ライフサイエンスコーパス: intraarticular

1 Of 31 SI joint injections, 30 (97%) were intraarticular.

2 target error, and whether the injection was intraarticular.

3 lar (65% in paediatric patients) and 44% had intraarticular (69% in paediatric patients) osteoid-oste

4 ible isoforms of NO synthase (NOS), prevents intraarticular accumulation of leukocytes, joint swellin

5 F-kappaB by either proteasomal inhibitors or intraarticular adenoviral gene transfer of super-repress

6 MR imaging was performed before and after intraarticular administration of contrast material.

7 Eight arthrograms were obtained with intraarticular administration of gadolinium solution and

8 elbow specimens were imaged with and without intraarticular administration of gadolinium-containing s

9 MR imaging with intraarticular administration of gadopentetate dimeglumi

10 tion, and fat-suppressed T1-weighted SE with intraarticular administration of gadopentetate dimeglumi

11 In vivo, intraarticular administration of microparticles in rats

12 Further, intraarticular administration of miR-204-expressing aden

13 Intraarticular administration of NF-kB decoys prevented

14 stration of gadolinium solution and two with intraarticular administration of normal saline.

15 Intraarticular administration of sCD59-APT542 markedly a

16 hritis before and after joint aspiration and intraarticular administration of steroids.

17 We found that following intraarticular administration ribozymes were taken up by

18 ing soft tissues that can occur in athletes: intraarticular and extraarticular hip impingement syndro

19 The MR appearances of all intraarticular and periarticular structures were analyze

20 o C57BL/6 mice, MRL/MpJ mice had less severe intraarticular and systemic inflammation following joint

21 The use of an intraarticular anesthetic significantly reduces periproc

22 nograms were positive in 39 and did not show intraarticular bodies in 22.

23 effusion, presence of subchondral cysts, or intraarticular bodies indicate absence of infection.

24 n, and erosion were seen in both groups, but intraarticular bodies were more common in noninfected jo

25 is an accurate method for identification of intraarticular bodies.

26 sociation with instability, labral tear, and intraarticular bodies.

27 maging technique for detection of individual intraarticular bodies.

28 ced MR arthrography improve detectability of intraarticular bodies.

29 Three patients had an intraarticular body.

30 Furthermore, intraarticular CFA-induced ipsilateral mechanical hypera

31 ne male volunteer with a history of previous intraarticular chondroid fragments were calculated by us

32 Three intraarticular collections were included.

33 This study determined, using the intraarticular complete Freund adjuvant arthritis mice m

34 In 32 of the 100 patients, intraarticular contrast material was useful in demonstra

35 Background Intraarticular corticosteroid (IACS) injections are freq

36 drugs (NSAIDs) only, NSAID trial followed by intraarticular corticosteroid injection (IACI) if arthri

37 ith symptomatic TMJ arthritis improved after intraarticular corticosteroid injection.

38 me after 52 weeks of early intervention with intraarticular corticosteroid injections followed by sul

39 e either methotrexate alone (MTX) or MTX and intraarticular corticosteroids (MTX + IAST) into all joi

40 From baseline to week 4, intraarticular corticosteroids appear to be relatively m

41 Intraarticular corticosteroids are an effective treatmen

42 Patients treated with EI using intraarticular corticosteroids followed by sulfasalazine

43 ntibody formation (P < 0.05), decreased Th17 intraarticular cytokine expression (P < 0.01 for interle

44 evaluate its therapeutic efficacy following intraarticular delivery in a rat model of osteoarthritis

45 injury at specific time points, we show that intraarticular delivery of a peptidic nanoparticle compl

46 This trial was designed to evaluate intraarticular delivery of a tumor necrosis factor alpha

47 inflammatory microenvironment suggests that intraarticular delivery of IL-1Ra and/or TNF mAb may be

48 Our results suggest that direct, local intraarticular delivery of the vIL-10 gene may have poly

49 the presence of bioactive peptides following intraarticular delivery.

50 ams for a retear was abnormal tracking of an intraarticular dilute gadolinium-based contrast material

51 MR arthrography depicted best the intraarticular disk and four of five perforations and de

52 or to T1-weighted images in depiction of the intraarticular disk.

53 hy allows delineation of perforations of the intraarticular disk.

