ライフサイエンスコーパス: investigative

1 lia is rapidly growing because of a surge of investigative activity.

2 Among the investigative AD therapies in clinical trials are severa

3 nce during recent decades and identifies the investigative agendas that were dominant or ascendant du

4 Our results inform the future selection of investigative agents for a UK clinical platform study.

5 gnificant advances that have occurred in the investigative and clinical approaches to lymphedema, par

6 Esophageal motor function remains of investigative and clinical interest because of its relev

7 This article provides both investigative and clinical nuclear medicine physicians w

8 nd is opening many exciting opportunities in investigative and diagnostic pathology.

9 However, investigative and drug development efforts should be div

10 The Gemina system provides an integrated investigative and geospatial surveillance system connect

11 ould be helped if a practitioner followed an investigative and management algorithm, and whether outc

12 If the finding is replicated, orchestrated investigative and policy efforts could systematically im

13 Orchestrated investigative and policy efforts could systematically in

14 Although control females were investigative and prosocial (e.g., affiliative proximity

15 nd bacterial pathogens, thereby providing an investigative and surveillance tool describing the Who [

16 smosis and may guide individual decisions on investigative and therapeutic options.

17 Future research may provide alternative investigative and treatment strategies to improve the ac

18 for Esr1(+) neurons in both the appetitive (investigative) and the consummatory phases of social int

19 ovate in other behavioral domains (foraging, investigative, and self-directed behaviors).

20 uction of designer platelets for diagnostic, investigative, and, ultimately, therapeutic use.

21 formation, a target of several approved and investigative anti-cancer agents.

22 In addition, we describe a unique investigative approach for the discovery of genetic alte

23 , systemic disorder requiring a multipronged investigative approach in both humans and animal models

24 A comprehensive investigative approach in Muzaffarpur led to timely publ

25 The investigative approach proceeds via numerical solution o

26 This new and systematic investigative approach should decrease inconsistencies i

27 This investigative approach simultaneously assessed the utili

28 o reconcile these literatures, we applied an investigative approach to the brain-body interactions at

29 -fidelity intracellular electrophysiological investigative approach.

30 gered the development of a novel data-driven investigative approach.

31 Ultimately, we can envisage new investigative approaches and therapeutic options that wi

32 the high evolutionary conservation of pain, investigative approaches from Drosophila mutagenesis to

33 s affecting marine ecosystems, but different investigative approaches in physical, chemical, and biol

34 Uniform clinical and laboratory investigative approaches maximize disease diagnosis.

35 actable problem, resistant to a multitude of investigative approaches over centuries.

36 ed topography of Tpt should be factored into investigative approaches that consider this region of th

37 In addition, our investigative approaches to identify conserved lncRNA an

38 rventions for muscle atrophy and for further investigative areas into insulin insensitivity and type

39 gnificantly and are a useful addition to the investigative armamentarium.

40 nd qmab/pembro plus lenva, but not the other investigative arms.

41 inflammatory responses, have received little investigative attention compared with macrophages from o

42 n elusive goal that have received widespread investigative attention in the areas of environmental co

43 ogressive CKD and aging kidney has attracted investigative attention that revealed senescent cells an

44 mucosal HIV-1 infection has received little investigative attention.

45 ns, but its pathogenesis has received little investigative attention.

46 ecreting CD8+ T cells have not received much investigative attention.

47 fic insights have opened new therapeutic and investigative avenues for conditions that still lack eff

48 grams and epigenetic regulation, opening new investigative avenues on these critical cell elements in

49 Males exhibit more wrestling and less investigative behavior during RI, find aggression reward

50 , with a marked shift from intruder-directed investigative behavior to very high levels of aggressive

51 In Experiment 1, subjects directed most investigative behavior toward scents from unfamiliar hye

52 vote more of their innovations repertoire to investigative behaviors and social bonding behaviors and

53 , alternate between aggressive behaviors and investigative behaviors more readily during RI, however,

54 In conclusion, investigative biopsies provide data-rich insight into di

55 sis; however, the feasibility and utility of investigative biopsies to monitor treatment response rem

56 r highlights the importance of expanding the investigative boundaries of the microbial ecology of bio

57 This review of investigative bronchoscopy and bronchoprovocation could

58 roup reaffirmed the scientific importance of investigative bronchoscopy and bronchoprovocation, even

59 Interest in clinical investigative careers has declined over the past 2 decad

60 m, phase 2 RAGNAR study was conducted at 156 investigative centres (hospitals or oncology practices t

61 -label, phase 2 trial being conducted at 109 investigative centres in ten countries worldwide.

