ライフサイエンスコーパス: intestinal absorption

1 f current knowledge on the regulation of its intestinal absorption.

2 ility and high deacylation of NAC during the intestinal absorption.

3 istical pattern recognition model of passive intestinal absorption.

4 generally results from a chronic increase in intestinal absorption.

5 se hydrolyzes dietary folates prior to their intestinal absorption.

6 s to solubilize lipophilic drugs and enhance intestinal absorption.

7 proteins critical for nutrient digestion and intestinal absorption.

8 on, is degraded by gut bacteria reducing its intestinal absorption.

9 64 Cu uptake reflect the effect of drugs on intestinal absorption.

10 w a high level of safety and strong skin and intestinal absorption.

11 ave not been rigorously tested to understand intestinal absorption.

12 and clearance in plasma indicative of small intestinal absorption.

13 alternatives might be based on reducing its intestinal absorption.

14 of dietary energy, and enhanced capacity for intestinal absorption.

15 he inhibitory threshold values for Ca and Zn intestinal absorption.

16 ys an important role in the process of small intestinal absorption.

17 facilitate the release of metal ions during intestinal absorption.

18 n the colon, largely avoiding proximal small intestinal absorption.

19 en transformed back to the active drug after intestinal absorption.

20 sphate imbalance in mice with reduced active intestinal absorption.

21 y play a role in the regulation of vitamin A intestinal absorption.

22 e pharmacokinetic properties, including high intestinal absorption, acceptable solubility, and low pr

23 Intestinal absorption and biliary excretion of cholester

24 lity to cholesterol gallstones by decreasing intestinal absorption and biliary secretion of cholester

25 Bile acids are required for intestinal absorption and biliary solubilization of chol

26 udy the role of this transporter in limiting intestinal absorption and brain penetration of substrate

27 e in drug development is the optimization of intestinal absorption and cellular uptake.

28 ecessive disorder characterized by increased intestinal absorption and decreased biliary excretion of

29 mmendations are based on the balance between intestinal absorption and endogenous losses, we have stu

30 act the host's energy balance, their role in intestinal absorption and extraintestinal metabolism of

31 inhibitors were tested in in vitro models of intestinal absorption and found to have low absorption p

32 nd cholelithogenesis, possibly by decreasing intestinal absorption and hepatic bioavailability.

33 Mn homeostasis is tightly regulated via intestinal absorption and hepatobiliary and intestinal e

34 While increased intestinal absorption and higher FGF23 can trigger the h

35 recessive disorder characterized by impaired intestinal absorption and impaired transport of folates

36 nsulin are typically designed to improve its intestinal absorption and increase its blood bioavailabi

37 we show that GF versus SPF mice have reduced intestinal absorption and increased fecal excretion of c

38 Heme can also be acquired by intestinal absorption and intercellular transport.

39 oestradiol (E2) and progesterone (P) affect intestinal absorption and lymphatic transport of dietary

40 nding cassette (ABC) transporters that limit intestinal absorption and promote biliary excretion of n

41 Intestinal absorption and renal reabsorption of phosphat

42 nd salt absorption caused by an imbalance in intestinal absorption and secretion.

43 Rates of intestinal absorption and surface hydrolysis are determi

44 determined the effects of PEDV infection on intestinal absorption and the expression of genes for nu

45 erivatives that compete with cholesterol for intestinal absorption and thereby lower serum cholestero

46 ABCG5 and ABCG8 normally cooperate to limit intestinal absorption and to promote biliary excretion o

47 ) profiles of drug candidates, in particular intestinal absorption and transport across the blood-bra

48 on their potential applications in enhancing intestinal absorption and treating inflammatory bowel il

49 sity, which would necessitate an increase in intestinal absorption and/or renal reabsorption of calci

50 s controlled mainly by endogenous synthesis, intestinal absorption, and hepatic excretion.

51 ts found enrichment of genes associated with intestinal absorption, and lipid metabolism, localizatio

52 Models intended to predict intestinal absorption are an essential part of the drug

53 ne, phytofluene, lycopene and beta-carotene) intestinal absorption are still only partly understood.

