ライフサイエンスコーパス: intramolecularly

1 transition metal catalysts, both inter- and intramolecularly.

2 the formation of two dityrosine cross-links intramolecularly.

3 aldehyde and the crotyl group is transferred intramolecularly.

4 nge in secondary structure, either inter- or intramolecularly.

5 n with naphthalene can occur both inter- and intramolecularly.

6 Itk, confirming that these domains interact intramolecularly.

7 omal site dif can occur intermolecularly and intramolecularly.

8 te where the nucleophilic heteroatom attacks intramolecularly.

9 Notch1-binding sites on Jagged1 also engage intramolecularly.

10 by associating with the dimerization region intramolecularly.

11 ion protocol can be achieved both inter- and intramolecularly.

12 BTA-based helical aggregates and UPy dimers intramolecularly.

13 le systems in which electron transfer occurs intramolecularly.

14 In this paper we describe the first intramolecularly activated precipitons.

15 he region C-terminal to the catalytic domain intramolecularly activates PRK2.

16 In solution, this occurs intramolecularly and closes the DNA-entry gate of an SMC

17 has increased rigidity via hydrogen bonding intramolecularly and improved binding affinity to the ac

18 ied peptides and IRCX-cross-linked peptides (intramolecularly and intermolecularly cross-linked), onl

19 We also demonstrated IpaB communicates intramolecularly and intermolecularly with IpaD and MxiH

20 eraction within beta subunits can occur both intramolecularly and intermolecularly.

21 ubsequently T cell autoimmunity spreads both intramolecularly and intermolecularly.

22 ndings indicate that silicon transfer occurs intramolecularly and is influenced by the nature of the

23 on in the activation loop of Aurora B occurs intramolecularly and prepares the enzyme complex for act

24 regions stimulate SIRT1 deacetylase activity intramolecularly and that the C-terminal region stably a

25 s the formation of two consecutive C-C bonds intramolecularly and undergoes aromatization under mild

26 ransfer necessary for M(+) reduction, occurs intramolecularly and via a suitably disposed pai* SOMO o

27 c coupling through the triptycene framework (intramolecularly) and by cofacial pi-stacking (intermole

28 sin heads appear to interact with each other intramolecularly, as in off-state smooth muscle myosin,

29 nal and bridging hydride ligands interchange intramolecularly at a rate of 1 s(-1) at -40 degrees C.

30 site, dif, occurs both intermolecularly and intramolecularly, at least when dif is inserted into a m

31 raries increases, the possibility of forming intramolecularly base-paired structures within templates

32 Bovine hemoglobin was covalently crosslinked intramolecularly between the 81-lysine residues on the b

33 An intramolecularly bound coumarin indicator is released in

34 The structure of the intramolecularly bound Pr segment differs from that seen

35 lower reactivity of the arm's NH(2) function intramolecularly bound to zinc, and subsequent addition

36 ches its full-length status, the tendency to intramolecularly bury non-polar surface efficiently outc

37 ree or more contiguous Gs readily associated intramolecularly but did not associate intermolecularly;

38 gy (GK) domain of PSD-95 and SAP102 interact intramolecularly, but the physiological significance of

39 the N- and C-terminal regions can be linked intramolecularly by disulfide bonds.

40 from an external reducing agent or mediated intramolecularly by internal electron transfer from anot

41 ckbone hydrogen bonds are thoroughly wrapped intramolecularly by nonpolar groups except for a few one

42 uable transformation can be readily realized intramolecularly by oxidatively generated beta-diketone-

43 The coordinated substrate is then attacked intramolecularly by the bridging hydroxide to give a nov

44 and the incipient vinyl anions were trapped intramolecularly by the internal aldehydes.

45 es the two iodine(III) centers to be bridged intramolecularly by two bidentate triflate anions.

46 t the chiral C4 of the pentose sugar and the intramolecularly C1-tethered olefin (on radical precurso

47 er molecular weight and the occurrence of an intramolecularly catalyzed prototropic exchange of the c

48 ailable, but not the cis-SNARE-complexed nor intramolecularly closed form of syntaxin 5.

