ライフサイエンスコーパス: intranuclear

1 ow macrophage precursors and that osteoclast intranuclear abundance is specifically increased by RANK

2 bination also resulted in enhanced gammaH2AX intranuclear accumulation as a result of DNA damage indu

3 ytoplasmic transport (Gle1 and RanGAP1), and intranuclear accumulation of mRNA.

4 egion-specific aggregate pathology marked by intranuclear accumulation of the mutant Atxn3 protein, a

5 tion of Wnt coreceptor LRP6 and beta-catenin intranuclear accumulation.

6 ve enabled the visualization of a variety of intranuclear activities, from chromosome dynamics to gen

7 f UBQLN2, may facilitate its action to clear intranuclear, aggregated disease proteins like HTT.

8 s progressive muscle weakness accompanied by intranuclear aggregates and TUNEL-stained nuclei in skel

9 ated PABPN1 proteins accumulate as insoluble intranuclear aggregates in muscles of OPMD patients.

10 ppUL69 localized to intranuclear aggregates that did not overlap with viral

11 solubility in the lens and forms substantial intranuclear aggregates that disrupt the denucleation pr

12 Doxy was shown to attenuate aberrant intranuclear aggregation and toxicity of misfolded prote

13 ith DUX4-induced nuclear dsRNA foci and with intranuclear aggregation of EIF4A3 and ADAR1.

14 We thus propose that intranuclear aggregation of FUS triggered by a subset of

15 ytoplasmic and nuclear ubiquitin levels, and intranuclear and cytoplasmic aggregates that were immuno

16 tingtin protein (htt), formation of neuronal intranuclear and cytoplasmic inclusions, and neuronal dy

17 bles from its partners and localizes to both intranuclear and cytoplasmic protein quality control (PQ

18 variants deficient in IPO5 binding remained intranuclear and exhibited decreased levels, which were

19 The goal of this review is to outline these intranuclear assembly steps and illustrate potential and

20 Both forms were associated with intranuclear B and C capsids, yet only the 58-kDa polype

21 These intracellular and intranuclear bacteria reside in specialized cells in sev

22 t of isoform NFATc3) and formation of NFATc1 intranuclear bodies independent of calcineurin.

23 rodlets of Roncoroni, are poorly understood intranuclear bodies originally identified within neurona

24 Although known to form distinctive intranuclear bodies, the cellular pathways and processes

25 olonged nuclear Ca(2+) transients and slowed intranuclear Ca(2+) diffusion.

26 revented nuclear mGlu5-mediated increases in intranuclear Ca2+.

27 2+)]i release was followed by an increase in intranuclear calcium and the depolarization of both the

28 During their progression from intranuclear capsids to mature trilaminar virions, herpe

29 .5 kDa, is transported to the nucleus, binds intranuclear capsids, and is converted to 58 kDa at some

30 ed that this DNA was in fact packaged within intranuclear capsids, but these capsids failed to egress

31 oscopy and Western blot analysis of purified intranuclear capsids.

32 120-kDa MCP fragment; and reduced numbers of intranuclear capsids.

33 ression of NHERF2 in sympathetic neurons (by intranuclear cDNA injections) does not affect the extent

34 ence of the ORF66 kinase, matrin 3 displayed intranuclear changes, while matrin 3 showed a pronounced

35 ral anchoring points contributing locally to intranuclear chromosome organization.

36 e mutant, RIIbeta(S114A), did not form these intranuclear clusters as well as wild-type RIIbeta, and

37 4 (pRIIbeta) and localization of pRIIbeta in intranuclear clusters.

38 comparative analyses of the internuclear and intranuclear coherence between bipolar derivations of LF

39 local field potentials in the basal ganglia, intranuclear coherence, and, thus, lateral functional co

40 storage in the nuclear envelope (NE) to the intranuclear compartment (INC), the mechanisms of Ca(2+)

41 n founder cells, Aret accumulates in a novel intranuclear compartment that we termed the Bruno body,

42 ylation of the triple serine motif regulates intranuclear compartmentalization of murine Olig2.

43 lear retention of Ctn RNA, they modulate its intranuclear compartmentalization.

44 ll nucleus and differentially associate with intranuclear compartments.

