ライフサイエンスコーパス: involve

1 interact, less is known about the mechanisms involved.

2 n the structure and dynamics of the partners involved.

3 catalytic reactions where gas consumption is involved.

4 ve stress sensing appears to be a key factor involved.

5 at do we know about the neuronal populations involved?

6 tional substrate preparation procedure which involves (1) a modified substrate cleaning procedure and

7 'Observation study' involved 15 nurse prescriber and 15 patient group direct

8 At least 2 prospective clinical trials involving (177)Lu-PSMA agents are under way that will li

9 igated in a phase 2A study of RV3-BB vaccine involving 46 individuals in Dunedin, New Zealand, during

10 Risk factors for early transient rhinitis involve a combination of genetic and early environmental

11 Interactions between disordered proteins involve a wide range of changes in the structure and dyn

12 The most recent introgression event involved a massive and asymmetrical movement of genes fr

13 This involved a new ephaptic coupling, in which an excitatory

14 osmoticant agent suggest that channel gating involves a change in solute-inaccessible volume in the C

15 The pivotal one involves a resolution, through the quinine- or quinidine

16 The pathophysiology is complex and involves a strong genetic predisposition, epidermal dysf

17 ain signaling pathway can confer bistability involves a substantial amount of hypothesis testing.

18 ractice for training classification deepnets involves a terminal phase of training (TPT), which begin

19 This photoactivation involves a unique series of structural changes which ter

20 (4), O)(C, N, Ph) formed by P-stereomutation involving a M(B2) permutational mechanism (Channel B).

21 ngle linear sequence for this transformation involving a sigma complex and oxidative cleavage transit

22 hanced P-TEFb occupancy via a mechanism that involved activation of ATR and ATM and induction of NF-k

23 The pathogenesis of ASD is not known, but it involves activation of microglia.

24 ll death and inflammation through mechanisms involving activation of the inflammasome in macrophages.

25 were randomized to treatment of the six most involved airways in the first session (guided group) or

26 is of the progressing reaction shows that it involves an initial allylic substitution to form a new M

27 under mild metallaphotoredox conditions and involves an unprecedented decarboxylative radical additi

28 The lungs are the main organ involved, and chest X-rays, whether obtained in conventi

29 ion, leading to liver injury, by a mechanism involving AQP3-mediated H(2)O(2) transport.

30 t the metabolic connections and requirements involved are largely unknown.

31 the downstream signal transduction pathways involved are poorly characterised.

32 omplex and highly dynamical chemical process involves assembly and disassembly of many molecules in m

33 ielded almost identical mass spectra as APCI involving atmospheric pressure conditions, the presence

34 quantum mechanical tunneling (QMT) chemistry involving atoms heavier than hydrogen was considered unr

35 tes, apparently by promoting oligomerization involving binding to the C-terminal region.

36 to describe the evolution of processes that involve blending of compounds.

37 t on telomeric DSB repair and that this role involves both telomere cohesion and a DAXX-dependent pat

38 stallographic study (12 crystal structures), involving both CA II and a soluble CA IX mimetic (CA IX-

39 thermal fluids suggests a long reaction path involving both mafic and ultramafic lithologies.

40 hondrial matrix import for cPMP biosynthesis involving both proteins.

41 ism for growth inhibition does not, however, involve canonical roles as part of the RISC; rather, AGO

42 ral, and it appears that evolutionary change involved changes in protein-protein interactions to favo

43 w that inhibition of HIV-1 maturation by BVM involves changes in structure and dynamics that are surp

44 anced photoconduction, a complicated process involving charge generation and recombination in the tim

45 tients with RCC and combinatorial approaches involving checkpoint blockade are now standard of care i

46 r analyte detection that, in many instances, involve chemical modification of samples prior to analys

47 Conjugate PK assay strategies for these ADCs involve cleavage with cathepsin B or papain to release a

48 we have identified a gene regulatory pathway involving CsCLV3, CsWUS, CsFUL1(A) and CsARF14 in determ

49 uristic models for the tri-exponential decay involving defects are discussed.

50 pathic pulmonary fibrosis is a fatal disease involving destruction of the lung alveolar structure.

