ライフサイエンスコーパス: ion source

1 s in organic materials with this new kind of ion source.

2 of ion liberation from a droplet in the ESI ion source.

3 ed out in an ionized, supersonic entrainment ion source.

4 zation (DESI) using a commercially available ion source.

5 try (AMS) system with a microwave-plasma gas ion source.

6 tation products for all ions generated in an ion source.

7 The Ar carries the CO(2) to the ion source.

8 O reactor in line with the gas-accepting AMS ion source.

9 been used to optimize the Agilent multimode ion source.

10 zation has been equipped with a C 60 cluster ion source.

11 luent to CO2 as required for function of the ion source.

12 n of the probe conjugate in the electrospray ion source.

13 etric steady-state continuous dual-nanospray ion source.

14 iloxane), which was not possible using a Ga+ ion source.

15 ometer fitted with a dual-inlet electrospray ion source.

16 cant compromise in the performance of either ion source.

17 e at m/z 303 because of fragmentation in the ion source.

18 mical cell incorporated into an electrospray ion source.

19 are demonstrated using a single sonic spray ion source.

20 and a buckminsterfullerene (C60(+)) primary ion source.

21 ization (DESI) using a modified electrospray ion source.

22 t altering the operational parameters of the ion source.

23 gmentation that occurs in the glow discharge ion source.

24 ld be coupled to a continuous, electrospray, ion source.

25 incorporating an indexed (i.e., multiplexed) ion source.

26 at the emitter electrode in an electrospray ion source.

27 ide ions produced in a remote external MALDI ion source.

28 ar stream through the reaction region of the ion source.

29 as developed applying the new rf plasma O(-) ion source.

30 desorption and ionization mechanisms of the ion source.

31 e, a nebulizer is a critical component of an ion source.

32 their subsequent degradation to (16)O in the ion source.

33 mmonium ions introduced with an electrospray ion source.

34 ometer (HRToF-CIMS) equipped with an acetate ion source.

35 crochannel", before entering the high-vacuum ion source.

36 1 cm; diameter: approximately 10 mum) as the ion source.

37 c conditions or sensitive positioning of the ion source.

38 ent density on its route toward and into the ion source.

39 without any interface or modification of the ion source.

40 (CIMS) equipped with an "inlet-less" NO3(-) ion source.

41 bed and directly transferred to the PI-TOFMS ion source.

42 ohydrates ions occurring in the electrospray ion source.

43 between monomer units necessitating a gentle ion source.

44 ersible reconfiguration of gas-inlets of the ion source.

45 ion already observed with the generally used ion sources.

46 rometry employing 15-keV Ga+ and 20-keV C60+ ion sources.

47 yproducts of common stoichiometric bromenium ion sources.

48 ns relative to other less explored energetic ion sources.

49 ed with both sheathless and sheathflow CE-MS ion sources.

50 potential new route to control laser-driven ion sources.

51 ly distinguish between positive and negative ions sources.

52 us includes a high-transmission electrospray ion source, a quadrupole mass filter, a bending quadrupo

53 To validate the design concept of this new ion source, a simple prototype using a single set of cyl

54 IMS) experiments that sample from continuous ion sources, a range of experimental advances have been

55 easing the cooling gas pressure in the MALDI ion source after adding an additional gas line was furth

56 This ion source allows three unique operation modes, each wit

57 The configuration of the ion source also allowed rapid switching (approximately 1

58 ce ratio of the gas was then analyzed by gas ion source AMS.

59 ignificant fragmentation occurs in the MALDI ion source and can be observed via delayed ion extractio

60 m x 1.5 mm and are mounted, together with an ion source and channeltron detector, in small, interchan

61 chips were integrated with a beta-radiation ion source and charge detector.

62 equipped with an intermediate-pressure MALDI ion source and demonstrate its suitability for "bottom-u

63 d to be obtained with the use of (i) a Cs(+) ion source and detection of H(-) and D(-) at low mass re

64 lect two pseudocapacitive oxides as electron-ion source and drain to enable the efficient transport o

65 TOF) mass spectrometry employing the "Vocus" ion source and ion-molecule reactor.

66 nterface for effective operation with an ESI ion source and joined to an MS using an ion funnel inter

67 An enclosure was designed to fit around the ion source and mass spectrometer inlet at atmospheric pr

68 n with a direct analysis in real time (DART) ion source and mass spectrometry (MS).