45 aled the general behavior of the nucleus and intranuclear components, direct visualization and estima

46 Intranuclear delivery of a specific antisense oligonucle

47 potential as a mediator of intracellular and intranuclear delivery of p53 for prevention and treatmen

48 suggest that peptide conjugation may enhance intranuclear delivery of reagents designed to bind to ch

49 le because of the need for intracellular and intranuclear delivery of targeting and therapeutic moiet

50 The identification of an effective intranuclear delivery vehicle and pathway for the transp

51 elivery system could boost intracellular and intranuclear delivery, thereby circumventing drug efflux

52 faces of AEC-IIs, Ms/M s, and Neus; however, intranuclear dense tubules were found only in AEC-IIs.

53 We identified virus particles and intranuclear dense tubules, which are associated with ma

54 The disease is characterized by intranuclear deposits consisting primarily of PABPN1.

55 Intranuclear diffusion of a functional c-Myc-eGFP, expre

56 e demonstrate this technique by mapping both intranuclear diffusion of NLS-GFP and recovery of 53BP1-

57 as9-sgRNAs, it was possible to determine the intranuclear distance between loci on different chromoso

58 o acid substitution (Cys19Gly) alters ORF61p intranuclear distribution and abolishes ORF61p-mediated

59 as no detectable effect on nuclear import or intranuclear distribution of hsTAF5 and hsTAF12.

60 challenged with 100-200 mm sorbitol, and the intranuclear distribution of nucleolin was monitored by

61 thesis centered on nucleoli: the specialized intranuclear domains within which ribosomes are assemble

62 NA) response pathway and the accumulation of intranuclear dsRNA foci.

63 nd performed a comprehensive analysis on the intranuclear dwell times of four steroid receptors and a

64 ase has indicated an unanticipated degree of intranuclear dynamics of both its RNA and protein subuni

65 the mechanism of this resistance, we studied intranuclear dynamics of hVDR and hRXRalpha-tagged const

66 ng protein-5 (IGFBP-5) has IGF-1-independent intranuclear effects that are poorly defined.

67 he mechanisms whereby IGFBP-5 and FLNa exert intranuclear effects.

68 used as a biophysical strategy to probe the intranuclear environment.

69 r regulation of gene transcription and other intranuclear events.

70 Intranuclear expression of SOX2 marks the clonogenic CD1

71 ely, activate cell surface FGF receptors and intranuclear FGFR1, to determine the roles of membrane F

72 ncoding full-length NSs completely abrogated intranuclear filament formation in infected cells.

73 t virus encoding the NSs core domain induced intranuclear filaments, suggesting it contains all essen

74 nvolved in retaining cellular transcripts in intranuclear foci and can regulate the export of mRNA to

75 rts differential effects on the formation of intranuclear foci by ATR and replication protein A, impl

76 e abnormalities and induced the formation of intranuclear foci in the primary keratinocytes expressin

77 at ATRIP is required for ATR accumulation at intranuclear foci induced by DNA damage.

78 demonstrated abnormal nuclear envelopes with intranuclear foci of lamins in cardiac cells expressing

79 lamina at prophase, and also transiently to intranuclear foci.

80 ng to ATR and localization to damage-induced intranuclear foci.

81 erinucleolar sites associated with lamin A/C intranuclear foci.

82 linked and unlinked, coalesce into discrete intranuclear foci.

83 us Nup98 that lead to mislocalization of the intranuclear fraction of Nup98, but do not alter the lev

84 Intranuclear free Zn(2+) sparks caused by reactive oxyge

85 transfer, and we found that the formation of intranuclear Gag complexes was dependent on the NC domai

86 In FIV-infected feline cells, some intranuclear Gag was detected in the steady state withou

87 entation allowed the direct visualization of intranuclear Gag-Gag dimers.

88 Intranuclear gamma-crystallin aggregates, incomplete den

89 SMN protein levels and intranuclear gems also were significantly increased in t

90 Most occur in conjunction with intranuclear genomic rearrangements, and the features of

91 2 ALS patients revealed disease-specific (1) intranuclear GGGGCCexp RNA foci, (2) dysregulated gene e

92 nuclear O(2)(.-) production, suggesting that intranuclear glucose-6-phosphate dehydrogenase (G6PD) ca

93 earts was essential for targeting RyR2 to an intranuclear Golgi apparatus and promoted the intracellu

94 matin in mouse cells and sites of DAPI-dense intranuclear heterochromatin in human and hamster cells

95 Mitotic cells have a distinctive intranuclear heterochromatin-free "spindle tunnel" with

96 Restoration of intranuclear HIF-1alpha to these areas was achieved by h

97 al DNA, which would obscure the detection of intranuclear HIV-1 genomes.