62 ct HCM and DCM phenotypes will be the future investigative challenge.

63 with the data used in the analysis, and the investigative committee was unable to validate the data

64 in GDD implantation flourished, so too, did investigative comparison between devices; which includes

65 is paper, we propose a method to measure the investigative content of news articles based on article

66 8 years and 17 patients >18 years) underwent investigative CT (at minimal exposure settings combined

67 Mortuary data were supplemented with investigative data extracted from police dockets during

68 The investigative data related to this system is very encour

69 ce of electrocardiography and other clinical investigative data, and unrecorded overseas vaccination

70 lar disease, but its use in the clinical and investigative decision making is limited by the characte

71 Investigative dermatologists are needed to drive and ori

72 For many years, The Journal of Investigative Dermatology (JID) has been a leader in our

73 the genetic mechanisms of disease.Journal of Investigative Dermatology 128, 2753-2759; doi:10.1038/ji

74 a, BISS and DLQI assessment tools.Journal of Investigative Dermatology accepted article preview onlin

75 to the observed cancer resistance.Journal of Investigative Dermatology accepted article preview onlin

76 matitis via the PAR2-TSLP pathway.Journal of Investigative Dermatology accepted article preview onlin

77 d therapeutic applications in man.Journal of Investigative Dermatology accepted article preview onlin

78 iscuss examples of CRISPR genetic screens in investigative dermatology and how they may be used to an

79 that Rothman had a seismic impact on moving investigative dermatology from a medical backwater to a

80 A new report in this issue of Journal of Investigative Dermatology reveals a role for IL-17 and I

81 , American Board of Dermatology, Society for Investigative Dermatology, and American Academy of Derma

82 In their new article in the Journal of Investigative Dermatology, Boudra et al.

83 s mentioned were published in the Journal of Investigative Dermatology, but many articles from the br

84 In their new article in the Journal of Investigative Dermatology, Dzung et al.

85 Schwager et al., in this issue of Journal of Investigative Dermatology, have examined the role of imm

86 has the power to lead to key discoveries in investigative dermatology, including but not limited to

87 In this issue of the Journal of Investigative Dermatology, Meylan et al. present evidenc

88 currently scarcely used within the field of investigative dermatology, we aim to highlight CyTOF's u

89 pportunity that exists for future studies in investigative dermatology.

90 ng discovery in both basic and translational investigative dermatology.

91 IC has the ability to enhance diagnostic and investigative detection of disease-associated PrP(RES) i

92 ng in suboptimal clinical care and/or future investigative directions.

93 al Cancer Institute's clinicaltrials.gov and Investigative Drug Branch databases.

94 A surge of investigative effort has been directed toward the preven

95 Much investigative effort is focusing on telomere dynamics wi

96 lood coagulation and has been the subject of investigative effort, speculation, and controversy.

97 erfusion injury are areas of intense current investigative effort.

98 immune disease remains a focus of increasing investigative effort.

99 oporation) remain obscure despite decades of investigative effort.

100 miRNA is still in its early stages, ongoing investigative efforts and the development of new technol

101 function are important areas to concentrate investigative efforts and therapeutic development.

102 are available for cure of the infection, so investigative efforts are focusing on cost-effectiveness

103 f perovskite solar cells have been achieved, investigative efforts have turned to understand other ke

104 idering sex as a variable and for additional investigative efforts in long term neurodevelopmental ou

105 Current research and clinical investigative efforts involving methods for more effecti

106 Finally, given that PALF is a rare disease, investigative efforts must include broad multicenter col

107 e intuition can be a poor guide in directing investigative efforts of these non-linear and interconne

108 77)Lu-PSMA-617 treatment to date and explore investigative efforts to leverage radiopharmaceutical th

109 of a chronic alloimmune response has shifted investigative efforts toward CNI-free regimens.

110 The ongoing global investigative efforts toward understanding AF are also d

111 Despite enormous investigative efforts, the pathological basis for Alzhei

112 el of severity, are a major focus of current investigative efforts.

113 ly defined, but has been the topic of recent investigative efforts.

114 ervosa remains controversial and begs future investigative efforts.