54 R arthrography enhances visualization of the intraarticular elements.

55 Prolonged intraarticular exposure to TGF beta has been shown to ca

56 Intraarticular expression of vIL-10 significantly reduce

57 FIX(-/-) mice receiving intraarticular FIX protein were protected from synovitis

58 The presence of intraarticular fluid and performance of saline-enhanced

59 A model of a closed intraarticular fracture in C57BL/6 mice that progresses

60 ice in each group were subjected to a closed intraarticular fracture of the left knee.

61 antly increased the severity of OA following intraarticular fracture.

62 protected from posttraumatic arthritis after intraarticular fracture.

63 d treatment of posttraumatic arthritis after intraarticular fracture.

64 Intraarticular fractures were created in MRL/MpJ mice an

65 Intraarticular fractures were successfully created in al

66 itis is a frequent long-term complication of intraarticular fractures.

67 protected from posttraumatic arthritis after intraarticular fractures.

68 T1-weighted spin-echo (intraarticular gadolinium) or T2-weighted gradient-echo

69 Direct, intraarticular, gadolinium arthrography of the shoulder

70 Intraarticular gene therapy to inhibit IKKbeta activity

71 Intraarticular gene transfer of IKKbeta-dn significantly

72 Intraarticular gene transfer of IKKbeta-wt into the join

73 Intraarticular gene transfer was limited by an adenovira

74 lity at 1 year than patients who received an intraarticular glucocorticoid injection.

75 ctory to standard treatments after failing 2 intraarticular glucocorticoid injections were included.

76 ugs, such as methotrexate, sulfasalazine and intraarticular glucocorticoids, still maintain an import

77 Here multiple washouts were used to measure intraarticular hyaluronan mass and secretion rate in rab

78 Randomized trials that reported effects of intraarticular hyaluronic acid versus corticosteroids on

79 o be relatively more effective for pain than intraarticular hyaluronic acid.

80 Rabbits were treated with intraarticular (i.a.) injections of caspase inhibitors 3

81 pharmacologic efficacy of systemic Scl-Ab or intraarticular (IA) delivery of a sclerostin antibody-Fa

82 he time of arthritis induction with a single intraarticular (IA) dose of the membrane-targeting regul

83 l joint space reveals the brief systemic and intraarticular (IA) half-lives of relaxin-2: 0.96 h and

84 -knockout mice, inflammation was induced via intraarticular (IA) injection of Freund's complete adjuv

85 lar if disease was polyarticular (n = 53) or intraarticular if patients had <5 synovitic joints (n =

86 In addition, no adverse effects following intraarticular IGF-1 gene delivery were observed.

87 C activation appears to play a major role in intraarticular IL-8 generation and in neutrophil recruit

88 ice was attenuated by AP-18 (administered by intraarticular injection 22 hours after the administrati

89 d cartilage from the articular surface after intraarticular injection and from both the articular sur

90 buffered saline vehicle was administered by intraarticular injection for 4 weeks, with dosing interv

91 After intraarticular injection in rat knees, HB-IGF-1 was reta

92 Our findings indicate that after intraarticular injection in rats, HB-IGF-1 is specifical

93 Intraarticular injection of 0.03% carrageenan into rat k

94 dditionally, rats were killed 48 hours after intraarticular injection of Ad.IKKbeta-wt or Ad.GFP for

95 Intraarticular injection of AdIGF-1 resulted in a mean o

96 ethysmometry and histologic assessment after intraarticular injection of an adenoviral construct enco

97 abbits with and without damage introduced by intraarticular injection of chymopapain (CP).

98 cute joint injury was induced in 4 joints by intraarticular injection of chymopapain.

99 Our findings indicate that a single intraarticular injection of concentrated lubricin follow

100 MR arthrography with direct intraarticular injection of contrast material can help i

101 ed MR imaging and with MR arthrography after intraarticular injection of dilute contrast material wit

102 ateral intraplantar injection of TNFalpha or intraarticular injection of Freund's complete adjuvant (

103 second group (group B, 64 patients) received intraarticular injection of gadopentetate dimeglumine an

104 first group (group A, 63 patients) received intraarticular injection of gadopentetate dimeglumine, r

105 A single intraarticular injection of gp130-RAPS suppressed chroni

106 Intraarticular injection of IL-1 or LPS was associated w

107 In vivo, intraarticular injection of lentiviral Wnt7a strongly at

108 te adjuvant and then challenged on day 21 by intraarticular injection of mBSA into the right knee.

