ライフサイエンスコーパス: introduction of

1 Further, the introduction of ~0.2 wt % of atomically dispersed Rh to

2 The introduction of 4 direct oral anticoagulants beginning i

3 Control was achieved through the introduction of a base-pair mismatch in the duplex of th

4 The introduction of a bioisostere leads to structural change

5 tional benzocyclobutene-based materials, the introduction of a butoxide substituent at the 7-position

6 The introduction of a catalyst, which introduces a second ca

7 The introduction of a CDP auxiliary was anticipated to promo

8 Possibly, the introduction of a classification system for duodenal div

9 Fe(14) Nd(2) B magnet, concomitant with the introduction of a concentration gradient (decrease in te

10 In contrast, the introduction of a constitutively active oncogenic KRas m

11 We found that the introduction of a cysteine pair in the receptor-binding

12 and finally eliminating formic acid with the introduction of a Delta14-15 double bond in the sterol c

13 ission limit value that typically forced the introduction of a diesel particulate filter.

14 onal changes were partially rescued with the introduction of a genetic suppressor of tau pathology.

15 In mice, introduction of a germline mutation at Bahcc1 to disrupt

16 In contrast, introduction of a mimic nanodrug decreased PTEN expressi

17 The introduction of a moderate thermal-contact stress upon t

18 Introduction of a mutation into mice that is analogous t

19 to audit clinical practices before and after introduction of a national guideline in Wales on RDS man

20 soft pneumatic actuators (SPAs) has been the introduction of a new class of actuators called fabric s

21 transformation was accomplished through the introduction of a new strategy that involves the use of

22 emerging respiratory infection caused by the introduction of a novel coronavirus into humans late in

23 Although the introduction of a preprocessing step reduces the PoC cap

24 ystems has taken another major leap with the introduction of a ring-shaped gantry equipped with multi

25 Introduction of a sample containing an analyte and the d

26 Mechanistically, the introduction of a second IQ domain to the Ca(V)1.3 carbo

27 tbreak among PWID over 5 years following the introduction of a single infection into the network.

28 Furthermore, we find that the introduction of a small concentration of magnetic impuri

29 Furthermore, the introduction of a switchable magnetic trap enables repet

30 MS/MS was for the first time overcome by the introduction of a ternary pump system.

31 We show how the GRN is resilient to the introduction of a transcription factor, pmar1, the inclu

32 -response relationships are nonhyperbolic by introduction of a transducer slope that relates receptor

33 The introduction of a typhoid conjugate vaccine would protec

34 et-targeting substituent was followed by the introduction of a variety of P-loop-targeting functional

35 alkynylation of the terminal alkyne, whereas introduction of a weakly basic triflate counteranion res

36 t stereochemical information, and subsequent introduction of absolute stereochemistry through desymme

37 of existing personal devices rather than the introduction of additional instrumentation, smartphone-b

38 The introduction of agriculture triggered a major population

39 th kinetically controlled diastereoselective introduction of all three elements of atropisomerism.

40 rsor to N(2) and O(2) formation, without the introduction of ammonia (NH(3)), during the reaction of

41 off-target editing can be ameliorated by the introduction of an additional mutation in the TadA-8e do

42 We report the successful introduction of an antimicrobial stewardship approach in

43 However, the introduction of an azetidine can be synthetically challe

44 Introduction of an effective pretravel typhoid vaccine f

45 een different substances is addressed by the introduction of an electrode pretreatment and the integr

46 H sensitivity of the dyes is achieved by the introduction of an electronically decoupled, photoinduce

47 three related transcription factors allowed introduction of an important harvesting trait in modern

48 With the introduction of an in vivo assessment platform comprised

49 mproving Global Outcomes guidelines with the introduction of an integrative risk-based approach.

50 Introduction of an intermittent 5/7-day schedule improve

51 ith non-analog conditions resulting from the introduction of an invader to an ecosystem.

52 The introduction of an optimal amount of hydrogen bonds sign

53 The introduction of an X-ray synchrotron beamline designed t

54 Despite the introduction of anthracycline-based chemotherapy protoco

55 Introduction of anti-angiogenic drugs targeting vascular

56 On the other hand, introduction of anti-miR-181c restored ATM and phosphory

57 The Introduction of antibiotics into the clinical use in the

58 vileged organ, the placenta can tolerate the introduction of antigens without inducing a strong infla

59 res and quantitative regional volume without introduction of any contrast agents.

