ライフサイエンスコーパス: intracellular pathogen

1 or obligate saprophytism in this facultative intracellular pathogen.

2 a monocytogenes, a Gram-positive facultative intracellular pathogen.

3 entral metabolic properties of this obligate intracellular pathogen.

4 molecule that activates the virulence of an intracellular pathogen.

5 are engaged to report on the presence of an intracellular pathogen.

6 nding the immunopathogenesis related to this intracellular pathogen.

7 it protective intestinal immunity against an intracellular pathogen.

8 with Mycobacterium tuberculosis, a notorious intracellular pathogen.

9 h from a soil dwelling bacterium to a deadly intracellular pathogen.

10 tified several host genes important for this intracellular pathogen.

11 nomous immunity that restrict replication of intracellular pathogens.

12 enotype that participates in defense against intracellular pathogens.

13 ne responses and protective efficacy against intracellular pathogens.

14 lic macromolecules or organelles, as well as intracellular pathogens.

15 ) and facilitated vancomycin delivery to the intracellular pathogens.

16 form of autophagy that mediates clearance of intracellular pathogens.

17 the role of IFN-gamma in protection against intracellular pathogens.

18 spensable step for a successful infection by intracellular pathogens.

19 re major cells that provide immunity against intracellular pathogens.

20 bolic program that is also used for clearing intracellular pathogens.

21 comycin against intracellular MRSA and other intracellular pathogens.

22 otential for early-life immunization against intracellular pathogens.

23 aling the danger of cellular exploitation by intracellular pathogens.

24 in wild-type macrophages and serves to kill intracellular pathogens.

25 sense metabolic dysfunction or infection by intracellular pathogens.

26 oles in innate and adaptive immunity against intracellular pathogens.

27 y, enabling the detection and elimination of intracellular pathogens.

28 and used these to study T cell responses to intracellular pathogens.

29 ing PNAs conjugated to CPPs to better target intracellular pathogens.

30 for its role in regulating autophagy against intracellular pathogens.

31 and immunotherapies to protect infants from intracellular pathogens.

32 nts are highly susceptible to infection with intracellular pathogens.

33 ses the capacity of macrophages to eliminate intracellular pathogens.

34 c strategies to address infections caused by intracellular pathogens.

35 tegies that protect individual cells against intracellular pathogens.

36 lays a critical role in host defense against intracellular pathogens.

37 a key cytokine that mediates host defense to intracellular pathogens.

38 mbranes, focal adhesions, and the surface of intracellular pathogens.

39 Brucellae are facultative intracellular pathogens.

40 it has been well-established for many other intracellular pathogens.

41 is lessons that may be informative for other intracellular pathogens.

42 critical for host defense upon reexposure to intracellular pathogens.

43 ceptor serves to detect complement-opsonized intracellular pathogens.

44 logical aspects of these peculiar eukaryotic intracellular pathogens.

45 quired for the control of a diverse array of intracellular pathogens.

46 ion of both cellular components and invading intracellular pathogens.

47 richia coli, has not been annotated for most intracellular pathogens.

48 ial for cell autonomous immunity to numerous intracellular pathogens.

49 or limiting growth of both extracellular and intracellular pathogens.

50 ulate expression of genes induced by natural intracellular pathogens.

51 es and as reservoirs for proteins that fight intracellular pathogens.

52 t defense molecules that function to control intracellular pathogens.

53 tegral part of host defense against invading intracellular pathogens.

54 ellular components and defends cells against intracellular pathogens.

55 ety of microbes, including extracellular and intracellular pathogens.

56 at provides a host defense mechanism against intracellular pathogens.

57 oinflammatory TH1 responses needed to combat intracellular pathogens.

58 responses for effective vaccination against intracellular pathogens.

59 rse arsenal of effector mechanisms to target intracellular pathogens.

60 ously Nramp1) mediates resistance to several intracellular pathogens.

61 karyotic cells and a source of nutrients for intracellular pathogens.