51 These settings involve different inheritance patterns, time scales, chr

52 Further studies are needed, involving different types and sources of fiber.

53 Cellular regulation of protein functions involves differential gene expressions, post-translation

54 ings show that a parsimonious mechanism that involves differential motility is sufficient to explain

55 cancer immunity, and in anticancer therapies involving DNA damage agents.

56 in, we have thoroughly studied the chemistry involving dual-emission persistent luminescence nanopart

57 The pathophysiology of visual symptoms might involve dysfunctional visual cortex.

58 Interspecies virus transmission involving economically important pollinators, including

59 Microcystis involved ED_co-occurrences are in important topological

60 .1, TCF3, and OCT2 transcription factors and involved elevated MYD88/TLR pathway activity.

61 Two major mechanism hypotheses, both involving ESAA relief, were explored through quantum che

62 A focus in recent decades has involved examining the potential causal impact of educat

63 The simple and fast protocol involves for the first time the use of micromagnetic imm

64 by GPBAR1 agonism was promoter dependent and involved FOXO1.

65 so observed during grasping movements, which involve fundamentally different patterns of kinematics a

66 Future work will involve further exploring metabolomic profiles of human

67 ey processes of intercellular communication, involving gap junctions, extracellular vesicles, and tun

68 hophysiology of pediatric anxiety appears to involve greater capture of attention to salient stimuli,

69 o steady-state and transient kinetic studies involving H/D and (13)C/(12)C exchange, coupled with ope

70 on of human DBC1 in regulating ELL stability involving HDAC3, p300, and Siah1.

71 paired threat learning, pathological anxiety involves heightened skin conductance response to potenti

72 of DBDI-MS and potentially other ion sources involving high voltage waveforms.

73 e IL18-IL18RAP axis and antigen presentation involving HLA-DRB1, which might help to identify potenti

74 Cervical screening involved HPV testing at age 35 years, or at ages 35 year

75 The technology involves HSPC mobilization and intravenous injection of

76 Different rice treatments were involved i.e. three soaking times (0, 15, and 30 min), t

77 Modelling involves identifying typhoon track vectors, clustering v

78 NAs and their target mRNAs were predicted to involve in synthesis of melanin, carotenoid or tetrapyrr

79 tion was most reduced for initiation factors involved in 40S scanning (eukaryotic initiation factor 4

80 us receptor-like kinase (CrRLK1L) and others involved in abiotic stress response.

81 arge number of physical and chemical factors involved in achieving fine control of Li electrodepositi

82 , except two genes previously reported to be involved in acylglucose biosynthesis.

83 ation attenuated expression of key molecules involved in adipose tissue browning and ameliorated expr

84 MBNL1, a protein involved in alternative splicing, is consistently overex

85 Residues involved in amidase activation map to a previously ident

86 ntimicrobial peptide pathway and known to be involved in antimicrobial and anti-inflammatory activiti

87 porting the notion that the macromolecule is involved in ARDS caused by SARS-CoV-2.

88 they are time-consuming, and the high costs involved in attending can exclude many potential partici

89 of messenger RNAs (mRNAs) encoding proteins involved in autophagy in colonic mucosal tissues from pa

90 led that the dataset was enriched with genes involved in auxin response and signaling; and in anatomi

91 es ratios and an elevated abundance of genes involved in bacterial growth and division.

92 vely associated with the expression of genes involved in BCAA catabolism, in conjunction with an inve

93 de range of substrates to catalyze reactions involved in bioluminescence, nonribosomal peptide biosyn

94 ene expression analysis, we identify enzymes involved in carbohydrate metabolism as transcriptional t

95 t at least three hypothalamic subsystems are involved in cardiovascular regulation in humans.

96 The mutated genes involved in cavefish vestigial eye formation have not be

97 (PPP1R12A), an important developmental gene involved in cell migration, adhesion, and morphogenesis.

98 otein CBX2 is an important epigenetic reader involved in cell proliferation and differentiation.

99 identifying several molecules and mechanisms involved in cell regulation.

