ライフサイエンスコーパス: intratracheal

1 ient mice received 2.5 g/kg of LPS or saline intratracheal.

2 Furthermore, intratracheal administration of Ad-Stat3-EVA caused sign

3 odynamically, and animals were randomized to intratracheal administration of aerosolized AAV1 carryin

4 e to mainstream CS increases AHR after acute intratracheal administration of Aspergillus fumigatus ex

5 A single intratracheal administration of CCL21 gene-modified dend

6 ved in antibacterial defenses, and exogenous intratracheal administration of CG combined with NE does

7 In anesthetized guinea pigs intratracheal administration of DEPs activated airway C-

8 Intratracheal administration of GM-CSF induced final rAM

9 Intratracheal administration of IL-17 provoked a neutrop

10 In initial studies, we found that the intratracheal administration of Klebsiella pneumoniae in

11 Methods: ALI was induced by a single intratracheal administration of lipopolysaccharide (10,

12 Lung injury was induced by intratracheal administration of lipopolysaccharide (5 mg

13 Lung inflammation was induced with intratracheal administration of lipopolysaccharide (LPS)

14 gs) in mouse lung experimentally inflamed by intratracheal administration of lipopolysaccharide.

15 Depletion of macrophages by the intratracheal administration of liposomal clodronate att

16 In this study, we report that intratracheal administration of LMW HA (200 kDa) causes

17 Intratracheal administration of low molecular mass (LMM)

18 Intratracheal administration of LPS (1 mg/kg) in WT mice

19 lation of neuraminidase (NA) 30 min prior to intratracheal administration of LPS increased polymorpho

20 Intratracheal administration of ManLAM in mice resulted

21 ction could be achieved in the lung from the intratracheal administration of mRNA.

22 bited augmented clearance 3 and 7 days after intratracheal administration of P. murina, which correla

23 Intratracheal administration of recombinant mouse comple

24 Intratracheal administration of rmCIRP into WT mice sign

25 nhibition of Fas gene expression in lungs by intratracheal administration of small interfering RNA co

26 Intratracheal administration of SP-A to SP-A(-/-) mice e

27 Intratracheal administration of Sph3h was well tolerated

28 n and widespread lung distribution following intratracheal administration of the formulations.

29 y drug accumulation in lungs and blood after intratracheal administration of the spray dried inhalabl

30 Intratracheal administration of this vector delivering m

31 rachea of wild-type and Cxcr2(-/-) mice, but intratracheal administration of TNFalpha did not induce

32 Intratracheal administration of Wnt3a or an antibody cap

33 Their intratracheal administration resulted in increased airwa

34 % lower in Abcc1 ((-/-)) rats, whereas after intratracheal administration, AUC(lung) was 352% higher

35 Following intratracheal administration, OVA-specific CD4(+)CD25(+)

36 mor tissues persisted at least 14 days after intratracheal administration.

37 mor-targeted gene delivery in the setting of intratracheal administration.

38 ion, specifically in the upper airways after intratracheal administration.

39 vivo models in two species via intranasal or intratracheal administration.

40 profile with no signs of toxicity following intratracheal administration.

41 drive neutrophilic airways inflammation upon intratracheal adoptive cell transfer into congenic mice.

42 ase was produced in all animals following an intratracheal aerosol of 10(4) CFU delivered, with varia

43 inistration of (11)C-BMP intravenously or by intratracheal aerosolization.

44 term lambs were randomly assigned to receive intratracheal aerosolized surfactant or bolus surfactant

45 SPDEF was induced following intratracheal allergen exposure and after Th2 cytokine s

46 ifferent routes, by intracerebroventricular, intratracheal, and intraperitoneal injections.

47 Intratracheal anti-MHC class I Abs or hydrochloric acid

48 ockout (Rag2(-/-)) mice by means of repeated intratracheal applications of SplD.

49 ramin+RB2) or TXA2 receptor (SQ29548), or by intratracheal apyrase.

50 ignificantly higher mortality in response to intratracheal bacterial challenge.

51 erium tuberculosis strain was established by intratracheal bacterial instillation followed by proper

52 Mice were given intratracheal bleomycin (0.04 units) and assessed for AE

53 ility to exacerbate lung scarring induced by intratracheal bleomycin administration.

54 in two models of pulmonary fibrosis in mice (intratracheal bleomycin and inducible TGF-beta1).

