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1 g upon the position of the aryl ring that is iodinated.
2 pharmacological characterization of a novel iodinated 1,4-dihydropyridine KATP channel opener, [125I
3 l)(8),IAmp(9)]-SRIF-Thr-NH(2) (25) was radio-iodinated ((125)I-25) and specifically labeled sst(1)-ex
6 nd the selective 5-HT2A receptor ligand 123I iodinated 4-amino-N-[1-[3-(4-fluorophenoxy)propyl]-4-met
9 aled PhII(OH).NH(3) to be the most plausible iodinating active species as a reactive "I(+)" synthon.
11 eing protonated to afford protiotriazole, an iodinating agent presumably intercepts the copper(I) tri
12 de and terminal alkyne in the presence of an iodinating agent, with 5-protio-1,2,3-triazole (protiotr
14 ers hypoiodous acid (HOI) as the predominant iodinating agent; nevertheless, HOI (pK(HOI) = 10.4) cou
15 ared to that of the wild type as measured by iodinated alpha-bungarotoxin binding ([(125)I]-alpha-BgT
16 s study reports the identification of a lead iodinated analog 5 of the clinical PARP-1 inhibitor olap
19 aration and characterization of novel potent iodinated analogs of the NSAIDs indomethacin and suprofe
23 h several other unique proteins that surface iodinate and migrate at approximately 15, 20, and 25 kDa
25 diatom exudes a diverse mixture of volatile iodinated and brominated metabolites including the natur
26 -phase liver imaging protocol via the use of iodinated and gadolinated contrast agents on four health
27 However, safety concerns limit the use of iodinated and gadolinium (Gd)-based CT and MRI contrast
29 n an approach in which TAM is site-selective iodinated and subsequently C-C cross-coupled to various
32 promote the formation of toxic brominated-, iodinated-, and nitrogen disinfection byproducts during
35 is investigation was to develop a method for iodinating annexin V that would be suitable for the in v
37 ently described the in vivo properties of an iodinated anti-p185HER2 engineered antibody fragment [mi
38 ntibodies are retained longer in tumors than iodinated antibodies, leading to their increased use for
41 Receptor function was assessed by uptake of iodinated asialo-orosomucoid, immunoglobulin (Ig) A1, an
43 The radiodiagnostic hypoxic markers beta-D-iodinated azomycin galactopyranoside (IAZGP) and [99mTc]
44 rbazone) and approach those of beta-D-(125)I-iodinated azomycin galactopyranoside, the optimal hypoxi
45 were prepared using Pd-mediated coupling of iodinated base derivatives with a deoxyribose precursor.
49 values were not significantly different from iodinated bitistatin, but uptakes were higher than other
53 e for many compounds, including highly toxic iodinated, brominated, and nitrogen-containing DBPs.
54 ndoplasmic reticulum subfractions with radio-iodinated calreticulin showed specific associations with
55 rmal in respect of superoxide production and iodinating capacity, are unable to resist staphylococcal
60 re used to study binding and transcytosis of iodinated Clostridium botulinum neurotoxin serotypes A,
61 s administration of high-dose low-osmolarity iodinated CM appears safe in patients without renal dysf
64 F that are currently used in the clinic, the iodinated compounds described herein are applicable in p
65 g, and biological profile of a new series of iodinated compounds for potential translation to the cor
66 risk of contrast nephropathy associated with iodinated computed tomography contrast, alternate contra
67 1 receptor, preserves renal blood flow after iodinated contrast administration and has shown promise
68 fficient large-scale synthesis of a cationic iodinated contrast agent (CA4+) is described for imaging
69 and 0% to 6.25% and 93.75% for both), and an iodinated contrast agent and saline (7.6-1.6 mg per mill
71 anced abdominal scan, iobitridol, a nonionic iodinated contrast agent containing 350 mg of iodine per
72 was assigned to a corresponding time-varying iodinated contrast agent to create the contrast material
74 mages acquired after administration of a 35% iodinated contrast agent, there was a statistically sign
80 is and evaluation of a new class of cationic iodinated contrast agents for the imaging of cartilage u
83 ts in imaging and interventional techniques, iodinated contrast continues to pose a risk of contrast-
86 MRI/A avoids the risks of arterial puncture, iodinated contrast load, and radiation exposure, while p
88 veset trisodium) diluted in either saline or iodinated contrast material (50% and full-strength iohex
89 y function who underwent CT with intravenous iodinated contrast material (ICM) had a similar frequenc
93 (n = 21) ingested 10-mL aliquots of nonionic iodinated contrast material (iopromide) with a concentra
94 irment, substantial reductions in the use of iodinated contrast material can be achieved by using low
95 ompartments of a CT phantom were filled with iodinated contrast material diluted to attain attenuatio
99 was used for injection of up to 1,000 mL of iodinated contrast material into one pelvic extraperiton
101 suggests the need to consider the effect of iodinated contrast material on the organ doses to patien
102 le in patients with a history of reaction to iodinated contrast material or renal insufficiency.