100 Furthermore, we identify genes involved in cellular transport, including calcium transp

101 Furthermore, genes involved in central and energy metabolism and ribosome b

102 addition, the upregulation by heat of genes involved in chlorophyll catabolism and chloroplast prote

103 her research has examined mutations in genes involved in chromosome remodelling (for example, PBRM1,

104 HPV33 and HPV51 tended to be involved in co-infection among both unvaccinated and vac

105 w that additional and distinct processes are involved in consolidating and implementing the aftereffe

106 he heart of cellular machinery, and they are involved in converting chemical and light energy inputs

107 mity to the identified noncoding regions are involved in craniofacial embryo development in mammals.

108 baumannii on host-derived substrates and is involved in desiccation tolerance, implying that CsrA co

109 of DM promoters show an enrichment for genes involved in differentiation and development.

110 ipts coding for nuclear/cytoplasmic proteins involved in DNA packaging, replication, and protein synt

111 e) polymerase 1 (PARP-1) is a nuclear enzyme involved in DNA repair and transcription regulation, amo

112 s the transcription of the MCM6 gene that is involved in DNA replication by directly binding to speci

113 Two proteins involved in drought tolerance were also identified.

114 metalloenzyme related research, particularly involved in drug discovery targeting metalloenzymes.

115 redictors with known mechanisms of reactions involved in drug resistance (drug extrusion, drug degrad

116 nges in epigenetic modifications are closely involved in drug resistance of tumor cells.

117 hat YY1-regulated BMP6 expression in ECs was involved in EC migration.

118 ription factor that globally activates genes involved in erythroid cell development.

119 eptor responsiveness, an important mechanism involved in exertional increases in HR, in HFpEF and con

120 rongly enriched in glycosyltransferase genes involved in exopolysaccharide synthesis.

121 The biological mechanisms involved in fear transmission within families have been

122 TKFC encodes a bifunctional enzyme involved in fructose metabolism through its glyceraldehy

123 SHP2 is involved in gastrointestinal (GI) epithelium development

124 araspeckles, membraneless nuclear organelles involved in gene regulation.

125 mental results show that csdAB and csdCD are involved in Glc side-chain addition on the CWPS componen

126 a detailed analysis of the various pathways involved in glyoxylate metabolism.

127 ly, Alix is an early acting endosomal factor involved in HIV-1 budding from the cells.

128 (PI), a neuro-secretory center in the brain involved in homeostatic control, and express insulin-lik

129 ion and subcellular distribution of proteins involved in IMTG storage.

130 Our understanding of the microorganisms involved in in situ biodegradation of xenobiotics, like

131 ription factors and a nodal cytosolic kinase involved in insulin signaling.

132 , that are associated with the RB and may be involved in its function and translocation.

133 l considerations for the nano-bio interfaces involved in light-driven enzyme catalysis and points to

134 nd metabolic capacity, and to identify genes involved in lignocellulose degradation.

135 While the pathways involved in maintenance of the repressive heterochromati

136 e essential for platelet activation and also involved in megakaryocyte (MK) development and platelet

137 ltiple nuclear receptors that regulate genes involved in metabolism.

138 sulted from differential expression of genes involved in microtubules, cytoskeleton linkages, and mot

139 alizing to the mitochondria, including genes involved in mitochondrial translation.

140 ses can reveal pathophysiological mechanisms involved in more common autoimmune diseases.

141 hed new light on the interplay of components involved in multifaceted disease responses, like atheros

142 Our data suggest that parietal regions involved in multisensory and spatial memory mediate the

143 and find that this process requires factors involved in mutant mRNA decay, as in zebrafish and mouse

144 expression for a significant number of genes involved in N signalling and metabolism.

145 able cationic lipids are critical components involved in nanoparticle formulations, which are utilize

146 rgets of differentially expressed miRNAs are involved in neuroplasticity, immune function and neurore

147 tative CAM-specific genes were predominantly involved in night-time primary carboxylation reactions a

148 dent differential expression of genes (DEGs) involved in nociceptive pathways, including sensory neur

149 Here we show that beta4*nAChRs also are involved in non-nicotine-mediated responses that may pre

150 eracts with other key stereociliary proteins involved in normal hair bundle morphogenesis, such as CD

151 ing proteins (BiPs) are molecular chaperones involved in normal protein maturation and refolding malf

152 loop, a flexible element of the active site involved in nucleotide addition, can stimulate translesi

153 proteins are transcription factors that are involved in numerous physiological processes and in vari

154 -Fd can transfer electrons to a host protein involved in nutrient assimilation.