54 have multiple goals, assessing and enabling intestinal absorption at efficacious doses being one of

55 The aim of this study was to assess intestinal absorption at the time of weaning from parent

56 ry perception, autonomous functions, rate of intestinal absorption, behavior, including cognition and

57 increase in plasma biomarkers of cholesterol intestinal absorption (beta-sitosterol, campesterol, cho

58 intake via eight food types and inhalation, intestinal absorption, biliary excretion, and plastic-as

59 Intestinal absorption, biliary excretion, and urinary ex

60 r gastrointestinal tract was used to compare intestinal absorption/bioaccessibility of blueberry anth

61 iles showed essentially identical effects on intestinal absorption but with lower fecal cholesterol e

62 The prodrug clopidogrel requires intestinal absorption by the efflux pump P-glycoprotein

63 To limit intestinal absorption, C7-sulfated analogues designed to

64 a new concept of "slow vs fast fat," whereby intestinal absorption can be modulated by structuring di

65 After intestinal absorption, circulating genistein and daidzei

66 currence at the sn-2 position allows optimal intestinal absorption conditions.

67 or predictive performance against this human intestinal absorption dataset.

68 he release of carotenoids made available for intestinal absorption depends on carotenoid type and can

69 Upon their intestinal absorption, dietary sugars and a-dicarbonyl c

70 Upon their intestinal absorption, dietary sugars and alpha-dicarbon

71 e physicochemical properties at the point of intestinal absorption due to the changing chemical envir

72 ses, but these bioactive components have low intestinal absorption due to their hydrophobic nature.

73 calcium demand was met by increased maternal intestinal absorption; early breast-milk calcium was pro

74 ansporter, plays a major role in determining intestinal absorption efficiency and hepatic secretion r

75 microbial metabolites but also by affecting intestinal absorption/excretion of host-produced metabol

76 echniques, we show that an accurate model of intestinal absorption for a set of drugs can be construc

77 The low rates of intestinal absorption found in anaesthetised animals may

78 While blocking intestinal absorption has been suggested as a therapeuti

79 Studies on vitamin A intestinal absorption have shown the existence of a rece

80 These findings confirmed efficient intestinal absorption, hepatic extraction, and biliary s

81 idation positively correlated with increased intestinal absorption in both the presence and absence o

82 ns of beta-carotene and canthaxanthin during intestinal absorption in humans.

83 eptide (GLP)-2 analogue developed to improve intestinal absorption in patients with short bowel syndr

84 zation, and enabling accurate predictions of intestinal absorption in the complex bRo5 domain.

85 Improvements in de novo synthesis and intestinal absorption increase glutamine availability ov

86 Hypercalciuria can result from enhanced intestinal absorption, increased bone resorption, or alt

87 Intestinal absorption is an important contributor to sys

88 In mice lacking functional KCNQ1, impaired intestinal absorption is associated with reduced serum v

89 ffect of both systems acting together during intestinal absorption is difficult to ascertain.

90 Vitamin K1 (phylloquinone) intestinal absorption is thought to be mediated by a car

91 Although many models exist for capturing intestinal absorption, many questions still exist around

92 etary iron and elucidation of its pathway of intestinal absorption may lead to the development of imp

93 out overt diarrhea, have profound effects on intestinal absorption, nutrition, and childhood developm

94 ues examined, indicating that no appreciable intestinal absorption occurred.

95 ng mechanisms involved, the effects of NT on intestinal absorption of (3)H-D-glucose, (3)H-leucine, (

96 These values were compared to intestinal absorption of (59)Fe, which was significantly

97 By using the culture system to analyse the intestinal absorption of 2,930 formulations of the pepti

98 impact of delayed enteral nutrition on small intestinal absorption of 3-O-methyl-glucose.

99 In the stressed mice, intestinal absorption of [(14)C]cholesterol was signific

100 effective than taurocholate in promoting the intestinal absorption of a range of drugs, showing that

101 erplasia of the intestine after VSG, but the intestinal absorption of alimentary glucose was reduced

102 cate that Slc10a2 is essential for efficient intestinal absorption of bile acids and that alternative

103 Intestinal absorption of bile acids depends on a sodium-

104 ick C1-like 1 (NPC1L1) plays a major role in intestinal absorption of biliary cholesterol, vitamin E

105 ol carriers, which may in turn influence the intestinal absorption of biliary cholesterol.

