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1 o S1P receptors, and it also functions as an intracellular second messenger.
2                  Calcium (Ca) is a universal intracellular second messenger.
3 of cyclic guanosine monophosphate (cGMP), an intracellular second messenger.
4 arin and TMB-8 indicating that IP(3) was the intracellular second messenger.
5 mily of G protein-coupled receptors or as an intracellular second messenger.
6 and are essential for the regulation of this intracellular second messenger.
7 he mineral phase of bone and serves as a key intracellular second messenger.
8  to serving its better recognized role as an intracellular second messenger.
9 eful tool to elucidate the role of SPP as an intracellular second messenger.
10 P, reducing the signaling of these important intracellular second messengers.
11 lated by accessory subunits and regulated by intracellular second messengers.
12  reuptake or by blocking the inactivation of intracellular second messengers.
13 the mechanisms of ciliary beat regulation by intracellular second messengers.
14             This did not require ion flux or intracellular second messengers.
15 in cellular regulation via the generation of intracellular second messengers.
16 lations that are differentially regulated by intracellular second messengers.
17 role as biologically active molecules and as intracellular second messengers.
18  in specific tissues and variably coupled to intracellular second messengers.
19 s hydrolyze and terminate the effects of the intracellular second messenger 3',5'-cyclic adenosine mo
20 hodiesterase catalyzes the hydrolysis of the intracellular second messenger 3',5'-cyclic AMP (cAMP) i
21  the Fc mu R on NK cells and to characterize intracellular second messengers activated by IgM.
22 ich has novel dual actions acting as both an intracellular second messenger and a ligand for a family
23       As Ca(2+) is the single most important intracellular second messenger and the IP(3)-Ca(2+) sign
24    A discussion of the role of calcium as an intracellular second messenger and the pathophysiology o
25                            Hormones mobilize intracellular second messengers and initiate signalling
26 ion pathway that, upon activation, generates intracellular second messengers and leads to calcium rel
27                      A number of new 'caged' intracellular second messengers and neurotransmitters ha
28 f ion channels, as well as their coupling to intracellular second messengers and pathways, thus incre
29 ers, reorient RGC growth cones by regulating intracellular second messengers, and interact with Tollo
30     It is possible that reliance on a single intracellular second-messenger-based system, coupled wit
31 ological transitions are orchestrated by the intracellular second messenger c-di-GMP and its receptor
32 tonic and biofilm growth is dependent on the intracellular second messenger c-di-GMP.
33 ents a regulated process orchestrated by the intracellular second-messenger c-di-GMP.
34 rocesses by synthesizing and hydrolyzing the intracellular second messenger cADPr, derived from the e
35  the channels to open via an increase in the intracellular second messenger calcium.
36  that can directly mediate the action of the intracellular second messenger cAMP by activating a down
37                                          The intracellular second messenger cAMP can negatively regul
38                      Neuromodulation via the intracellular second messenger cAMP is ubiquitous at pre
39 at forskolin and IBMX can elicit through the intracellular second messenger, cAMP, a better mechanist
40                         Elevation of another intracellular second messenger, cAMP, for 5-15 min also
41     The spatial and temporal dynamics of two intracellular second messengers, cAMP and Ca2+, were sim
42 the modulation of respiratory motoneurons by intracellular second-messenger cascades.
43 uanylate cyclase (sGC) to convert GTP to the intracellular second messenger cGMP.
44 he concentrations of at least two diffusible intracellular second messengers (cGMP and Ca2+) whose ac
45 tide receptor-A (GC-A/NPRA) and produces the intracellular second messenger, cGMP, which regulates ca
46 nse of the individual cell is related to the intracellular second messenger concentration by a Michae
47  observations reveal a role for Mg(2+) as an intracellular second messenger coupling cell-surface rec
48  many normal and transformed cell types, the intracellular second messenger cyclic AMP (cAMP) blocks
49                            Signaling via the intracellular second messenger cyclic AMP (cAMP) has lon
50 tes (e.g., prostaglandin E2), as well as the intracellular second messenger cyclic AMP (cAMP).
51 nown to be promoted by the generation of the intracellular second messenger cyclic AMP (cAMP).
