ライフサイエンスコーパス: invagination

1 domain mouth suggesting a flattening of the invagination.

2 elongating or shaping the endocytic membrane invagination.

3 from cytokinesis to epithelial extension or invagination.

4 ntal mesenchymal condensation and epithelial invagination.

5 ged in a deep narrow pit created by membrane invagination.

6 lindrical to flat shape with longer membrane invagination.

7 a to fully surface, losing the deep membrane invagination.

8 strates membrane and peptidoglycan cell wall invagination.

9 but is abolished in the absence of endoderm invagination.

10 negatively curved annulus at the rim of the invagination.

11 owing actin polymerization to drive membrane invagination.

12 septal peptidoglycan synthesis and membrane invagination.

13 ation as monitored by ScxGFP, and interdigit invagination.

14 is conserved throughout the entire course of invagination.

15 ugh cell division, cell differentiation, and invagination.

16 ession and increased variability of mesoderm invagination.

17 nd actin to control the extent of epithelial invagination.

18 ays a critical role in regulating epithelial invagination.

19 ker and hair follicle epithelium rather than invagination.

20 rotrusion formation by Arp2/3 protein blocks invagination.

21 ontributes to the driving force for membrane invagination.

22 elia during Drosophila melanogaster mesoderm invagination.

23 tagonist) mouse mutants exhibited dysmorphic invagination.

24 ing eye morphogenesis by asymmetric, ventral invagination.

25 tivates the Arp2/3 complex to drive membrane invagination.

26 t may block the completion of outer membrane invagination.

27 tissue-level myosin cable contributes to SG invagination.

28 gh such manipulations affect the geometry of invagination.

29 nation for the formation of nuclear membrane invaginations.

30 contractile ectoderm induced ectopic tissue invaginations.

31 otypic deviations of tip swelling and apical invaginations.

32 toplasmic invaginations, are not just simple invaginations.

33 ghly concentrated protons within the cristae invaginations.

34 Ps keep cilia submerged within deep membrane invaginations.

35 morphogenesis, including extensive cell wall invaginations.

36 he flat membrane is efficiently nucleated at invaginations.

37 t-bound CTB separately from BCR into tubular invaginations.

38 imaging and electron microscopy of endocytic invaginations.

39 ; specifically, the formation of cytoplasmic invaginations.

40 sed electron density, abnormal linearity and invaginations.

41 scaffold around furrow-like plasma membrane invaginations.

42 pidermal cells, or enclosed within epidermal invaginations.

43 rmal histone methylation, and nuclear lamina invaginations.

44 genetic marks segregated by their associated invaginations.

45 sely associated with SAP102 in photoreceptor invaginations.

46 he formation of cristae-like plasma membrane invaginations.

47 ay of three different types of force driving invagination: 1), forces perpendicular to the membrane,

48 oordinated apical constrictions that mediate invagination [5, 6].

49 s feature numerous and deep nuclear envelope invaginations, a hallmark of cellular stress.

50 g yeast produce enough force to elongate the invagination against the turgor pressure.

51 s cell rearrangement in this tissue to drive invagination all the way to bud formation.

52 sion were present at the areas of epithelial invagination and adjacent to osteonecrotic bone.

53 epithelia and leads to multiple attempts at invagination and an expanded enamel organ.

54 of polymerized actin in the vicinity of the invagination and because of entanglement of the meshwork

55 ate early morphogenetic events including the invagination and branching of three different and interc

56 conical cellular shape that enables hair bud invagination and downgrowth.

57 brane assembly at the cell periphery; (2) PM invagination and formation of a perinuclear pre-DMS; (3)

58 is regulated spatiotemporally during tissue invagination and how this cellular process contributes t

59 This coordination links PG synthesis with OM invagination and imparts a unique mode of bifunctional P

60 al epithelial layer that inhibits epithelial invagination and incisor development.

