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1 o denaturation on cross-linked species using ion mobility.
6 d by buffers rich in He or H(2) that elevate ion mobility and lead to prominent non-Blanc effects.
10 -ICR MS by performing chemical formula-based ion mobility and tandem MS analysis for the structural c
16 re property of ETL indirectly impacts halide ion mobility as evident from the TiO(2)-assisted halide
19 atmospheric pressure, (ii) ambient pressure ion mobility-based instruments, and (iii) high flow rate
22 f molecular dynamics, quantum chemistry, and ion mobility calculations, to generate structures and ch
25 separation is achievable by using drift tube ion mobility coupled with high-resolution mass spectrome
29 althy controls using label-free quantitative ion-mobility data independent analysis mass spectrometry
30 rom the greater reduced mass contribution to ion mobility described by the Mason-Schamp relationship.
31 lecular weight and ion mobility in a trapped ion mobility device (timsTOF Pro) to devise a scan mode
32 data extraction workflow by inclusion of the ion mobility dimension for both signal extraction and sc
35 higher capacitance but suffer from inhibited ion mobility due to constriction of the GO interlayer sp
36 e ion mobility spectrum agree with the basic ion mobility equation when using nitrogen as drift gas a
37 alizing reproducible gas-phase measurements, ion mobility experiments are commonly conducted in the p
38 cids using low-pressure, ambient-temperature ion mobility experiments performed in a radio frequency-
39 in differential or field asymmetric waveform ion mobility (FAIMS) spectra depending on the ion geomet
40 und those envelopes to split in differential ion mobility (FAIMS) spectra in a manner dependent on th
41 drift cell that enables the determination of ion mobilities from "first principles", we directly dete
42 es, with recently special interest in native ion mobility (IM) and collision induced unfolding (CIU)
44 ding to their conformation in the gas phase, ion mobility (IM) coupled to mass spectrometry is an att
49 entary biophysical techniques, including MS, ion mobility (IM), CD, and FTIR spectroscopy assays.
51 ended liquid chromatographic separation, and ion mobility (IM)-MS for efficient separation and identi
52 tion-mass spectrometry (ESI-MS) and nano-ESI-ion mobility (IM)-MS with collision-induced unfolding (C
53 e of the correlation of molecular weight and ion mobility in a trapped ion mobility device (timsTOF P
54 to inhomogeneities in topography and lithium-ion mobility in both the inner- and outer-SEI, thanks to
55 et was used to evaluate the value of product ion mobility in identifying lipids in a complex mixture.
57 reviously acquired on traveling-wave (TWIMS) ion mobility in the context of native mass spectrometry
59 phase conformations which are resolved using ion mobility; in contrast, the inactive epimer, 3-epi-25
62 ternating electric field during differential ion mobility is critical for separation selectivity and
63 The coupling of SID, high resolution, and ion mobility is demonstrated for a variety of protein co
64 redictions also indicate that high magnesium ion mobility is possible in other chalcogenide spinels,
66 n accurate to, at best, +/-2% of the reduced ion mobility (K(0)) value of the chemical of interest.
67 intact HS saccharides are dissociated in an ion mobility mass spectrometer and collision cross secti
70 N) approach to deconvolute Fourier transform ion mobility mass spectrometry (FT-IMMS) drift time spec
74 iology, collision cross sections (CCSs) from ion mobility mass spectrometry (IM-MS) measurements are
75 ompounds have recently been established from ion mobility mass spectrometry (IM-MS) measurements.