55 Of note, lung fibrosis induced after intratracheal bleomycin challenge in mice could be preve

56 (+)CD25(hi)Foxp3(+) cells in the lung during intratracheal bleomycin challenge; however, this unexpec

57 Intratracheal bleomycin exposure results in substantial

58 ly) daily for 7 days beginning 10 days after intratracheal bleomycin had improved survival over contr

59 two different models of pulmonary fibrosis, intratracheal bleomycin instillation and thoracic irradi

60 decreases lung hydroxyproline content after intratracheal bleomycin to levels comparable with that o

61 After intratracheal bleomycin, L188Q SFTPC-expressing mice dev

62 protected from pulmonary fibrosis induced by intratracheal bleomycin, with minimal alterations in the

63 Cs) in draining lymph nodes was inhibited by intratracheal but not intraperitoneal delivery of AAL-R.

64 Intratracheal, but not i.v., administration of naive lun

65 and 10 mg/kg, respectively), intubated using intratracheal cannula, and ventilated (9 mL/kg, 150 min)

66 Intratracheal cardiolipin administration in mice recapit

67 Intratracheal challenge of transgenic mice with Gram-pos

68 Mice that undergo i.p. sensitization and intratracheal challenge with 10(6) S. chartarum spores d

69 ctin-1 (Dectin-1(-/-)) are more sensitive to intratracheal challenge with A. fumigatus than control m

70 r challenge with lipopolysaccharide (LPS) or intratracheal challenge with Escherichia coli.

71 Intratracheal challenge with Haemophilus influenza enhan

72 impaired pulmonary bacterial clearance after intratracheal challenge with Klebsiella pneumoniae.

73 ed the responses of BALB/c mice following an intratracheal challenge with S. pneumoniae after 5 weeks

74 anced pulmonary bacterial clearance after an intratracheal challenge with Streptococcus pneumoniae.

75 d in sterilizing immunity upon an aggressive intratracheal challenge with the 2009 H1N1 pandemic viru

76 Using a validated mouse model of intratracheal challenge, we investigated the role of TLR

77 Intratracheal coadministration of IL-17A and TNF-alpha i

78 eal and to a lesser extent intramuscular and intratracheal deliveries led to trafficking of mRNA-LNPs

79 particle structure-function relationships on intratracheal delivery and related biodistribution and p

80 Transduction efficacy after intratracheal delivery of AAV1 was confirmed by beta-gal

81 stablished PAH, gene transfer of SERCA2a via intratracheal delivery of aerosolized adeno-associated v

82 Intratracheal delivery of aerosolized monoclonal antibod

83 rast, resident macrophage depletion from the intratracheal delivery of clodronate liposomes enhanced

84 nflammation, injury, and mortality following intratracheal delivery of Escherichia coli LPS.

85 Intratracheal delivery of stem cells into injured or dis

86 In this report, we show that intratracheal delivery of the chiral sphingosine analog

87 Intratracheal delivery of water-soluble S1P(1) receptor

88 vaccine was delivered by both intranasal and intratracheal delivery than when it was delivered intran

89 lergic airway inflammation received a single intratracheal dose of ovalbumin (OVA), 2 days after the

90 el in A/J mice, on day 60 following a single intratracheal dose with or without single intravenous pa

91 onal microparticles on day 21 after a single intratracheal dosing of dry powders in A/J mice.

92 pressor transgene overexpression or sham and intratracheal E. coli inoculation, rats underwent 4 hour

93 (100 mg/m(3) total particulate matter) or by intratracheal elastase injection.

94 A second group was treated with intratracheal elastase to induce emphysema.

95 In a mouse model of intratracheal endotoxin-induced alveolitis, coexposure t

96 isplayed augmented inflammatory responses to intratracheal endotoxin.

97 LPS; 5 mg/kg of body weight) was followed by intratracheal Escherichia coli (10(6) CFU) in wild-type

98 In animals (n = 142) administered intratracheal Escherichia coli challenge, compared to pl

99 onomicrobial pulmonary infection by using an intratracheal Escherichia coli infection model of pneumo

100 We observed that repeated intratracheal exposure to SplD led to IL-33 and eotaxin

101 HO-1 induction inhibited PMC migration after intratracheal fibrogenic injury.

102 tory epithelial permeability, as revealed by intratracheal FITC-dextran tracking, serum Club Cell pro

103 n apoptosis was noted in the lungs following intratracheal flu infection of iNOS knockout mice.

