ライフサイエンスコーパス: ion

1 r containing proteins (homo and hetero metal ions).

2 ong magnetic axiality on the central Dy(III) ion.

3 f unsymmetrical phenonium ions with chloride ions.

4 hosphate, sulfate, chloride, and carboxylate ions.

5 de anion (TFSI(-) ) to coordinate with Li(+) ions.

6 he number of incorrectly annotated principal ions.

7 one-pot' coordination of soft and hard metal ions.

8 anging the potassium surface ions for copper ions.

9 ecific transport of other metabolites and/or ions.

10 of internal Na(+) and Cl(-) as well as other ions.

11 ganize interfacial water similarly to halide ions.

12 stabilization of this domain by bound metal ions.

13 odes in the presence of Mg(2+) versus Mn(2+) ions.

14 trahigh proton (H(+)) selectivity over other ions.

15 annelrhodopsins, it is impermeable to Ca(2+) ions.

16 roduct ions to their corresponding precursor ions.

17 icantly and beneficially alters sheath based ion acceleration and creates two distinct stages in the

18 tic simulations of laser driven sheath-based ion acceleration with a kilotesla-level applied magnetic

19 functional class, bioinorganic class, metal ion and metal-containing cofactor, which will serve as a

20 ation produced a greater variety of fragment ions and complementary ion pairs leading to more complet

21 s a spontaneous array of differently charged ions and is associated with electronic phenomena such as

22 d experiments involving isolated atmospheric ions and neat saturated hydrocarbons in vacuum yielded a

23 nd module orchestrates the transport of both ions and proteins to the shell secretion site, which are

24 The pH, the ZnSO(4)/PS ratio, and ions and quenchers, were investigated.

25 widely applicable to all families of porous ions and represents a new and powerful method for the sy

26 scan (2D MS/MS scan) in which all precursor ions and their subsequent product ions are both identifi

27 uranium polyatomic interferences ((235)UH(+) ions) and an accurate determination of low (236)U/(238)U

28 nds, pai-interactions, coordination to metal ions, and few halogen bonds in chloropyrazines.

29 precursor ions and their subsequent product ions are both identified and correlated.

30 In this work, nitrenium ions are explored as catalysts in five organic transform

31 ciation and transport behaviors of phosphate ions are highly influenced by electrolyte pH, and it use

32 t, Au, Eu) in these applications by abundant ions are outlined with selected examples.

33 transport process, there is a state in which ions are stably trapped within the permeation pathway of

34 localization of actin filaments and divalent ions are suppressed, and cells rely on linker proteins t

35 at are only active in the presence of copper ions, are effective bactericidal agents against MRSA.

36 ), layered molecular crystals(3) and trapped-ion arrays(4) are a few examples.

37 ols employing thiophenol-stabilized iodonium ion as a catalyst.

38 rgo rearrangement, sometimes forming bridged ions, as well as their ability in many cases of spreadin

39 he thermodynamics of a transition metal (TM) ion assembly be it in proteins or in coordination comple

40 y, our simulations show that the third metal ion assists the departure, through the mobile arch, of t

41 catalyzed by a trisaminocyclopropenium (TAC) ion at mild electrochemical potential with visible light

42 eral ion currents lead to an accumulation of ions at the drain contact, which significantly alters th

43 Commercial lithium-ion batteries (LIBs), limited by their insufficient reve

44 Solid-state Li-ion batteries (SSLIBs) have recently attracted substanti

45 Sodium-ion batteries have captured widespread attention for gri

46 next-generation high-energy, cobalt-free Li-ion batteries.

47 the structural stability of Si-based lithium-ion batteries.

48 Superior performance is achieved as a Li-ion battery cathode with a high reversible capacity (387

49 e detectors can be integrated into a focused ion beam (FIB) system which, assembled with scanning ele

50 Focused ion-beam scanning electron microscopy of infected cells

51 two amino acids were detected using focused-ion-beam-modified ultrashort cantilevers.

52 gineering such a selective multivalent metal ion binding site into target macromolecules for structur

53 no acids) affording high-affinity lanthanide ion binding, and X-ray fluorescence microscopy (XFM).