115 document, "outcomes research" is defined as investigative endeavors that generate knowledge to impro

116 ework for weighing predictions against other investigative evidence using calibration, and bring our

117 egimens in Psoriasis) and FIXTURE (Full Year Investigative Examination of Secukinumab vs. Etanercept

118 The research group had prior clinical and investigative experience in this setting, and used multi

119 Investigative exploration and foraging leading to food c

120 genetic and epidemiological data allowed for investigative fact-checking and verified patient-reporte

121 are discussed as a means of propelling this investigative field forward.

122 us on prompt diagnosis based on clinical and investigative findings but should also reflect a patient

123 In vertebrates, the investigative focus has primarily been on serine, threon

124 ublic health problem and warrants a specific investigative focus on improved risk stratification and

125 Investigative genetic genealogy (IGG) has helped to reso

126 The investigative goal was to experimentally define in vitro

127 Our investigative group developed recombinant, autoreactive,

128 The investigative group included patients with lung nodules

129 kers can be provided in a multisite oncology investigative group setting.

130 phenotypes and phenotypes reported by other investigative groups (e.g., Sepsis Response Signature [S

131 Several investigative groups have applied genetic and genomic ap

132 ifferences in mania symptom profiles between investigative groups may be, in part, due to whether chi

133 This has prompted many investigative groups to explore whether such a presentat

134 oal will require collaboration among various investigative groups, and validation in both existing da

135 the more positive results reported by other investigative groups.

136 sive, despite the intense efforts of several investigative groups.

137 gain a new tool of substantial clinical and investigative importance that could significantly change

138 s represents a novel area warranting greater investigative interest in the prevention and/or treatmen

139 The major areas of investigative interest include patient selection, anesth

140 xperiences prior to an in-depth, more formal investigative interview.

141 ificantly improved event recall during later investigative interviews versus the Control.

142 public health advocacy organizations and an investigative journalism series published in 2012 in the

143 " (FPP), drew on both scientific methods and investigative journalism techniques such as open-source

144 The American Journal of Pathology and other investigative journals during the past century, their im

145 kville, Md., and the Research Diagnostic and Investigative Laboratory, Columbia, Mo.

146 es or genetic factors, could provide helpful investigative leads in forensic casework.

147 mic iron overload remains at the preclinical investigative level and is complicated by the risk of ad

148 the lenses were switched between eyes and an investigative lubricant was instilled after 4 hours of l

149 A key investigative method is to replicate the sensory apparat

150 soil and groundwater, augmenting traditional investigative methods that are time-consuming, resource-

151 stry requires the development of appropriate investigative methods to enable less conservative and mo

152 with invasive infection by using genome-wide investigative methods would provide new insight into thi

153 re complex techniques could represent better investigative methods, but their uptake in cartilage res

154 partially due to the paucity of appropriate investigative methods.

155 very and detection have emerged as important investigative methods.

156 re is a need for a non-invasive and accurate investigative modality for DMD.

157 pancreatic beta-cell line can be used as an investigative model for refractoriness of glucose-induce

158 linicopathologic phenotype makes it an ideal investigative model to examine genetic processes that ma

159 h biclonal gammopathy multiple myeloma as an investigative model, the genetic and epigenetic alterati

160 s played a major role in my contributions to investigative nephrology that range from basic mechanism

161 a discussion of support for team research in investigative neuroscience at different stages and on va

162 now require safety data on hERG channels for investigative new drug (IND) applications.

163 dispositions that was manifested through an investigative, non-judging, analytic stance, a focus on

164 a dominant scientific disposition showing an investigative, non-judging, analytic stance, a focus on

165 hest citations (9509 citations), followed by Investigative Ophthalmology & Visual Science (202 public

166 halmology, British Journal of Ophthalmology, Investigative Ophthalmology & Visual Science, JAMA Ophth

167 This report identifies a number of investigative opportunities for significantly reducing t

168 Results: The committee identified several investigative opportunities to advance the care of patie

169 ial and sporadic cases of ALS provides a new investigative opportunity to shed light on both mechanis

170 Consequently, investigative (or mechanistic) toxicology has been gaini

171 vivo with unexpected features, opening a new investigative path to study the human CD1 system.

172 or to The American Journal of Pathology, the investigative pathologist S.

173 or to The American Journal of Pathology, the investigative pathologist S. Burt Wolbach unambiguously

174 ults while conducting large-scale studies in investigative pathology and oncology.

175 xciting new findings to the attention of the investigative pathology community.

176 as presented during the American Society for Investigative Pathology Rous-Whipple Award Lecture 2021.