61 ously untested minimal conditions for tissue invagination and is devoid of specificity needed to accu

62 protein syndapin III is crucial for caveolar invagination and KO rendered the cells sensitive to memb

63 that connects cell wall elongation to septal invagination and may be the reason ZipA is essential in

64 polymerization-rate values provide effective invagination and obtain correct predictions for the effe

65 thelial signaling centers control epithelial invagination and organ development, but how these center

66 sition of outward membrane tension minimized invagination and PtdSer endocytosis.

67 e membrane were also accompanied by membrane invagination and rapid membrane destabilization.

68 transmitted to the plasma membrane to drive invagination and scission.

69 rated forces to the plasma membrane to drive invagination and scission.

70 these rearrangements, particularly membrane invagination and spherule formation, remain essentially

71 A loss of KDM4B results in defective invagination and striking morphological changes in the o

72 is to help generate the force that leads to invagination and then fission of clathrin-coated pits.

73 to the plasma membrane, leading to membrane invagination and vesicle budding.

74 ed with ESCRT-III-filament-mediated membrane invagination and vesicle formation.

75 by classical endocytosis involving membrane invagination and vesicle reformation; (b) kiss-and-run,

76 filament assembly drives endocytic membrane invagination and vesicle scission.

77 ed ExM to characterize the shapes of nuclear invaginations and channels, and to visualize cytoskeleta

78 ella quickly colonizes epithelial crypt-like invaginations and demonstrates the essential role of the

79 mposed by the N-BAR proteins results in deep invaginations and endocytic vesicular bud-like deformati

80 al tumor corresponding to surface epithelial invaginations and papillomatosis frequently found in pos

81 hila CAP mutants exhibit aberrant junctional invaginations and perturbation of the cytoskeletal organ

82 aracterized by sparse transverse tubule (TT) invaginations and slow intracellular Ca2+ propagation bu

83 nuclease digestion by virus-induced membrane invaginations and that spherules play an important role

84 x) mice that loss of Pitx2 delays epithelial invagination, and decreases progenitor cell proliferatio

85 ryo: premature cell division during mesoderm invagination, and native ectodermal cell divisions with

86 ed in which actin filaments bind Vps1 during invagination, and this interaction is important to trans

87 The mechanisms driving stratification and invagination are poorly understood.

88 Tissue folding and invagination are thought to be facilitated by apical con

89 acterized by blebs, lobules, micronuclei, or invaginations are hallmarks of many cancers and human pa

90 Invaginations are stabilized by phosphatidylinositol 3-p

91 We found that both mesoderm and endoderm invaginations are synchronous with the onset of GBE.

92 Human nuclear membrane (hNM) invaginations are thought to be crucial in fusion, fissi

93 eorientation, junction formation, and active invagination, are directed by coordinated release of spe

94 , although probably derived from cytoplasmic invaginations, are not just simple invaginations.

95 Using Drosophila salivary gland (SG) invagination as a model, we show that regulation of fold

96 is constant volume is sufficient to generate invagination as a passive response to apical constrictio

97 ry and sufficient for stratification but not invagination as such.

98 multiprotein structures that generate linear invaginations at the plasma membrane of yeast cells.

99 not determine the membrane morphology of the invagination but rather modulates the progression of end

100 Microtubules were required for mesoderm invagination but were not necessary for initiating apica

101 d by a local supply of membrane from tubular invaginations, but the interplay between the expanding b

102 lies seen in paediatric patients are basilar invagination, C1-C2 instability, atlantoaxial rotatory s

103 at is the primary component of cell membrane invaginations called caveolae.

104 consists of the inner boundary membrane and invaginations called cristae, which differ in protein co

105 host mitochondria to form numerous membrane invaginations, called spherules, that are approximately

106 cell level, a complex network of sarcolemmal invaginations, called the transverse-axial tubular syste

107 scaffolding protein found in plasma membrane invaginations (caveolae).

108 We detected nuclear invagination channels at late prophase and telophase, po

109 ic factors and show that constriction of the invaginations correlates with translocation of membrane-

110 The internal mitochondrial membranes invagination (cristae) complexity was calculated by the

111 r exhibit cell polarity defects that lead to invagination defects at gastrulation, demonstrating a pr

112 Here, we show that placode invagination depends on horizontal contraction of superf

113 microscopy reveals a significant increase in invagination depth, further supporting a role for the Vp

114 a protein that localizes to plasma membrane invaginations designated as eisosomes.