98 inucleotide binding permits CtBP1 to form an intranuclear homodimer through a Trp(318) switch, creati

99 ntage of htt-positive nuclei and the size of intranuclear htt aggregates were reduced by the CaM-frag

100 n-containing interneurons, inflammation, and intranuclear huntingtin aggregates.

101 Hand2 is developmentally regulated and is intranuclear in precursors but cytoplasmic in neurons.

102 lly leading to deposition of cytoplasmic and intranuclear inclusion bodies containing htt.

103 pithelium and ballooning degeneration of and intranuclear inclusion bodies in epithelial cells, with

104 duct A or 1 (cp-A/1), form intracellular and intranuclear inclusion bodies in the brains of patients

105 c of pan-cellular HD mouse models, including intranuclear inclusion bodies, motor impairment, and cha

106 vealed intranuclear inclusions suggestive of intranuclear inclusion body disease (NIID).

107 Striatal neuronal intranuclear inclusion burden was similar between HD kno

108 Neuronal intranuclear inclusion disease (NIID) is a slowly progre

109 , nuclear mutant huntingtin accumulation and intranuclear inclusion formation.

110 hallmark of FXTAS is the ubiquitin-positive intranuclear inclusion found in neurons and astrocytes i

111 he neuropathological hallmark of FXTAS is an intranuclear inclusion, present in both neurons and astr

112 colytic fibres, containing a large number of intranuclear inclusions (INIs).

113 arly as 9 weeks of age and striatal neuronal intranuclear inclusions (NIIs) by 20 weeks.

114 Neuronal intranuclear inclusions (NIIs) characteristically occur.

115 other than widespread ubiquitinated neuronal intranuclear inclusions (NIIs).

116 l dysregulation and accumulation of neuronal intranuclear inclusions (NIIs).

117 ed extensively convoluted nuclear envelopes, intranuclear inclusions and chromatin clumps in cardiomy

118 ve neuronal cytoplasmic inclusions, neuronal intranuclear inclusions and neurites were recorded and f

119 hole mount immunohistochemistry, to identify intranuclear inclusions and quantify subsets of enteric

120 Formation of fibrillar intranuclear inclusions and related neuropathologies of

121 hich is found in the neuronal and astrocytic intranuclear inclusions associated with the disorder.

122 ation) CGG repeat, we have demonstrated that intranuclear inclusions can be formed in both primary ne

123 ure death that are characterized by abnormal intranuclear inclusions composed of TDP-43 and fused in

124 Whether intranuclear inclusions containing DNA damage response (

125 Ubiquitin-positive intranuclear inclusions have also been found in the neur

126 Intranuclear inclusions have also been reported in the n

127 FTLD with ubiquitin-positive cytoplasmic and intranuclear inclusions in all PGRN mutation carriers.

128 ds to determine the pathological features of intranuclear inclusions in astroglia and neurons.

129 ebral white matter and (iii) the presence of intranuclear inclusions in both brain and spinal cord.

130 the number of CGG repeats and the numbers of intranuclear inclusions in both neurons and astrocytes,

131 1C2-positive intranuclear inclusions in cerebellar Purkinje and brain

132 The morphology of intranuclear inclusions in CGG KI mice was compared to t

133 st time, de novo formation of ChHV5-positive intranuclear inclusions in cultured green turtle cells,

134 complete striatal degeneration and rarity of intranuclear inclusions in HD, and the fact that mice ex

135 rectly relevant to the formation of neuronal intranuclear inclusions in Huntington's disease.

136 a syndrome typically have cerebellar ataxia, intranuclear inclusions in neurons and astrocytes, as we

137 allmark of the disease is ubiquitin-positive intranuclear inclusions in neurons and astrocytes.

138 isease is the presence of ubiquitin-positive intranuclear inclusions in neurons and in astrocytes.

139 FXTAS is the presence of ubiquitin-positive intranuclear inclusions in neurons and in astroglia.

140 The models exhibit the presence of intranuclear inclusions in Purkinje neurons, Purkinje ne

141 tion of FUS but facilitated the formation of intranuclear inclusions in rat hippocampal neurons with

142 logy and by the late development of neuronal intranuclear inclusions in spinal neurons.

143 rative disease characterized by eosinophilic intranuclear inclusions in the nervous system and multip

144 que pathological feature - appearance of the intranuclear inclusions in the neurons and astrocytes, i

145 , and in some familial cases UBQ-ir neuronal intranuclear inclusions of a lentiform appearance.

146 is impaired, even prior to the formation of intranuclear inclusions of aggregated AR.

