ライフサイエンスコーパス: ion conductance

1 nction (altered basolateral --> apical Cl(-) ion conductance).

2 but only A(A799I) exhibits an A(A799V)-like ion conductance.

3 l applications requiring chemical control of ion conductance.

4 ila neurons that was not based on changes in ion conductance.

5 this stabilization is a major determinant of ion conductance.

6 ggregates and the characteristics of induced ion conductance.

7 finity for the transmitter and no measurable ion conductance.

8 ion of epithelial calcium-activated chloride ion conductance.

9 p is independent of changes in E(m) or total ion conductance.

10 ly rises up to tenfold and is accompanied by ion conductance.

11 of the cardioprotective significance of this ion conductance.

12 leading to stronger and persistent membrane ion conductance.

13 nto the channel pore, creating a barrier for ion conductance.

14 ts and simulations define residues governing ion conductance.

15 opic current measurements because of its low ion conductance.

16 he latter phase concurrent with the start of ion conductance.

17 llular side of transmembrane domain three in ion conductance.

18 romoting vesicle aggregation, and regulating ion conductances, all in a Ca2+-dependent manner.

19 switches between an open state that permits ion conductance and a closed state that prevents permeat

20 o-tip direction, the funnel exhibits a lower ion conductance and a higher electroosmotic flow velocit

21 p-to-base direction, the funnel has a higher ion conductance and a lower electroosmotic flow velocity

22 We combined nanoscale live-cell scanning ion conductance and fluorescence resonance energy transf

23 in folding and design, and the mechanisms of ion conductance and gating, but also in more applicative

24 The temporal correlation between ion conductance and hydration of helices holds for fast

25 caling arises from the non-linearity between ion conductance and membrane shape.

26 showed a downregulation of genes involved in ion conductance and MOR-mediated signaling, as well as a

27 Herein, we have examined the barriers to ion conductance and origins of ion selectivity in models

28 We have developed a hybrid scanning ion conductance and scanning near-field optical microsco

29 t lumen width, through calculations of their ion conductance and selectivity based on all-atom molecu

30 00 side chains are major determinants of RyR ion conductance and selectivity.

31 O2, mediate the photocurrents with different ion conductance and selectivity.

32 pens the way to elucidating the mechanism of ion conductance and selectivity.

33 the plasma membrane that counteracts inward ion conductance and therefore limits neuronal excitabili

34 ties of these proteins, such as selectivity, ion conductance, and gating.

35 f PKC is required for PDBu activation of VR1 ion conductance, and is independent of the vanilloid sit

36 aracteristics, their expression of intrinsic ion conductances, and their responsiveness to chronic 6-

37 Our simulated ion conductance approaches that obtained experimentally

38 ional model in which detailed morphology and ion conductance are paired with intracellular ATP produc

39 Water efflux and the cessation of the ion conductance are synchronized as well, with a time co

40 c phospholemman, Mat-8 and renal CHIF, large ion conductances are activated when gamma subunits are e

41 urrent at -60 mV suggested that at least two ion conductances are involved in the pacemaking of the c

42 However, it is unclear which ion conductances are responsible for PKA-induced nocicep

43 APOL5 readily inserted into bilayers to form ion conductance at neutral pH, but required a positive v

44 nent of natural medicinal honeys, blocks the ion conductance but not the water flux through human Aqu

45 ese transitions are well-defined in terms of ion conductance, but their structural basis is poorly un

46 ed the ability to bind to PA pores and block ion conductance, but they were unable to translocate acr

47 These structural features explain high ion conductance by RyRs and the long-range allosteric re

48 n permeation free energy profile and maximum ion conductance calculated from the MS-EVB simulation da

49 that both mechanisms may lead to changes in ion conductances, cell excitability and Ca(2+) influx un

50 PPase signature residues located outside the ion conductance channel identified earlier in PPases usi

51 protein into the membrane bilayer to form an ion conductance channel.

52 Ion transport studies reveal ion conductance characteristics of individual BNNTPs, wh

53 and human AMs were characterized by scanning ion conductance, confocal, and electron microscopy.

