ライフサイエンスコーパス: intracellular distribution

1 microtubules are important in this enzyme's intracellular distribution.

2 w the molecule's cell surface expression and intracellular distribution.

3 expression, their pH sensitivity, and their intracellular distribution.

4 orylation status of GSK-3beta can affect its intracellular distribution.

5 e mechanism that mediates its activation and intracellular distribution.

6 cts of mutations in dynein regulators on its intracellular distribution.

7 dependent on intact actin polymers for their intracellular distribution.

8 pression of noncanonical Wnts modulates Rok2 intracellular distribution.

9 ylation of FAK, and a dramatic change in its intracellular distribution.

10 nctional status of eIF4E is regulated by its intracellular distribution.

11 undred RyRs, creating a spatially nonuniform intracellular distribution.

12 directly impacting both the GEF function and intracellular distribution.

13 G(q/11) signaling but are different in their intracellular distribution.

14 s the properties of these proteins and their intracellular distribution.

15 both in terms of total number of signals and intracellular distribution.

16 ng in instantaneous release of Ce6 and rapid intracellular distribution.

17 e Arp2/3 complex in cells by determining its intracellular distribution.

18 associated with enhanced efflux and altered intracellular distribution.

19 FGF-2 post-translational modification to its intracellular distribution.

20 to B-adrenergic stimulation that alter Them1 intracellular distribution.

21 for the absence of ERMES correlates with its intracellular distribution.

22 uorescent zinc(II) complexes to assess their intracellular distribution.

23 s were absent, junctophilin 2 had sarcomeric intracellular distribution.

24 activation of PKGI with cGMP regulated SSG1 intracellular distribution.

25 primarily at the levels of transcription and intracellular distribution.

26 ociation with protein partners, and thus its intracellular distribution.

27 wavelength, allowing for the observation of intracellular distribution.

28 in COS7 and NIH3T3 cells exhibited distinct intracellular distributions.

29 ne cells of the ovary, they display distinct intracellular distributions.

30 phoinositides (PPIns) from the PM alters the intracellular distribution and activity of K- and H-Ras

31 ory cells and that BDNF(Met) could alter the intracellular distribution and activity-dependent secret

32 ted to conserve ATP and to ensure its proper intracellular distribution and coordination with other m

33 This manuscript describes the distinctive intracellular distribution and enzymatic activity of the

34 ed sensors of free GTP offered insights into intracellular distribution and function of GTP molecules

35 hannel alpha-subunit Kv4.3 and regulates its intracellular distribution and gating properties.

36 It displays a broad intracellular distribution and is present in numerous co

37 FREB has an intracellular distribution and lacks a canonical transme

38 Intracellular distribution and metabolic changes were ob

39 inhibitors to quantitatively visualize their intracellular distribution and protein target-specific b

40 We aimed to investigate: (i) ApoJ-Glyc intracellular distribution and secretion during ischaemi

41 olecular masses but differed considerably in intracellular distribution and solubility.

42 To assess the intracellular distribution and stability of 125I-ODN del

43 ective ASGP-Rs showed normal ligand binding, intracellular distribution and trafficking patterns, and

44 ever the spatial and temporal changes in the intracellular distribution and translocation of VEGFRs t

45 to establish their characteristic asymmetric intracellular distributions and coordinate planar polari

46 te 95% amino acid sequence identity, similar intracellular distribution, and broad tissue distributio

47 teady-state levels, kinetics of degradation, intracellular distribution, and internalization rates.

48 e Cat-domain is soluble, exhibits a disperse intracellular distribution, and is subject to ubiquityla

49 nhanced tumor cell internalization, improved intracellular distribution, and potentiated anticancer a

50 CH 1 (March-I) regulates surface expression, intracellular distribution, and survival of pMHC-II in D

51 evels of specific cyclins and CDKs and their intracellular distribution, and the relative levels of m

52 with the DAB2IP-239N transcript exhibited an intracellular distribution, and VEGFR2 remained associat

53 of wild yeast differ biochemically, in their intracellular distributions, and in their ability to pro

54 displays an intriguing cell cycle-dependent intracellular distribution, apparently moving from the c

55 r compartments and that sterol transport and intracellular distribution are regulated by PIPs.

56 owever, the dynamics of MMP-9 production and intracellular distribution as well as the mechanisms res

57 actin polymerization, network formation, and intracellular distribution, as well as inhibits beta(2)

58 o total eNOS but did not change the relative intracellular distribution between these domains.