106 The intestinal absorption of bioactive compounds from SAE an

107 ot completely understood, but alterations in intestinal absorption of calcium are not thought to be i

108 c array detection enabled us to quantify the intestinal absorption of carotenoids ingested from a sin

109 mg/rat over 8 h, pyran diol 3 inhibited the intestinal absorption of cholesterol by 71% in rats.

110 We blocked intestinal absorption of cholesterol in milk fed to newb

111 similar to cholesterol and partially inhibit intestinal absorption of cholesterol, although their imp

112 sterol esterase is responsible for mediating intestinal absorption of cholesteryl esters but does not

113 objective was to measure total reduction in intestinal absorption of combustible energy after RYGB a

114 Thus, zinc prevents the intestinal absorption of copper.

115 in nitrogen supply to the body by mediating intestinal absorption of di- and tripeptides.

116 s combination with inhibitors that block the intestinal absorption of dietary and biliary cholesterol

117 nts of plasma cholesterol and phospholipids, intestinal absorption of dietary fat and cholesterol, an

118 polyglucosamine biopolymer (BP) shifting the intestinal absorption of dietary fats.

119 Molecular defects in the intestinal absorption of dietary folates that precipitat

120 esence of the H475Y GCPII allele impairs the intestinal absorption of dietary folates, resulting in r

121 principal folate transporter involved in the intestinal absorption of dietary folates.

122 In hereditary hemochromatosis (HH), intestinal absorption of dietary iron is increased, lead

123 gical route to recycle bile salts and ensure intestinal absorption of dietary lipids.

124 ntrols intestinal epithelium homeostasis and intestinal absorption of dietary lipids.

125 Radiotracer studies reveal impaired intestinal absorption of dietary Mn in Slc39a8-IEC KO mi

126 Net intestinal absorption of dietary oxalate results from pa

127 Dietary intake and intestinal absorption of fat, protein, carbohydrate, and

128 obese than controls; they also had increased intestinal absorption of fatty acids and decreased energ

129 he acidic pH optimum for PCFT is relevant to intestinal absorption of folates and could afford a mean

130 transport in many tissues, most notably the intestinal absorption of folates, in terms of pH depende

131 r CEL include the direct facilitation of the intestinal absorption of free cholesterol and the modifi

132 The intestinal absorption of fructose is carried out by the

133 and the GLUT2/GLUT5 inhibitor can reduce the intestinal absorption of fructose to combat the harmful

134 (PE), influence the enzymatic stability and intestinal absorption of glucagon-like peptide-1(GLP-1)

135 , Australia) with 20 MBq Tc-suphur colloid), intestinal absorption of glucose (3 g of 3-O-methyl-gluc

136 ty bile-acid-receptor agonist, increased the intestinal absorption of insulin, polarized intestinal m

137 However, poor intestinal absorption of intact proteins is a major chal

138 ar weight multiligand receptor that mediates intestinal absorption of intrinsic factor-cobalamin and

139 ew, we focus on the key proteins involved in intestinal absorption of iron, zinc, and copper.

140 isoflavone glycosides, and the mechanism of intestinal absorption of isoflavones in humans is unclea

141 tribute to hepatocellular uptake but also to intestinal absorption of its substrates.

142 With rhGH, the intestinal absorption of leucine and glutamine increased

143 glucagon-like peptide-2 (GLP-2) facilitates intestinal absorption of lipids, but its role in chylomi

144 d composition of cow-ghee and edible oils on intestinal absorption of lutein in mice.

