The extent that dentists' thresholds for intervening restoratively have changed with this evidenc

207 The intervening secular (year-to-year) variation in field in

208 tress communication between loci through the intervening segment.

209 entify restenosis and new disease beyond the intervened segments, both of which may jeopardize patenc

210 nearby insertions generate nucleosome-sized intervening segments.

211 Older age, male sex, multiple intervening self-poisoning episodes, higher socioeconomi

212 n arise from chronic pressure erosion of the intervening septal myocardium, leading to left-to-right

213 e internal intron, the resulting alternative intervening sequence being a longer 3'-extended stwintro

214 tituent introns are abutting and the complex intervening sequence can be excised alternatively either

215 logy is required between the donors, and the intervening sequence from the invading molecule is inser

216 or cytosines are 30 base pairs apart and the intervening sequence harbors several positionally conser

217 lization signal (PY-NLS), which has a unique intervening sequence in huntingtin.

218 e orthologous transcript, in which a complex intervening sequence including the stwintron and neigbou

219 intron (intron-1) evolved from this complex intervening sequence of nested canonical introns found e

220 ox 1 (HMGB1) protein as an interactor of the intervening sequence within the PY-NLS.

221 d via NHEJ, which results in deletion of the intervening sequence.

222 Such intervening sequences can constitute complex introns exc

223 position is occupied by one of three complex intervening sequences consistent of differently nested U

224 ng the UBE2T AluYa5 elements and neighboring intervening sequences flanked by fluorescent reporter ge

225 Five of these snoRNAs interact with the intervening sequences of rRNA precursor, whereas the oth

226 Split eukaryotic genes contain intervening sequences or introns disrupting protein-codi

227 The presence of intervening sequences, termed introns, is a defining cha

228 Stwintrons are complex intervening sequences, where an 'internal' intron interr

229 f distant loci results in the removal of the intervening sequences.

230 s of nuclear integration of the adjacent and intervening sequences.

231 This update incorporates changes over the intervening seven database releases.

232 preceding Habituation night (night 1) and an intervening Sham night (night 3).

233 h the imposed perturbations or to explicitly intervene so as to minimize the influence of the perturb

234 crystallographic alignment, expulsion of the intervening solvent and particle coalescence are enabled

235 ern while later neurons differentiate in the intervening space to eventually produce continuous colum

236 lcified corneal lenses that are separated by intervening spaces containing eumelanin pigment.

237 n with DIY kits is the simplification of the intervening steps going from basic design to fabrication

238 ic coldspot was also found in the form of an intervening strip stretching from the posterior OFC thro

239 deflection of their light by the gravity of intervening structures-and estimating the corresponding

240 discharged prior to 28-days post decision to intervene surgically.

241 While the presence of an intervening tBu group is found to be optimal for maximum

242 es show an alkylation mechanism involving an intervening tetramer-monomer pre-equilibrium followed by

243 xygenase (15-LOX) is a promising strategy to intervene the arachidonic acid (AA) metabolite network a

244 appreciation of features indicating when to intervene therapeutically.

245 lar senescence as an emerging opportunity to intervene through senolytic and senomorphic therapies in

246 ing communities), using systems science, and intervening through combinations of individual, family,

247 In the intervening time, there has been an ever-growing list of

248 The intervening times represent substantially drier phases,

249 much less attention has been focused on the intervening tissue, articular calcified cartilage (ACC)

250 No injury was found on the bladder wall or intervening tissue.

251 r basket protein Nup60 and analyzed how they intervene to control the plasticity of the NPC.

252 This, in turn, limits our ability to intervene to level the playing field.

253 us represents a logical platform in which to intervene to prevent immune escape.

254 reatments have been proven, opportunities to intervene to prevent progressive disease, founded in a t

255 le changes in behaviour that may allow us to intervene to provide pain-relief.

256 r liver disease, creating the opportunity to intervene to reduce liver-related mortality and morbidit

257 These new insights offer opportunities to intervene to support more adaptive development than befo

258 urrently, there are only limited therapeutic intervenes to offer patients diagnosed with pulmonary fi

259 gly, pediatric health care organizations are intervening to address family social adversity.

260 may be a uniquely important time period for intervening to prevent and reduce risk of PTSD.

261 e of a therapeutic window of opportunity for intervening to promote recovery, even in those regions n

262 re repeated within 2 d of each other with no intervening treatment.

263 formation of RNA secondary structure in the intervening unbound regions.

264 tween an exposure and an outcome which, when intervened upon, will block (some or all of) the causal

265 f glucose values), and only 1% were actively intervened upon.

266 ular, we speculate that body image may be an intervening variable mediating the relationship between

267 around the light-emitting diffuser, with no intervening viable parenchymal cells.

268 t baseline MA yet developed MA by 18 months, intervening visits were assessed to determine the first

269 to say that they intuitively recognised when intervening was likely to alleviate calling out.

270 al alignment and systematically decreases as intervening water density increases.

271 ree energy wells distinguished by numbers of intervening water layers, which reach a minimum when ali

272 force spectroscopy, highlighting the role of intervening water molecules.

273 60(o) periodicity, revealing the key role of intervening water structuring as a basis to generate the

274 RD is stacked a top the TMD, separated by an intervening wedge-like linker domain.

275 d infants (n = 120) would expect a leader to intervene when observing a within-group fairness transgr

276 in size and topographical complexity (e.g., intervening white matter tracts) in larger brains may se

277 the therapeutic potential of these drugs to intervene with inflammatory disorders.

278 l edema (nausea, vomiting, and headache) and intervene with IV 3% sodium chloride as this is the time

279 al neurodegenerative states, and potentially intervene with neuroprotective therapy.

280 reduce incarceration itself and effectively intervene with prisoners to screen, diagnose, and treat

281 t least middle childhood without the need to intervene with the child directly.

282 Subjects were instructed either to not intervene with the imposed perturbations or to explicitl

283 metic neuron, with the capacity to precisely intervene with the underlying malfunctioning signalling

284 which patients best benefit from and when to intervene with TPIAT, current limitations of the surgica

285 llular inhibitor and point to new methods to intervene with viral cyclins.

286 slices and cultured pericytes were used, and intervened with endothelial nitric oxide synthase (eNOS)

287 by hepatic BA synthesis, C57BL/6J mice were intervened with GW4064/resin to decrease/increase hepati

288 We intervened with the IL-33 cascade and sought to dissect

289 tal myelination and suggest the potential of intervening with an oligodendroglial HIFalpha-mediated s

290 n carcinogens (e.g., tobacco or asbestos) to intervening with anticarcinogenic strategies (behavioral

291 n carcinogens (e.g., tobacco or asbestos) to intervening with anticarcinogenic strategies (behavioral

292 Our results demonstrate that intervening with endogenous ADAM sheddase modulatory mec

293 inhibiting reactive oxygen species (ROS) or intervening with ROS-dependent JNK activation that leads

294 Identifying and intervening with socially isolated adults could improve

295 ligases represent the most selective way to intervene within this physiologically important system.

296 In the intervening years it became clear that both viruses were

297 ered by adult stem cells 4 years ago.(1) The intervening years since that first review has witnessed

298 trifluoromethyl radical to an allene; in the intervening years, both the chemistry of allenes and the

299 During the intervening years, resuscitation science has advanced co

300 extended enrichment in adoptive homes in the intervening years.