54 of delaying Abeta aggregation via weak metal-ion binding, quantitatively linking the contributions of

55 The FRET efficiency is modulated upon Ca(2+) ion binding.

56 they are potential competitors for a copper ion bound in a copper drug.

57 Such ion-by-ion diffusion and attachment may occur from the s

58 alone can never fill space completely, thus ion-by-ion filling must be invoked to fill interstitial

59 r-infrared (NIR) genetically encoded calcium ion (Ca2+) indicators (GECIs) can provide advantages ove

60 When operated at constant trapping voltage, ions can be activated at their secular frequencies and a

61 +)X(-) with 11 different Lewis bases (halide ions, carboxylates, p-nitrophenolate, amines, and tris(p

62 ion of Remazol black B dye by employing iron ions catalyst based gas diffusion cathodes, (GDCs).

63 ascade among excited spin states of the iron ion, causing the ferric heme to undergo doming, which we

64 to the molecular-level understanding of how ions change the structure and dynamics of the EDL.

65 tigated the relationship between bioelectric ion channel activity and calcium, finding that cell hype

66 ss our current understanding of ligand-gated ion channel and G protein-coupled receptor complexes and

67 , including myelin, axonal cytoskeleton, and ion channel antigens, in individual patients.

68 hondrial calcium uniporter is a Ca(2+)-gated ion channel complex that controls mitochondrial Ca(2+) e

69 dissecting the phospholipid requirements of ion channel complexes.

70 PCR and western blotting were used to assess ion channel expression.

71 SthK, a cyclic nucleotide-modulated ion channel from Spirochaeta thermophila, activates slow

72 fect of the four stillbirth mutants on TRPM7 ion channel function in heterologous cells.

73 A native calcium ion channel has been identified in bacteria for the firs

74 TrkH is a bacterial ion channel implicated in K(+) uptake and pH regulation.

75 f-function mutations in the mechanosensitive ion channel PIEZO1 were shown to ameliorate Plasmodium p

76 The transient receptor potential ion channel TRPA1 is expressed by primary afferent nerve

77 e the sequence homology between acid-sensing ion channels (ASICs) and epithelial sodium channel (ENaC

78 are anion-permeable pentameric ligand-gated ion channels (pLGICs).

79 d optically were confirmed to be mediated by ion channels and experimental data suggests an insignifi

80 ting receptor proteins, such as ligand-gated ion channels and G protein-coupled receptors, has direct

81 s essential to determine their complement of ion channels and to understand the function of biologica

82 atment with antagonists of both acid-sensing ion channels and transient receptor potential vanilloid

83 sient receptor potential vanilloid 4 (TRPV4) ion channels are a major Ca(2+) influx pathway in endoth

84 Mechanosensitive ion channels are crucial for normal cell function and fa

85 icacy is reminiscent of multisubunit protein ion channels assembled with incorrect monomer stoichiome

86 strate that clusters of strongly cooperative ion channels can plausibly form bistable conductances.

87 review, we focus on PIP(2) as a regulator of ion channels in smooth muscle cells and endothelial cell

88 Our goal was to identify ion channels involved in mechanically induced myotonia a

89 in their selectivity for human voltage-gated ion channels involved in the ventricular action potentia

90 At least 5 ion channels show a circadian expression pattern in the

91 NMDA receptors (NMDARs) are glutamate-gated ion channels that mediate fast excitatory synaptic trans

92 -HT(3) receptors are pentameric ligand-gated ion channels that regulate synaptic activity in the cent

93 nto the loops or termini of different GPCRs, ion channels, receptors and transporters without disrupt

94 or-neighbor activation of energy-dissipating ion channels, while hydrogen peroxide distributes oxidat

95 igomerisation of the protein into functional ion channels.

96 y of synaptic neurotransmitter receptors and ion channels.

97 the influx of extracellular calcium through ion channels.

98 e many advances in the study of acid-sensing ion channels.

99 Therefore, an increased ion charge results in a dramatic decrease in the sensor

100 tgun tandem mass spectrometry with gas-phase ion chemistry to achieve both differentiation and quanti

101 Extracted ion chromatograms of isomeric glycoforms enabled quantit

102 nescent method were consistent with those by ion chromatographic strategy.