177 Expectedly, IMC will change the landscape of investigative pathology, particularly when used in coord

178 ted, Wolbach's tour-de-force work epitomized investigative pathology.

179 Following a similar investigative pathway, studies that show the importance

180 he utility of human cerebral organoids as an investigative platform for studying the effects of KCNJ1

181 PMO compounds have powerful therapeutic and investigative potential toward coronavirus infection.

182 aw enforcement agencies with broad civil and investigative powers to enable the government to interve

183 sis is a low threshold of suspicion; several investigative procedures can be used to confirm the diag

184 nt a stand-alone test or an adjunct to other investigative procedures for detecting cancer.

185 Investigative procedures were approved by Henry Ford Hum

186 self-blame and feelings of vulnerability to investigative procedures were reported.

187 or request meetings with the oncologist and investigative procedures.

188 Sepetaprost is a novel investigative prodrug, the active form of which is a dua

189 receptors hold considerable therapeutic and investigative promise.

190 The median effective dose for the investigative protocol was 0.04 mSv (95% confidence inte

191 ial evidence in criminal and civil cases for investigative purposes.

192 y, we have discovered, using a comprehensive investigative regimen, a novel and tissue-specific role

193 fferences were also observed within the same investigative region: CA1 was characterized by low capil

194 The Stroke Investigative Research and Educational Network (SIREN) i

195 ience and medicine, rapidly expanding beyond investigative research to drug discovery and development

196 ned over 4 decades of patient care, clinical investigative research, and surgical education.

197 essionals to better prioritize their limited investigative resources and take appropriate regulatory

198 lthough the observations illustrate a novel, investigative role for these compounds in the study of C

199 Using an inclusive investigative scheme, we here report that upregulated Cl

200 tal analyses, reactor model simulations, and investigative science techniques were used to provide in

201 se was developed to expose undergraduates to investigative science.

202 grative and clinical physiology by its broad investigative scope of basic research to community healt

203 al preparations may broaden its clinical and investigative significance.

204 Investigative site staff, people directly involved with

205 s, keys, phones, or handbags are found at an investigative site.

206 Patients were enrolled from 124 investigative sites (hospitals, clinics, and academic ce

207 open-label, randomised phase 3 study at 184 investigative sites in 26 countries.

208 Participants were recruited from 45 investigative sites in the United States and Canada and

209 their probability of defensive bunching and investigative smelling following playbacks of Maasai voi

210 dation to realize the full potential of this investigative space.

211 This initial investigative stage demonstrates the feasibility and saf

212 ical element in reproductive behavior is the investigative stage, which in mice and many other specie

213 The first investigative step showed colocalization of uromodulin w

214 In the third investigative step, none of 11 uromodulin-/- knockout mi

215 ucts, and (ii) suggest priorities for future investigative steps that will bring our knowledge of fat

216 This will require novel investigative strategies such as the use of historic con

217 A variety of investigative strategies, including manipulation of surf

218 In this Opinion, we highlight various investigative strategies, used in parallel by multiple i

219 ht be worth consideration in future HIV-cure investigative strategies.

220 lections, have facilitated a systems biology investigative strategy designed to enhance and accelerat

221 This investigative strategy may have general application for

222 In this study, we pursued a new investigative strategy that emphasizes mediators promoti

223 The investigative strategy that Vaesen uses presumes that co

224 active site, is a promising therapeutic and investigative strategy to mitigate and study diseases.

225 owever, bridging the gap between these basic investigative studies and clinical gene therapy remains

226 re will likely be a commensurate increase in investigative studies highlighting minority specific hea

227 n applied to rat urine samples obtained from investigative studies on the effects of acute 2-bromophe

228 physiologically relevant and warrants future investigative studies.

229 Here, we report an investigative study of a strategically designed library

230 IOPED II criteria and 2 used the Prospective Investigative Study of Pulmonary Embolism Diagnosis (PIS

231 Accordingly, this investigative study suggests that certain miRNAs are bio

232 n provide probative associative evidence and investigative support.

233 In this article, the notion of an investigative surgeon is explored, defining the role and

234 Animal models are key investigative systems because major confounding variable

235 ent public health problems and for which the investigative team does much of its work in the field (i

236 , that there is a written agreement that the investigative team has the freedom and obligation to att

237 uality by using predefined criteria, and the investigative team jointly graded the overall strength o

238 It is often valuable to the investigative team that is trying to trace back the belo

239 gulation was achieved by a multidisciplinary investigative team using two research methods and three

240 a from 5 randomized clinical trials led by 1 investigative team were combined.