69 combination of surface ionization using a Ta ion source and resonant laser ionization using the two-s

70 counter gradient reduced salt buildup in the ion source and resulted in excellent repeatability.

71 mns is directed toward the multiplexed (MUX) ion source and sampled in a time-dependent, parallel man

72 rature of a drying tube inserted between the ion source and the electrical ion deflectors.

73 mples to the open air space between the DART ion source and the mass spectrometer inlet, with the ent

74 trophoretic motors, because the former is an ion source and thus increases the solution ionic strengt

75 H/D) exchange (electrospray ionization (ESI) ion source and ultra-high-resolution Fourier transform i

76 d for seven lipids using atomic (Ga+ or In+) ion sources and a buckminsterfullerene (C60(+)) primary

77 bility, ionization efficiency with different ion sources and detection modes, acid/base behavior, oct

78 eters were used, both having electron-impact ion sources and Faraday cup collector systems.

79 ng traveling-wave IMS (TWIMS) with different ion sources and faster IMS separations showed the transf

80 he method utilizes pulsed, dual electrospray ion sources and requires minimal instrument modification

81 rated to shield the LC from the high-voltage ion source, and method conditions were optimized to acco

82 nfluenced by the application of the VIP-HESI ion source, and overall HRMS instruments provided enhanc

83 The effects of key parameters of ion source, and their interactions on ESI response were

84 the electron capture reactions occur in the ion source, AP-ECD has been limited by its apparent inab

85 A pulsed dual ion source approach coupled with a hybrid triple quadrup

86 s in the direct analysis in real time (DART) ion source are commonly formed by proton transfer.

87 The ion sources are operated in opposite polarity modes wher

88 beam microscopy technology using a gas field ion source as a key enabler and combining it with specif

89 T FTICR with a modified Apollo electrospray ion source as part of a nanoflow liquid chromatography-F

90 also be more easily paired with fluctuating ion sources, as the corresponding fluctuations in resona

91 lines linked to the planet, is shaped by the ion source at Enceladus, and magnetospheric dynamics may

92 ), solvent- and gas-cylinder-free, hand-held ion source based on desorption atmospheric pressure chem

93 A novel ion source based on the principle of sonic spray ionizat

94 With the dual-sprayer ion source, both sprays are orthogonal to each other.

95 ce and a newly developed heated electrospray ion source (Bruker VIP-HESI) during QTOF experiments.

96 er and demonstrated the functionality of the ion source by detecting organic and chemical compounds f

97 n of the sample prior to introduction to the ion source by using thermogravimetry (TG) hyphenated to

98 Here, we show that plasma-coupled ion sources can produce cryogenic lamellae of vitrified

99 10k instrument is equipped with an improved ion source, capable of switching between different reage

100 The predicted improvements in ion source characteristics are desirable for application

101 The ion source comprises a pulled quartz pipette with a sub-

102 An ion source concept is described where the sample flow is

103 lume and correct the signal change caused by ion source contamination and the matrix effect to evalua

104 r ESI-MS: it avoids both ion suppression and ion source contamination.

105 dependently applied and controlled, the dual ion source could be operated in ESI-only, APCI-only, or

106 The samples were analyzed with a nanoESI ion source coupled to a FT-ICR-MS (limit of detection fo

107 The apparatus employs an electrospray ion source coupled to a high transmission electrodynamic

108 data from a high repetition rate laser MALDI ion source coupled to a triple quadrupole mass spectrome

109 rnene was accomplished in a pulsed discharge ion source coupled with a supersonic molecular beam.

110 ssure, helium microwave-induced plasma (MIP) ion source coupled with an orthogonal acceleration time-

111 xAsy clusters detected using several primary ion sources (Cs+, Bi+, Bi3+, Bi32+, Bi52+, C60+, and C60

112 ular pressure of the N(2) cooling gas in the ion source, delay between the two laser pulses, and that

113 Use of a chiral cyanide ion source, derived from KCN and quaternary ammonium bro

114 se it can be implemented using a stand-alone ion source device suitable for use with any existing or

115 idered as a future candidate in laser-driven ion sources driven by the upcoming next generation of mu

116 s is demonstrated against another polyatomic ion source (e.g., SF(5)(+)).

117 oximately 1-10 Torr) of atmospheric pressure ion sources (e.g., electrospray ionization (ESI) for mas

118 f less than approximately 1% with continuous ion sources (e.g., ESI).