155 cts of manipulating the activity of circuits involved in opioid-mediated physiology and behaviors.

156 ogs PLDgamma2 and PLDgamma3, is specifically involved in plant immunity.

157 We conclude that SDG8 is involved in plant responses to environmental nitrogen su

158 Among them, several are involved in plant-pathogen response, which could explain

159 istep behavior, with MD regions particularly involved in processing the detail of individual steps, a

160 g 2 (SUV39H2), key histone-modifying enzymes involved in promoting reduced chromatin accessibility, a

161 pathway downstream of MMP activation that is involved in promoting the transient synaptic enlargement

162 l and persistent inhibition to brain centers involved in regulating sleep and activity.

163 novel and previously unrecognized mechanism involved in regulation of cellular iron homeostasis.

164 rs of the Ras/Raf/MAPK signaling pathway and involved in regulation of organogenesis, differentiation

165 ential component of humoral innate immunity, involved in resistance to selected pathogens and in the

166 Besides viral infections, IRF3 is also involved in resistance to some bacterial infections, in

167 on history of rubber tree, some of which are involved in rubber biosynthesis.

168 otein phosphorylation and ubiquitination are involved in SCD pathogenesis and provide further insight

169 by a spatial population code within regions involved in sensory and appetitive properties of taste.

170 found that additional important factors are involved in setting this threshold.

171 n essential component of the Smc5/6 complex, involved in sister chromatid cohesion, chromosome segreg

172 nderstand alternative translation mechanisms involved in stress tolerance and drug resistance.

173 te-directed mutagenesis to identify residues involved in substrate binding.

174 Many proteins involved in synaptic transmission are well known, and th

175 spective we present key islet miRNA families involved in T2D pathogenesis including miR-200, miR-7, m

176 A new study shows that they are also involved in taste perception in fruit flies, significant

177 The murine Zscan4 is involved in telomere maintenance and genomic stability o

178 K cell maturation, suggesting that STAT5b is involved in terminal NK cell maturation in Stat5b(-/-) m

179 However, the HA proteases involved in the activation of many viral strains remain

180 proteinases (MMPs) are extracellular enzymes involved in the degradation of extracellular matrix (ECM

181 We found gene families potentially involved in the degradation of the hydrophobic layer and

182 ts that the complex process of senescence is involved in the development of a plethora of chronic dis

183 In 2016, several clinicians involved in the diagnosis, management and care of patien

184 ng this approach, we outlined the mechanisms involved in the extirpation of native species in the pos

185 t show differences in expression of proteins involved in the focal adhesion complex but did exhibit i

186 the first evidence that LASP1 and LASP2 are involved in the formation and long-term maintenance of d

187 Poly-N-acetyl-lactosamine is involved in the immune system in many ways.

188 The Ca(2+) ATPase NCA-2 was found to be involved in the initial interaction of PAF26 with the ce

189 to what extent sensory processing areas are involved in the maintenance of sensory information in wo

190 assessed by a neurologist at each centre not involved in the management of participants' care, and mo

191 and function and, as such, may be critically involved in the pathogenesis of neurodevelopmental abnor

192 LP-1 pathway in the intestinal crypts may be involved in the pathogenesis of normalization of hypergl

193 s revealed the presence of 229 and 943 genes involved in the phenylpropanoid biosynthesis in leaf and

194 1 (IRE1alpha) branch of the UPR is directly involved in the polarization of macrophages in vitro and

195 ansport to the trans-Golgi network (TGN), is involved in the presentation of ligands from Mycobacteri

196 study, we revealed that the specific DRs are involved in the production of specific sfRNAs in both ma

197 c hypothesis that HtrA1 protease activity is involved in the progression of AMD.

198 e that addition of H to the aromatic ring is involved in the rate-limiting step.

199 sm suggests that a cobalt-hydride pathway is involved in the reaction.