62 orphisms with an increased susceptibility to intracellular pathogens.

63 mediately available to fight the invasion of intracellular pathogens.

64 hils is a crucial process for the control of intracellular pathogens.

65 Neonates often develop poor immunity against intracellular pathogens.

66 lls, which serve as the replicative niche of intracellular pathogens.

67 l (T(CD8+)) immunosurveillance of tumors and intracellular pathogens.

68 However, for the control of intracellular pathogens, a strong Th1 response character

69 Intracellular pathogens actively avoid delivery to or di

70 Not only have intracellular pathogens adapted their metabolism to the

71 d a major driving force for the evolution of intracellular pathogens, allowing them to survive and re

72 s often generate incomplete immunity against intracellular pathogens, although the mechanism of this

73 at limits collateral tissue damage due to an intracellular pathogen and promotes host survival.

74 Cryptococcus neoformans is a facultative intracellular pathogen and the causative agent of crypto

75 a tularensis is a Gram-negative, facultative intracellular pathogen and the causative agent of tulare

76 s provide durable protection against diverse intracellular pathogens and can be broadly segregated in

77 nes and immunotherapeutic strategies against intracellular pathogens and cancer.

78 Intracellular pathogens and danger signals trigger the f

79 uced upon viral infection and infection with intracellular pathogens and genes coexpressed with retro

80 by no means limited to direct elimination of intracellular pathogens and includes a stratified array

81 tune macrophage effector functions to combat intracellular pathogens and reduce inflammatory tissue d

82 D8 T cells are a potent tool for eliminating intracellular pathogens and tumor cells.

83 ion and CD8 T cell-mediated immunity against intracellular pathogens and tumors.

84 patterns that are associated with damage or intracellular pathogens, and assemble into cytosolic com

85 microbicidal effector molecules that destroy intracellular pathogens, and at low concentrations they

86 uring nutrient insufficiency, eradication of intracellular pathogens, and counteracting aging through

87 Intracellular pathogens are differentially sensed by the

88 Intracellular pathogens are responsible for an enormous

89 Intracellular pathogens are responsible for much of the

90 hat organize and use immune proteins to kill intracellular pathogens as well as central players in th

91 considered to be one of the most successful intracellular pathogens, because it can reproduce in var

92 The Gram-negative intracellular pathogen Burkholderia pseudomallei is the

93 provide protection from the environment for intracellular pathogens, but acquisition of nutrients an

94 + T cells play a central role in eradicating intracellular pathogens, but also are important for noni

95 ellular immunity is critical for controlling intracellular pathogens, but individual cellular dynamic

96 Memory CD8 T cells protect against intracellular pathogens by scanning host cell surfaces;

97 Intracellular pathogens can thrive within mammalian cell

98 ularensis is a highly virulent Gram-negative intracellular pathogen capable of infecting a vast diver

99 sting with previously reported mechanisms of intracellular pathogen carriage by phagocytes, we show S

100 Many intracellular pathogens cause disease by subverting macr

101 pathogens that can also act as a facultative intracellular pathogen causing infections that are extre

102 The obligate-intracellular pathogen Chlamydia trachomatis (Ct) has un

103 The obligate intracellular pathogen Chlamydia trachomatis is the lead

104 tracellular bacteria, including the obligate intracellular pathogen Chlamydia trachomatis, grow withi

105 The first, found in the intracellular pathogen Chlamydia trachomatis, uses YhhQ

106 In this review, we describe mechanisms of intracellular pathogen clearance that rely on the autoph

107 lize antimicrobial peptides to improve their intracellular pathogen clearance.