103 Ion-chromatography coupled to high resolution mass spect

104 nutrient loading and perturbations to major ion composition have resulted from human activities and

105 Parallel (multichip) screening of ferric ion concentration gradients (0-40 mM) and temperature (2

106 The impact of the ammonium ion concentration on 10-50 mum aerosol droplet pH was qu

107 ges with the pH, temperature, and the ferric ion concentration, consistent with previous bulk-scale s

108 gies by scanning electron microscopy and the ion-concentration analysis by inductively-coupled plasma

109 th, it experiences changes in morphology and ion concentrations.

110 Scanning ion conductance microscopy (SICM) has emerged as a versa

111 p-n junction due to self-polarization in the ion-conducting Bi(46)V(8)O(89) constituent.

112 rom the known channelrhodopsins and a unique ion-conducting pathway.

113 reveal a gating mechanism that involves two ion-conducting pathways.

114 o not inhibit the phospholipid-scrambling or ion conduction activities of the dual-functional TMEM16F

115 evelop functional MOF channels for selective ion conduction and efficient ion separation.

116 rved in N(2), while CCS for the most compact ion conformations sampled on the 6560 are systematically

117 1500 (+/-8%) water molecules per Ar(1800)(+) ion, consistent with our results from molecular dynamics

118 samples up to 100% of the peptide precursor ion current in m/z and mobility windows.

119 uld be traced to the different expression of ion currents in the two.

120 model is presented, which shows that lateral ion currents lead to an accumulation of ions at the drai

121 Fourier transform ion cyclotron resonance mass spectrometry (FTICR MS) pro

122 y binding sites for substrate K(+) and Cl(-) ions, demonstrate the importance of key coordinating res

123 With severe ion depletion gradients in the electrolyte during chargi

124 Such ion-by-ion diffusion and attachment may occur from the supersat

125 surface, increasing local barriers for Li(+) ion diffusion.

126 mining step rather than electron transfer or ion diffusion.

127 the amorphous limit due to intensive mobile ion disorder and reduced vibrational entropy.

128 rovide the unique opportunity to investigate ion dissociation from infinite dilution in the solvent t

129 re significantly redshifted relative to when ions do not occupy adjacent sites.

130 assessed the internal heating experienced by ions during trapped ion mobility spectrometry (TIMS) exp

131 n substituting precious and rare-Earth metal ions (e.g. Ru, Ir, Pt, Au, Eu) in these applications by

132 bility profile, intrinsic solubility, common-ion effect, pK(a), pH(max), and K(sp) values of three mo

133 es occurs at <+1 V in the presence of mobile ions, enabled by ionic screening of the carbon electrode

134 ticipates in the solvation sheath of lithium ions enabling more bis(trifluoromethanesulfonyl)imide an

135 eding thirty milliseconds for cavity-coupled ions, even at temperatures greater than one kelvin.

136 xplore alternate electrode materials, use of ion exchange membranes, and development of other sensor

137 ater molecules between the layers allows for ion exchange with 3d and 5f metal cations.

138 Size-exclusion and ion-exchange chromatography were used to fractionate var

139 An ion-exchange-HPLC (with anion and cation exchange column

140 asis of cell signaling and apoptosis-related ions [fatty acids (341.2100 and 382.3736 m/z) and glycer

141 can never fill space completely, thus ion-by-ion filling must be invoked to fill interstitial pores.

142 chemical ionization method known as selected ion flow tube-mass spectrometry (SIFT-MS).

143 tical calcium imaging, which records calcium ion flux indicating occurrence of an action potential, t

144 sity required to produce the observed pickup ion fluxes is similar to typical exospheric densities fo

145 21-plex DiLeu tags generate strong reporter ions following HCD fragmentation of labeled peptides acq

146 Results indicated that PLA2 required calcium ion for both the hydrolyzing activity and the antioxidan

147 be tuned by exchanging the potassium surface ions for copper ions.

148 platform based on single coherent rare-earth ions for the future quantum internet.

149 la: see text], wherein the overall energy in ions [Formula: see text] increases by an order of magnit

150 glycans was achieved utilizing TMT reporter ions from HCD MS3 spectra.

151 Pt and RE metal ions from the most common hydrated metal salts are first

152 prove a near-surface desolvation of lithium ions from their water solvation shell as compared with o

153 Ion packets introduced from gates, ion funnel traps, and other conventional ion injection m

154 glass transfer capillary followed by a dual ion funnel.