200 One of the brainstem nuclei involved in the regulation of anxiety is the dorsal raph

201 l population (Cytokeratin19(-) /SOX9(+) ) is involved in the renewal of surface epithelium in injured

202 ontal lobe is an important area of the brain involved in the stress response, and higher activation w

203 gC regulates the expression of several genes involved in the sulfur assimilation and cysteine biosynt

204 Our data suggests that CSF-1 is involved in the survival and proliferation of trophoblas

205 es two of the glycosyltransferase activities involved in the synthesis of the N-glycan of the viral m

206 e, implying that CsrA controls key functions involved in the transmission of A. baumannii in hospital

207 measures and the distinct response processes involved in the two measurement types.

208 icate that 14-3-3 acts on keratin IFs and is involved in their reorganization to sites of cell adhesi

209 NA in the cytoplasm during stress and may be involved in these pathologies.

210 f both CHT or COT with PTAD and are thus not involved in these reactions.

211 flammatory cells and networked brain regions involved in threat and reward processing.

212 ulated by these genes, we find that they are involved in three main processes: neuronal transmission,

213 Whether autosis is involved in tissue injury induced under pathologically r

214 the IL-10 cytokine family, and is critically involved in tissue regeneration.

215 f a ubiquitin/proteasome degradation process involved in transcription, DNA repair, and cell division

216 lta1 population and discuss what players are involved in transducing phosphoantigen-mediated signals

217 at ERRgamma activates transcription of genes involved in virtually all aspects of postnatal developme

218 This mild and straightforward approach involves in situ formation and photoinduced activation o

219 (IL-2) through a positive feed-forward loop involving increased expression of the IL-2 receptor alph

220 -behavior relationships are flexible and may involve interactions among distant regions.

221 e was reperfusion of greater than 50% of the involved ischemic territory prior to thrombectomy, asses

222 Remarkably, controlled experiments involving isolated atmospheric ions and neat saturated h

223 udies provide evidence that a signaling axis involving key UPS components contributes to oligodendroc

224 Language is a complex construct involving linguistic as well as visual, auditory, and mo

225 This is surprising because antibiotic action involves many additional effects downstream of drug-targ

226 VC method which takes many hours to complete involving many sophisticated steps.

227 ential target for the treatment of disorders involving memory impairments.SIGNIFICANCE STATEMENT The

228 entially expressed gene clusters in pathways involving metabolism and circadian rhythm were noted in

229 pidermal keratinocytes through pathways that involve microtubule networks and the actin cytoskeleton.

230 Early structured physiotherapy involved mobilisation techniques and a graduated home ex

231 Lead optimization involved modulating potency, selectivity, and ADME prope

232 e to that of radiobiologic dose metrics that involve more complex calculations.

233 more intensive BP goal or active agent) that involved more than 500 adults with hypertension or eleva

234 hat both substrate translocation and release involve movements of the bulky transport domain through

235 abrication of architectured electrodes often involves multiple laborious steps that are not directly

236 hybrid EMT phenotypes and indicate that EMT involves multiple molecular programs.

237 The most common therapeutic needs involved new drugs (n = 149, 51.0%), cell regeneration (

238 hat homoploid hybrid speciation (HHS), which involves no change in chromosome number, is an important

239 this ongoing, double-blind, phase 1-3 trial involving nonhospitalized patients with Covid-19, we inv

240 al activity and calcium-related fluorescence involves nonlinearities and low-pass filtering, but the

241 at facilitate the visualization of processes involving nucleic acids without perturbing their natural

242 chanism of delayed OP toxicity is thought to involve off-target inhibition of serine proteases, altho

243 ferent pathways have been discerned for HATs involving OH or CH moieties.

244 an impressive development of iron complexes involving organophosphorus ligands applied in homogeneou

245 ubstantial reprogramming of tumor metabolism involving oxidative phosphorylation and fatty acid oxida

246 ized, double-blind, placebo-controlled trial involving patients with atherosclerotic cardiovascular d

247 ead to their clearance of harmful substances involve phagocytosis, endocytosis, adhesion, and signali

248 dynamics simulations on eight BAK1 mod-forms involving phosphorylation of the four activation-loop th

249 The pitfalls involve potential false-negative results due to blurring

250 ations are achieved, including variants that involve powerful dearomatizations and medium ring format

251 pioid-induced excitatory synaptic plasticity involves presynaptic and postsynaptic elements as well a

252 tify complex system process evaluations that involve qualitative methods by searching electronic data

253 ment-binding protein 3-like 1 (CREB3L1) also involves RAT.