60 ct for modifying social interactions via the introduction of artificial agents into hybrid systems of

61 hile photophysical study highlights that the introduction of aryl substituents at position 23 of the

62 Phylogenetic analyses revealed the cryptic introduction of at least seven different SARS-CoV-2 line

63 nal theory (DFT) simulations reveal that the introduction of atomic-level interfaces can lower the ox

64 ameworks are implemented before the complete introduction of AVs into the market.

65 r global phylogeny suggest that the original introduction of B. pseudomallei to Myanmar was not a rec

66 nurses' preferences could jeopardize future introduction of bedside handover in Swedish health care,

67 tomegalovirus reactivation subsequent to the introduction of belatacept.

68 G frequencies similar to those caused by the introduction of biocontrol isolates were detected in Son

69 ases in hip fracture rates that followed the introduction of bisphosphonates have now levelled off, w

70 is approach, has recently benefited from the introduction of blue light assisted photodynamic diagnos

71 Introduction of BMP10-specific residues into BMP9 yields

72 Meanwhile, the introduction of bovine serum albumin (BSA) and antibody

73 bunits during desensitization processes, the introduction of bulky amino acids at the A-C interface p

74 e corresponding [2]rotaxanes are obtained by introduction of bulky stoppering ("capping") units at th

75 a one-pot protocol for the oxodealkenylative introduction of carbonyl functionalities into terpenes a

76 gnosis of myocarditis has changed due to the introduction of cardiac magnetic resonance imaging.

77 terization of 42 cell line pairs showed that introduction of Cas9 can lead to the emergence and expan

78 hanol process, represents an opportunity for introduction of cellulose conversion technology.

79 The introduction of chemical strategies to parse and enrich

80 The introduction of chemical tuning within our ternary syste

81 ial for LLPS) dominates the phase landscape, introduction of clients (species recruited via scaffold-

82 h was reported here by the authors, with the introduction of 'Cognitive Demodulation'.

83 mas is expected to further increase with the introduction of colorectal screening programs throughout

84 ge, longer breastfeeding duration, and later introduction of complementary feeding were associated wi

85 This method enables the late-stage introduction of complex alkoxy groups into bioactive mol

86 These findings provide some support for the introduction of conjugate vaccines in Nepal, including o

87 of this technique were conducted before the introduction of consensus guidelines defining a "positiv

88 librium in a sequenced individual due to the introduction of contaminant DNA.

89 type ATPase, were investigated following the introduction of copper impulse to reach a copper concent

90 The introduction of copper tunes the d-band electron configu

91 d control measures are needed to prevent the introduction of Covid-19.

92 With the introduction of CRISPR cleavage activity into the E-DNA

93 Introduction of CTL therapy was associated with improved

94 The introduction of Cu not only shifts the partial density o

95 The introduction of custom bandpass optical filters enables

96 enzymatic degradation mechanism involves the introduction of defects, which promotes further degradat

97 overcome through self-sorting favored by the introduction of designed shape-complementary moieties.

98 hinning coupled with expansion or during the introduction of different cell types into an epithelium.

99 uidics disrupted analytical biology with the introduction of digital polymerase chain reaction and si

100 and mortality, all but disappeared following introduction of diphtheria vaccine.

101 ophic structure can become unstable with the introduction of dispersal in space, and we discuss the f

102 e identify a Peruvian origin for the initial introduction of domesticated guinea pigs (Cavia porcellu

103 We modeled the introduction of DTG in 2020 under 2 scenarios: DTG as fi

104 ustrates that accounting for the intentional introduction of economic plants is key to unravelling dr

105 nts and refinements needed to accelerate the introduction of effective therapeutic approaches.

106 on have been increasing, especially with the introduction of electronic medical records.

107 With the introduction of emicizumab, the bispecific ACE910 antibo

108 The introduction of endotyping has led to a differentiation

109 far from equilibrium through the continuous introduction of energy or matter.

110 lation, where meta-analyses have shown early introduction of enteral feeds to be beneficial to hospit

111 itive end expiratory pressures and timing of introduction of enteral feeds.

112 The early introduction of EVR after KT did not increase the risk o

113 Human-assisted introductions of exotic species are a leading cause of a

114 The introduction of farming had far-reaching impacts on heal

115 sensus meetings during a 5-year period after introduction of FFDM, including recall rates, cancer det

116 f consensus review remained stable after the introduction of FFDM.

117 sion to the hospital was unchanged after the introduction of FilmArray GI panel, but length of hospit

118 inment strain growth, which is restored upon introduction of fluoride-based vectors.

119 Early introduction of food allergens into children's diet is c

120 e looked at consensus outcomes following the introduction of full-field digital mammography (FFDM).