49 However, linear polymers that have been intramolecularly collapsed by covalent bonds show greate

50 e immobilization of the groups that had been intramolecularly collisionally quenching the tyrosine wh

51 the sHSP IXI-domain prevents its ability to intramolecularly compete with substrate binding.

52 Intramolecularly condensed forms of HA were also observe

53 2-Iodo glycoserinyl esters were intramolecularly converted into 2-iodo serinyl glycoside

54 The reaction of the intramolecularly coordinated diaryltellurium(IV) oxide (

55 tary arm with its azaterpyridine terminal is intramolecularly coordinated to a zinc(II) porphyrin sta

56 id-labile resin, their C- and N-termini were intramolecularly coupled in solution to afford cyclic gl

57 idobutyroxy)sulfosuccin-imide ester produced intramolecularly cross-linked alpha-alpha dimers, consis

58 e compared the effects of free SNO-Hb and Hb intramolecularly cross-linked at the beta-cysteine 93 re

59 ine residues at positions 108 and 447 can be intramolecularly cross-linked by 1,2-bis(maleimido)ethan

60 Experiments with the intramolecularly cross-linked calmodulin monomer give gl

61 Intramolecularly cross-linked gamma-crystallin was first

62 spirin cross-linked hemoglobin (DCLHb) is an intramolecularly cross-linked hemoglobin-based oxygen ca

63 in cross-linked PrP 27-30 dimers, but not in intramolecularly cross-linked monomers or control sample

64 hodopsin (Rho) in its dark-adapted state was intramolecularly cross-linked with lysine-cysteine (K-C)

65 Although the intramolecularly crosslinked alpha-synuclein monomer was

66 of TfOH, these CF(3)-pentenynes are further intramolecularly cyclized into CF(3)-bicyclic dihydroant

67 The Ugi adducts were intramolecularly cyclized under basic conditions through

68 either re-aromatizes to give DMDIF or PsPTS1 intramolecularly cyclizes to afford (-)-maackiain.

69 Intramolecularly defined interfaces promoted the formati

70 bonds, that is, the extent to which they are intramolecularly desolvated and thereby protected from w

71 ropargyl, allyl, and alkyl alcohols has been intramolecularly displaced by uncharged O-, N-, and S-ce

72 In all cases tested, the intramolecularly disulfide bridged Ng proteins displayed

73 esis allowed for the detection of a compact, intramolecularly disulfide cross-linked oxidized hHSF1 (

74 pidly formed under oxidizing conditions, the intramolecularly disulfide-bonded species (Cys100-Cys111

75 d the resulting intermediates to be captured intramolecularly either as biradicals or as zwitterions,

76 ed the high-resolution NMR structures of two intramolecularly folded FRDA triplexes, (GAA)2T4(TTC)2T4

77 that the G-rich strand of the ILPR adopts an intramolecularly folded hairpin G-quartet structure.

78 ing studies that (C4TGTC4ACA4TGTC4) forms an intramolecularly folded hairpin with intercalated C+.C p

79 ~ 4 and low dC(20) strand concentration, an intramolecularly folded i-motif is observed, in which pr

80 ich homooligomerizable tiles are formed from intramolecularly folded RNA single strands.

81 he 17-mer favors the formation of a compact, intramolecularly folded structure dominated by two stack

82 Intramolecularly folding DNA triplexes containing altern

83 rdered self-inhibitory element that competes intramolecularly for binding with p53TAD.

84 Most cross-linking of the beta globin occurs intramolecularly, forming beta globin dimers.

85 fective in its ability to transfer electrons intramolecularly from FAD to FMN.