119 zation efficiency is achieved for continuous ion sources [e.g., electrospray ionization (ESI)].

120 roduction of gas phase imidazole into the ES ion source effectively protects gas phase protein-ligand

121 Electrospray ion sources efficiently produce gas-phase ions from prot

122 aims to compare the efficiency of different ion sources (Eletrospray Ionization-ESI and Atmospheric

123 The ion source employs a simple pneumatic spray operated at

124 ness of the technique coupled with nanoscale ion sources enabled the creation of such species.

125 ometry (MS) that in combination with ambient ion sources enables the atmospheric pressure investigati

126 electrospray ionization (nESI) is a powerful ion source enabling direct mass spectrometry (MS) analys

127 Here, an ion source equipped with laser triangulation for analyzi

128 e full 20-keV kinetic energy provided by the ion source extraction voltage as the collision energy in

129 n and modest technical requirements of these ion sources favors their employment in mobile applicatio

130 miniaturization and functionalization of an ion source for (portable) mass spectrometry (MS).

131 ocedure, the nanoparticles acted as aluminum ion source for alizarin complexone-Al(3+)-F(-) complex f

132 ative study illustrates that PIR-LAESI is an ion source for ambient mass spectrometry applications.

133 on for sputtering and a bismuth liquid metal ion source for analysis, both surfaces of leaves and fru

134 We describe a novel ion source for analytical mass spectrometry based on fem

135 (AP-ECD) experiments; repurposing the AP-ECD ion source for AP-CS requires only adding a supplemental

136 The utility of this ion source for comprehensive chemical analysis of a seri

137 y, photoionization (PI) was evaluated as the ion source for GCxGC-TOF-MS measurements.

138 interfaced to a commercial field desorption ion source for high-resolution, high-mass accuracy measu

139 ospheric pressure chemical ionization (APCI) ion source for mass spectrometry imaging.

140 The analytical characterization of a novel ion source for mass spectrometry named array of micromac

141 ation (LAAPPI), a novel atmospheric pressure ion source for mass spectrometry.

142 lectrospray ionization (LAESI) as an ambient ion source for mass spectrometry.

143 orne laser plasma is suggested as an ambient ion source for mass spectrometry.

144 The optimal ion source for preparing biological lamellae is identifi

145 ysis process inherent to operation of the ES ion source for selective ionization.

146 tween the membrane and the mass spectrometer ion source for the determination of SVOCs in complex mix

147 axis dynode/multiplier arrangement, or as an ion source for the IMS drift cell.

148 nd general applicability as a self-contained ion source for the liquid sample introduction.

149 pulsed glow discharge is used as a versatile ion source for time-gated generation of elemental, struc

150 microplasma devices attractive candidates as ion sources for miniaturized mass spectrometry and other

151 Ion sources for molecular mass spectrometry are usually

152 strate its functionality at two laser-driven ion sources for quantitative online determination of the

153 Argon cluster ion sources for sputtering and secondary ion mass spectr

154 MALDI) method has been used with an external ion source Fourier transform mass spectrometer (FIMS) to

155 en the FTMS has a vibrationally cooled MALDI ion source, fragile glycolipids can be desorbed from TLC

156 revents neutral molecules originating in the ion source from impacting the surface, an ultrahigh vacu

157 With the external ion source FTMS instrument, ions made by MALDI are injec

158 relation of the analyzer performance with an ion source function and provides the improved dynamic ra

159 en positive ion mode APCI with oxygen as the ion source gas was employed to ionize saturated hydrocar

160 The CD ion source generates in air H(3)O(+)(H(2)O)(n) and NO(+)

161 rometry (AMS) and further development of gas ion sources (GIS), a reduction of sample size down to mi

162 This new rf plasma oxygen primary ion source has been applied to the localization of essen

163 A new ion source has been developed for rapid, noncontact anal

164 ng buckminsterfullerene (C60) as the primary ion source has the ability to generate chemical images o

165 ant improvements have been made in the Cs(+) ion source, high voltage (HV) control, stage reproducibi

166 using a fully automated chip-based nanospray ion source in both positive and negative ion mode.

167 to laser positioning, creating a more robust ion source in comparison to static AP-MALDI.

168 Operation of the ion source in spray-only mode shows superior performance

169 The performances of this primary ion source in terms of current density and achievable la

170 the latter system, the presence of chloride ion source in the starting solutions used for the perovs

171 n adaptation of the multiplexed electrospray ion source in which only two of the sprays are utilized.