103 rattenuation classified at dual-energy CT as iodinated contrast material staining (n = 20, 71%), hemo
104 al-energy CT can help differentiate ICH from iodinated contrast material staining with high sensitivi
105 arlier, and nongated CT images obtained with iodinated contrast material to evaluate trauma 8 years p
106 viously undergone nephrectomy, 100 mL of 60% iodinated contrast material was injected at 3 mL/sec (gr
107 traarterial or intravenous administration of iodinated contrast material were evaluated by using dual
108 NGAL depicted CIN in patients who received iodinated contrast material within 8 hours of contrast m
110 canning duration, scanning coverage, dose of iodinated contrast material, and mean aortoiliac attenua
119 ter placement, cavography was performed with iodinated contrast material; these images were compared
121 a well-documented side effect of the use of iodinated contrast media (ICM) administered intravenousl
122 f suspect screening for the detection of six iodinated contrast media (ICM) and their phototransforma
125 n critically ill patients commonly depend on iodinated contrast media and consequently pose the risk
126 nd coronary/vascular interventions depend on iodinated contrast media and consequently pose the risk
129 efined criteria, suggesting that intravenous iodinated contrast media may not be the causative agent
130 ad no known allergies, and prior exposure to iodinated contrast media on two occasions (2 months and
131 celerated hyperthyroidism after injection of iodinated contrast media to evaluate a left hemipelvis m
134 ous transluminal balloon angioplasty with an iodinated contrast medium (20 mL Iopamiro; Bracco, Milan
135 owing intravenous injection of 174-185 mL of iodinated contrast medium (300 mg iodine per milliliter)
138 or 69,657 intravenous injections of nonionic iodinated contrast medium for computed tomographic exami
139 xic effect of monomeric nonionic low-osmolar iodinated contrast medium in ICU patients with multiple
140 ere included (20% more than once), before an iodinated contrast medium infusion (contrast inclusions,
141 or before an intrahospital transfer without iodinated contrast medium infusion (control inclusions,
143 ontrol inclusions, matched on propensity for iodinated contrast medium infusion, the incidence of acu
148 ration Spontaneous Reporting System, data on iodinated contrast medium-related deaths after LOCM beca
153 patients with virtual colonoscopy using oral iodinated contrast preceding conventional colonoscopy.
155 (2.5%) patients, it was necessary to perform iodinated contrast-enhanced cavography before filter dep
156 parison of cavograms obtained with CO(2) and iodinated contrast-enhanced material showed the caval si
160 e unfavorable properties displayed for these iodinated cyclized amide derivatives for in vivo biodist
161 hocytes, and that incubation of T cells with iodinated CyPA, followed by chemical cross-linking, resu
165 high affinity, KD approximately 3 nM, for an iodinated derivative of glyburide, an anti-diabetic sulf
167 effective at inhibiting the binding of radio-iodinated diferric glycosylated hTF from a commercial so
168 after 24 h) was transformed to known organic iodinated disinfection byproducts (DBPs) of low molecula
169 well as enhanced formation of brominated and iodinated disinfection byproducts (DBPs) when treated.