155 Consequently, ions generate transient electrical currents first discov

156 Evidence of this third ion has been observed in several nucleic-acid-processing

157 Similarly, a/x and c/z ions have also undergone H/D scrambling due to UV-induce

158 These ions have optical and spin transitions that are first-or

159 he evolution of K at high E/N causing strong ion heating.

160 es that might disrupt neuronal membranes and ion homeostasis.

161 ic techniques to prepare a trapped molecular ion in a single quantum state, drive terahertz rotationa

162 ometer and begins with selection of a parent ion in the MS scan, followed by tandem mass spectrometry

163 based catalyst design, the trafficking of TM ions in biological systems, and drug design in metallopr

164 unction of the constituent Mn(2+) and Ca(2+) ions in genetically engineered membranes of the cyanobac

165 tric forces cause the movement of pore water ions in opposite directions, leading to charge interacti

166 Trapped molecular ions in pure rovibronic states are desirable in experime

167 s with energies of mega-electron volts, cold ions in the inner wall surface implode towards the centr

168 ydroxyl ligands and charge balancing calcium ions in the interlayer space.

169 ranium, as the hexavalent uranyl (UO(2)(2+)) ion, increases significantly with increasing temperature

170 air Search identifies O-glycopeptides via an ion-indexed open modification search and localizes O-gly

171 We find that the metal-ion-induced folding can proceed with stereoinduction: in

172 es, ion funnel traps, and other conventional ion injection mechanisms produce ion pulse widths typica

173 onsists of a 3D Zn-Sb framework hosting K(+) ions inside polyhedral cages, some of which are reminisc

174 Ion intercalation electrodes are being investigated for

175 These sodiated ions interfere with protonated ions of the species of th

176 the two bent bonds of bicyclic oxocarbenium ion intermediates in an antiperiplanar fashion.

177 phize crystalline silicon by means of helium-ion irradiation, enabling the formation of a completely

178 ion of SERCA, and binding of a single Ca(2+) ion is sufficient to shift the protein population toward

179 measures of exact masses of formed fragment ions, it could be concluded that some of these unknown c

180 e electrode materials, especially for sodium-ion layered oxides, motivating the exploration of high c

181 The inclusion of divalent ions leads to a reversal of the binding affinity.

182 ial loss of formamidinium [CH(NH(2))(2) (+)] ions, leaving behind a partially unoccupied perovskite l

183 approach, called UVHis-PAGE, that uses metal ion-loaded and fluorescently labeled chelator heads to d

184 The analytical utility of chimeric ion loading is demonstrated for top-down proteomics, but

185 metry separations in structures for lossless ion manipulations coupled to mass spectrometry (SLIM IMS

186 (IMS) combined with time-of-flight secondary ion mass spectrometry (TOF-SIMS) imaging.

187 n the first systematic study using secondary ion mass spectrometry with MeV ions (MeV-SIMS) for analy

188 The differences as observed by secondary-ion mass spectrometry, differential scanning calorimetry

189 so far for catalysts based on a single metal ion mechanism.

190 ing secondary ion mass spectrometry with MeV ions (MeV-SIMS) for analysis of synthetic organic pigmen

191 +) and produces a drastic reduction of Cu(+) ion migration by nearly two orders of magnitude.

192 Typically, ion migration for crystal deformation or connection with

193 (3D) polycrystalline perovskites suffer from ion migration, which causes overshoot of luminance over

194 inescence nanoparticles (D-PLNPs) with metal ions (MIs) and for the first time proposed an MIs-trigge

195 n both electrodes individually, including Li-ion mobility and its changes with temperature.

196 This cell was installed between the ion mobility and time-of-flight regions of the instrumen

197 s paddlewheel dynamics contribute to Lithium-ion mobility at room temperature.