54 novel method, we have recently described an ion conductance consistent with mitochondrial permeabili

55 ctive drug dexpramipexole (DEX) inhibited an ion conductance consistent with this c-subunit channel (

56 nanopipette probe technique that uses local ion conductance currents to image the physicochemical pr

57 owing in the rate at which a Mg(2+)-specific ion conductance deactivates following membrane excitatio

58 r buffer with submicrometer resolution using ion conductance distance control to demonstrate the feas

59 and the influence of the modified dipoles on ion conductance estimated.

60 +), explaining the >100 times larger maximal ion conductance for the latter, in qualitative agreement

61 rences in membrane insertion properties, the ion conductances formed by APOL1-4 were similarly pH-dep

62 ations on the elementary scaling behavior of ion conductance [Formula: see text] as a function of ion

63 Loss of CFTR-mediated chloride ion conductance from the apical plasma membrane of epith

64 nd assessed the impact of defective chloride ion conductance, genotype, and colonization status on mi

65 with that of genes involved in transmembrane ion conductances (i.e., channels), exocytosis, and rho/r

66 B011 was the most potent blocker of the AQP1 ion conductance (IC50 of 14 muM), with no effect on wate

67 t a method based on superresolution scanning ion conductance imaging of small synapses in culture at

68 suggest that Gly 230 is critical for normal ion conductance in hClC-1 and that this residue resides

69 and are found to irreversibly inhibit sodium ion conductance in recombinantly expressed wild-type sod

70 bic constriction is the major determinant of ion conductance in the GLIC pentameric ion channel.

71 n indole side chains have a direct impact on ion conductance in the gramicidin channel.

72 ny Kv channels undergo a progressive loss of ion conductance in the presence of a prolonged voltage s

73 In order to examine ion conductance in the stem of the channel, we used Venu

74 cyclosporine A (CSA) inhibited increases in ion conductance in whole rat brain-derived mitochondria

75 Specific ion conductances in subcellular compartments must also b

76 ttern results from combinations of intrinsic ion conductances, inhibitory and excitatory synaptic inp

77 The basic idea is that there is a change of ion conductance inside a nanopipet probe when it approac

78 The surface-charge-governed ion conductance is dominant for electrolyte concentratio

79 We show that ion conductance is mediated, in part, by hydrogen bondin

80 ce is presented that shows that the membrane ion conductance is not increased during the complete cyc

81 Two-pore domain potassium (K2P) channel ion conductance is regulated by diverse stimuli that dir

82 channelrhodopsins' mechanism of light-gated ion conductance is scarce, limiting its engineering as o

83 How ABC proteins regulate ion conductances is unknown, but must generally involve

84 re channels enhanced the permselectivity and ion conductance, leading to a larger osmotic voltage and

85 ning ion conductance microscopy (P-SICM) for ion-conductance measurement in polymer membranes and epi

86 f simultaneous quantitative voltammetric and ion conductance measurements and also identify a general

87 High-resolution ion conductance measurements through the Tom40 channel i

88 e substrate is a working electrode, and both ion-conductance measurements between the QRCEs in the tw

89 studies have also allowed us to identify the ion conductance mechanism and its relation to water move

90 Combined scanning electrochemical-scanning ion conductance microcopy (SECM-SICM) has been used to m

91 RCE) placed in a nanopipet tip of a scanning ion conductance microscope (SICM) and a conductive (work

92 namic flow through a nanopipet in a scanning ion conductance microscope (SICM) can exert localized fo

93 The scanning ion conductance microscope (SICM) is a powerful tool for

94 The scanning ion conductance microscope (SICM) is an emerging imaging

95 The scanning ion conductance microscope (SICM) is an emerging tool fo

96 , the nanopipette is used as both a scanning ion conductance microscope (SICM) probe and an injection

97 lize, but recent work has shown the scanning ion conductance microscope (SICM) to be a very promising

98 e was studied with a four-electrode scanning ion conductance microscope (SICM).

99 stems, as demonstrated herein for a scanning ion conductance microscope setup.

100 sible with previous versions of the scanning ion conductance microscope.

101 ingMode atomic force microscope and scanning ion conductance microscope.