108 Intracellular pathogens commonly manipulate the host lys

109 However, like any scientific concept, the intracellular pathogen concept can become a dogma that c

110 The intracellular pathogen concept classifies pathogenic mic

111 Although the intracellular pathogen concept remains useful, it should

112 The obligate intracellular pathogen Coxiella burnetii displays antiap

113 he intracellular replication of the obligate intracellular pathogen Coxiella burnetii, as it allows t

114 Upon infection with an intracellular pathogen, cytotoxic CD8(+) T cells develop

115 Obligate intracellular pathogens depend on their host for growth

116 Intracellular pathogens directly alter host cells in ord

117 Several intracellular pathogens display the ability to propagate

118 cids (PNAs) present a novel method to target intracellular pathogens due to their unique mechanism of

119 pattern molecules and by various strategies intracellular pathogens employ to alter cellular microen

120 These results reveal how the exotoxin of an intracellular pathogen engages host pathways for packagi

121 GBPs are essential for immunity against intracellular pathogens, especially for Toxoplasma gondi

122 Mycobacterium tuberculosis is an adaptable intracellular pathogen, existing in both dormant as well

123 Many intracellular pathogens exploit host secretory trafficki

124 sitions from an environmental organism to an intracellular pathogen following its ingestion by suscep

125 Xenophagy targets intracellular pathogens for destruction by the host auto

126 that utilizes ER-derived membranes to target intracellular pathogens for destruction.

127 The facultative intracellular pathogen Francisella tularensis can persis

128 We used a model intracellular pathogen, Francisella novicida, to begin c

129 As an intracellular pathogen, Francisella survives and replica

130 activity, demonstrating conservation between intracellular pathogens from different phylogenetic king

131 Listeria monocytogenes is a Gram-positive, intracellular pathogen harboring the surface-associated

132 Thus, this intracellular pathogen has evolved multiple mechanisms t

133 Epigenetic manipulation of host cells by intracellular pathogens has become increasingly evident.

134 These intracellular pathogens have evolved a sophisticated inv

135 Intracellular pathogens have evolved intricate mechanism

136 Many intracellular pathogens have, however, developed mechani

137 ion recently emerged as a mechanism by which intracellular pathogens hijack cellular resources and es

138 phages play an essential role in controlling intracellular pathogens; however, macrophages also serve

139 synergisms may enable 'special' tolerance of intracellular pathogens in bat hosts; paradoxically, thi

140 on domain was not necessary for reducing the intracellular pathogens in cultured osteoblasts or in tw

141 and increased susceptibility to a number of intracellular pathogens in individuals infected with hum

142 m (NOX2) are critical for the elimination of intracellular pathogens in many infections.

143 phering the redox environment encountered by intracellular pathogens in the mammalian cytosol is chal

144 eded to treat chronic bacterial diseases and intracellular pathogens, in particular, are very difficu

145 oves Mn and other essential metals to starve intracellular pathogens; in the extracellular space, cal

146 branes to overcome barriers for treatment of intracellular pathogens including Brucella melitensis.

147 Autophagy is a cellular response to intracellular pathogens including mycobacteria and is in

148 Several intracellular pathogens, including a key etiological age

149 ily conserved process that restricts certain intracellular pathogens, including HSV-1.

150 Many intracellular pathogens, including Salmonella typhimuriu

151 n essential mediator of host defense against intracellular pathogens, including the protozoan parasit

152 Many intracellular pathogens, including the protozoan parasit

153 +) T cells are critical for the clearance of intracellular pathogens, including viruses, certain bact

154 Salmonella is an intracellular pathogen infecting a wide range of hosts a

155 Intracellular pathogen infection leads to proteotoxic st

156 duct of hemoglobin catabolism during certain intracellular pathogen infections, is also a potent indu

157 candidiasis disease might also have viral or intracellular pathogen infections.