121 abnormalities remains a valuable tool after introduction of full-field digital mammography as it red

122 These processes enable the introduction of functionalized alkyl chains at Cbeta, gr

123 o that the effects of 11S RP binding, or the introduction of gate or allosteric pathway mutations at

124 With the introduction of generic, low-cost sofosbuvir and daclata

125 Additionally, the introduction of genome-scale metabolic models have also

126 The introduction of GIP testing as an assessment technique f

127 wider processes of Islamization, such as the introduction of glazed ceramics that are compositionally

128 ted in an orthogonal cell line system by the introduction of H3.3-G34W.

129 s in HeLa cells can be circumvented upon the introduction of H5N1 virus HA and NP.

130 While the introduction of herbicide tolerant crops provided grower

131 lkweed (Asclepias sp.) host-plants after the introduction of herbicide-tolerant crops.

132 After the introduction of horizontal translation factors to longit

133 The introduction of HPV vaccination does not seem to have ha

134 ated) boys, with no relationship to the 2009 introduction of HPV vaccine to Denmark's vaccination pro

135 Introduction of human wild-type CNOT1 was able to rescue

136 The introduction of immunomodulatory agents, proteasome inhi

137 d with CME was observed before and after the introduction of immunotherapy (P = .030 and P = .038).

138 Such methods were limited by the introduction of in vitro noise through polymerase slippa

139 Transposon-based introduction of InDels via the method TRIAD (transpositi

140 The introduction of induced pluripotent stem cell methodolog

141 The risk of introduction of invasive non-native species to the APR i

142 potheses related to the source and timing of introduction of invasive species.

143 verty reduction, improved food security, and introduction of land and health reforms have contributed

144 ells (S/G2-phase) and its efficiency for the introduction of large DNA sequences in zygotes is low.

145 ble early-stage colonizers to survive during introduction of later colonizers.

146 The introduction of Li(x) LM(y) not only prevents dendrite f

147 important unique feature of RETrace was the introduction of linear amplification of microsatellites

148 ore than half a century has passed since the introduction of lithium into widespread use at the birth

149 Four years following an experimental introduction of lizards to replicate experimental islets

150 Moreover, introduction of lysine, glutamine or proline at residue

151 As expected, the introduction of m(1)A to model mRNAs was found to reduce

152 Finally, the introduction of Mcl-1 TMD somatic mutations detected in

153 Introduction of microfluidic mixing technique opens a ne

154 sion wave cumulative intensity following the introduction of milrinone.

155 Introduction of minimal invasive, laparoscopic donor nep

156 The introduction of minimally invasive esophagectomy (MIE) h

157 Following introduction of minimum unit pricing in Scotland, alcoho

158 Furthermore, introduction of miR-181c significantly inhibited phospho

159 arely perturbing forward reaction rates: the introduction of mismatches within the initial duplex.

160 e presence of Cu, which was abrogated by the introduction of mntA::Tn.

161 It has been 10 years since the introduction of modern transposon-insertion sequencing (

162 tments to the histological diagnosis and the introduction of molecular classification are providing r

163 In addition, the introduction of molecular-based diagnosis, allowed to be

164 In the past decade, the introduction of molecularly targeted agents and immune-c

165 individualized weight loss results with the introduction of more fiber, whole grain, intrinsic sugar

166 feedstock alicyclic amines, the simultaneous introduction of more than one substituent to unprotected

167 t and a weakened gating effect caused by the introduction of MoS(2) layers.

168 Here, we present the successful introduction of multiple bis-deoxygalactosyl-carborane b

169 pecific methods that require multiple steps, introduction of mutations, or use of enzymes.

170 We find introduction of NaSbTe(2), but not NaBiTe(2), into SnTe

171 While the introduction of network disorder decelerates IL exudatio

172 y modified proteins from side streams or the introduction of new protein sources that may lead to inc

173 e often cited as theoretical vectors for the introduction of new species into Antarctica and the sub-

174 nd, immediately after lockdown and after the introduction of new treatments to reduce patient risk.