86 Surprisingly, GGPP is not channeled intramolecularly from the prenyltransferase to the cycla

87 One electron is then transferred intramolecularly from the reduced FMNH2 to the oxidized

88 ur-containing organic nanotubes derived from intramolecularly H-bonded helically folded aromatic fold

89 exists as a bowl, with all six substituents intramolecularly H-bonded together on one side of the pl

90 tates, and proton transfer (either inter- or intramolecularly) helps relieve excited-state antiaromat

91 The three intramolecularly homologous domains, separately cloned a

92 ions of the cumyloxyl radical (CumO(*)) with intramolecularly hydrogen bonded 2-(1-piperidinylmethyl)

93 are trans and the o-alkoxy substituents are intramolecularly hydrogen bonded to the amide NH groups.

94 lded conformation with both carboxylic acids intramolecularly hydrogen bonded to the opposing dipyrri

95 r the MR carboxylic acid proton is inter- or intramolecularly hydrogen bound.

96 ionized form of DMAPA appears to be strongly intramolecularly hydrogen-bonded and gauche in aprotic s

97 Two intramolecularly hydrogen-bonded arylhydrazone (aryl = p

98 cally less-encumbered aldehyde pi-face of an intramolecularly hydrogen-bonded chelate through a Zimme

99 ike bilirubin and mesobilirubin, 1 adopts an intramolecularly hydrogen-bonded conformation, shaped li

100 nolic linear oligomers to form "well-defined intramolecularly hydrogen-bonded conformations".

101 16, and 17, indicating that these ureas are intramolecularly hydrogen-bonded in the solid state.

102 groups in all aspirin isomers including the intramolecularly hydrogen-bonded isomers.

103 In contrast, the intramolecularly hydrogen-bonded monomers of butylene-te

104 t on amide resonances suggest the absence of intramolecularly hydrogen-bonded NH groups.

105 The Wheland intermediate is deprotonated intramolecularly in a 1,2-shift but also in a longer-ran

106 eported case, the reaction is shown to occur intramolecularly in a covalently linked system in a 77 K

107 up of the sulfonamide unexpectedly interacts intramolecularly in a pi-stacking manner with the benzim

108 te anion contact ion pairs which are trapped intramolecularly in a tandem polar/radical crossover seq

109 actions, but the individual domains interact intramolecularly in monomeric proteins, whereas they for

110 mation in which the donor strand is inserted intramolecularly in the opposite orientation relative to

111 EZH2 automethylation occurs intramolecularly (in cis) by methylation of a pseudosubs

112 nd L. polyedrum is higher than among domains intramolecularly, indicating that this unique gene struc

113 ne binding (PTB) domain that binds to APP is intramolecularly inhibited by the adjacent C-terminal li

114 Si: (9), a close model of singlet 1, inserts intramolecularly into a C-H bond of the tBu group with a

115 ulfur-nitrogen bonded radicals may transform intramolecularly into carbon-centered radicals located o

116 solubility properties, where chains collapse intramolecularly into helical conformations to minimize

117 apoptotic activity, in which the Nte inserts intramolecularly into the FimA core in the opposite, par

118 in may assist interconversion of the closed, intramolecularly ligated state and the open, active stat

119 A method for quantifying an intramolecularly linked all-d-amino acid peptide, NR58-3

120 edented post-translational modification that intramolecularly links the beta-carbon (C3) of a residue

121 prove the rigidity of spirobisindane, it was intramolecularly locked by forming eight-membered rings

122 assembling process being the formation of an intramolecularly locked conformation partly stabilized b

123 pical hydrolysis, the Hyg5 reaction proceeds intramolecularly, most likely via an arene oxide interme

124 e the corresponding singlet silylenes insert intramolecularly much faster.

125 gen bonds that are insufficiently dehydrated intramolecularly, named "dehydrons," are strategically p

126 dyad that can act both intermolecularly and intramolecularly on different molecular scaffolds exhibi

127 demonstrate that C-H activation takes place intramolecularly on the reaction coordinate between 3 an

128 Recombinant Rpg1 autophosphorylates in vitro intramolecularly only serine and threonine amino acids w

129 The benzyne can be rapidly 'trapped' either intramolecularly or intermolecularly with myriad nucleop

130 e.g., MeO) direct bond formation o,p, either intramolecularly or intermolecularly.