172 role of ionization efficiencies of different ion sources in instrument sensitivity was compared using

173 e ionization mechanisms involved in the dual ion source include Penning ionization, ion molecule reac

174 a naturally occurring phenomenon in various ion sources including soft ionization techniques such as

175 imitations of conventional electrospray-type ion sources, including the need for high charging potent

176 found with C60(+) relative to the other two ion sources, indicating great promise for future cellula

177 try-independent low-temperature plasma (LTP) ion source integrated into a hand-held head unit (2 kg)

178 ticles in the higher-pressure regions (e.g., ion source interfaces) of mass spectrometers, thus provi

179 performance of DBDI-MS and potentially other ion sources involving high voltage waveforms.

180 ng atmospheric-pressure afterglow (AeroFAPA) ion source is based on a helium glow discharge plasma, w

181 The ion source is capable of producing predominately multipl

182 The functionality of this ion source is demonstrated with mass spectrometric and i

183 nexpensive, miniature low-temperature plasma ion source is detailed.

184 A buckminsterfullerene ion source is employed to characterize peptide-doped tre

185 The performance of the nESI ion source is evaluated by measuring the collision cross

186 or increased and the reproducibility of the ion source is increased.

187 The miniature low-temperature plasma ion source is operated in a "flow-through" configuration

188 erature plasma ionization with the miniature ion source is shown to be a promising technique for the

189 the most appealing mode of operation of the ion source is the DEMI mode which allows the simultaneou

190 ass spectrum when the low-temperature plasma ion source is used in the flow-through configuration.

191 ace (OPI) coupled to an atmospheric pressure ion source is used to capture, dilute, focus, and transp

192 isted laser desorption ionization (AP-MALDI) ion sources is demonstrated.

193 nging, improving signal with cluster primary ion sources is of interest.

194 n opposite polarity modes whereby one of the ion sources is used to form analyte ions while the other

195 This combination of ion sources is well-suited to implementation of experime

196 MS), which uses a carbon fiber bundle as the ion source, is useful for the analysis of small organics

197 ght the analytical utility of this transient ion source, it was connected to a gas chromatograph for

198 They include: sensitive ion sources, loss-free interfaces, ion optics components

199 Thanks to a stage movable in xyz, the ion source maintained an optimal vertical distance betwe

200 l achieved for lipids from an atomic primary ion source makes cell-imaging experiments challenging, i

201 However, TLC can be coupled to an external ion source MALDI-Fourier transform (FT) MS instrument wi

202 The instrument features four parallel ion source/mass analyzer/detector channels assembled in

203 ) array mass spectrometer with four parallel ion source/mass analyzer/detector channels has been buil

204 These ion sources may comprise high ion currents with composit

205 er-driven, high-current, quasi-monoenergetic ion sources may enable significant advances in the devel

206 GC x GC-HR-ToF MS with a multimode ion source (MMS) offers consecutive runs in EI and ECNI

207 is employed for direct air analysis, without ion source modification, by using the sheath gas as the

208 h, including fiber test, laser coupling and ion source modification.

209 ed molecular mass by electrospray ionization ion source MS is 9898 Da, and the molecular mass of the

210 Images have been generated with a Au primary ion source near the static limit of 10(12) ions/cm2.

211 This study shows that ion source non-linearities in hydrogen analysis require

212 Ion source nonlinearities are characterized over a wide

213 All results are corrected for ion source nonlinearities characteristic of hydrogen ana

214 extract is transferred to the tritium-based ion source of a drift-tube ion mobility spectrometer.

215 h-pressure gas chromatograph to the internal ion source of a Fourier transform ion cyclotron resonanc

216 is placed directly into a specially designed ion source of an external source Fourier transform mass

217 esult is a focusing, magnetic field-directed ion source of multiple species with strongly enhanced en

218 ticles of various sizes were measured in the ion source of the mass spectrometer and follow a Gaussia

219 ure chemical ionization were investigated as ion sources, of which the latter showed a higher ionizat

220 Earlier work using a modified MUX ion source on an orthogonal acceleration time-of-flight

221 introduction of an rf plasma oxygen primary ion source on NanoSIMS enabled higher lateral resolution

222 The performance of this ion source on the oaTOF mass spectrometer is compared wi

223 The applicability of the ion source operated in desorption electrospray ionizatio

224 A Grimm-type glow discharge ion source, operated in the microsecond pulsed mode, has

225 iments using an ultraviolet (UV) laser-based ion source operating at atmospheric pressure are describ

226 ed desorption/ionization (AP-MALDI), several ion sources, operating in a range of geometries have bee

227 Ion source operation in the MICI-only mode is particular

228 pplicable analytical LC/HRMS method based on ion source optimization, data treatment optimization on

229 ositive and negative mode can be achieved by ion source optimization, respectively.