147 omedullary junction and skin biopsy revealed intranuclear inclusions suggestive of intranuclear inclu

148 Ubiquitin-positive intranuclear inclusions were also present in protoplasmi

149 clear mutant huntingtin and the formation of intranuclear inclusions were fastest in the C57BL/6 back

150 In CGG KI mice, ubiquitin-positive intranuclear inclusions were found in neurons (e.g., pyr

151 In female CGG KI mice, ubiquitin-positive intranuclear inclusions were found in neurons and astrog

152 in sarcoma-positive neuronal cytoplasmic and intranuclear inclusions were found in the hippocampal gr

153 ere distinct and temporally dissociated from intranuclear inclusions, and disappeared rapidly after c

154 mmunolocalized to both nuclear membranes and intranuclear inclusions, fluorescent detection of NADPH-

155 o induce the formation of ubiquitin-positive intranuclear inclusions, which also stain positive for t

156 ne tract that is misfolded and prone to form intranuclear inclusions, which are the hallmark of the d

157 l neurons contained ubiquitin-immunoreactive intranuclear inclusions.

158 both grey and white matter and also neuronal intranuclear inclusions.

159 icularly visceral neuropathies with neuronal intranuclear inclusions.

160 rs, including some characterized by neuronal intranuclear inclusions.

161 ith alterations in the formation of neuronal intranuclear inclusions.

162 eristic lentiform ub-immunoreactive neuronal intranuclear inclusions.

163 e, particularly in those cases with neuronal intranuclear inclusions.

164 gender-specific motor deficits, and neuronal intranuclear inclusions.

165 the proteasome after it is incorporated into intranuclear inclusions.

166 r neuron loss, with polyQ-AR accumulation in intranuclear inclusions.

167 athway by which this occurs involves direct, intranuclear interaction of the photoactivated phy molec

168 ved N-terminal region of pUL50 determine its intranuclear interaction with pUL53.

169 During interphase, the lamins form an intranuclear intermediate filament network that must be

170 canceri's adaptation to intranuclear life is underpinned by the expansion of tra

171 tive VLDL secretion and steatosis, including intranuclear lipid accumulation.

172 cognition motifs) drove TDP-43 demixing into intranuclear liquid spherical shells with liquid cores.

173 ered that mutant Nna1 dramatically increases intranuclear localization of lysyl oxidase propeptide, w

174 on of oxidative stress markers, and enhanced intranuclear localization of pancreatic and duodenal hom

175 ic evidence demonstrates the requirement for intranuclear localization of regulatory complexes that f

176 we show an explicit relationship between the intranuclear localization of various chromosome segments

177 an aberrant Ad E2 DNA-binding protein (DBP) intranuclear localization pattern and an apparent failur

178 This intranuclear localization remains throughout adulthood a

179 shown in cells by coimmunoprecipitation, and intranuclear localization studies using confocal microsc

180 ingle amino acid substitution that abrogates intranuclear localization was introduced in the AML1 sub

181 It controls the intranuclear localization, stability, and DNA repair fun

182 The intranuclear location of genomic loci and the dynamics o

183 of this segregation by modulating either the intranuclear location of the MyoD gene or TAF3 protein l

184 SCARNA97 despite their apparently different intranuclear locations.

185 secretion) and phenotypic (cell surface and intranuclear) markers were assessed using flow cytometry

186 ogenesis, composition, and function of these intranuclear membrane cisternae are unknown.

187 are sufficient to traffic fusion proteins to intranuclear membranes and the ODV envelope during infec

188 ects in cell division and a proliferation of intranuclear membranes derived from the nuclear envelope

189 then is incorporated into the virus-induced intranuclear membranes.

190 um to the nuclear envelope and viral-induced intranuclear membranes.

191 action of cells with diffuse, perinuclear or intranuclear mHTT changed in parallel with decreasing mo

192 receptor that registers BMP signaling as the intranuclear migration of Smad2, and as the transcriptio

193 Mod20p is not required for intranuclear mitotic spindle assembly, although it is re

194 tubule nucleation ceases simultaneously with intranuclear mitotic spindle assembly.

195 n of AML1 with ETO or MTG16 exhibits reduced intranuclear mobility compared with wild-type AML1 or ei

196 own that PAX5-PML fusion protein has reduced intranuclear mobility compared with wild-type PAX5.

197 ting prolonged nuclear retention and reduced intranuclear mobility especially following ligand stimul

198 By measuring the abundance and intranuclear mobility of an upstream transcription facto

199 Furthermore, although the intranuclear mobility of GFP-Stat3alpha was rapid and in

200 and increased with cytokine stimulation, the intranuclear mobility of GFP-Stat3beta in unstimulated c

201 (CC) of PML was responsible for the reduced intranuclear mobility of PAX5-PML.