76 electrospray ionization (ESI) together with ion mobility mass spectrometry (IM-MS) to study soluble
78 estigations of full-length UVR8 using native ion mobility mass spectrometry adapted for photoactivati
81 rmined by liquid extraction surface analysis ion mobility mass spectrometry of native and denatured p
83 ut of four ligands), together with DOSY NMR, ion mobility mass spectrometry, and X-ray structure resu
86 ng mutations that mimic phosphorylation, and ion mobility mass spectrometry, we show that successive
91 COSY, NOESY, DOSY) NMR spectroscopy, ESI-MS, ion-mobility mass spectrometry (IM-MS), AFM, and TEM.
94 otein complexes and are also compatible with ion-mobility mass spectrometry, paving the way for impro
95 into the electrospray interface of a trapped ion mobility-mass spectrometer for rapid diastereomer se
96 modifications to an Agilent 6560 drift tube ion mobility-mass spectrometer in order to perform robus
97 ent with the results obtained from cryogenic ion mobility-mass spectrometry (cryo-IM-MS) measurements
98 ydrophilic interaction liquid chromatography-ion mobility-mass spectrometry (HILIC-IM-MS) has shown a
100 lity of commercial instrumentation have made ion mobility-mass spectrometry (IM-MS) an increasingly p
102 ss section (CCS) measurements resulting from ion mobility-mass spectrometry (IM-MS) experiments provi
103 fication of features derived from untargeted ion mobility-mass spectrometry (IM-MS) experiments.
106 ented on a commercially available drift tube ion mobility-mass spectrometry (IM-MS) instrument and ut
112 to nanoparticles using atmospheric-pressure ion mobility-mass spectrometry (IM-MS), and we demonstra
115 Using native nano-electrospray ionisation ion mobility-mass spectrometry (nESI-IM-MS), we characte
116 on of microalgae extracts via traveling wave ion mobility-mass spectrometry (TWIM-MS) by two differen
117 geted ultraperformance liquid chromatography-ion mobility-mass spectrometry (UPLC-IM-MS) method was o
119 transmission electron microscopy, as well as ion mobility-mass spectrometry coupled to infrared (IR)
120 ed structures for lossless ion manipulations ion mobility-mass spectrometry platform (SLIM IM-MS), in
123 ere, we use kinetics measurements and native ion mobility-mass spectrometry to show that SERF mainly
124 the measurement of protein structures, with ion mobility-mass spectrometry, which provides shape and
126 es of the cluster formation and experimental ion mobility measurements (CoV dispersion plots) conside
128 ved fragmentation pattern, and complementary ion mobility measurements prior to ECD provided orthogon
129 spectrometry (MS) techniques, namely native ion mobility MS (IM-MS), collision-induced unfolding (CI
130 ere, we demonstrate that the combined use of ion-mobility MS and well-defined synthetic glycan standa
131 related point mutants by using tandem MS and ion-mobility MS as a function of collisional activation.
132 processing native mass spectrometry (MS) and ion mobility-MS data sets and provide a brief overview o
135 a native electrospray ionization drift tube ion mobility-Orbitrap mass spectrometer specifically des
137 tion (MALDI), including MALDI-MS imaging and ion mobility, particularly high-field asymmetric wavefor
138 IMS bands were assigned to the heterogeneous ion mobility profile of [C(18)H(18)O(10)-H](-), and cand
139 traveling wave (TW) based compression ratio ion mobility programming (CRIMP) approach within structu
140 ected superposition approximation (PSA), the Ion Mobility Projection Approximation Calculation Tool (
141 geted peptide quantification using a trapped ion mobility quadrupole time-of-flight mass spectrometer
142 ced postionization, or MALDI-2, to a trapped ion mobility quadrupole time-of-flight mass spectrometer
143 g powers but are ultimately limited in their ion mobility range because of the range of mobilities sp
144 based instrument, accurate K(0) values of an ion mobility reference standard need to be used for ion