104 erimental pneumonia caused by L. pneumophila Intratracheal (i.t.) administration of L. pneumophila in

105 In initial studies, we found that the intratracheal (i.t.) administration of L. pneumophila to

106 model of pulmonary LPS tolerance induced by intratracheal (i.t.) administration of LPS.

107 s (s.c.) administration of c-di-GMP prior to intratracheal (i.t.) challenge with Klebsiella pneumonia

108 CBA/J mice were highly susceptible to intratracheal (i.t.) Cryptococcus neoformans infection r

109 An intratracheal (i.t.) injection of bacterial LPS caused i

110 As a model of ALI, we administered intratracheal (i.t.) LPS to mice and observed peak lung

111 Compared with mice given intratracheal IL-13 alone, those exposed to IL-13 and IL

112 Intratracheal IL-33 challenge resulted in decreased C5aR

113 osinophilic lung inflammation in response to intratracheal IL-4 and exogenous histamine restores resp

114 Intratracheal immunization with a higher dose of a heter

115 odel, pili were critically important with an intratracheal infection model.

116 Intratracheal infection of cynomolgus macaques with thes

117 Intratracheal infection of Syrian hamsters with Ad14p1 c

118 ges and less inflammation in the lungs after intratracheal infection than control mice.

119 in in the pulmonary vasculature following an intratracheal infection with a systemic viral pathogen.

120 n of K-Ras(G12V) expression in lung cells by intratracheal infection with adenoviral-Cre particles ge

121 survival compared with wild-type mice after intratracheal infection with K. pneumoniae.

122 double-knockout mice were studied following intratracheal infection with VV, VVDeltaK3L, or VVDeltaE

123 o the airways of naive wild-type mice before intratracheal inhalation of GC frass resulted in signifi

124 ve BALB/c mice were challenged with a single intratracheal inhalation of GC frass.

125 t, BALB/c mice were challenged with a single intratracheal inhalation of Hsp72 and killed 4 h later.

126 This potentiating effect was rescued by intratracheal injection of apyrase.

127 increased on day 7, 14, and 21 after single intratracheal injection of bleomycin (BLM).

128 Using intratracheal injection of bleomycin or hydrochloric aci

129 Intratracheal injection of crocidolite asbestos in mice

130 Both groups of mice then underwent intratracheal injection of either Pseudomonas aeruginosa

131 in the model of acute lung injury caused by intratracheal injection of LPS.

132 Intratracheal injection of PLY caused lethal acute lung

133 of palpable tumors, all animals received an intratracheal injection of Pseudomonas aeruginosa.

134 Intratracheal injection of S. mucilaginosus in C57BL/6 m

135 ophil response in G-CSFR(-/-) mice following intratracheal injection with Pseudomonas aeruginosa-lade

136 muL of sterile saline was delivered through intratracheal injection.

137 pulmonary pathogen Pseudomonas aeruginosa by intratracheal injection.

138 Conventional intratracheal inoculation of a liquid suspension of H5N1

139 allergic bronchopulmonary mycosis following intratracheal inoculation of Cryptococcus neoformans 240

140 model of pulmonary cryptococcosis induced by intratracheal inoculation of Cryptococcus neoformans.

141 A single intranasal/intratracheal inoculation of juvenile baboons with BPZE1

142 Likewise, after intratracheal inoculation of Naip5+ mice, the yield of L

143 olized bacteria, the rat model has relied on intratracheal inoculation of organisms because of safety

144 We hypothesized that intratracheal inoculation of rats with a USA300 CA-MRSA

145 bility to infect the lungs of A/J mice after intratracheal inoculation, indicating that legiobactin i

146 recovered only from nasal epithelium; after intratracheal inoculation, it was recovered also from tr

147 enovirus primed a response to the subsequent intratracheal inoculation, suggesting a route to optimiz

148 er virus titers in the nasal turbinates than intratracheal inoculation.

149 hesus macaques as a model for MERS-CoV using intratracheal inoculation.

150 in the African green monkey (AGM) following intratracheal inoculation.

151 cruitment of neutrophils to the lung on D-DT intratracheal installation of C57BL/6J mice with an EC50

152 ted eosinophilic inflammation in response to intratracheal installation of IL-13.

