ライフサイエンスコーパス: invariable

1 secondary structure features remained nearly invariable.

2 nsition to a "castration-resistant" state is invariable.

3 tasis and, until recently, was thought to be invariable.

4 currences in bortezomib-treated patients are invariable.

5 stituted by glutamate, but E63 appears to be invariable.

6 gles is likely influenced by the more rigid, invariable 3' and 5' flanking TT dinucleotide steps and

7 1*08, the transmission of DRB1*15 was almost invariable (37 transmissions to one non-transmission).

8 n of adenine by 2-amino purine (2-AP) at the invariable A small middle dotT base pair at the -11 posi

9 neural tube and lens vesicle [2]; PCD is an invariable accompaniment to these processes, but it is u

10 Dementia appeared to be an invariable accompaniment, although it could take a numbe

11 y 3 and approximately 1.7, respectively, but invariable action spectra and effective antenna sizes of

12 +) due to a direct contact from the N7 of an invariable adenosine.

13 Posterior leaflet tethering is invariable after mitral annuloplasty, rendering postoper

14 Deletion of invariable amino acid residues in a conserved domain of

15 Despite having almost invariable amino acid sequences in their principal DNA-b

16 nts of MacRPA3 by replacing each of the four invariable amino acids in the zinc finger with alanine.

17 lectins share a common sequence motif of 14 invariable and 18 highly conserved aa residues known as

18 49.7mg/l); whereas phenolic content remained invariable and ascorbate content peaked near S5 in both

19 us critical illness polyneuropathy is almost invariable and can be found up to 5 yrs after intensive

20 delta, epsilon, and zeta subunits, which are invariable and ensure signal transduction.

21 fection by Mycobacterium tuberculosis is not invariable and may depend on bacillary as well as host f

22 this, herpes simplex virus 1 (HSV-1) causes invariable and rapid lethality in STING-deficient (STING

23 (variable and flexible) with the C-terminal (invariable and rigid) parts of the Ca2+-binding loop.

24 Using this feature, we found that invariable and variable epigenetic states across cell ty

25 Furthermore, mutation of the invariable aspartic acid to asparagine in VEGFR-2 lowere

26 This revealed an invariable association of perifascicular atrophy with ca

27 vironmental conditions, despite being almost invariable at the morphological level.

28 only three positions where the amino acid is invariable between all the predicted proteins.

29 erated by either deleting or substituting an invariable C-terminal Ile(316), wedged into a hydrophobi

30 pes, but heterozygous pups used individually invariable call sequences with less complicated call typ

31 This two- to threefold invariable CAP stimulation appears to depend on the -45

32 OCT has allowed us to demonstrate the almost invariable coexistence of the bursa premacularis and spa

33 sive proteins, act redundantly to ensure the invariable combination of L1 and L2 postsynaptic element

34 with kinetics of binding that are relatively invariable compared to HH26, which is highly specific an

35 RESISTANT6 (AXR6), which encodes CULLIN1, an invariable component of the SCF complex.

36 SCF complexes consist of three invariable components, Skp1, Cul-1 (Cdc53 in yeast) and

37 Thus, the nucleosomal response is an invariable consequence of ERK and p38 but not JNK/SAPK a

38 ystemic inflammatory states and is an almost invariable consequence of septic shock.

39 cid receptor alpha) haploinsufficiency is an invariable consequence of t(15;17)(q22;q21) translocatio

40 ogressive reduction in firing rate is not an invariable consequence of the fatigue associated with su

41 SMARCC2 (BAF170) is one of the invariable core subunits of the ATP-dependent chromatin

42 Purely invariable CpGs display a bimodal distribution with enri

43 f instead of ELR (Glu-Leu-Arg) preceding the invariable CXC motif.

44 in that carries the additional loop KSGKPLH, invariable cysteine (Cys) residues Cys-40 and Cys-168, a

45 Interestingly, and despite the invariable distribution of other relevant marker protein

46 this peptide, indicating that the C-terminal invariable domain is immunodominant.

47 oduced the entire sequence of the C-terminal invariable domain of VlsE from B. burgdorferi strain B31

48 oduced the entire sequence of the C-terminal invariable domain of VlsE was conjugated to the carrier

49 We concluded that the C-terminal invariable domain was exposed at the antigen's surface b

50 spirochetes, indicating that the C-terminal invariable domain was exposed at the antigen's surface.

51 Mouse antibody to the C-terminal invariable domain was not able to confer protection agai

52 and antigenic conservation of the C-terminal invariable domain were assessed.

53 VlsE contains two invariable domains and a variable one that includes six

54 It is not known if these two invariable domains are exposed at the surface of either

55 gen of Borrelia burgdorferi, consists of two invariable domains at the amino and carboxyl termini and

56 ntigen of Borrelia burgdorferi, contains two invariable domains located at the amino and carboxyl ter

57 munodominant variable domain and one or more invariable domains that are not antigenic.

58 irochete, Borrelia burgdorferi, contains two invariable domains, at the amino and carboxyl termini, r

59 spirochete, also contains both variable and invariable domains.

60 propagating ruptures are largely similar and invariable during the rupture process regardless of the

61 d the Ag-presenting molecule and do so in an invariable "end-to-end" manner.

62 ly robust; their expression is controlled by invariable expression programs.

63 However, in almost an invariable fashion, cancers eventually regrow in the pre

64 Eosinophilia is a common, but not invariable, feature of these diseases.

65 t activation and microthrombus formation are invariable features of xenograft rejection and the vascu

66 Hypofrontality is a common but not invariable finding in schizophrenia.

67 ell requirement for these interactions is an invariable finding, however, is less clear.