115 s epithelial folding, while neighboring cell invagination determines the final depth of an epithelial

116 e discuss a plausible mechanism for membrane invagination driven by ESCRT-III.

117 daughter cell separation and outer membrane invagination during division.

118 eation in yeast and is required for membrane invagination during endocytosis.

119 o resulted in the formation of deep membrane invaginations during meiosis, suggesting an effect on co

120 esicular endoplasmic reticulum (ER) membrane invaginations, each induced by many copies of viral repl

121 to endocytic factors and facilitates vesicle invagination, elevating neuritogenic Rac1 activity and e

122 Caveolae are plasma membrane invaginations enriched with high cholesterol and sphingo

123 own to induce narrow tubular plasma membrane invaginations enriched with sphingosine kinase 1 (SphK1)

124 es at the midcell is not sufficient to cause invagination, even with the implementation of a make-bef

125 tractile cell-shaping mechanism, as mesoderm invagination fails in Rab35 compromised embryos and Rab3

126 The invagination flattens to create the proximal surface of

127 ells have an indented, elongate nucleus with invaginations, folded plasma membrane, and multiple apic

128 the division machinery and directs envelope invagination for bacterial cytokinesis.

129 ay be necessary for the formation of similar invaginations for the synthesis of dsRNA precursors of h

130 nding toward virions sequestered deep inside invaginations formed on the DC membrane.

131 n promoting factors (NPFs) in the process of invagination from the cell surface through endocytosis.

132 injured membrane through caveolae, membrane invaginations from lipid rafts.

133 nt is sustained by thylakoid growth and that invaginations from the inner envelope membrane contribut

134 challenges, including large plasma membrane invaginations generated by rapid cell shrinkage.

135 anges in aging, as glandular-like epithelial invaginations (GLEIs) derived from ABSCs emerged exclusi

136 Caveolae are small membrane invaginations important for transendothelial albumin upt

137 ckdown embryos, and causes archenteron hyper-invagination in control embryos.

138 tebrates and vertebrates, including mesoderm invagination in Drosophila, neural crest migration in ve

139 We find that MyoII activation and invagination in each row of cells drives adhesion to the

140 sms needed to reproduce the formation of the invagination in silico.

141 enes are expressed and required for mesoderm invagination in the fruit fly Drosophila melanogaster bu

142 rins, apical spreading, MyoII activation and invagination in the next row.

143 phosphate was enriched at sites of cell wall invaginations in both the sur7 and pil1 lsp1 cells, indi

144 es (t-tubules) are uniquely-adapted membrane invaginations in cardiac myocytes that facilitate the sy

145 ccumulates within elaborate nuclear envelope invaginations in patient induced pluripotent stem cell (

146 Invaginations in the glial cell cytoplasm house the neur

147 Invaginations in the membranes of embryonic cells appear

148 transverse tubules are a system of membrane invaginations in ventricular cardiomyocytes which allow

149 Nuclear envelope invaginations incorporating SERCA1 in their outer nuclea

150 tening, chromatin stiffening, nuclear lamina invaginations, increase in nuclear height, and shrinkage

151 2/3 inhibition forms extended ER-interacting invaginations, indicating that sterol transfer contribut

152 al RdRPs occurs inside vesicle-like membrane invaginations induced by the recruitment of the viral Rd

153 Nuclear membranes can form large invaginations inside the nucleus; their specific roles s

154 ctomyosin ring (cytokinetic actomyosin ring) invagination; instead, it split into a double ring that

155 g direct transformation of broad and shallow invaginations into detached vesicles in BAR mutant yeast

156 The segmentation to visualize the cristae invaginations into the mitochondrial matrix was possible

157 ization of LEM domain proteins and extensive invaginations into the nuclear interior, but also impair

158 of multivesicular bodies where, by membrane invagination, intraluminal microvesicles carrying membra

159 ll elongation gradient remains when mesoderm invagination is blocked but is abolished in the absence

160 Invagination is blocked by inhibition of actin polymeriz

161 tected until fetal week 22 when bipolar cell invagination is present in the cone pedicle.