241 described and illustrated by four different investigative teams.

242 ular system is now a well-recognized primary investigative technique for many conditions of structura

243 By using an investigative technique termed the five Ws (who, what, w

244 c radical cystectomy should be considered an investigative technique, and potential candidates for th

245 In addition, new investigative techniques have been developed, which may

246 Advances in in vivo investigative techniques have made it possible to quanti

247 Two contrasting investigative techniques provided evidence consistent wi

248 eous assumptions concerning that revealed by investigative techniques such as transcranial magnetic s

249 n in 3 has been achieved by a combination of investigative techniques that include synchrotron resona

250 Therefore, investigative techniques that rely on samples derived fr

251 cores the necessity of using a wide range of investigative techniques to link gene expression and phe

252 Novel investigative techniques will likely further improve our

253 e need for future research integrating novel investigative techniques.

254 h CTLA-4-Ig has the potential to serve as an investigative therapeutic tool in patients with PBC.

255 ythropoiesis, giving rise to a promising new investigative therapy.

256 ere, we go beyond using this technique as an investigative tool and focus on its potential to activel

257 We conclude that MRI is a powerful investigative tool capable of resolving lamina-specific

258 E-MAP represents a new investigative tool for analyzing the role of chronic ant

259 e numbers of samples provides a powerful new investigative tool for diagnostic, epidemiologic, and ba

260 shes N-type inactivation, it can serve as an investigative tool for functional and pharmacological st

261 dent analyses and will serve as an important investigative tool for primate brain imaging research.

262 (QCM-D) with a double aim, specifically, as investigative tool for spacers monolayer assembling and

263 ating the applicability of this method as an investigative tool for stabilizers.

264 ge to some practitioners, remains a valuable investigative tool for the specialists in paediatric neu

265 18F-FDG, PET/CT is rapidly becoming the key investigative tool for the staging and assessment of can

266 ic potential, are proving to be an important investigative tool for understanding the function of Bcl

267 equences for the application of garnet as an investigative tool in a broad range of geological enviro

268 This validates the use of axotomy as an investigative tool in understanding the role of peripher

269 nchymal cells' biology has been an important investigative tool to maximize bone regeneration through

270 ic application in mind are also useful as an investigative tool to reveal associations between specif

271 iocarbon ((14)C) measurements offer a unique investigative tool to study methane emissions by identif

272 Mathematical models provide an alternative investigative tool, and many have been developed to expl

273 In addition to the function as an investigative tool, these two types of modification may

274 rties and gives support to TVS as a valuable investigative tool.

275 for a revival, thanks to the development of investigative tools and nanotechnology-based solutions.

276 ish that kisspeptin antagonists are powerful investigative tools and set the scene for more extensive

277 ot have been captured yet because the proper investigative tools are not yet readily available.

278 evolves, advanced chemical and technological investigative tools are required to make sense of this i

279 ic stroke treatment, as well as their use as investigative tools for probing complement-dependent pat

280 g examined in increasing detail with diverse investigative tools in a variety of cell types, particul

281 ple immunogenetics of the CD1 system and new investigative tools to measure T-cell responses in human

282 ver the past decade, the availability of new investigative tools, including genetically modified mous

283 nes exist in these diseases and can serve as investigative tools.

284 new avenues for the development of reliable investigative tools.

285 e disease in studies utilizing bronchoscopic investigative tools.

286 Current investigative topics are discussed in this paper.

287 nological developments, based on a survey of investigative toxicologists from 14 European-based mediu

288 Based on a thorough investigative toxicology and clinical pathology analysis

289 Other investigative treatment approaches, including the use of

290 lead-in of ~10 participants occurred for all investigative treatments before randomization.

291 d CDK6 are now commonly used as approved and investigative treatments in breast cancer, as well as se

292 The recent investigative trend with respect to cancer has continued

293 for clinical monitoring and as an outcome in investigative trials.

294 phosphosite prediction, allowing for greater investigative utility and enabling substrate predictions

295 Little investigative work has been performed on supply manageme

296 stituents and functional groups, as well the investigative work on the mechanistic pathway.

297 Respondents associated investigative work with reduced earnings, a perception v

298 post-injury and post-treatment frames future investigative work.

299 el therapies and lay a foundation for future investigative work.

300 rs choose the most suitable models for their investigative work.-Liu, C.-H., Wang, Z., Sun, Y., Chen,