153 th pCB delivered through intubation-assisted intratracheal instillation (IAIS) into the lung exhibite

154 Intratracheal instillation (IT) of the aqueous extracts

155 ley (SD) or Fisher 344 (F344) rats following intratracheal instillation (IT).

156 neutrophils with purified vitronectin before intratracheal instillation decreased efferocytosis in vi

157 ther group of C57BL/6J mice received IL-4 by intratracheal instillation for 7 days.

158 en proposed as a useful alternative to rapid intratracheal instillation for the delivery of exogenous

159 se of paclitaxel by up to 100-fold following intratracheal instillation in healthy mice.

160 odistribution and elimination pathways after intratracheal instillation in mice.

161 showed a surprisingly short retention after intratracheal instillation in rat lungs, and incorporati

162 , in vivo augmentation of lung ceramides via intratracheal instillation in rats significantly decreas

163 Following intratracheal instillation into naive mice, PS50G were p

164 Importantly, intratracheal instillation of 8-pCPT-cGMP in BALB/c mice

165 Intratracheal instillation of a lethal dose of ricin (20

166 y enhanced its anti-tumor efficacy following intratracheal instillation of a single dose in a Lewis l

167 g in human neutrophils and demonstrated that intratracheal instillation of a TAT-conjugated PKCdelta

168 ach, the secondary challenge was replaced by intratracheal instillation of allergen-pulsed bone marro

169 Intratracheal instillation of anti-MHC class I Abs, but

170 Intratracheal instillation of apoptotic cells enhances r

171 -type or EC-SOD-null mice were exposed to an intratracheal instillation of asbestos or bleomycin.

172 ne model of pulmonary fibrosis induced by an intratracheal instillation of bleomycin (control mice we

173 To investigate this issue, we used intratracheal instillation of bleomycin as a model of ac

174 s induced in female C57BL/6 mice by a single intratracheal instillation of bleomycin.

175 development of pulmonary fibrosis after the intratracheal instillation of bleomycin.

176 Rats were colonized by intratracheal instillation of Candida albicans.

177 on or i.p. administration of live E. coli or intratracheal instillation of carrageenan plus myelopero

178 The single intratracheal instillation of caspase-3 siRNA not only a

179 ory distress syndrome was induced in rats by intratracheal instillation of E. coli (1.5-2 x 10 CFU/kg

180 Intratracheal instillation of either lipid caused substa

181 Intratracheal instillation of endotoxin-free HA (25 mug)

182 Intratracheal instillation of endotoxin-free low molecul

183 We treated wild-type (WT) and mCAT mice with intratracheal instillation of Escherichia coli LPS and f

184 In addition, intratracheal instillation of IL-36alpha enhanced mRNA e

185 e day postburn, some of the animals received intratracheal instillation of Klebsiella pneumoniae and

186 Intratracheal instillation of L-selectin-deficient (L-Se

187 Intratracheal instillation of leptin at a dose that was

188 Wild-type or tlr4 mice were challenged by intratracheal instillation of lipopolysaccharide (0.3 mg

189 Moreover, intratracheal instillation of lipopolysaccharide induced

190 long-term macrophage depletion by repetitive intratracheal instillation of liposomal clodronate.

191 One h after intratracheal instillation of liposomal fasudil, mean pu

192 Intratracheal instillation of low concentrations of aden

193 g ECs freshly isolated from mice showed that intratracheal instillation of LPS induced ROCK activatio

194 However, intratracheal instillation of LPS resulted in accelerate

195 After intratracheal instillation of LPS, ROS generation was im

196 als overexpressing Activin-A or treated with intratracheal instillation of LPS.

197 her by ectopic expression of Activin-A or by intratracheal instillation of LPS.