146 for pyruvate kinase (MW ~ 233 kDa); however, ion mobility resolution for bovine serum albumin (MW ~ 6
147 ss" separations provide unprecedentedly high ion mobility resolving powers but are ultimately limited
155 and-release (CaR)-ESI-MS assay, carried with ion mobility separation prior to GBP "release" (i.e., Ca
160 tiplexing capability provided by the trapped ion mobility separation, allowing more than 200 peptides
161 of the instrument, including mass selection, ion mobility separation, and post-mobility fragmentation
163 , the instrument allows multiple pass cyclic ion mobility separation, with concomitant increase in re
166 e liquid chromatography (UPLC) coupled to an ion-mobility separation (IMS) quadrupole-time-of-flight
168 es wider mobility range ultrahigh-resolution ion mobility separations and expands on the ability of S
169 first time that the current state-of-the-art ion mobility separations benchmark at a CCS-based resolv
175 This novel field asymmetric time of flight ion mobility spectrometer (FAT-IMS) allows high repetiti
177 rimental characterization of the flexible DT ion mobility spectrometer (Flex-DT-IMS) with correspondi
181 compounds at ambient pressure using a tandem ion mobility spectrometer with a reactive stage between
182 lemented by coupling a 3D-printed drift tube ion mobility spectrometer, operated at atmospheric press
184 w field ion mobility, while field asymmetric ion mobility spectrometers (FAIMS) separate them by the
187 us, they are an excellent choice for compact ion mobility spectrometers with both high resolving powe
188 rrors were all within 1-2% of the drift tube ion mobility spectrometry (DTIMS) measurements, with low
190 lity to mass spectrometry makes differential ion mobility spectrometry (FAIMS) a powerful tool for is
191 Strong orthogonality between differential ion mobility spectrometry (FAIMS) and mass spectrometry
193 trategy using high-field asymmetric waveform ion mobility spectrometry (FAIMS) coupled to the Orbitra
194 d aerodynamic high-field asymmetric waveform ion mobility spectrometry (FAIMS) device into the phosph
196 e benefits of high field asymmetric waveform ion mobility spectrometry (FAIMS) for mass spectrometry
197 ass spectrometric analysis, field asymmetric ion mobility spectrometry (FAIMS) has previously been us
198 d to MS via a high-field asymmetric waveform ion mobility spectrometry (FAIMS) interface to evaluate
201 e coupling of high-field asymmetric waveform ion mobility spectrometry (FAIMS) separation into the LE
202 s, differential or field asymmetric waveform ion mobility spectrometry (FAIMS) was implemented at or
203 I-MS) coupled with field asymmetric waveform ion mobility spectrometry (FAIMS), predictive metabolic
204 itching using high-field asymmetric waveform ion mobility spectrometry (FAIMS), we identified multipl
209 /HS isomers may be resolved by gated-trapped ion mobility spectrometry (gated-TIMS) with negligible s
210 to study the potential of gas chromatography-ion mobility spectrometry (GC-IMS) to differentiate lact
211 ue termed high asymmetric longitudinal field ion mobility spectrometry (HALF-IMS), which allows separ
212 findings allow for integration of MS(2) with ion mobility spectrometry (IM-MS(2)) and lead to a strat
213 trace chemical detection techniques such as ion mobility spectrometry (IMS) and differential mobilit
214 ation (vt-ESI) technique in combination with ion mobility spectrometry (IMS) and mass spectrometry (M
215 rature electrospray ionization combined with ion mobility spectrometry (IMS) and mass spectrometry (M
216 T) electrospray ionization (ESI) paired with ion mobility spectrometry (IMS) and mass spectrometry (M
218 ctures for lossless ion manipulations (SLIM) ion mobility spectrometry (IMS) device capable of switch
219 ar gas chromatography (GC) column coupled to ion mobility spectrometry (IMS) has been explored to cla