170 mitigate the formation of potentially toxic iodinated disinfection byproducts (I-DBPs) while control
171 s have elucidated the agent(s) that generate iodinated disinfection byproducts during drinking water
173 py of viable V79 cells demonstrated that the iodinated dye stained the nuclei with avidity similar to
177 compared tissue uptake and metabolism of two iodinated fatty acid analogs BMIPP and 15-(p-iodophenyl)
178 KD (620 nM) at the cloned NTR-1, NT27-I (the iodinated form of NT27) exerted a potent hypothermic eff
181 ided for the analysis of the HAAs (including iodinated HAAs) by diazomethane derivatization and analy
182 rent chemical classes, including unregulated iodinated haloacetic acids (HAAs) and trihalomethanes (T
189 ldiynes 1 with one equivalent of iodine gave iodinated indeno[1,2-c]chromenes 3 in good chemical yiel
193 formation may occur via a transiently stable iodinated intermediate rather than by direct single-elec
194 roalkynyl- analogues, prepared from a common iodinated intermediate via Sonogashira coupling reaction
196 percutaneous intervention rely on the use of iodinated intravascular contrast for vessel and chamber
197 rauma, or both were imaged with simultaneous iodinated intravenous and bismuth subsalicylate enteric
198 n solution phantoms and in a rabbit in which iodinated intravenous and bismuth subsalicylate oral con
199 e were 57 adverse events related to nonionic iodinated intravenous contrast material in 12,494 consec
200 tero exposure to water-soluble, low-osmolar, iodinated intravenous products, such as iohexol, is unli
201 1-42) and showed that, after i.v. injection, iodinated JV-1-42 (131I-JV-1-42) enters the brain intact
207 , foam cell content, and aortic pool size of iodinated LDL particles of aortic atherosclerotic plaque
210 synthesis and properties of a high-affinity iodinated ligand that selectively binds the alpha/delta
217 odal approach using a single fluorinated and iodinated melanin-targeting structure and offering both
221 dose, AHF was measured by dilution of radio-iodinated monkey albumin perfused through the anterior c
222 tarting materials for the synthesis of three iodinated monomeric moieties (a modified lactide, morpho
225 nd after intravenous bolus administration of iodinated non ionic contrast agent; CT images demonstrat
232 mb ischemia, for which the administration of iodinated or gadolinium-based contrast agents is contrai
233 mmatory drugs (10.2%), acetaminophen (3.9%), iodinated or magnetic resonance imaging contrast media (
235 ng, opacification, and taste preference with iodinated oral contrast medium (ICM) in standard (sICM)
236 Conclusion A 25%-reduced concentration of iodinated oral contrast medium resulted in acceptable bo
237 halogenated organic compounds, particularly iodinated organic molecules, are absent from inland natu
241 e an antisense imaging agent comprised of an iodinated peptide nucleic acid (PNA) conjugated to a mon
242 irmed by experiments in which the binding of iodinated peptide was blocked by unlabeled Qdm and not b
243 tatin retains the functional activity of the iodinated peptide, has higher DVT and PE uptakes than ot
245 ne-containing polymers, in comparison to non-iodinated poly(lactic acid) (PLA), validated their funct
247 yl-iodo monomers, which were used to prepare iodinated polyesters using a pre-functionalization appro
254 d hormone/PTHrP receptor-mediated binding of iodinated PTHrP or steady-state receptor message by Nort
255 ding characteristics of the Mpl receptor, we iodinated purified 70-kD recombinant human Tpo using the
257 tibodies were used to inhibit the binding of iodinated purified fimbriae as well as the binding of P.
259 the interaction-binding between a series of iodinated quinazolinone derivatives and human placental
260 ptor autoradiographic technique utilizing an iodinated radioligand [(125)I]ZM 241385, which has great
262 key step as a highly selective and efficient iodinating reagent for a short and convenient synthesis
263 sue sections by in situ ligand binding using iodinated recombinant human inhibin A and 125I-labeled r
265 ine/kg body weight), tumors showed a heavily iodinated rim surrounding the tumor having an average up
266 romide and its metabolites revealed that the iodinated ring remains intact and that minor transformat
270 A from the cell cultures was cleaving scHGF, iodinated scHGF was added to intact cells in the presenc
273 , and 15 mm in diameter) filled with various iodinated solutions to simulate hypervascular liver lesi
274 ne to simulate the unenhanced state and with iodinated solutions to simulate the three levels of rena
278 cycloheximide markedly decreased binding of iodinated systemin to the cells, indicating that the bin
279 to small molecules and proteins and generate iodinated tetrazines for bioorthogonal chemistry has bee
280 osine into beef thyroid slices, isolated and iodinated the [14C]thyroglobulin (Tg I), separated its N
281 nnyl)benzoate (Boc-SGMTB, 3) was first radio-iodinated to [*I]Boc-SGMIB, a derivative of [*I]SGMIB wi
283 thway, multiple tyrosine residues can become iodinated to form mono-iodotyrosine (MIT) and/or di-iodo
284 llicular compartment, where thyroglobulin is iodinated to form the protein precursor to T(4) and T(3)
286 s from purified hydrogenosomes obtained from iodinated trichomonads confirmed the specific surface la
287 ed HAN and regulated THM formation; however, iodinated trihalomethane formation was observed at lower
288 peciation toward formation of brominated and iodinated trihalomethanes (THMs) and brominated haloacet
290 olumn samples, unilaterally perfused with an iodinated vascular contrast agent, and three extracted f
294 sistance to biological wastewater treatment, iodinated X-ray contrast media (ICM) have been detected
296 cals (antibiotics, antimycotics, antivirals, iodinated X-ray contrast media, antiinflamatory, cytosta
297 sport and biochemical transformations of the iodinated X-ray contrast medium (ICM) iomeprol were stud
299 This result was identical for both surface-iodinated YT cells and immunoprecipitates that were prob
300 ds based on Sonogashira cross-coupling of an iodinated zinc phthalocyanine with acetylenic bombesin o