102 characterization of a laser-coupled scanning ion-conductance microscope (SICM) integrated with TERS f

103 be the development of a bioinspired scanning ion conductance microscopy (bio-SICM) approach that coup

104 cently, we described potentiometric-scanning ion conductance microscopy (P-SICM) for ion-conductance

105 trumental technique, potentiometric scanning ion conductance microscopy (P-SICM), that utilizes a nan

106 h a technique termed potentiometric scanning ion conductance microscopy (P-SICM).

107 his paper, we used live correlative scanning ion conductance microscopy (SICM) and fluorescence confo

108 integrating plasmonic imaging with scanning ion conductance microscopy (SICM) and other scanning pro

109 nanopipet that enables simultaneous scanning ion conductance microscopy (SICM) and scanning electroch

110 The technique is based on scanning ion conductance microscopy (SICM) and, as a proof of con

111 gated ion channels into probes for scanning ion conductance microscopy (SICM) as a robust platform f

112 tein nanopores with high-resolution scanning ion conductance microscopy (SICM) extends the utility of

113 al imaging is demonstrated, using a scanning ion conductance microscopy (SICM) format.

114 Scanning ion conductance microscopy (SICM) has developed into a p

115 Scanning ion conductance microscopy (SICM) has emerged as a versa

116 Scanning ion conductance microscopy (SICM) is a nanopipette-based

117 Scanning ion conductance microscopy (SICM) is a powerful and vers

118 Scanning ion conductance microscopy (SICM) is a powerful techniqu

119 Scanning ion conductance microscopy (SICM) is a scanned probe mic

120 Scanning ion conductance microscopy (SICM) is a scanning probe te

121 Scanning ion conductance microscopy (SICM) is a super-resolution

122 Scanning ion conductance microscopy (SICM) is a topographic imagi

123 Scanning ion conductance microscopy (SICM) is becoming a powerful

124 Scanning ion conductance microscopy (SICM) is demonstrated to be

125 In this work, scanning ion conductance microscopy (SICM) is used for the first

126 ll surfaces that allows noninvasive scanning ion conductance microscopy (SICM) of cells and which mus

127 Scanning ion conductance microscopy (SICM) offers the ability to

128 Scanning ion conductance microscopy (SICM) offers the ability to

129 d use of nanoscale dual function pH-scanning ion conductance microscopy (SICM) probes is reported.

130 We report a novel scanning ion conductance microscopy (SICM) technique for assessin

131 oscience, particularly when used in scanning ion conductance microscopy (SICM) to determine, in a non

132 This paper reports on the use of scanning ion conductance microscopy (SICM) to locally map the ion

133 -based cGMP biosensor combined with scanning ion conductance microscopy (SICM) to show that functiona

134 Scanning ion conductance microscopy (SICM) was used to interrogat

135 Here, we combine scanning ion conductance microscopy (SICM) with a microelectrode

136 With scanning ion conductance microscopy (SICM), a noncontact scanning

137 ynchronously at the nanoscale using scanning ion conductance microscopy (SICM), a scanning nanopipett

138 electrochemical microscopy (SECM), scanning ion conductance microscopy (SICM), electrochemical scann

139 clamping, confocal microscopy, and scanning ion conductance microscopy (SICM).

140 We used scanning ion conductance microscopy and conventional cell-attache

141 Confocal immunofluorescence, scanning ion conductance microscopy and molecular analyses, in co

142 We conclude that scanning ion conductance microscopy can be used to follow the tim

143 Scanning ion conductance microscopy imaging of battery electrodes

144 ied by intact axons identified with scanning ion conductance microscopy in primary hippocampal cultur

145 We describe hopping mode scanning ion conductance microscopy that allows noncontact imagin

146 in-coated pit dynamics in living cells using ion conductance microscopy to directly image the changes

147 We used scanning ion conductance microscopy to image changes in the surfa

148 rements were performed by utilizing scanning ion conductance microscopy to measure the change in resi

149 We report the use of scanning ion conductance microscopy to measure the ion permeabili

150 a novel recording approach based on scanning ion conductance microscopy to resolve tight junction per

151 ing a combination of macropatch and scanning ion conductance microscopy we show that loss of Scn1b in

152 ing a combination of macropatch and scanning ion conductance microscopy we show that loss of Scn1b in

153 ining state-of-the-art electron and scanning ion conductance microscopy with molecular biology techni

154 ium imaging, Western blot analysis, scanning ion conductance microscopy, and patch clamp analysis.