158 Protective immunity against intracellular pathogens involves the induction of robust

159 ytotoxic T lymphocyte (CTL) response against intracellular pathogens is generally accomplished by imm

160 One common threat for intracellular pathogens is the homeostatic process of au

161 s, which provide immune surveillance against intracellular pathogens, is higher on lymphoid cells tha

162 sponse contributes to increased clearance of intracellular pathogens, it seems that NLRC4 inflammasom

163 Macrophage intracellular pathogen killing is defective in cystic fi

164 e protein aggregates, damaged organelles, or intracellular pathogens leads to diseases, including neu

165 The intracellular pathogen Legionella pneumophila encodes Ri

166 The intracellular pathogen Legionella pneumophila interferes

167 The intracellular pathogen Legionella pneumophila resides in

168 The facultative intracellular pathogen Legionella pneumophila, the causa

169 The intracellular pathogen, Legionella pneumophila, secretes

170 Similar to other intracellular pathogens, Leishmania parasites are known

171 Many intracellular pathogens like Legionella pneumophila, Cox

172 s thought to enhance growth of the foodborne intracellular pathogen Listeria monocytogenes by promoti

173 The facultative intracellular pathogen Listeria monocytogenes causes lis

174 Genes of the facultative intracellular pathogen Listeria monocytogenes encode two

175 he other, but the Gram-positive, facultative intracellular pathogen Listeria monocytogenes is unusual

176 e-forming toxin listeriolysin O (LLO) of the intracellular pathogen Listeria monocytogenes promotes e

177 SpxA1 is an Spx-family orthologue in the intracellular pathogen Listeria monocytogenes that is es

178 ibitor that increases the sensitivity of the intracellular pathogen Listeria monocytogenes to various

179 The facultative intracellular pathogen Listeria monocytogenes uses an ac

180 During infection with the Gram-positive intracellular pathogen Listeria monocytogenes, neutrophi

181 iolysin O (LLO), secreted by the facultative intracellular pathogen Listeria monocytogenes, was postt

182 ies, including the Gram-positive facultative intracellular pathogen Listeria monocytogenes.

183 The intracellular pathogen load can tip the balance between

184 operates to remove the replication niche of intracellular pathogens, making them susceptible to phag

185 Intracellular pathogens manipulate host organelles to su

186 A subset of intracellular pathogens manipulates the UPR to promote s

187 Intracellular pathogens mobilize host signaling pathways

188 After erythrocyte invasion, the intracellular pathogen must increase host cell uptake of

189 Vaccines against mucosally invasive, intracellular pathogens must induce a myriad of immune r

190 , we studied leprosy, caused by the obligate intracellular pathogen Mycobacterium leprae, as a model.

191 n a genome-wide level, we determined for the intracellular pathogen Mycobacterium marinum whether it

192 The intracellular pathogen Mycobacterium tuberculosis (Mtb)

193 The intracellular pathogen Mycobacterium tuberculosis (Mtb)

194 For the intracellular pathogen Mycobacterium tuberculosis (Mtb),

195 Tuberculosis, caused by the intracellular pathogen Mycobacterium tuberculosis, remai

196 losis, a granulomatous disease caused by the intracellular pathogen Mycobacterium tuberculosis, we ch

197 nferior to cellular immunity directed to the intracellular pathogen Mycobacterium tuberculosis.

198 ages also serve as the cellular home for the intracellular pathogen Mycobacterium tuberculosis.

199 transcriptional response to infection by the intracellular pathogen Nematocida parisii [4].

200 nfection by the Orsay virus, another natural intracellular pathogen of C. elegans, and is distinct fr

201 tinomycete Rhodococcus equi is a facultative intracellular pathogen of macrophages and causes severe

202 Rhodococcus equi is a facultative intracellular pathogen of macrophages, relying on the pr

203 sis (HME) is caused by a tick-borne obligate intracellular pathogen of the order Rickettsiales.

204 ich displays an ankyrin-based fold common to intracellular pathogens of eukaryotes.