221 MD) simulations, mass spectrometry (MS), and ion mobility spectrometry (IMS) in positive ion mode.
223 Native mass spectrometry (MS) coupled with ion mobility spectrometry (IMS) is emerging as an import
224 ion cross section (CCS) values obtained from ion mobility spectrometry (IMS) measurements were recent
226 F separation fields normally associated with ion mobility spectrometry (IMS) or differential mobility
227 olome of live microglial cells by drift-tube ion mobility spectrometry (IMS) quadrupole time-of-fligh
228 ork, we demonstrate the advantages of adding ion mobility spectrometry (IMS) separation to existing L
229 mance liquid chromatography (chip-HPLC) with ion mobility spectrometry (IMS) via fully integrated ele
233 yed a combination of mass spectrometry (MS), ion mobility spectrometry (IMS), and molecular dynamics
235 ically around a few microseconds or less for ion mobility spectrometry (IMS)-based separations on the
239 recursor ions are accumulated in the trapped ion mobility spectrometry (TIMS) cells and separated acc
240 light (Q-TOF) mass spectrometer with trapped ion mobility spectrometry (TIMS) enables a >250% increas
242 on liquid chromatography coupled to trapped ion mobility spectrometry (TIMS) for separation and tand
243 the combination of MALDI-2 with the trapped ion mobility spectrometry (TIMS) functionality of the in
246 CCS calibration accuracy with traveling wave ion mobility spectrometry (TWIMS) separations in structu
248 vitamin D from its inactive epimer; however, ion mobility spectrometry can distinguish the epimer pai
249 by liquid chromatography with traveling-wave ion mobility spectrometry coupled to high resolution mas
250 rpentine ultralong path and extended routing ion mobility spectrometry coupled to mass spectrometry (
252 at shows the potential of gas chromatography-ion mobility spectrometry for early detection of ventila
253 s that depend on the drift times measured by ion mobility spectrometry for repeating units released a
255 The dual separation in gas chromatography-ion mobility spectrometry generates complex multi-dimens
257 neumonia we determined if gas chromatography-ion mobility spectrometry is able to detect 1) ventilato
259 que combination of preseparation and trapped ion mobility spectrometry separation in the negative ion
260 ein, we report on the use of high-resolution ion mobility spectrometry separations in structures for
261 The combination of field asymmetric waveform ion mobility spectrometry with liquid chromatography-mas
262 te the use of coupled liquid chromatography, ion mobility spectrometry, and mass spectrometry (LC-IMS
263 ing wave, trapped, and high-field asymmetric ion mobility spectrometry, are evaluated for their abili
264 increase in applications of native mass and ion mobility spectrometry, especially for the study of p
266 loid-beta oligomers by mass spectrometry and ion mobility spectrometry, revealing functionally releva
269 esults suggested that paper spray ionization-ion mobility spectrometry-mass spectrometry (PSI-IMS-MS)
270 ere, we assess the ability of tandem-trapped ion mobility spectrometry-mass spectrometry (tandem-TIMS
271 phy (LC) followed by high resolution trapped ion mobility spectrometry-mass spectrometry (TIMS-MS) wa
273 amyloid intermediates using a combination of ion mobility spectrometry-mass spectrometry and gas-phas
274 loride ions using a novel technique coupling ion mobility spectrometry-mass spectrometry with infrare
276 el analytical method based on hybrid trapped ion mobility spectrometry-time-of-flight mass spectromet
280 pid screening method based on traveling-wave ion-mobility spectrometry (TWIMS) combined with tandem m
281 where mass-selected structural studies using ion-mobility spectrometry mass spectrometry (IMS-MS) cou
282 gnals were detected by multicapillary column ion-mobility spectrometry, of which 44 could be identifi
284 this effect, high-Field Asymmetric-waveform Ion Mobility Spectroscopy (FAIMS) has been proposed as a
289 an be obtained from measurements made of the ions mobility through a given gas, and such structural i
290 aper, laser ablation electrospray ionization ion mobility time-of-flight mass spectrometry (LAESI-IMS
291 abilities in general, and to this quadrupole-ion mobility-time-of-flight (Q-IM-TOF) mass spectrometer
292 re, we report the use of a quadrupole-cyclic ion mobility-time-of-flight mass spectrometer (Q-cIM-ToF
298 been achieved, owing to their high intrinsic ion mobility, which leads to interdiffusion and large ju
299 ons by the absolute value of their low field ion mobility, while field asymmetric ion mobility spectr
300 eation of CCS databases and the inclusion of ion mobility within identification criteria are of high