198 Intratracheal instillation of neuraminidase (NA) 30 min

199 ung neutrophils were isolated 24 hours after intratracheal instillation of PBS or S. pneumoniae, and

200 Similarly, intratracheal instillation of PGD(2) enhanced removal of

201 Intratracheal instillation of PLY into C57BL6 mice cause

202 Twenty-four hours after the intratracheal instillation of PM(2.5), wild-type mice sh

203 study, we observed that pneumonia induced by intratracheal instillation of Pseudomonas aeruginosa (PA

204 Intratracheal instillation of recombinant mouse IL-36alp

205 either intraperitoneal delivery of AAL-R nor intratracheal instillation of the non-phosphorylatable s

206 In the present study, intratracheal instillation of this PKCdelta inhibitor re

207 Treatment of mice with intratracheal instillation of TSG6 prevented LPS-induced

208 utrophil-mediated pulmonary injury evoked by intratracheal instillation or i.p. administration of liv

209 models of infection have primarily relied on intratracheal instillation or small particle aerosolizat

210 After intratracheal instillation, labeled apoptotic cells were

211 We found that upon intratracheal instillation, particulates such as aluminu

212 recombinant replicated in the monkeys after intratracheal instillation, the first demonstration of r

213 ore efficiently than control PA01 2 hours of intratracheal instillation.

214 impaired compared with BLT1(+/+) BMDCs after intratracheal instillation.

215 omeric IP-10 were retained in the lung after intratracheal instillation.

216 D was readily detected in the lung 5 h after intratracheal instillation.

217 CD8+ T cells into the airways of mice after intratracheal instillation.

218 delivered therapeutically to rats after LPS intratracheal instillation.

219 inoculation of monkeys via the subcutaneous, intratracheal, intravenous, or oral-nasal-conjunctival r

220 ion of the virus by intranasal inhalation or intratracheal intubation.

221 Recently, it was demonstrated that intratracheal (IT) inoculation of nonpregnant guinea pig

222 (3) BaSO(4) NP aerosols, and Study 2: single intratracheal (IT) instillation of increasing doses of B

223 ination, and reduced survival in response to intratracheal K. pneumoniae administration.

224 activation of NF-kappaB and MAPKs following intratracheal K. pneumoniae infection.

225 ophils to the lung triggered by inhaled LPS, intratracheal KC chemokine, and intratracheal Klebsiella

226 response to neutrophil migration induced by intratracheal keratinocyte chemokine.

227 inhaled LPS, intratracheal KC chemokine, and intratracheal Klebsiella pneumoniae and impairs pulmonar

228 ination and serum inflammatory markers after intratracheal KP infection compared with wild type.Concl

229 Intratracheal lidocaine, iso-PPADS, and TRPV4 genetic de

230 (5 ng/g b.wt.) in the presence or absence of intratracheal lipopolysaccharide (51 microg).

231 Acute lung inflammation was induced by intratracheal lipopolysaccharide inoculation.

232 Results: Intratracheal lipopolysaccharide instillation led to an

233 In the intratracheal lipopolysaccharide model, 1,500 IU of intr

234 We administered intratracheal lipopolysaccharide to wild-type mice and o

235 ne models of cecal ligation and puncture and intratracheal lipopolysaccharide were undertaken in norm

236 In control lambs, intratracheal lipopolysaccharides caused septic shock an

237 eutrophil recruitment in the lungs following intratracheal LPS administration in dfy(-/-) and dfy(+/+

238 esolution, we exposed wild type (WT) mice to intratracheal LPS and assessed the response at intervals

239 As a model, we administered intratracheal LPS and observed peak lung injury at 3 d,

240 In mice challenged with intratracheal LPS and then exposed to febrile range hype

241 Male C57BL/6J mice received 300 microg/kg intratracheal LPS and were exposed to acrolein (5 parts

242 transferred into lungs of naive mice before intratracheal LPS challenge diminished proinflammatory c

243 Intratracheal LPS elicited an exaggerated systemic infla

244 llular apoptosis in C57BL/6J mice exposed to intratracheal LPS for 24 h.

245 nase-M, Toll-interacting protein, and A20 by intratracheal LPS in vivo and in macrophages in vitro wa

246 Intratracheal LPS induced release of pro-interleukin-1al

247 In mice treated with intratracheal LPS or keratinocyte chemokine, neutrophil

248 g inflammation and platelet activation after intratracheal LPS or Pseudomonas aeruginosa challenge.

249 ux, and reduced lung injury in CF mice after intratracheal LPS or Pseudomonas aeruginosa challenge.

250 he combination of mechanical ventilation and intratracheal LPS produces significantly more injury to

251 s had pulmonary inflammatory responses after intratracheal LPS that were similar to those of wt mice.