202 Prolonged nuclear retention, but not reduced intranuclear mobility, mapped to the CT7 domain of Stat3

203 nged nuclear retention but did not alter its intranuclear mobility.

204 s U1-small nuclear RNA is a highly conserved intranuclear molecular complex involved in splicing pre-

205 d at NaCl concentrations within the reported intranuclear monovalent cation concentration range, and

206 l stimulation: an initial event of increased intranuclear movement followed by a regime of intranucle

207 The role of the intranuclear movement of chromatin in gene expression is

208 ntranuclear movement followed by a regime of intranuclear movements that reflect the dose of applied

209 Thus, applied extracellular forces stimulate intranuclear movements, resulting in repositioning of nu

210 cytoplasmic MTs arise from spindle or other intranuclear MTs that exit the nucleus.

211 e 85 years; microscopic examination revealed intranuclear neuronal and astrocytic inclusions, in acco

212 FXTAS is characterized by ubiquitin-positive intranuclear neuronal inclusions, raising the possibilit

213 e T cells lacking CCR5 had reduced levels of intranuclear NFAT following activation.

214 Intranuclear nuclear factor kappaB (NF-kappaB) binding a

215 mutant-infected cells showed the presence of intranuclear nucleocapsids and the absence of cytoplasmi

216 cation of the DExH/D-box helicase DHX9 as an intranuclear Nup98 binding partner.

217 The RNA binding protein TDP-43 forms intranuclear or cytoplasmic aggregates in age-related ne

218 We found that the intranuclear organization and nucleosome interactions of

219 Our findings suggest that fidelity of Runx2 intranuclear organization is necessary for expression of

220 Correct intranuclear organization of chromosomes is crucial for

221 e nucleolus, possibly to avoid disruption of intranuclear organization.

222 Intranuclear p21 accumulates in Pttg-null aneuploid GH-s

223 crosporidium saccamoebae [Rozellomycota], an intranuclear parasite of amoebae.

224 y immunoblotting and increased the number of intranuclear particles called gems.

225 ese data suggest that an initial step in the intranuclear path of some mRNAs is passage from the gene

226 eby ebselen prevents apoptosis and preserves intranuclear Pdx-1 and MafA, which, in turn, is a likely

227 ced hydrolysis of nuclear PI(4,5)P(2) by the intranuclear PLCdelta4, rather than by PLCgamma1.

228 This in turn creates intranuclear polarity in emerin, and thereby controls nu

229 posite strand, ATXN8OS) and the discovery of intranuclear polyglutamine inclusions suggests SCA8 path

230 ection is established by the formation of an intranuclear pool of covalently closed circular DNA (ccc

231 ther our data uncover a previously neglected intranuclear pool of the Y-complex that may underscore a

232 The intranuclear position of many genes has been correlated

233 pendent transcription was independent of the intranuclear position of the gene, but the nucleolar rec

234 summary, TFIIIC and Mps3 together direct the intranuclear positioning of a new class of S. cerevisiae

235 onferred by the HD is critical for the final intranuclear positioning of the metastable complex.

236 ot recruit RNA polymerase III, show specific intranuclear positioning.

237 We used live-cell imaging to determine the intranuclear positions of 13 Pol III-transcribed genes.

238 We determined intranuclear positions of 15 loci distributed every ~100

239 Accordingly, we examined whether the intranuclear positions of Bdnf and Trkb genes, encoding

240 Considering that perturbed intranuclear pre-tRNA metabolism and apparent deficiency

241 anization, rupture because of an increase in intranuclear pressure from actin-based nucleus confineme

242 tingly, the Q129H mutation severely impaired intranuclear processing of progeny virions compared to t

243 These findings suggest that MLL5 forms intranuclear protein complexes that may play an importan

244 , full-length interleukin-33 (FLIL33), is an intranuclear protein in many cell types, including fibro

245 g et al. now show that it is organized by an intranuclear protein, UAP56.

246 (CCT) and 25 other proteins--define a novel intranuclear quality control compartment (INQ) that sequ

247 a framework of how different signals affect intranuclear redistribution, posttranslational modificat

248 of HSATII transcripts depleted DUX4-induced intranuclear ribonucleoprotein aggregates and decreased

249 ORF72 ALS/FTD, including sense and antisense intranuclear RNA foci and poly(glycine-proline) dipeptid

250 Arg mutation, which resulted in reduction of intranuclear RNA-binding proteins.

251 Intranuclear rod myopathy is a subtype of NM in which ro

252 iated with NM, only ACTA1 is associated with intranuclear rod myopathy.