175 Recent introductions of new technologies including active solve

176 Upon introduction of Nile blue (NiB) as an acceptor into the

177 Introduction of NMDA receptor antagonists was correlated

178 lake in Northern Spain where, following the introductions of non-native species, the last resident n

179 Zoonotic introduction of novel coronaviruses may encounter preexi

180 ogical advances in computing have led to the introduction of novel physiological biosignals that can

181 1N1:H5N1 viruses, we found that the combined introduction of nucleoprotein (NP) and hemagglutinin (HA

182 Despite the introduction of numerous biologic agents for the treatme

183 Introduction of oil and gas extraction wastewaters (OGWs

184 easurement times (~tens of days), continuous introduction of organic fuels (~tends of milliliters), a

185 The introduction of oxygen into the Earth's atmosphere broug

186 tion on hollow TiO(2) nanowires leads to the introduction of parts per millions of boron, sodium, and

187 The introduction of PCV10 was associated with a decrease in

188 Introduction of PCV13 or PPV23 in the adult calendar of

189 randomised trial conducted before nationwide introduction of PCV7 (2009) and PCV13 (2011).

190 stonic disorders, providing guidance for the introduction of personalised care strategies and fosteri

191 influenced the optical properties, where the introduction of phenyl groups caused a progressive red-s

192 panded to nuclear hormone receptors with the introduction of "photohormones" for the retinoic acid re

193 uents for antitubercular activity, while the introduction of polar substituents on the quinazolinone

194 Furthermore, the introduction of polarization enriches this technique by

195 ,650,000 per surgeon-year) realized with the introduction of policies mandating that a second patient

196 expect significant financial loses with the introduction of policies restricting OR scheduling.

197 The introduction of poly(dimethylsiloxane) (PDMS) and soft l

198 The introduction of polysomnography into psychiatric researc

199 Introduction of pore partition agents into hexagonal cha

200 The introduction of precision medicine to manage this chroni

201 netic diseases and cancers are caused by the introduction of premature termination codons (PTCs).

202 g the new methodologies that have led to the introduction of programmable and automatic as well as la

203 s in ambient [CO(2)] and temperature and the introduction of progressively shorter straw varieties.

204 se of concerns of late toxic effects and the introduction of radiation-free regimens.

205 Before the introduction of rapid ART, 163 (9.5%, 95% CI 8.2-11.0) i

206 We inferred three independent introductions of rats, including to Suouroy, the islands

207 atrices, as well as the direct interface and introduction of said analytes into the mass spectrometer

208 Dane County had the 12(th) known introduction of SARS-CoV-2 in the United States, but thi

209 pidemiological analysis confirmed that early introductions of SARS-CoV-2 originated from mainland Eur

210 In the second step, introduction of Sb-doping leads to additional phonon sca

211 II, using thenoyltrifluoroacetone (TTFA) or introduction of SDHC R72C mutant, independently sensitiz

212 Finally, the recent introduction of semiconductor nanomaterials into hybrid

213 arkers were significantly improved after the introduction of Sepsis Alert, including number of blood

214 With the introduction of several effective treatment options, it

215 To explore the potential impact of the introduction of severe acute respiratory syndrome corona

216 e aimed to identify the source and number of introductions of severe acute respiratory syndrome coron

217 s in other related discotic molecules by the introduction of similar bulky functional groups at their

218 With the introduction of simple holographic imaging methods in cl

219 Furthermore, the introduction of single metal atoms anchored onto support

220 nts, meaning that simultaneous correction or introduction of single nucleotide variants is required f

221 The introduction of single-cell platforms inspired the devel

222 Base editing - the introduction of single-nucleotide variants (SNVs) into D

223 The introduction of site-specific mutations predicted to alt

224 9.1% to 54.2%, p < 0.001) at 12 months after introduction of SMASH.

225 its shaping by maternal factors and upon the introduction of solid food (the weaning reaction).

226 Early introduction of solid foods synchronizes with the "weani

227 The introduction of sophisticated immunomodulatory therapies

228 Human introductions of species beyond their natural ranges and

229 Introductions of species by humans are causing the homog

230 Capsid stability was restored by introduction of specific changes to the outer capsid, in

231 ish young children provide evidence that the introduction of SSBs during the first year of life can p

232 However, the introduction of streptavidin as a linker to the capture

233 rmances with promising possibilities for the introduction of such automatic methods in the clinical p

234 019 (COVID-19) is social distancing, but the introduction of such measures is hampered by the fact th

235 iency in vitro increased significantly after introduction of SV40 enhancer for plasmid pCMV-ABCA4-SV4

236 The introduction of systemic therapies, including immune-bas

237 very vectors should facilitate the efficient introduction of targeted point mutations into multiple t

238 ediated base editing to enable the efficient introduction of targeted point mutations into the genome

239 Following programmatic introduction of the 13-valent pneumococcal conjugate vac

240 r time and then decreased with and after the introduction of the 2009 pandemic H1N1 IAV of Eurasian s

241 aura borylation-Suzuki coupling sequence for introduction of the AB biaryl axis of chirality (>20:1 d

242 The introduction of the acp3U-47 modification in E. coli tRN

243 ons in the I-II loop (GGG-alpha(1C)), or (3) introduction of the alternatively spliced 25-amino acid

244 late salt serves well as a surrogate for the introduction of the cationic 2-(1,2'-bipyridin)-1-iumyl

245 The introduction of the delta heteroatom in each residue all

246 ona fide LCB desaturase and required for the introduction of the Delta14Z double bond.