145 been thought to be caused by a defect in the intestinal absorption of magnesium, rather than by abnor

146 The intestinal absorption of many nutrients and drug molecul

147 ss I-related Fc receptor, FcRn, mediates the intestinal absorption of maternal IgG in neonatal rodent

148 Intestinal absorption of mercury is influenced by intera

149 Direct intestinal absorption of nanoFe(3+) was investigated usi

150 Mucosal atrophy induced by FM reduces total intestinal absorption of nutrients, but nutrient absorpt

151 tion of vitamin D(3) may allow modulation of intestinal absorption of OATP1A2 transport substrates.

152 the development of mucosal vaccines and the intestinal absorption of oral biologics.

153 The role of SR-BI in the intestinal absorption of other dietary lipids, including

154 as a major constitutive role in limiting net intestinal absorption of oxalate, thereby preventing hyp

155 results describing the bioaccessibility and intestinal absorption of phenolic compounds from strawbe

156 The intestinal absorption of PHIP-M1 is comparable with that

157 Intestinal absorption of phosphate is stimulated by 1,25

158 earance, 3.3 ml/min per kg), the average net intestinal absorption of phosphate over all balance peri

159 earance, 4.0 ml/min per kg), the average net intestinal absorption of phosphate over all balance peri

160 Intestinal absorption of phosphate proceeds via an activ

161 gulation of the mechanism(s) responsible for intestinal absorption of Pi is missing.

162 ter is assumed to mediate the bulk of active intestinal absorption of Pi.

163 h the hypothesis that ezetimibe inhibits the intestinal absorption of plant sterols as well as choles

164 After oral administration (15 mg/kg), intestinal absorption of rosuvastatin was not impaired i

165 nce is maintained primarily by regulation of intestinal absorption of the metal from the diet.

166 rotonin through three mechanisms: diminished intestinal absorption of the serotonin precursor tryptop

167 tiligand endocytic receptor critical for the intestinal absorption of vitamin B12 and renal protein r

168 ion of vitamin D(3) (cholecalciferol) or the intestinal absorption of vitamin D(2) (ergocalciferol).

169 gs revealed that this analogue also promoted intestinal absorption of water and electrolytes during c

170 There is now a general consensus that the intestinal absorption of water-insoluble, dietary lipids

171 n of knowledge has also covered the field of intestinal absorption of water-soluble vitamins and is t

172 derstanding the mechanisms and regulation of intestinal absorption of water-soluble vitamins from the

173 hat the hZIP4 transporter is responsible for intestinal absorption of zinc.

174 lease during digestion) and bioavailability (intestinal absorption) of caffeine in coffee, teas, soft

175 icrobiome effect on prediabetes by affecting intestinal absorption or excretion of host compounds and

176 and ileum and was not secondary to impaired intestinal absorption or hepatic biosynthesis of DHA.

177 r and molecular mechanisms and regulation of intestinal absorption processes of vitamins.

178 This study evaluated the intestinal absorption rate in children with SBS, focusin

179 This leads to the conclusion that the intestinal absorption rate of the two resveratrol oligom

180 Intestinal absorption rate was assessed by a stool balan

181 In addition, the relation between intestinal absorption rate, citrulline concentration, an

182 s is maintained through coordination between intestinal absorption, renal reabsorption, and bone remo

183 fated, and molybdate, which inhibits sulfate intestinal absorption, renal reabsorption, and sulfate i

184 tamin C (ascorbate) are tightly regulated by intestinal absorption, tissue accumulation, and renal re

185 chemistry of copper, including food sources, intestinal absorption, transport, tissue distribution, a

186 stion model for preterm infants coupled with intestinal absorption using Caco-2/TC7 cells.

187 lacyclovir is attributed to carrier-mediated intestinal absorption, via the hPEPT1 peptide transporte

188 ation, and choleretic activity were defined; intestinal absorption was assessed by jejunal or ileal p

189 Intestinal absorption was higher in the SRSB group for t

190 e accumulation was nearly abolished, whereas intestinal absorption was marginally affected.

191 te these borderlines in the clinical setting.Intestinal absorption was measured from April 2003 to Ma

192 etween 24-hour uP and fractional or absolute intestinal absorption was not evident.

193 ill exceed a carbohydrate load threshold for intestinal absorption, which may limit their usefulness

194 sometimes to an even greater extent than did intestinal absorption, yielding no net reduction in phos