59 es resulted in similar expression levels and intracellular distribution, but AC6mut expression was as

60 ght form of a reporter K15P molecule and its intracellular distribution change when KSHV switches fro

61 ut the intensity of the signal increased and intracellular distribution changed dramatically in both

62 We investigated whether 27HC can change the intracellular distribution cholesterol and reduce hepati

63 We analyzed their intracellular distribution, co-localization and oligomer

64 The GTCTR chimera had a more predominant intracellular distribution compared to the TR.

65 sma membrane, whereas BCCa-I has a punctate, intracellular distribution consistent with a vesicular l

66 nding, increased cell death, and an abnormal intracellular distribution, consistent with protein dysf

67 ent study, we analyzed bFGF internalization, intracellular distribution, degradation, and stimulation

68 Reported structural, phenotypic, and intracellular distribution differences between the two C

69 ated ROS, reduced mitochondrial respiration, intracellular distribution differences, and altered move

70 igh levels in human cardiac myocytes with an intracellular distribution distinct from that of PDE3A a

71 In contrast, as expected from its intracellular distribution, endogenous or overexpressed

72 e constitutively active Rab5Q79L enhances m4 intracellular distribution, even in unstimulated cells.

73 GFP to Pex7p's COOH terminus shifts Pex7p's intracellular distribution from predominantly cytosolic

74 ration dependent manner marked by a shift in intracellular distribution from punctate spots to diffus

75 P1 (K38A and D231N) dramatically changed its intracellular distribution from punctate vesicular struc

76 Aergic neurons impacted baseline DAT surface:intracellular distribution in DAergic terminals from fem

77 se in myosin phosphorylation and a change in intracellular distribution in fibroblasts on fibrotic lu

78 We show here that GLUT8 has a novel intracellular distribution in hippocampal neurons and is

79 t the factors that regulate their uptake and intracellular distribution in living cells.

80 f the axonal transport machinery driving APP intracellular distribution in neurons, and stress DYRK1A

81 the function of syntaxin 13 we examined its intracellular distribution in nonpolarized cells.

82 cell-cell interactions, but their prominent intracellular distribution in vivo and different knock-o

83 ed on four viral proteins that have distinct intracellular distributions in infected cells, hemagglut

84 ng to cell type and have different roles and intracellular distributions in vivo.

85 f the time-dependence of cellular uptake and intracellular distribution, in evaluating and advancing

86 s localized to two cell types with differing intracellular distributions, insofar as staining was see

87 hibit cytotoxicity, and are characterized by intracellular distributions invariably dictated by their

88 revisiae, high affinity manganese uptake and intracellular distribution involve two members of the Nr

89 We also show that PML intracellular distribution is altered in NPM1-mutated AM

90 ence techniques indicate that this change in intracellular distribution is characterized by a shift o

91 results demonstrate that the dynamic Vangl2 intracellular distribution is coordinated with and neces

92 e, is quite similar in all fibers, but their intracellular distribution is fiber type-dependent.

93 P101 tagged with GFP, we discovered that its intracellular distribution is highly dynamic and include

94 e well known; however, the regulation of Suc intracellular distribution is poorly understood.

95 associate with the plasma membrane, and its intracellular distribution is unaffected by mutations in

96 r understanding of cellular internalization, intracellular distribution mechanisms and interactions o

97 oes not alter beta-catenin protein levels or intracellular distribution nor does it induce an inhibit

98 As a demonstration, we show that the intracellular distribution of a fluorescein-labeled TFO

99 In this study we show for the first time the intracellular distribution of a K39 kinesin homologue in

100 Pb altered the levels, characteristics, and intracellular distribution of Abeta staining and amyloid

101 These findings suggest that intracellular distribution of activated TNF receptors ma

102 by confocal microscopy indicated a distinct intracellular distribution of Alexa-568-labeled GV-LDL a

103 host-pathogen interactions has revealed the intracellular distribution of antibiotics at a new level

104 In addition, the intracellular distribution of antioxidative enzymes may

105 he cis -acting sequence requirements and the intracellular distribution of APOBEC-1 in yeast were sim

106 Here, we have further investigated the intracellular distribution of AtELP.

107 Intracellular distribution of ATP in normal physiologica

108 nant clone expressing ipaH(7.8) restored the intracellular distribution of bacteria to that seen with

109 Both compounds altered the intracellular distribution of beta-catenin and GSK3beta

110 ding on regulation of PI3Kgamma activity and intracellular distribution of betaARs.