155 Using nanoscale mechanoscanning ion conductance microscopy, we demonstrate that MTs cont

156 Using scanning ion conductance microscopy, we show that intercellular c

157 signals, using a combined nanoscale scanning ion conductance microscopy-Forster resonance energy tran

158 -controlled distance dependance via Scanning Ion Conductance Microscopy.

159 Here we present scanning ion-conductance microscopy (SICM) as an alternative appr

160 ording, we identified a novel determinant of ion conductance near the point of entry of permeant ions

161 les and may correlate to the uncoupled Cl(-) ion conductance observed experimentally in both prokaryo

162 on-selective, and calcium-activated vacuolar ion conductance of 320 pS (yeast vacuolar conductance, Y

163 he p.Q65P variant may increase stability and ion conductance of the transmembrane protein, and lysoso

164 The ion conductance of UiO-66-X channels follows the sequenc

165 lization with individual oligomers producing ion conductances of <10 pS/pore.

166 that conclusively explain ChR activation and ion conductance on the basis of chromophore isomerizatio

167 processes and despite a strong dependence of ion conductances on temperature.

168 glial stimulation did not affect transmural ion conductance or cell-impermeant dye flux but the base

169 es oriented toward the bilayer center on the ion conductance pathway for the Streptomyces K(+) channe

170 t be close to the extracellular mouth of the ion conductance pathway.

171 r entrance, with four portals leading to the ion conductance pathway.

172 eir ability to interact with lipids, opening ion conductance pathways in artificial membranes, and in

173 es into artificial lipid bilayer openings of ion conductance pathways.

174 We propose that these major ion conductances play an essential role in membrane volt

175 olecular determinants that define the unique ion conductance properties of this protein are not well

176 ransporters mediate multidrug resistance and ion conductance regulation.

177 RCEs in the electrolyte channels provides an ion conductance signal that is used to control and posit

178 of these residues was observed to affect the ion conductance, suggesting the seven His-144 to compris

179 Cross-correlation analysis revealed that ion conductance tallies with peptide backbone amide I vi

180 nonfunctional protein with severely reduced ion conductance that aggregates in the endoplasmic retic

181 The ion selectivity of a membrane ion conductance that is inactivated by extracellular cal

182 cking, but several studies have described an ion conductance that results from PLM expression in oocy

183 vious studies suggest that the unique set of ion conductances that drive spontaneous, rhythmic firing

184 Measurements of ion conductance through alpha-hemolysin pore in a bilaye

185 s reminiscent of earlier reports of possible ion conductance through PLN pentamers.

186 by a measurable change in the single channel ion conductance through pores of the ion channel-forming

187 diseases in which alterations in control of ion conductance through the central pore of ion channels

188 ulations, we investigated the feasibility of ion conductance through the pore of the bellflower model

189 nit, largely abolished basolateral potassium ion conductance (to a degree similar to that of kidney-s

190 or cell-impermeant dye flux but the baseline ion conductance was more variable in Sox10::CreER(T2+/-)

191 elucidate the cation permeability pathway of ion conductance, we performed cysteine scanning mutagene

192 changes in transmembrane potential (E(m)) or ion conductance, we studied electrical currents and drug

193 their permeability to dyes and small atomic ions (conductance) were not proportional.

194 Among them, Gln-56 is important for ion conductance, whereas Ser-63, Thr-250, and Asn-258 ar

195 ssium channels have been attributed to their ion conductance, which sets membrane potential and repol

196 of Dokdonia eikasta (KR2) results in passive ion conductance, with a high preference for potassium ov

197 ion-controlled to water-splitting controlled ion conductance, with a large ion current signature that

198 mutants (D4938N, D4945N) showed a reduced K+ ion conductance, with D4938N also exhibiting a reduced s