68 evealed a 2.9-Mb region that was essentially invariable for all 31 8.1 AHs.

69 ticulum from building blocks that include an invariable glycerol backbone and variable fatty acyl cha

70 er of intragenic recombination events nearly invariable in a given population, suggesting that the re

71 lpha,omega-dihydroxy fatty alcohols remained invariable in both races, barring a minor (< 10%; p < 0.

72 Intractable seizures are invariable in children with ISOD; however, to our knowle

73 Cervical number is nearly invariable in most mammals, and numbers of thoracolumbar

74 However, chirality is usually an invariable inherent property of a given material that ca

75 Nevertheless, instead of being an invariable intrinsic property of each FRET pair, the fra

76 hromosome, believed to be nonrecombining and invariable, is a classic example of the effect of natura

77 pathophysiology of sepsis that includes the invariable loss of the host's microbiome with the emerge

78 ype XA21 and the kinase-dead mutant with the invariable Lys736 residue mutated to glutamic acid were

79 ow that Fagradalsfjall delta(18)O values are invariable (mean delta(18)O = 5.4 +/- 0.3 per mille 2 SD

80 mice resulted in respiratory dysfunction and invariable neonatal death, related to the complete absen

81 rom a single point mutation, which alters an invariable nucleotide in the splice donor site after exo

82 kemia cells, a G1 arrest is a common, if not invariable, occurence and takes place after the appearan

83 An important caveat is the invariable occurrence of GVHD that precludes long-term s

84 FTLD-TDP subtypes by 3 unique features: (1) invariable onset in the anterior temporal lobe (ATL), (2

85 e neutral theory where most sites are either invariable or neutral.

86 any inflammatory genes, repression is not an invariable outcome.

87 a large core of microbial taxa that remained invariable over 13 mo, thereby underlining the long-term

88 infrared spectra of TiO(2)-adsorbed OFX were invariable over a wide concentration and pH range and we

89 als form tetrad synapses that incorporate an invariable pair of postsynaptic elements, one each from

90 osition and cognitive dysfunction, which are invariable pathological features in patients with Alzhei

91 As cerebral amyloid angiopathy is an almost invariable pathological finding in Alzheimer's disease,

92 for approximately 12 h, and then display an invariable pattern of migration to distinct regions of t

93 Each single mutation at an invariable position resulted in a protein containing les

94 proteins harboring a mutation at one of the invariable positions bound to single-stranded DNA weakly

95 of protein structure, mutations at the other invariable positions led to larger structural changes.

96 However, with the nearly invariable progression of this disease to androgen indep

97 ia, is characterized by its insidious onset, invariable progression to chronic renal failure and a st

98 (0.5)O(2) ferroelectric capacitors is not an invariable property but, in fact, can be intrinsically c

99 ynthetic peptide (C(6)), based on the 26-mer invariable region (IR(6)) of the variable surface antige

100 Invariable region (IR)(6), an immunodominant conserved r

101 the full-length dbpA gene combined with the invariable region 6 of the vlsE gene (DbpA/C6) and (b) t

102 rabbit antibody raised against the conserved invariable region 6 of VlsE, as assessed by indirect imm

103 peptide (C6) that reproduces the sequence of invariable region 6 of VlsE, the antigenic variation pro

104 ked immunosorbent assay antigens to map this invariable region in infected monkeys, mice, and human L

105 In contrast, antibody to the more conserved invariable region IR(6) of VlsE was present in all of th

106 Only one invariable region, IR(6), was antigenic in all animals o

107 contains a 26-amino-acid-long immunodominant invariable region, IR(6).

108 ithin the VlsE variable domain there are six invariable regions (IR1-6) that together amount to half

109 iable one that includes six variable and six invariable regions (IRs).

110 for an antibody response to each of the six invariable regions (IRs; i.e., IR(1) to IR(6)) of VlsE,

111 Short, nonantigenic, invariable regions also may be present within the variab

112 resent study, the antigenicity of all of the invariable regions in B. burgdorferi-infected monkeys, h

113 Surprisingly, unlike the invariable regions of variable major protein, variant su

114 The latter contains six invariable regions, IR(1) to IR(6), and six variable reg

115 Leu349 was another invariable residue.

116 B. germanica GST contained 18 of the 26 invariable residues identified in mammalian GST by x-ray

117 Kinetic modeling yielded invariable second-order rate constants and increasing co

118 -shift conservation between fibrils revealed invariable secondary-structure properties, however, with

119 ing adaptive phenotypic evolution depends on invariable selection gradients and on the stability of t

120 ds allowing for intersite rate variation and invariable sites confirms that centrohelid heliozoa are

121 This invariable stimulation is by two- to threefold and occur

122 nition site and the nuclease active site are invariable, suggesting potential targets for antivirals

123 Cys111 is the invariable third half-cystine of the second complement c

124 le thresholds persist longer than those with invariable thresholds because inactive workers perform t

125 rt wavelength band (460 nm) was found almost invariable throughout the titrations.

126 l to incorporate other risk factors, and are invariable to patient preference.

127 Fertilizer release rates were largely invariable to pH and NPK loading but were tunable over 3

128 r alone or in collaboration with ECNA) is an invariable trigger of paroxysmal atrial tachyarrhythmias

129 ostly in numerous ways of extensions from an invariable trimannosyl core and terminal modifications.

130 phasic response to glucose were essentially invariable up to passage 38 but thereafter declined.

131 he plasma membrane proteome remained largely invariable, we observed pronounced alterations in severa

132 ro-adapted rabbit and dog BSE agent remained invariable with respect to the original cattle BSE prion