252 ra2b to ALI, utilizing a two-hit model where intratracheal LPS treatment is followed by injurious mec

253 When iNOS-/- mice were exposed to intratracheal LPS, early lung injury was attenuated; how

254 In response to intratracheal LPS, neutrophils migrate into the lung, an

255 ADD45a(-/-) mice are modestly susceptible to intratracheal LPS-induced lung injury and profoundly sus

256 n and animals allocated at random to receive intratracheal maternal administration of nitrogen (n=8)

257 Results from a group of mice receiving intratracheal normal saline without surgical interventio

258 Upon a combination of intratracheal, ocular, oral, and intranasal inoculation

259 We found that C57BL/6 mice given intratracheal or s.c. immunization of conidia prior to c

260 flagellin induced strong protection against intratracheal P. aeruginosa-induced lethality, which was

261 -induced PAH rats than oral, intravenous, or intratracheal plain sildenafil did, when administered at

262 ild-type mice to develop edema with low-dose intratracheal PLY, correlating with reduced pulmonary EN

263 g protein L-plastin (LPL) succumb rapidly to intratracheal pneumococcal infection.

264 om the skin was examined in murine models of intratracheal pneumonia and subcutaneous infection.

265 Intratracheal post-treatment with LPA (5 microm) reduced

266 hat TRPV4 protects the lung from injury upon intratracheal Pseudomonas aeruginosa in mice.

267 We compared intratracheal Pseudomonas infection in wild type and cav

268 ed sepsis followed by secondary challenge by intratracheal Pseudomonasaeruginosa.

269 with MK571 decreased k (E,lung) by 20% after intratracheal radiotracer administration.

270 Intratracheal recombinant human SP-D prevented shock cau

271 to the systemic circulation was prevented by intratracheal recombinant human SP-D.

272 Administration of intratracheal recombinant MCP-1 (rMCP-1) to MCP-1(-/-) m

273 Finally, the intratracheal reconstitution of IL-23 in TLR9(-/-) mice

274 Intratracheal replenishment of adenosine triphosphate in

275 from the Ad recombinants (intramuscular and intratracheal, respectively), too few DNA priming immuni

276 Intriguingly, administration of intratracheal rG-CSF to MCP-1(-/-) mice after K. pneumon

277 Intratracheal rhSOD and/or iNO rapidly increase oxygenat

278 (ALI), we delivered LPS or bleomycin by the intratracheal route to MMP-8(-/-) mice versus wild-type

279 to bleomycin, we delivered bleomycin by the intratracheal route to wild-type (WT) versus Mmp-8(-/-)

280 ependent part of the trachea, leading to an "intratracheal route" of colonization of the lungs.

281 s of African green monkeys by the intranasal/intratracheal route.

282 with influenza virus A/Anhui/1/2013 via the intratracheal route.

283 us A/Netherlands/602/09 by the intranasal or intratracheal route.

284 -infect donor ferrets via the intranasal and intratracheal routes to cause an upper and lower respira

285 n of rhesus macaques via both intranasal and intratracheal routes with MuV-IA led to the typical clin

286 lenged with SARS-CoV-2 by the intranasal and intratracheal routes(9,10).

287 mental infection in pigs, via intranasal and intratracheal routes, was performed using one representa

288 e and female mice were treated with 0.2 g/kg intratracheal silica, and lung injury was assessed 1, 3,

289 ted from mice, 48 hours after treatment with intratracheal small interfering RNA targeting Fas, contr

290 Administration of intratracheal SP-A to Sp-a(-/-) mice induced the translo

291 ferred about 50% protection against a lethal intratracheal spore challenge by the virulent B. anthrac

292 ene delivery system that offers an effective intratracheal strategy for administering lung cancer gen

293 , but differences were more pronounced after intratracheal than after intravenous administration.

294 ted with anti-MHC I antibody in vitro before intratracheal transfer failed to modulate AHR or inflamm

295 Furthermore, naive mice receiving intratracheal transfer of airway CD8 TRM cells lacking t

296 ith anti-Thy1.2 mAb and replaced by means of intratracheal transfer of ex vivo expanded Thy1.1 ILC2s.

297 mined by determining the response of mice to intratracheal transfer of OVA-pulsed or OVA-alpha-galact

298 Intratracheal transfers of enriched CD68(+) cells isolat

299 in familial interstitial pneumonia and (ii) intratracheal treatment with the protein misfolding agen

300 With a complementary model, intratracheal tunicamycin treatment failed to induce lun