111 or dominant negative Rab mutants changed the intracellular distribution of capsids and affected the i

112 The intracellular distribution of CAS resembles that of tubu

113 The intracellular distribution of CbpA alters dramatically w

114 First, the intracellular distribution of CCS determines SOD1 partit

115 onfocal microscopy analyses revealed altered intracellular distribution of CD1d and LAMP-1 in LT-trea

116 differ with regard to how they influence the intracellular distribution of CD1d, its rate of internal

117 Here we show that Rad24 controls the intracellular distribution of Cdc25.

118 que with multivariate modeling to reveal the intracellular distribution of cell components.

119 tigate the mechanisms of cellular uptake and intracellular distribution of cell-penetrating peptides.

120 vity is highly specific to Rev function: the intracellular distribution of cellular poly(A)(+) mRNA,

121 The intracellular distribution of CF3CO-adducts was studied

122 BP), plays a crucial role in controlling the intracellular distribution of cholesterol.

123 cells and in the mouse lung and altered the intracellular distribution of clathrin heavy chains.

124 The key role in the intracellular distribution of copper belongs to the rece

125 In the present study, the intracellular distribution of CPD was examined in AtT-20

126 pr and Vpx functions and also shows that the intracellular distribution of CUL4A and CUL4B can vary b

127 Protein levels and intracellular distribution of Cx43 and other key markers

128 dings suggest that Roughex can influence the intracellular distribution of cyclin A and define Roughe

129 exit from mitosis, possibly by altering the intracellular distribution of cyclin B1.

130 orylation plays a key role in regulating the intracellular distribution of cyclins.

131 an examination of the quantity, quality and intracellular distribution of deltaAg and deltaRNA in se

132 rk that opens up new venues for the study of intracellular distribution of dinuclear transition metal

133 ous fractionation technique to determine the intracellular distribution of DMAPP in isoprene-emitting

134 Intracellular distribution of drug compounds is dependen

135 The precise intracellular distribution of each of these proteins dep

136 proteins in COS-7 and CHO cells to study the intracellular distribution of ELOVL4 and to identify pos

137 A comparison was made with the intracellular distribution of endogenous cytochrome c ba

138 mic reticulum, had no apparent effect on the intracellular distribution of F13L-GFP, suggesting that

139 rtment, and observed a diurnal change in the intracellular distribution of Fabp7 mRNA in molecular la

140 Images of the intracellular distribution of FFP18 show that >65% is lo

141 We have characterized the intracellular distribution of fluorescently tagged phosp

142 ient to ensure efficient cellular uptake and intracellular distribution of fully unprotected peptides

143 The expression and intracellular distribution of G1-phase regulatory protei

144 onfocal analysis revealed markedly different intracellular distribution of GAPDH between nucleus and

145 The novel intracellular distribution of Gbeta(5).RGS protein compl

146 the expression, proteolytic processing, and intracellular distribution of genetic PLD3 variants prev

147 on of the Rho GAP domain of ExoS changed the intracellular distribution of GFP-Rac and GFP-Cdc42 from

148 Thus, the intracellular distribution of GSK-3 beta is dynamically

149 LANA was found to alter the intracellular distribution of GSK-3beta so that nuclear

150 s P-bodies (PBs) indicating that the dynamic intracellular distribution of hAgo2 in SGs, in PBs or at

151 We examined the intracellular distribution of Hendra virus F following e

152 smic Mallory-Denk bodies, and changes of the intracellular distribution of high-mobility group box 1

153 Analysis of the intracellular distribution of incorporated iron revealed

154 Whereas EGF promoted a more uniform intracellular distribution of initially centrally locali

155 We have previously described the detailed intracellular distribution of inositol-1,4,5-trisphospha

156 ts of five NFL mutations on the assembly and intracellular distribution of intermediate filaments (IF

157 ed to enhance receptor binding and alter the intracellular distribution of internalized FGF-2.