247 Introduction of the direct oral anticoagulants (DOACs) h

248 ed and Horner-Wadsworth-Emmons reactions for introduction of the dithiafulvene units.

249 With the introduction of the dynamically harmonized FT ICR cell,

250 chloroquine (CQ) transport activity, but the introduction of the eight mutations present in the 'Dd2'

251 However, we find that the introduction of the encapsulating "arms" results in the

252 Its definition is being rethought with the introduction of the eplets in organ allocation.

253 In contrast, introduction of the exon 9* splice variant in the alpha(

254 timal antibiotics were started earlier after introduction of the FilmArray GI panel (hospital day 1 v

255 hip dates to the early 20th century with the introduction of the focal infection theory that posited

256 inal D614 form was well established prior to introduction of the G614 variant.

257 was compared with a 50% reduction of CNI and introduction of the mammalian target of rapamycin inhibi

258 The introduction of the ME panel reduced the duration of acy

259 intensity of the porphyrin in the MOFs upon introduction of the molecular motor pillars confirms eff

260 Comparing care before and after introduction of the national guideline, areas of signifi

261 urface engineering has opened the way to the introduction of the next generation of Quantum PIs.

262 The recent introduction of the OrbiSIMS has significantly improved

263 face property of the droplet system with the introduction of the receding TCL, which increased the in

264 Specifically, only the introduction of the RL13 mutant partially phenocopied th

265 of pediatric malaria admissions ahead of the introduction of the RTS,S/AS01 vaccine.

266 ss spectrometry experiments require physical introduction of the sample in the ionization source.

267 ut requiring sample pretreatment (before the introduction of the sample in the microfluidic chip) and

268 Introduction of the second chiral center and subsequent

269 Here, using the human-mediated introduction of the silvereye (Zosterops lateralis) to F

270 sophoroside in the plasma following jejunal introduction of the sophoroside; we found derivatives of

271 Stable introduction of the Spike-activating protease TMPRSS2 fu

272 We previously showed that introduction of the temperature-sensitive (ts) residue s

273 arge-scale outbreak is likely after a single introduction of the virus into the camp, with 61%-92% of

274 Other, later introductions of the virus from China to both Italy and

275 y interventions successfully prevented early introductions of the virus from taking hold in Germany a

276 n the Boston-area epidemic revealed numerous introductions of the virus, a small number of which led

277 The introduction of these groups around the aromatic unit is

278 Introduction of these residues into Drosophila TRPA1 con

279 sialyl-di-Lewis(a)-targeting i129G1 mAb via introduction of these selected residues into 129hIgG1, c

280 The introduction of these two different groups led to the se

281 IR, EDX and SEM, which demonstrated that the introduction of thiol groups improved the adsorption cap

282 The introduction of third-generation DNA sequencing technolo

283 Introduction of this D/E-P motif into malate importer, A

284 The late-stage introduction of this functional group is challenged by t

285 Introduction of this minor allele SNP by genome editing

286 ryo-EM structure of human Nav1.7 showed that introduction of this negatively charged site seems to al

287 Our findings support the introduction of TMS measures in clinical and research se

288 The outbreak ended soon after the introduction of total isolation of patients and barrier

289 ith cell therapies but currently rely on the introduction of transgenes.

290 The introduction of transition metals makes it possible for

291 After the introduction of translation factors, the effective radiu

292 However, following introduction of treatment options to reduce patient risk

293 Introduction of tungsten allows reversible lithium-ion i

294 Moreover, the introduction of two catalytic glutamate residues conserv

295 Introduction of two different ChAc disease-linked missen

296 We found that the introduction of two insulin substitutions, A14E and B25H

297 of potential disease elimination through the introduction of typhoid conjugate vaccine (TCV), we agai

298 The introduction of well-population screening using new and

299 ted reduced Cx43 expression, rescued upon re-introduction of wild-type Dsg1, but not Dsg1 constructs

300 Here, we report stable introduction of Wolbachia into the brown planthopper, Ni