162 that apical constriction leading to endoderm invagination is the source of the extrinsic force contri

163 This suggested that endoderm invagination is the source of the tensile force.

164 id spherocylinder representing the endocytic invagination, is tightly constrained by experimental dat

165 rives the formation of flask-shaped membrane invaginations known as caveolae that participate in sign

166 caffolding protein caveolin to form membrane invaginations known as caveolae.

167 embrane of cardiac myocytes presents complex invaginations known as the transverse-axial tubular syst

168 en the bulk sarcolemmal surface and membrane invaginations known as transverse tubules (TT).

169 oligomers at sites of initiation of membrane invagination; LhaA associates with RCs, bacteriochloroph

170 actility in the cell contour, characteristic invaginations lined by actin bundles form between adjace

171 Caveolae are 50- to 80-nm membrane invaginations lined by cage-like polygonal structures [7

172 equestering of excess membrane in stabilized invaginations may effectively increase the cell membrane

173 support the vesicle germination and membrane invagination models of cristae formation.

174 ivary glands and teeth, we show that initial invagination occurs through coordinated vertical cell mo

175 Actin can also support the processes of invagination of a membrane segment into the cytoplasm, e

176 l expression, which controls the coordinated invagination of approximately 1,000 mesoderm cells durin

177 ctivation of the small GTPase Rap1 restricts invagination of both dorsal folds in an alpha-catenin-de

178 Invagination of epithelium into the surrounding mesenchy

179 In the absence of BG, inward invagination of GCP persists but is uncoupled from the f

180 nation process in the matrix, in addition to invagination of IBM.

181 Ileocolic intussusception is the invagination of ileum into the colon.

182 ces apical cell constrictions that drive the invagination of mesoderm and posterior gut primordia.

183 shape change linked to folding, bending and invagination of polarized epithelia.

184 mation of double-membraned liposomes via the invagination of single-membraned liposomes.

185 s in Myo5b KO mouse enterocytes form through invagination of the apical brush border membrane.

186 rom an ingression of individual cells to the invagination of the blastoderm epithelium.

187 diverse set of proteins that coordinate the invagination of the cell membrane and synthesis of cell

188 One of these is the flagellar pocket, an invagination of the cell membrane around the proximal en

189 determine how pulses are coordinated during invagination of the Drosophila ventral furrow.

190 Thickening and the subsequent invagination of the epithelium are an important initial

191 ived cAMP from pigment cells to control late invagination of the hindgut.

192 The divisome regulates the invagination of the inner membrane, cell wall synthesis,

193 nd fog expression foreshadow the coordinated invagination of the mesoderm at the onset of gastrulatio

194 The invagination of the mesoderm in the Drosophila melanogas

195 f the developing nasal cavity, which retards invagination of the nasal cavity, and thus appears to co

196 disease, originated from the failure in the invagination of the optic vesicle during the fetal perio

197 ion template is coiled inside a 30- to 90-nm invagination of the outer mitochondrial membrane, whose

198 gle flagellum whose base contains a bulblike invagination of the plasma membrane called the flagellar

199 erted by a polymerizing actin meshwork on an invagination of the plasma membrane during endocytosis i

200 his turgor pressure, however, may oppose the invagination of the plasma membrane needed for endocytos

201 dstage wild-type mouse MKs in a well-defined invagination of the plasma membrane reminiscent of the i

202 ng Drosophila melanogaster gastrulation, the invagination of the prospective mesoderm is driven by th

203 pore-less sensilla of the sacculus, a unique invagination of the third antennal segment.

204 Invagination of these rings produced improperly oriented

205 r follicle placode "budding" is initiated by invagination of Wnt-induced epithelium into the underlyi

206 s the presence of nanoscopic protrusions and invaginations of lower lipid order in plasma membranes,

207 meres in the perinuclear region and abnormal invaginations of nuclei were found ultrastructurally.