198 lecular weight and ion mobility in a trapped ion mobility device (timsTOF Pro) to devise a scan mode

199 e of the correlation of molecular weight and ion mobility in a trapped ion mobility device (timsTOF P

200 intact HS saccharides are dissociated in an ion mobility mass spectrometer and collision cross secti

201 iology, collision cross sections (CCSs) from ion mobility mass spectrometry (IM-MS) measurements are

202 Here, we develop a "Shotgun" Ion Mobility Mass Spectrometry Sequencing (SIMMS(2)) met

203 geted peptide quantification using a trapped ion mobility quadrupole time-of-flight mass spectrometer

204 Ion mobility spectra of citric acid (CA) are complex, an

205 ation (vt-ESI) technique in combination with ion mobility spectrometry (IMS) and mass spectrometry (M

206 ically around a few microseconds or less for ion mobility spectrometry (IMS)-based separations on the

207 l heating experienced by ions during trapped ion mobility spectrometry (TIMS) experiments.

208 Trapped ion mobility spectrometry (TIMS) is presented as a new a

209 ein, we report on the use of high-resolution ion mobility spectrometry separations in structures for

210 Ion mobility-mass spectrometry (IM-MS) has become a powe

211 where mass-selected structural studies using ion-mobility spectrometry mass spectrometry (IMS-MS) cou

212 are observed and identified in the positive ion mode and the results are in agreement with reported

213 s were evaporated and ionized using negative ion mode electrospray ionization, transferred into a lin

214 133/58 lipid features in positive-/negative-ion mode from mouse cerebellum tissue.

215 oppositely oriented relative to thiocyanate ions near neutral surface sites.

216 When ions occupy adjacent sites in the selectivity filter, th

217 eal QD doping when incorporation of magnetic ions occurs solely via addition of Mn-Se units without u

218 first isotopic peak overlaps with ammoniated ions of a species with one additional CH(2) and four dou

219 hese sodiated ions interfere with protonated ions of the species of the same lipid class with two add

220 profoundly from binding of multiply charged ions, often leading to overall compaction of the protein

221 Sputter yield of a 20 keV Ar(1800)(+) ion on ice has been determined as 1500 (+/-8%) water mol

222 ing of QD excitons with proximate molecules, ions, or other QDs.

223 Ion packets introduced from gates, ion funnel traps, and

224 far-reaching consequences in stereoselective ion pair catalysis.

225 The ensuing charge separated radical ion paired complex is spectroscopically characterized, w

226 odecane to yield overall neutral, internally ion-paired supramolecular polymers.

227 ace sites and those participating in contact ion pairing adopt similar orientations and are oppositel

228 The synergistic roles of the three ion pairs formed by the V(O) defect, including Cu(1+) -T

229 r variety of fragment ions and complementary ion pairs leading to more complete functional group char

230 es pave the way for the design of functional ion pairs that have the potential to participate in tand

231 ansporters carrying HCO3- , CO3= , or NaCO3- ion pairs.

232 istry that only occurs among closely contact ion-pairs, which constitutes the rationale behind the "w

233 leaf entry pathways for inorganic phosphate ion (Pi) uptake remain unknown, and it is unclear whethe

234 g due to UV-induced heating of the precursor ion population.

235 /D scrambling in the nonfragmented precursor ion population.

236 -) anions, which in turn modulates the Li(+) ion potential energy surface, increasing local barriers

237 Structure- and CE-specific oxonium ions provide sufficient information for the resolution o

238 onventional ion injection mechanisms produce ion pulse widths typically around a few microseconds or

239 Mutations of the ion pump alpha2-Na/K ATPase cause familial hemiplegic mi

240 odes of action (i.e. CdCl(2) toxicity versus ion pump inhibition by ouabain), a significant advance a

241 mposition of the RE-metal node being RE(iii)-ions, RE(iii)-chains, or RE(iii)-clusters.

242 have supported the idea that this monovalent ion reduces agonist binding by stabilizing the receptor

243 es the capability to design high-performance ion-regulating devices and promotes the utilization of s

244 high intensities, while at high flow rates, ions related to higher charge states of proteins dominat

245 ) systems because they can achieve selective ion removal and low energy deionization.

246 5) by plotting the measured ratios of the MS ion responses against the known spiked-in ratios (CVs <

247 ms the additive CHARMM36 force field in both ion retention and maintenance of the GQ folds.