109 NKi was injected daily starting 4 days after intraarticular injection of mBSA into wild-type (WT) mic

110 Intraarticular injection of mBSA uniformly induced sever

111 min (mBSA), and arthritis was induced by the intraarticular injection of mBSA.

112 Intraarticular injection of mesenchymal stromal cells (M

113 Intraarticular injection of modified cells significantly

114 model of knee joint OA pain was generated by intraarticular injection of mono-iodoacetate (MIA) in Sp

115 animal model of facet joint degeneration by intraarticular injection of monosodium iodoacetate (MIA)

116 2 and their wild-type controls were given an intraarticular injection of muramyl dipeptide (MDP), pep

117 in an immunodeficiency rat model of OA after intraarticular injection of murine MDSCs expressing bone

118 We demonstrate that a single intraarticular injection of Nano-PAZII can effectively r

119 Rabbits were given an intraarticular injection of rHuIL-1 alpha.

120 Following intraarticular injection of S. aureus, PBD155-treated mi

121 l of antigen-induced inflammatory arthritis, intraarticular injection of Sdc3(-/-) MSCs yielded enhan

122 Experimental OA was induced in rats by intraarticular injection of sodium mono-iodoacetate (MIA

123 justment rate (P=.08), target error (P=.07), intraarticular injection rate (P>.99), and arthrography

124 Intraarticular injection rate was 100% (45 of 45).

125 ere intravenously administered 4 hours after intraarticular injection to quantify PMN recruitment and

126 viocytes and expressed transiently following intraarticular injection.

127 was delivered to the injured knee by direct intraarticular injection.

128 The remaining rats were given intraarticular injections (50 microl/injection) of eithe

129 Intraarticular injections (50 mul/injection) of phosphat

130 present study, we evaluated the efficacy of intraarticular injections of AM hydrogels with and witho

131 changes were determined in mice treated with intraarticular injections of CFA.

132 Both physical therapy and intraarticular injections of glucocorticoids have been s

133 In this canine model of OA, the series of intraarticular injections of HA did not alter developmen

134 ections only (control), and 24 rats received intraarticular injections of lipopolysaccharide-doped po

135 d material which was markedly improved after intraarticular injections of liposomal A2AR agonist.

136 duration < or =12 months) were treated with intraarticular injections of methylprednisolone into all

137 mplications, whereas the impact and risks of intraarticular injections remain unclear.

138 Our findings indicate that intraarticular lubricin injection following an ACL injur

139 e randomized to early intervention (EI) with intraarticular methylprednisolone into all synovitic joi

140 us calcergy model and a model of OA in which intraarticular mineralization is a prominent feature.

141 rs and tolerance to the analgesic effects of intraarticular morphine.

142 quential T1-calculated images obtained after intraarticular (n = 2) or intravenous (n = 2) injection.

143 ar gadolinium) or T2-weighted gradient-echo (intraarticular normal saline) images were obtained in th

144 nd PGE2 production, and 2) neutralization of intraarticular OPN with anti-OPN antiserum augmented NO

145 e data indicate that one of the functions of intraarticular OPN, which is overexpressed in OA cartila

146 hritis, and patients receiving only topical, intraarticular, or intrabursal corticosteroids.

147 the 3T MRI-unit for assessment of potential intraarticular pathologies in patients with acute and ch

148 ontrast material was injected to confirm the intraarticular position of the needle.

149 through synovium was measured at controlled intraarticular pressures using a rabbit knee model in vi

150 Three patients also underwent US with intraarticular saline infusion.

151 Conclusion Intraarticular steroid injection had a substantially low

152 key requirement for rational development of intraarticular therapeutics.

153 e exacerbated autoimmune arthritis, and that intraarticular TRAIL gene transfer ameliorated the disea

154 Intraarticular transfer of IL-1 receptor antagonist (IL-

155 ely to human rheumatoid joints and to obtain intraarticular, transgene expression.

156 tagonist (IL-1Ra) has been evaluated for the intraarticular treatment of osteoarthritis.

157 Additionally, intraarticular treatment with FGF-2 and FGF-8 was found