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1 redoxin-2 (PRDX2), a ubiquitous redox-active intracellular enzyme.
2 g the availability of specific nutrients and intracellular enzymes.
3 owed the selective and sensitive analysis of intracellular enzymes.
4 ncentrations within tissues are modulated by intracellular enzymes.
5 gonucleotides to cells, and stability toward intracellular enzymes.
6 hange the catalytic activity of a variety of intracellular enzymes.
7 enes that could be putatively assigned to 13 intracellular enzymes.
8 rgets, including receptors, ion channels and intracellular enzymes.
9 ross biological membranes to reach essential intracellular enzymes.
10 y is well-known to comprise three classes of intracellular enzymes.
12 cascade of sarcolemmal receptor activation, intracellular enzyme activation, and ultimately mitochon
14 novel approach for the study of single-cell intracellular enzyme activity at various temperatures, u
20 zation-free labeling of neuronal cell types, intracellular enzymes, and synaptic proteins in tissue s
21 athways with human disease and identified 12 intracellular enzymes as potential therapeutic targets.
22 The adenylyl cyclases (ACs) are a family of intracellular enzymes associated with signal transductio
23 de, which is a fluorogenic substrate for the intracellular enzyme beta-galactosidase, we also assayed
24 acterial cells and the extraction of a large intracellular enzyme, beta-galactosidase, is demonstrate
25 idoreductase 1 (NQO1) appears to be the main intracellular enzyme catalyzing idebenone reduction.
27 Free ADMA is actively metabolized by the intracellular enzyme dimethylarginine dimethylaminohydro
28 he plasma membrane transporter GlyT2 and the intracellular enzyme glutamate decarboxylase supply the
29 odextrins (Mal-I and Mal-II), and a range of intracellular enzymes have been purified that reportedly
30 gregation of GLUT-1 (luminal>abluminal), the intracellular enzyme hexokinase was also asymmetrically
31 by inhibiting phosphodiesterase 7 (PDE7), an intracellular enzyme highly expressed in the corticomeso
32 ar myocyte, implying a specific role for the intracellular enzyme in HCO3- transport, and hence pHi r
33 se associated genetic variations often cause intracellular enzyme inactivation, dysregulation and ins
34 egy should be applicable to a broad range of intracellular enzymes, including phosphatases, proteases
35 oxygenase (IDO), an interferon gamma-induced intracellular enzyme, inhibits lymphocyte proliferation
36 Glutathione peroxidase (GSHPx) is a critical intracellular enzyme involved in detoxification of hydro
37 ptors on cells, triggering the activation of intracellular enzymes known as Janus kinases (JAKs).
39 e basis for this difference, we compared the intracellular enzyme levels following phage infection as
41 urn, allows both components to interact with intracellular enzymes or ion channels and modulate their
43 n within the mediobasal hypothalamus via the intracellular enzyme, phosphoinositol-3-kinase (PI3K).
44 phate (PI4P), synthesized principally by two intracellular enzymes, PI4-kinases IIIalpha and IIIb; th
46 ulation of L-lactate dehydrogenase (LDH), an intracellular enzyme present in most of all body tissues
47 only through probe activation by a specific intracellular enzyme present in tumor cells of multiple
49 ned for the steady-state reaction rate of an intracellular enzyme, recruited to the plasma membrane b
50 etoprofen showed that CYP450 is not the sole intracellular enzyme responsible for intracellular trans
51 inhibition of phosphodiesterase 7 (PDE7), an intracellular enzyme responsible for the degradation of
52 Ubiquitin ligases (Ub-ligases) are essential intracellular enzymes responsible for the regulation of
54 ected genes is shown to be suppressed by two intracellular enzymes, RNase L and protein kinase PKR, w
55 y the use of inhibitors directed against key intracellular enzymes, some of which have been used in c
56 nal domain interacts with LARGE, defining an intracellular enzyme-substrate recognition motif necessa
57 weight antioxidants such as glutathione and intracellular enzymes such as superoxide dismutase (SOD)
61 for type 2 iodothyronine deiodinase (D2), an intracellular enzyme that activates thyroid hormone (T3)
62 ulum aminopeptidase 1 (ERAP1), a polymorphic intracellular enzyme that can regulate cytotoxic T-lymph
63 at human PDCs express high levels of IDO, an intracellular enzyme that catabolizes tryptophan degrada
64 ompetitive inhibitor of 5alpha-reductase, an intracellular enzyme that converts testosterone to dihyd
65 ity of indoleamine 2,3-dioxygenase (IDO), an intracellular enzyme that converts tryptophan into metab
67 The proteasome is a ubiquitous and essential intracellular enzyme that degrades many proteins regulat
69 rosine phosphatase 1B (PTP1B) is an abundant intracellular enzyme that is thought to act as a negativ
70 yl-peptide cyclotransferase-like (QPCTL), an intracellular enzyme that mediates N-terminal modificati
71 ingosine 1-phosphate (S1P) lyase (SPL) is an intracellular enzyme that mediates the irreversible degr
72 mic reticulum aminopeptidase 1 (ERAP1) is an intracellular enzyme that optimizes the peptide cargo of
73 e A:cholesterol acyltransferase (ACAT) is an intracellular enzyme that produces cholesteryl esters in
75 , by histone deacetylases (Hdacs), which are intracellular enzymes that directly affect chromatin str
76 ent phosphorylation and dephosphorylation of intracellular enzymes that is therapeutically accessible
77 glucose for plasma membrane transporters and intracellular enzymes; the lumped constant (LC) can be u
80 how that Hcy-thiolactone is hydrolyzed by an intracellular enzyme, which we have purified to homogene
81 ogenic substrates to monitor the activity of intracellular enzymes, while adjusting the local tempera
82 protein tyrosine phosphatase (PTP)-MEG2, an intracellular enzyme with a putative lipid-binding domai
83 c superoxide dismutase (SOD1) is an abundant intracellular enzyme with an essential role in antioxida
84 be directly applied to quantify a variety of intracellular enzymes with available fluorogenic substra