131 nt between the liberated head domains either intramolecularly or intermolecularly.

132 kbone atoms must form hydrogen bonds, either intramolecularly or to solvent water.

133 he catalytic cycle electrons are transferred intramolecularly over approximately 13 A from a Type 1 (

134 ere, we present the one-pot synthesis of two intramolecularly pai-stacked dimers and disclose how int

135 After this priming step, Gwl can intramolecularly phosphorylate its C-terminal tail at pS

136 Taspase1 proenzyme is intramolecularly proteolyzed generating an active 28 kDa

137 an be accomplished both intermolecularly and intramolecularly, providing useful product yields and hi

138 c fluorophores, wherein the triplet state is intramolecularly quenched by a covalently attached prote

139 le cells by fluorescence microscopy by using intramolecularly quenched casein.

140 kinin as a template, we designed a series of intramolecularly quenched fluorogenic peptide substrates

141 mine kinetic parameters and applied it to an intramolecularly quenched molecule, Pyro-PtdEtn-BHQ, a N

142 f-healing" dyes, in which triplet states are intramolecularly quenched, enable fluorescence imaging b

143 pendant hydrazine and aldehyde moieties that intramolecularly react to form hemiaminals are obtained

144 Furthermore, the DNA binding activity is intramolecularly regulated, as the N-terminus of ER71 ha

145 The intramolecularly sensitized precipiton 2Z isomerized 250

146 hylene bridge next to the fluorene moiety is intramolecularly shifted from position 2 to position 4 o

147 buted in the cytoplasm and appeared to arise intramolecularly, since no FRET was measured when mixtur

148 directing group or the reaction is conducted intramolecularly so that a specific C-H bond is favoured

149 By intramolecularly stitching together the side chains of l

150 bonds are not properly wrapped or dehydrated intramolecularly, structural integrity can be preserved

151 The resulting alpha-methoxyallene is intramolecularly substituted, leading to cyclization by

152 domain of the EGFR, it was proposed that the intramolecularly tethered and autoinhibited configuratio

153 , 134, 8513-8524), emphasizing the impact of intramolecularly tethered ArOH groups, and (b) recent ad

154 Intramolecularly, the chiral anion of an IL was found to

155 s conformation, the two SH3 domains interact intramolecularly, thereby forming the basis of an autoin

156 (2)C=C(OH)CON(+)(R)=C(R')CH(3) 5a-c, cyclize intramolecularly to 3b or undergo intermolecular additio

157 generating an isomerized olefin, or (2) add intramolecularly to a double bond, generating a cyclized

158 which also rearrange to carbodiimides or add intramolecularly to aryl substituents to yield indazoles

159 Upon photostimulation, ANQX reacts intramolecularly to form FQX or intermolecularly to form

160 tu formed acetal transfers the methoxy group intramolecularly to generate the M-S intermediate in eve

161 ions H2C=C(OH)CON+(R)=C(R')CH3 9a,b cyclize intramolecularly to give 7a,b.

162 phorylated state with the SH3 domain engaged intramolecularly to Pro1124 in the SH2-CD linker, the fo

163 urther react with hydrazoic acid and cyclize intramolecularly to provide 5-aminotetrazoles in good to

164 le bond of acrylic anhydride rapidly inserts intramolecularly to regio- and stereoselectively form a

165 The Q94 side-chain is hydrogen bonded intramolecularly to residues Y92 and S96, but amino acid

166 In fV, these epitopes may bind intramolecularly to the basic region of the B domain.

167 ch then serves as a tethered ligand, docking intramolecularly to the body of the receptor to effect s

168 mains to unmask a tethered ligand that binds intramolecularly to the body of the receptor to effect t

169 serves as a tethered peptide ligand, binding intramolecularly to the body of the receptor to effect t

170 This then binds intramolecularly to the body of the receptor to trigger

171 toacetylation, acetyl-K1596 (Ac-K1596) binds intramolecularly to the BRD, competing with histones for

172 regulates HMGB1-DNA interactions by binding intramolecularly to the DNA-binding faces of both basic

173 e assemblies are expected to transfer energy intramolecularly to the photochromic species upon excita

174 ted that this internal propeptide could bind intramolecularly to the propeptide binding site of carbo

175 motif, termed the tethered ligand that binds intramolecularly to the receptor and triggers signaling.