248 lity constituents including nutrients, major ions, sediment, and specific conductance were analyzed o

249 Each ion-selective electrode functions in an equilibrium mode

250 ochemical cell composed of several identical ion-selective electrodes immersed into separate sample s

251 tuning of ion-transfer (IT) processes across ion-selective membranes (ISMs) with thicknesses in the n

252 lar loops as important structural motifs for ion selectivity and channel inhibition in Panx1.

253 ore were more likely to affect gating and/or ion selectivity than those in the upper pore.

254 ure, pharmacology, activation, inactivation, ion selectivity, and arrhythmias.

255 s for selective ion conduction and efficient ion separation.

256 In general, the secondary ion signals were significantly enhanced by up to 3 order

257 Here we report a lithium-ion solid electrolyte substrate, demonstrating its appli

258 iway junctions or pseudoknots in mixed metal ion solutions.

259 performance of DBDI-MS and potentially other ion sources involving high voltage waveforms.

260 ate-adducted GPLs yields diagnostic fragment ions spaced 24 Da apart.

261 Based on ion specificity, an adsorption-repulsion mechanism, we s

262 lexes into the gas phase as multiply charged ions suitable for mass spectrometric analysis.

263 itive for TFA mobile phases, which mitigates ion suppression through a similar mechanism but in a mor

264 -woven grids, followed by the removal of the ion template, result in a wholly organic molecular mater

265 of heterogeneous spatial sequences of metal ions that we describe, depending on the metal and synthe

266 n, we used the biologically relevant calcium ion to investigate the conformation of monomeric aSyn in

267 With high initial ratio of calcium ion to phosphate, periodic precipitation was obtained ac

268 odifies the Li(+) substructure causing Li(+) ions to bind more strongly to the host framework S(2-) a

269 tribute to controlling the movement of toxic ions to leaves and, therefore, can be seen as a mechanis

270 aining polyatomic species ranging from small ions to nanocrystals and large protein complexes.

271 mponent in the sample and correlates product ions to their corresponding precursor ions.

272 Since ion transfer is diffusion-limited, by changing the volta

273 publications have demonstrated the tuning of ion-transfer (IT) processes across ion-selective membran

274 ite blocks the transmembrane-spanning sodium ion translocation pathway, providing a molecular mechani

275 We propose that dynamic regulation of ion transport and metabolic plasticity are required to m

276 The ion transport behavior in these materials can be regulat

277 A fundamental understanding of ion transport behavior in wood-based structures enhances

278 anation for varied substrate specificity and ion transport ratio among CCCs.

279 ation-induced assembly to enable directional ion transport via forming vertically aligned nanosheets

280 ergy transduction, contractile function, and ion transport.

281 tance of WNK's cellular degradation on renal ion transport.

282 The role of CCC1 ion transporter activity in the regulation of plant immu

283 Ion transporters are key players of cellular processes.

284 Using an ion trap quantum computer and protocols motivated by the

285 zation, transferred into a linear quadrupole ion trap, isolated, and subjected to collision-activated

286 ectrometry (MS2) fragmentation by CID in the ion trap.

287 drawback to performing targeted analysis on ion trapping instruments is the potential for increased

288 tal X-ray diffraction as a solvent-separated ion triplet with two potassium counterions.

289 rience significant volumetric changes during ion uptake/rejection, i.e., during doping/de-doping and

290 Experimental P(ion) values were high enough to explain observed cellula

291 The accumulation of Cu(+) ions via an ionic capacitive effect at the Schottky junc

292 then] -3-one (BTSIXO) conjugated with Fe(3+)-ions via very simple eco- friendly synthetic protocol.

293 ith chloride, acetate and formate as counter ions were employed to study the lipophilization reaction

294 the limited range of the concentration of Ru ions where the insulator-metal transition occurs.

295 o form coordination bonds with various metal ions, which can be reduced to metal nanoparticles (NPs)

296 r approach may be scaled to large numbers of ions with arbitrarily small separation and is a step tow

297 divergent opening of unsymmetrical phenonium ions with chloride ions.

298 tributions of specific interactions of metal ions with monomeric Abeta to their effects on bulk aggre

299 atives exhibit selectivity to Na(+) and K(+) ions within detection ranges of 0-100 and 0-50 mmol L(-1

300 d point defects, such as trivalent ytterbium ions (Yb(3+) ), have played a central role in the first