208 These spherular invaginations of outer mitochondrial membranes are packe

209 Caveolae are abundant flask-shaped invaginations of plasma membranes that buffer membrane t

210 tes in the meninges, which was pronounced in invaginations of the brain surface (sulci) and possibly

211 tes, caveolin is located predominantly along invaginations of the cell membrane known as t-tubules.

212 ular membranous vesicles that originate from invaginations of the cytoplasmic membrane.

213 hundreds of independent spherules that were invaginations of the ER membranes into the lumen.

214 Tubular cristae are formed via invaginations of the inner boundary membrane by a pathwa

215 ia have a characteristic ultrastructure with invaginations of the inner membrane called cristae that

216 Crista junctions (CJs) are tubular invaginations of the inner membrane of mitochondria that

217 nct from the large negative curvature of the invaginations of the inner mitochondrial membrane where

218 Finally, exocuticle rich invaginations of the occipital sutures are identified bo

219 Caveolae are bulb-shaped invaginations of the plasma membrane (PM) that undergo s

220 f caveolae, which are specialized lipid raft invaginations of the plasma membrane associated with cel

221 cells retrieve receptor clusters using large invaginations of the plasma membrane capped with clathri

222 in found in caveolae, which are cell surface invaginations of the plasma membrane that act as signali

223 Caveolae, small (60-100 nm) bulb-like invaginations of the plasma membrane, are comprised pred

224 r signaling complexes present in perinuclear invaginations of the plasma membrane.

225 (VCCs), which largely consist of convoluted invaginations of the PM.

226 The recruitment to plasma membrane invaginations of the protein endophilin is a temporally

227 t-system remodeling, particularly sheet-like invaginations of the sarcolemma.

228 tic novel phenotype consisting of sheet-like invaginations of the sarcolemma.

229 In mammalian ventricular cardiomyocytes, invaginations of the surface membrane form the transvers

230 ubules of mammalian ventricular myocytes are invaginations of the surface membrane.

231 dramatically reduced lacuna channel membrane invaginations offered a strong indication of reabsorptio

232 smembrane helices and a decameric c-ring and invaginations on either side of the membrane indicate th

233 Evidence of the epithelial invaginations on the cement glands supports the involvem

234 h signalling is necessary for, and promotes, invagination once suprabasal tissue is generated.

235 mitosis, cell intercalation, and neuroblast invagination or by forces generated by the actomyosin ca

236 e cytoplasm in the absence of outer membrane invagination or visible cell wall ingrowth.

237 induces lamellipodial protrusions instead of invaginations or filopodia-like structures.

238 tically dead mutant of KDM4B, rescue the ear invagination phenotype caused by KDM4B knockdown.

239 D) and impaired the formation of prophase NE invaginations (PNEIs), similar to microtubule depolymeri

240 The meso-scale model breaks up the invagination process into three stages: 1) initiation, w

241 ngolipids directly take part in the membrane invagination process.

242 nsion, implying an active involvement in the invagination process.

243 nt quite distinct from previously recognised invagination processes.

244 scale wave of Rho1-MyoII activation and cell invagination progresses anteriorly away from the primord

245 esis of these organs and of why they lead to invagination rather than simple tissue thickening.

246 The mechanism that controls the extent of invagination remains unknown.

247 R (F-BAR) proteins generate tubular membrane invaginations reminiscent of the megakaryocyte (MK) dema

248 Already this invagination requires the dynamin-like GTPase Vps1p and

249 The formation of these invaginations requires the function of Cdc42, and their

250 ensive brush border and basolateral membrane invaginations resembling those observed in vivo.

251 Ectopic invaginations resulted from medioapical myosin loss in n

252 recruitment to the necks of clathrin-coated invaginations resulting in impaired vesicle budding.