52    Many of these neuromodulators act via the intracellular second messenger cyclic AMP, but their eff
53 ces a UPP adhesin, which is regulated by the intracellular second messenger cyclic diguanylate monoph
54 roteins, phosphodiesterases that degrade the intracellular second messenger cyclic dimeric GMP (c-di-
55 Rs with roles in modulating Ca(2+)-dependent intracellular second messenger events implicated in dive
56 try and pyridine nucleotide metabolites, the intracellular second messengers generated upon stimulati
57  primarily by regulating the activity of key intracellular second messenger-generating systems.
58 tide phosphate (NAADP) is a Ca(2+) releasing intracellular second messenger in both mammals and echin
59 and are essential for the regulation of this intracellular second messenger in many cell types.
60 hosphate (Sph-1-P) has been implicated as an intracellular second messenger in many studies.
61  did not dismiss that S1P may function as an intracellular second messenger in other settings, they d
62 ll receptor (TCR) and function as a critical intracellular second messenger in T-cell activation.
63 ietary EPA and DHA blunted the production of intracellular second messengers, including diacylglycero
64 olipase Cgamma2 (PLCgamma2) and increases in intracellular second messengers inositol phosphates and
65 ization in dopamine neurons is caused by two intracellular second messengers: IP(3) and cyclic ADP-ri
66 tidylinositol-3-phosphate (PtdIns-3-P) as an intracellular second messenger is only just beginning to
67                     The calcium ion, a major intracellular second messenger, is a known mediator of a
68                Cyclic ADP-ribose (cADPR), an intracellular second messenger known to mobilize Ca2+ in
69                                 A variety of intracellular second messengers mediate transmitter and
70 ic di-GMP (c-di-GMP) is a broadly conserved, intracellular second-messenger molecule that regulates b
71 gnate Ag: signal transduction (generation of intracellular second messenger molecules) and Ag interna
72 y reports propose that S1P acts as either an intracellular second messenger or an extracellular ligan
73 roteins are regulated directly by binding to intracellular second messengers or signaling phospholipi
74 d Gbetagamma signaling occurs in parallel to intracellular second messenger pathways, but on differen
75 nsduction receptors are coupled to classical intracellular second messenger pathways, including cAMP-
76 ase C (PKC) activity and is regulated by the intracellular second messengers phosphatidylinositol 2-p
77 es the hyperalgesia induced by activation of intracellular second messengers, PKA and PKCepsilon, ind
78 response spatially by moving the location of intracellular second messenger production relative to ef
79                              Ca(2+), a broad intracellular second messenger, promotes both Rac1 activ
80 e as critical regulatory nodes that modulate intracellular second messenger signaling pathways, stabi
81 se (PDE) type 1, which is thought to prolong intracellular second messenger signaling within cortical
82      Nevertheless, TRs also rapidly activate intracellular second-messenger signaling pathways indepe
83 ing rely on both membrane depolarization and intracellular second-messenger signaling.
84                                Signalling by intracellular second messengers such as cyclic nucleotid
85 ic ADP ribose (cADPR) is a Ca(2+)-mobilizing intracellular second messenger synthesized from NAD by A
86 cin and motilin activate KCa channels via an intracellular second messenger system.
87 inergic, and cholinergic pathways coupled to intracellular second-messenger systems that determine th
88                               c-di-GMP is an intracellular second messenger that contains information
89   Our results indicate that 15(S)-HETE is an intracellular second messenger that facilitates transloc
90 iguanylate (c-di-GMP) is a broadly conserved intracellular second messenger that influences different
91 anosine monophosphate (cGMP) is an important intracellular second messenger that mediates multiple ti
92 e transcriptional machinery and serves as an intracellular second messenger to modify gene expression
93  is also evidence that lyso-PC may act as an intracellular second messenger transducing signals elici
94 iatal medium spiny neurons that degrades the intracellular second messengers triggered by dopamine si
95                  Because calcium is the main intracellular second messenger used by the efferent medi
96 the fact that calcium and CaM are ubiquitous intracellular second messengers used by virtually all ce
97 tor couples to heterotrimeric G proteins and intracellular second messengers, yet no studies have inv