253 Intranuclear rodlets (INRs), also known as rodlets of Ro

254 mild NM, especially when cardiac problems or intranuclear rods are present.

255 spiratory function, cardiac involvement, and intranuclear rods in biopsied muscle were observed in tw

256 his study suggests that nesprin-2 is a novel intranuclear scaffold, essential for nuclear ERK1/2 sign

257 Strikingly, RNAi-mediated knockdown of intranuclear Sec13 and Nup98 specifically inhibits trans

258 We suggest that intranuclear sequestration of core transcription compone

259 cccDNA probe set was confirmed by its strict intranuclear signal and by a series of Southern blot ana

260 Intranuclear single-chain uPA binds directly to and inte

261 hat the two proteins partially colocalize at intranuclear sites in iEBHX1S-4 cells.

262 -encoded COX subunit genes all occupy common intranuclear sites in the murine neuronal nuclei.

263 ntial components of telomerase accumulate at intranuclear sites separate from telomeres.

264 rget green fluorescent protein and emerin to intranuclear sites that contained the UL31 protein.

265 perhaps differentially regulated at various intranuclear sites, may be a major determinant of nuclea

266 pon light exposure, PIF7 rapidly migrates to intranuclear speckles, where it colocalizes with phyB.

267 h pAPP epitopes and with expressed Cgamma at intranuclear speckles.

268 Z(K178D) localized to the periphery of large intranuclear spheres, to discrete nuclear aggregates, an

269 ebp1c, Chrebp, Lpk, Dgat, Fasn and Scd1, and intranuclear SREBP1c and ChREBP.

270 turation was also delayed, evident as strong intranuclear staining and little virus at the mucosa.

271 Autoantibody function was assessed by intranuclear staining for GM-CSF-induced STAT5 phosphory

272 XP3(-) ex-Treg by applying a newly developed intranuclear staining protocol that permits the isolatio

273 ng for intracellular cytokine production and intranuclear STAT5 phosphorylation.

274 in the cleavage bodies, which are a kind of intranuclear structure.

275 ies revealed its dynamic localization within intranuclear structures known as GLFG bodies.

276 type-specific expression of these enigmatic intranuclear structures.

277 d electron microscopic studies that revealed intranuclear sun-shaped capsid factories, tubules, vario

278 alamocortical system is regulated in part by intranuclear synaptic inhibition within the reticular nu

279 The compromised intranuclear targeting of regulatory proteins under path

280 une receptors across the nuclear envelope to intranuclear targets.

281 sue, Jady et al. place the Cajal body on the intranuclear traffic route of telomerase RNA.

282 t the trans-acting factors important for the intranuclear trafficking and nucleolar localization of s

283 GLI1 intranuclear trafficking by LAP2 isoforms represents a p

284 that telomerase activity may be regulated by intranuclear trafficking of the key components of the en

285 viral NS1 protein and cellular factors to an intranuclear trafficking pathway that targets the viral

286 viral NS1 protein and cellular factors to an intranuclear trafficking pathway that targets the viral

287 d connects HIV-1 preintegration complexes to intranuclear trafficking pathways that link integration

288 type (CD28, CD127) memory subset markers and intranuclear transcription factors, as well as functiona

289 Regulation of gene expression by intranuclear transduction of macromolecules such as tran

290 icroscopy of VZV-infected cells demonstrated intranuclear translocation of the Mediator complex to vi

291 e found that in the absence of calreticulin, intranuclear transport of NFATC1 is blocked and that dif

292 is inconsistent with a role in micron-scale intranuclear transport, and their localization suggests

293 ing transcription, chromatin remodeling, and intranuclear transport.

294 for immunohistochemistry had cytoplasmic and intranuclear ubiquitin positive, tau negative inclusions

295 Intranuclear uPA modulates gene transcription by binding

296 tion on TF binding, chromatin accessibility, intranuclear variation in local TF concentration, and ra

297 y robust while preserving the observation of intranuclear variations of mobility.

298 e relationships in mammalian cells including intranuclear vesicles containing endoplasmic reticulum-a

299 litis in control and knockout mice; however, intranuclear viral inclusions were seen only in Il1r1(-/

300 Virtually all FIV Gag rapidly became intranuclear when the CRM1 export pathway was blocked, i