158 ge iron metabolism, the uptake, release, and intracellular distribution of iron in the murine macroph

159 found that beta-arr2-/- neurons show altered intracellular distribution of JNK and cJun, and that mor

160 ant colocalization were also observed in the intracellular distribution of KIF5B and beta'-COP, a com

161 anding the mechanism underlying the distinct intracellular distribution of KSHV ORF45, we identified

162 Our results suggest that the intracellular distribution of La may be linked to its RN

163 oscopy method with the capacity to infer the intracellular distribution of labeled biomolecules with

164 Examination of the intracellular distribution of late viral mRNAs revealed,

165 Levels and intracellular distribution of Lyn, CD45, COOH-terminal S

166 cardiac fibroblasts, dramatically alters the intracellular distribution of M6P/IGF2R as well as that

167 d GFP as a molecular reporter to monitor the intracellular distribution of MBP-GFP fusion proteins in

168 tions at each of these positions altered the intracellular distribution of mCD1d and reduced its abil

169 Many complexes required for the intracellular distribution of membrane proteins have bee

170 vided the means for mapping the cellular and intracellular distribution of metallothionein, thus yiel

171 Thus, vasculature of the tissue and the intracellular distribution of mitochondria can play key

172 The proper intracellular distribution of mitochondria is assumed to

173 nin 2A may play a role in maintenance of the intracellular distribution of mitochondria.

174 transporters, NRAMP2, which functions in the intracellular distribution of Mn.

175 MTs) have a multitude of functions including intracellular distribution of molecules and organelles,

176 The VSV-M protein altered the intracellular distribution of murine CD1d molecules, res

177 or proper endosomal sorting, we analyzed the intracellular distribution of mutant forms of the recept

178 mature oligodendrocytes, including aberrant intracellular distribution of myelin basic protein.

179 We propose that the intracellular distribution of Nim1 and Wee1 may serve to

180 tems-level understanding of assimilation and intracellular distribution of nitrogen.

181 ing precise information regarding uptake and intracellular distribution of NPs at the single cell lev

182 These p7 mutations altered the intracellular distribution of NS2 and E2 and appeared to

183 this study was to establish the cellular and intracellular distribution of osteopontin in the rat kid

184 to the YGG(C/A)RRC sequence also altered the intracellular distribution of other endogenous tRNAs, su

185 The primarily intracellular distribution of PAI-2 also may indicate a

186 Here, we investigated the intracellular distribution of peptidomimetic PSMA inhibi

187 e ATP-binding pocket of PI(4)K, altering the intracellular distribution of phosphatidylinositol-4-pho

188 Thus, this study demonstrates that the intracellular distribution of PKD isoenzymes are distinc

189 chanisms associated with GPCR signaling, the intracellular distribution of PKD was analyzed in live c

190 ists (GPCR) on the regulatory properties and intracellular distribution of PKD3.

191 by the distinctive substrate specificity and intracellular distribution of PKDs.

192 o hours and, additionally, information about intracellular distribution of polyphosphate and heteroge

193 Cell behavior emerges from the intracellular distribution of properties such as protrus

194 al but misplaced cell poles, we assessed the intracellular distribution of proteins that localize spe

195 Cellular uptake and intracellular distribution of PS ASOs are mediated by pr

196 revisiae is located in the mitochondria, the intracellular distribution of Q indicates the existence

197 Intracellular distribution of radioactivity revealed a t

198 er than 1 year of age, though changes in the intracellular distribution of red/green cone opsin were

199 The study of intracellular distribution of RGS3 indicated its unique

200 The intracellular distribution of Rh-CT(5-HT1A) resembles th

201 ization of replication complexes, reveal the intracellular distribution of RNA replication products,

202 The intracellular distribution of RNAs depends on interactio

203 triction at the point of division limits the intracellular distribution of RomR.

204 nal optical microscopy studies observing the intracellular distribution of rotavirus proteins and the

205 irst verified the simultaneous detection and intracellular distribution of SARS-CoV-2 M(pro) and PL(p

206 , we used confocal microscopy to examine the intracellular distribution of several RGS proteins in CO

207 oducing TGFbeta1 and the phosphorylation and intracellular distribution of SMAD2/3.

208 BoNT E expression altered the intracellular distribution of SNAP25, shifting it from a

209 k) is a ubiquitous enzyme functioning in the intracellular distribution of terminal phosphate bond en

210 Since this paradox may relate to an altered intracellular distribution of TFAM in sepsis, we tested

211 esent a general response to cell stress, the intracellular distribution of the associated responses n

212 rin internalization and an alteration in the intracellular distribution of the cation-independent man

213 In this study, we examined the intracellular distribution of the chemoreceptors by immu

214 In this study, we examine the intracellular distribution of the cornified envelope pre

215 horbol esters, suggesting that change in the intracellular distribution of the enzyme is a mechanism

216 in normal skeletal muscle that regulates the intracellular distribution of the fatty acid transport p