254 Completion of coformycin biosynthesis involves reduction and dephosphorylation of the CofB pro

255 ity of pollen and spore walls, the processes involved remained obscure until the structures observed

256 of the first whole-ecosystem experiments to involve replicated metagenomic assessment.

257 e first conformational change in our dataset involves rotation of the inner-gate backbone along resid

258 These Recommendations involve rules of conduct, procedures, and safety measure

259 n of higher-order structures was complex and involved self-templating.

260 action proceeded through a cascade mechanism involving several intermediates identified by mass spect

261 vasculitides (AAVs) are a group of disorders involving severe, systemic, small-vessel vasculitis and

262 The AC insertion has thus been concluded to involve solely the AC acyl chain.

263 th nonspecific symptoms, but their detection involves specific therapeutic strategies.

264 tes GI function and disease progression that involve stem/progenitor cells and inflammation in a tiss

265 ans is still unknown due to the difficulties involved studying the human brain via electron microscop

266 Pathways from C1 -> H1 involve the bimolecular reaction of EHP with different a

267 otein quantitation by mass spectrometry (MS) involve the digestion of target protein and employ isoto

268 Parkinson's disease (PD) pathogenesis may involve the epigenetic control of enhancers that modify

269 Thanatotranscriptome studies involve the examination of mRNA transcript abundance and

270 ost strategies to alter seed oil composition involve the overexpression of lipid biosynthetic enzymes

271 s to herbivores promote resistance and often involve the perception of specific herbivore-associated

272 A third route involves the addition of the c(8)-ring module to the com

273 e electronic Seebeck response in a conductor involves the energy-dependent mean free path of the char

274 Voluntary movement initiation involves the modulations of large groups of neurons in t

275 This process called V(D)J recombination that involves the RAG recombinase binding and cutting recombi

276 Molecular tagging involves the selective modification of particular functi

277 ease model of a common form of heart disease involving the aortic valve (AV).

278 ed therapies through a mechanosignaling loop involving the autocrine remodeling of a drug-protective

279 A simple model involving the biocatalytic reaction network coupled with

280 rare, benign and local inflammatory disease involving the epiploic appendices.

281 e of the simplest cyclopropanation reactions involving the intramolecular coupling of two C-H bonds o

282 Balanced rearrangements involving the KMT2A gene, located at 11q23, are among th

283 With non-human primates, in an online task involving the one-dimensional decoding of the movement o

284 Despite involving the same causative allergens, allergy immunoth

285 he open metal sites of MOFs for applications involving the strong and/or selective binding of O(2).

286 s suggest the possibility of a feedback loop involving these two genes, with the CTNNB1 S45F mutation

287 p53 mutants reveal a cryptic allosteric site involving three arsenic-coordinating cysteines within th

288 in addition to the amyloidosis type, organs involved, treatment given, and survival.

289 In contrast, the MA involved tri-enzyme extraction including human plasma as

290 Mouse models of DS, involving trisomy of all or part of human chromosome 21

291 Molecular regulation, on the other hand, involves tuning an optimal local protein environment for

292 re, agonist-induced signaling in this system involves two distinct receptor-G protein complexes, a co

293 We reveal a gating mechanism that involves two ion-conducting pathways.

294 The methodology developed involves two sequential acid treatments followed by step

295 low pH and facilitating a late step in entry involving uncoating and delivery of the RNA genome to th

296 te-limiting step in mRNA cleavage frequently involves unmasking of target sites by translating riboso

297 ify artery tone and tissue perfusion but the involved vascular-sensing mechanisms and disease consequ

298 Hall effect (AHE) induced by the transition involving Weyl points and nodal rings.

299 ome-wide significant associations near genes involved with global regulation of gene expression (SATB

300 The proportion of involved zones was lower in outpatients compared with ot