176 The cis-enediolate quantitatively isomerizes intramolecularly to the trans-enediolate in C6D6 at 100

177 rated in the cooperative activation step, to intramolecularly transfer its hydride to the intermediat

178 naphthalenide, in addition, one electron is intramolecularly transferred from the Si(0) atom to the

179 to generate singlet oxygen ((1)O(2)), which intramolecularly transfers to and efficiently reacts wit

180 ler-like hexatopic cpb linkers, the movement intramolecularly transmitted by the pai-pai stacking of

181 which an N-acylnitrenium ion intermediate is intramolecularly trapped by an amine group.

182 -Pr)2 to give N-acyliminium ions, which were intramolecularly trapped with oxygen, nitrogen, sulfur,

183 thyl-2-butene to generate a cyclopropane) or intramolecularly (using a biphenyl moiety at the terminu

184 S-H2](+)) rearranges to the terminal hydride intramolecularly via a low-energy pathway.

185 gy triggers the formation of a dual C-C bond intramolecularly via Lewis acid catalysis under mild rea

186 the presumed N-acylated intermediate reacts intramolecularly via nucleophilic aromatic substitution,

187 Various isoquinolinones were synthesized intramolecularly via six-membered ring formation with hi

188 nteracts with the cationic N-terminal domain intramolecularly when HTLV-1 NC is not bound to nucleic

189 ential to engage the C-Src homology 2 domain intramolecularly, which can modestly and indirectly infl

190 o functionalize all types of C(sp(3))-H bond intramolecularly, while displaying excellent chemoselect

191 The yeast Fis1p arm interacts intramolecularly with a conserved tetratricopeptide repe

192 acetal to afford an enaminone that can react intramolecularly with a phenol or intermolecularly with

193 carbonyl O, but one OH group also interacts intramolecularly with a sulfonyl O atom.

194 a single interface that can interact either intramolecularly with a terminal 'latch' helix or interm

195 Selective Cerenkov quenching was observed intramolecularly with difluorophenol red or monofluorocr

196 at in fibrinogen two alphaC-domains interact intramolecularly with each other and with the central E

197 ed into compact alphaC-domains that interact intramolecularly with each other and with the central re

198 The reaction proceeds inter- and intramolecularly with good functional group compatibilit

199 rate are removed and interchanged completely intramolecularly with inversion of configuration at the

200 enerate unsaturated amino acids, which react intramolecularly with nearby cysteines to form cyclic th

201 roquinolines in situ, which further cyclized intramolecularly with nitrogen or sulfur atom via a casc

202 3 of the product is already known to proceed intramolecularly with retention of configuration, the st

203 he cysteine-rich domain of ADAM13 cooperates intramolecularly with the ADAM13 metalloprotease domain

204 ptide aldehyde that is subsequently captured intramolecularly with the amino group of the N-terminal

205 ide evidence here that the Trio SRs interact intramolecularly with the GEF1 domain to inhibit its enz

206 gests that a phosphonate at Tyr542 interacts intramolecularly with the N-terminal SH2 domain to relie

207 larly with the ABP/GRIP linker II region and intramolecularly with the PICK1 PDZ domain.

208 ts the ability of the SH3 domain to interact intramolecularly with the SH2-kinase linker in cis as we

209 ]CPP and a bent 12H[18]CPP, which were fused intramolecularly with two and three 1,4-dimethoxybenzene

210 clease addressed in this study are performed intramolecularly within the replicating holoenzyme.