217 Disease-associated mutations disrupt intracellular distribution of the FP/TMEM127 protein.

218 re characterized by discrete patterns of the intracellular distribution of the immunoreaction product

219 The intracellular distribution of the insulin-responsive ami

220 concentrations in membranes, to examine the intracellular distribution of the lipid within living ce

221 The intercellular and intracellular distribution of the movement protein (MP)

222 The role of MTs in the intracellular distribution of the MP also was analyzed b

223 The intracellular distribution of the NR2 subunits was strik

224 ssion of 5-HT(2A)R with mGluR2 increased the intracellular distribution of the otherwise plasma membr

225 l of this study was to determine whether the intracellular distribution of the proapoptotic enzyme gl

226 Cleavage of MEKK1 at D68 changes the intracellular distribution of the protein from a Triton-

227 id also altered the detergent solubility and intracellular distribution of the protein when it was ex

228 P1 or PABP1-GFP resulted in heterogeneity of intracellular distribution of the protein.

229 The cellular uptake and intracellular distribution of the radioligands were char

230 play the predominant role in determining the intracellular distribution of the receptor.

231 evidence that the phosphorylation status and intracellular distribution of the RNA CUG-binding protei

232 Intracellular distribution of the SiNPs was evaluated wi

233 enin expression did not perturb the level or intracellular distribution of the tumor suppressor adeno

234 Thus, the intracellular distribution of the various ADAR1 isoforms

235 rity of both domains not only determines the intracellular distribution of the VEEV capsid but is als

236 Based on the intracellular distribution of the well established Abeta

237 In this study we investigated the intracellular distribution of the wild type (WT) and mut

238 ggesting that methylation is relevant to the intracellular distribution of these forms of FGF-2.

239 e expressed in skeletal muscle; however, the intracellular distribution of these hexokinase isoforms

240 Determination of the intracellular distribution of three previously uncharact

241 The involvement of MTs in the intracellular distribution of tobacco mosaic virus MP is

242 linked carbohydrates, and measurement of the intracellular distribution of TPO has often relied on th

243 h as angiotensin II and appears to alter the intracellular distribution of TRPC6 protein.

244 Expression, localization, and intracellular distribution of TRPP Ca(2+) channels were

245 oxygen species, and that cells can regulate intracellular distribution of YHb in accordance with thi

246 tive in the GEF activity of TRAPP II and the intracellular distribution of Ypt1 and Ypt31/32.

247 Neither did zinc deficiency affect the intracellular distribution of ZIP7 in mammalian cells.

248 , or after dissection from the lens, and the intracellular distributions of crystallins were examined

249 Intracellular distributions of filamentous actin (F-acti

250 This treatment permits observing intracellular distributions of macromolecular pools, iso

251 oexpress VGF and SAAS peptides, and that the intracellular distributions of these peptides in arcuate

252 We also demonstrate that the intracellular distributions of ZnT6 as well as ZnT4 are

253 lective, because insulin does not affect the intracellular distribution or cell-surface localization

254 the actin filaments without inhibiting their intracellular distribution or the activity of the myosin

255 te with the human CD1b isoform, which has an intracellular distribution pattern similar to that of mu

256 ent in hippocampal projection neurons, their intracellular distribution patterns differ.

257 rmal folding and overall Slo1 and caveolin-1 intracellular distribution patterns.

258 s is necessary to achieve appropriate IGF-IR intracellular distribution point to the important role t

259 restingly, individual isoforms show distinct intracellular distributions: QKI-6 and QKI-7 are localiz

260 ic activity impacts on NAD(+) levels and its intracellular distribution remains unclear.

261 Identifying S100 intracellular distribution, site of action, and protein

262 fferent GPI-anchored proteins have different intracellular distributions; some (such as the folate re

263 in enterocytes maintains a homeostatic TLR9 intracellular distribution, supporting mucosal tolerance

264 Intracellular distribution varied among these non-toxic

265 Based on their copurification and intracellular distribution, vaults may be involved in th

266 reduced basicity were synthesized, and their intracellular distribution was evaluated.

267 Their intracellular distribution was similar to that of the en

268 in addition to assessing cellular uptake and intracellular distribution, we demonstrated that the Ru-

269 81W mutant had an endoplasmic reticulum-like intracellular distribution, whereas L22V and wild-type A

270 adate inhibited the cell cycle dependency of intracellular distribution, while okadaic acid had littl

271 s, and a rho 1-GFP fusion gene showed mostly intracellular distribution with a faint fluorescence tow