205 Intracellular pathogens often encode multiple SBPs, whil

206 well documented; however, the impact of this intracellular pathogen on the bAM epigenome has not been

207 esponsible for targeting cells infected with intracellular pathogens, or cells that have become malig

208 (NLRs) localize in the cytosol to recognize intracellular pathogen products and initialize the innat

209 -1alpha and not IL-1beta led to an exuberant intracellular pathogen replication and progressive non-r

210 Many intracellular pathogens reside in host-membrane-encased

211 For intracellular pathogens, residence in a vacuole provides

212 homolog DRH-1 mediates the induction of the intracellular pathogen response (IPR), a novel transcrip

213 med this common transcriptional response the intracellular pathogen response (IPR), and it includes u

214 criptional response in C. elegans called the intracellular pathogen response (IPR), which is associat

215 e nematode Caenorhabditis elegans called the intracellular pathogen response (IPR), which promotes re

216 Listeria monocytogenes is an intracellular pathogen responsible for listeriosis, a fo

217 Legionella pneumophila, an intracellular pathogen responsible for the severe pneumo

218 lis and results from an infection due to the intracellular pathogen Rickettsia 364D (also known by th

219 The intracellular pathogen Salmonella enterica has evolved a

220 However, we report here that the facultative intracellular pathogen Salmonella enterica serovar Typhi

221 gulatory system PhoP/PhoQ in the facultative intracellular pathogen Salmonella enterica serovar Typhi

222 The intracellular pathogen Salmonella enterica serovar Typhi

223 In addition, the intracellular pathogen Salmonella enterica serovar Typhi

224 also important for host-cell response to the intracellular pathogen Salmonella typhimurium, which can

225 ion of individual mouse macrophages with the intracellular pathogen Salmonella typhimurium.

226 To establish these replicative niches, intracellular pathogens secrete various virulence protei

227 ining proteins in plants and animals mediate intracellular pathogen sensing.

228 addition to its role in innate immunity, the intracellular pathogen sensor nucleotide-binding oligome

229 Many intracellular pathogens subvert host membrane traffickin

230 s substantially contribute to the control of intracellular pathogens such as human immunodeficiency v

231 flammatory responses and immune responses to intracellular pathogens such as Mycobacterium tuberculos

232 Intracellular pathogens such as Shigella flexneri and Li

233 Several intracellular pathogens, such as Brucella abortus, displ

234 The lifestyle of intracellular pathogens, such as malaria parasites, is i

235 Many intracellular pathogens, such as mammalian reovirus, mim

236 Bacterial infection caused by intracellular pathogens, such as Mycobacterium, Salmonel

237 The development of vaccines against complex intracellular pathogens, such as Plasmodium spp., where

238 lular translocation pathway for NDKs from an intracellular pathogen, suggesting that PNX1-hemichannel

239 he protozoan parasite, Toxoplasma, like many intracellular pathogens, suppresses interferon gamma (IF

240 monocytogenes, a Gram-positive, facultative intracellular pathogen, survives and replicates in the c

241 ic reticulum (rER) at the recently described intracellular 'pathogen synapse'.

242 Legionella pneumophila, an intracellular pathogen that can cause a severe pneumonia

243 ccus neoformans (Cn) is a common facultative intracellular pathogen that can cause life-threatening f

244 is a facultative intracellular pathogen that causes brucellosis, a worldw

245 in the environment as well as a facultative intracellular pathogen that causes invasive foodborne in

246 Chlamydia trachomatis is an obligate intracellular pathogen that causes sexually transmitted

247 Listeria monocytogenes is a Gram-positive intracellular pathogen that causes spontaneous abortion

248 CMV is an obligate and persistent intracellular pathogen that continually drives the produ

249 restrict the growth of L. monocytogenes, an intracellular pathogen that damages the entry vacuole.