253 propose that surface detachment of membrane invaginations results from an ability of CADs to interfe

254 ects in transsynaptic adhesion, Schwann cell invagination/retraction, vesicle accumulation and acetyl

255 egment into the cytoplasm, elongation of the invagination, scission of the new vesicle from the plasm

256 c actin assembly, which facilitates membrane invagination/scission.

257 C.riparius is sufficient to invoke mesoderm invagination similar to D.melanogaster.

258 n contrast, the sur7 mutant formed cell wall invaginations similar to those for the pil1 lsp1 mutant

259 alis derives from vsx positive placodal-like invagination sites.

260 re similar than previously thought, membrane invagination speed and depth are two-fold greater in fis

261 Inhibiting the formation and release of the invaginations strongly interfered with bleb formation, c

262 actomyosin network connections during tissue invagination, suggesting that Myo-II pulses are required

263 n MK PPF via inhibition of the late-stage MK invagination system, podosome and PPF, and PP branching.

264 The model predicts forces orthogonal to the invagination that are consistent with formation of a fla

265 domains establishes the site for the upward invagination that initiates fission.

266 component of caveolae, small plasma membrane invaginations that are highly abundant in adipocytes.

267 ansion of the protrusion depends on membrane invaginations that are localized preferentially at the c

268 Caveolae are membrane invaginations that can sequester various signaling prote

269 frequently includes deep, branching tubular invaginations that form a dynamic nucleoplasmic reticulu

270 Initially, vacuoles shrink and generate deep invaginations that leave behind tubular structures in th

271 t the base of the crypts of Lieberkuhn, tiny invaginations that line the mucosal surface all along th

272 at lines the colonic crypt, test-tube shaped invaginations that punctuate the lining of the intestine

273 in assembly at the interface center, a large invagination, the actin-supported interface periphery as

274 een described as forming from two endodermal invaginations-the anterior intestinal portal (AIP) towar

275 the BAR domain protein Pil1, generates these invaginations through direct binding to lipids including

276 minal-C cells located at the distal prostate invagination tips (termed Dist-Luminal-C) exhibited grea

277 as the luminal progenitor cell population in invagination tips and suggests one of the potential cell

278 gers a rapid shape transition from a shallow invagination to a highly invaginated tubular structure.

279 y accounting for post-stratification placode invagination to bud stage.

280 embryonic day (E)10.5 stage of lens placode invagination to E12.5 lens primary fiber cell differenti

281 strulation, a higher number of cells undergo invagination to form the deep posterior dorsal fold, whe

282 nanoparticles that are enclosed by membrane invaginations to form magnetosomes so they are able to s

283 he necks of cargo-containing plasma membrane invaginations to radii at which the opposing segments sp

284 cell types develop extensive plasma membrane invaginations to serve a specific physiological function

285 cell envelope biosynthesis, causes membrane invaginations together with delocalisation of the cell w

286 he exocyst complex, induces tubular membrane invaginations toward the lumen of synthetic vesicles in

287 membrane adjacent to the outer membrane and invaginations toward the matrix, called cristae.

288 embryonic lens either at the time of placode invagination using the Le-Cre line or after initial lens

289 outlined basic structural features of these invaginations, very little is known about the mechanism

290 KDM4B play a critical role during inner ear invagination via modulating histone methylation of the d

291 Chloroplast envelope inner membrane invaginations were frequently found in close association

292 owth starts from the periphery as a membrane invagination, which grows radially inward like the shutt

293 of the ciliary plasma membrane indicating an invagination, which is likely a first step in disk forma

294 le premature mitotic entry inhibits mesoderm invagination, which relies on apical constriction, mitot

295 positive-strand RNA viruses form on membrane invaginations, which result from negative membrane curva

296 play a more general role in coordinating OM invagination with PG remodeling at the division site tha

297 sed intracellular compartments that fused to invaginations with access to the extracellular space.

298 tion is located at the base of the endocytic invagination, with the growing ends of filaments pointin

299 is compartmentalized to individual synaptic invaginations within a cone terminal, consistent with pr

300 myocardial crypts (ie, narrow, blood-filled invaginations within the LV wall) have been recognized i