250 Listeria monocytogenes is an intracellular pathogen that disseminates within the inte

251 Listeria monocytogenes is a facultative intracellular pathogen that escapes from phagosomes and

252 monocytogenes is a facultative intracellular pathogen that escapes from phagosomes, gro

253 Mycobacterium tuberculosis is an intracellular pathogen that infects lung macrophages and

254 nterica serovar Typhimurium is a facultative intracellular pathogen that invades the intestinal epith

255 ausative agent of brucellosis, is a stealthy intracellular pathogen that is highly pathogenic to a ra

256 Rickettsia rickettsii is an obligate intracellular pathogen that is the causative agent of Ro

257 As a strict intracellular pathogen that lives in the cytoplasm of ho

258 rium Listeria monocytogenes is a facultative intracellular pathogen that relies on the regulated secr

259 Coxiella burnetii is an intracellular pathogen that replicates in a lysosome-lik

260 Chlamydia trachomatis is an obligate intracellular pathogen that replicates in a membrane-bou

261 tiological agent of Q fever in humans, is an intracellular pathogen that replicates in an acidified p

262 Chlamydia trachomatis is an obligate intracellular pathogen that resides in a membrane-bound

263 Listeria monocytogenes is a facultative intracellular pathogen that secretes a pore-forming cyto

264 ia monocytogenes is a foodborne, facultative intracellular pathogen that secretes c-di-AMP and activa

265 Vibrio parahaemolyticus is a facultative intracellular pathogen that uses its type 3 secretion sy

266 , the causative agent of Q fever, is a human intracellular pathogen that utilizes the Icm/Dot type IV

267 We hypothesized that intracellular pathogens that can replicate within macrop

268 ative bacteria from the Legionella genus are intracellular pathogens that cause a severe form of pneu

269 Chlamydiae sp. are obligate intracellular pathogens that cause a variety of diseases

270 ce of specialized evasion strategies used by intracellular pathogens that either reside inside a vacu

271 inflammasome contributes to immunity against intracellular pathogens that express flagellin and type

272 Unlike most intracellular pathogens that gain access into host cells

273 Viruses are intracellular pathogens that hijack host cell machinery

274 Rickettsiae are obligate intracellular pathogens that induce their uptake into no

275 ay play an important role in protection from intracellular pathogens that limit class I antigen prese

276 hich could allow the immune system to detect intracellular pathogens that might otherwise escape dete

277 Brucella species are infectious intracellular pathogens that replicate in professional a

278 Salmonella enterica are invasive intracellular pathogens that replicate within a membrane

279 As an obligate intracellular pathogen, the apicomplexan parasite Toxopl

280 For intracellular pathogens, the host cell provides needed p

281 ebae could function as a training ground for intracellular pathogens, they do not fully prepare patho

282 Xenophagy, the process of eliminating intracellular pathogens through the autophagy machinery,

283 erial colonization depends on the ability of intracellular pathogens to block apoptosis and to safegu

284 a previously unidentified mechanism used by intracellular pathogens to inhibit autophagy, namely the

285 f cyclin D1 may be a common strategy used by intracellular pathogens to manipulate the host cell cycl

286 phagy recycles damaged organelles and clears intracellular pathogens to prevent their aberrant accumu

287 on (IFN-gamma), and host defense against the intracellular pathogens Toxoplasma gondii, Listeria mono

288 Anaplasma phagocytophilum is an intracellular pathogen transmitted by Ixodes scapularis

289 The mechanisms by which intracellular pathogens trigger immunosuppressive pathwa

290 Obligate intracellular pathogens undergo several cellular decisio

291 Many intracellular pathogens use rafts as an entry gate, taki

292 of mitochondria - via encounter with motile intracellular pathogens, via external pressure applied b

293 agy degrades cytoplasmic contents, including intracellular pathogens, via lysosomes and regulates int

294 ions for vaccines against cancer and several intracellular pathogens, where both humoral and cellular

295 Chlamydia bacteria are obligate intracellular pathogens which can cause a variety of dis

296 rium Listeria monocytogenes is a facultative intracellular pathogen whose virulence depends on its ab

297 Chromobacterium CipC-determines the fate of intracellular pathogens within both epithelial cells and

298 blast cells via nanotubes, thus removing the intracellular pathogen without damage to the placental c

299 c screening that blocked infectivity of this intracellular pathogen without host cell toxicity (compo

300 esponses are crucial for the control of many intracellular pathogens, yet the requirements for their