230 vo G2-S Q-TOF from Waters-Micromass using an ion source originally designed for atmospheric pressure-

231 The ion source performance and its ability to analyze variou

232 Since the ion source performance depends on the transfer of analyt

233 This emerging field, which involves various ion source platforms such as matrix-assisted laser desor

234 ) in a MALDI source differs according to the ion source pressure and on the mass analyzer used.

235 bination of serial FIB/SEM with plasma-based ion sources promises a framework for targeting specific

236 thod requires only minor modification of the ion source region of the mass spectrometer and is shown

237 Errors can be reduced 5-fold when the ion-source residence time of CO2+ is decreased by use of

238 ization of ketones using this ultrasensitive ion source reveals a stepwise conversion from directly i

239 plex mixtures of saturated hydrocarbons, the ion source should be purged of air to remove nitrogen an

240 Humidity at such plasma-based ion sources should be regulated to avoid approximately 9

241 e coupled to a secondary electrospray (SESI) ion source, so the adsorption sampling filters are therm

242 riles unless a catalytic amount of a lithium ion source, such as LiBH(4) or lithium tetraphenylborate

243 Other self-aspirating ion source systems including atmospheric pressure photoi

244 We also address the effect of ion source temperature on native protein-ligand complex

245 The ion source temperature was varied in order to study the

246 Presented here is a novel multimode ambient ion source termed desorption electrospray/metastable-ind

247 Here, we present a new ion source that combines the previously published extend

248 Here we report a nanopore ion source that delivers ions directly into high vacuum

249 spectrometer to which we have added a MALDI ion source that incorporates a sample stage constructed

250 a novel, electrical discharge-based reagent ion source that is located in the first differentially p

251 Direct analysis in real time (DART) is an ion source that permits rapid mass spectrometric detecti

252 chnology have been focused on generating new ion sources that can in turn be used to eject more intac

253 ecular ions are formed simultaneously in the ion source, thereby complicating the spectra (>12 000 pe

254 ive ion mode, comparing it with conventional ion sources through the analysis of complex lipid liver

255 hat is connected through a microelectrospray ion source to a tandem mass spectrometer.

256 many trace metals requires an oxygen primary ion source to allow the generation of positive secondary

257 new instrument that couples an electrospray ion source to an injected-ion drift tube/time-of-flight

258 zation (MALDI-2) and by adapting a t-MALDI-2 ion source to an Orbitrap mass analyzer.

259 Notably, facile switching of the ion source to atmospheric-pressure chemical ionization w

260 and neon ion beams generated by a gas field ion source to irradiate the sample.

261 We employ a buckminsterfullerene ion source to probe the distribution of histamine molecu

262 on transfer reactions within an experimental ion source to remove excess charge from sample ions and

263 ass spectrometers, relocation of the reagent ion source to the front of the mass spectrometer enables

264 directly connecting the atmospheric pressure ion source to the vacuum mass analyzer region; it has no

265 successfully ionized by the contained nAPCI ion source under ambient conditions, with the correspond

266 same quality of images as the cesium primary ion source used to produce negative secondary ions (C(-)

267 In this paper, a new type of an oxygen ion source using a rf plasma is fitted and characterized

268 we demonstrated a facile method to fabricate ion sources using a laser printer for ambient ionization

269 the ionization mechanisms of a two-ring DBDI ion source, using different discharge gases to analyze v

270 liquid samples, which were introduced to the ion source via a direct liquid interface, to enable the

271 The LTQ-Orbitrap with a MALDI ion source was adopted to achieve MS imaging in high mas

272 A geometry-independent version of the DESI ion source was also coupled to the miniature mass spectr

273 ge, microwave-induced-plasma (GDMIP), tandem ion source was developed, characterized, and used in con

274 at the emitter electrode of an electrospray ion source was effectively controlled by incorporating a

275 cross talk for the multiplexed electrospray ion source was evaluated as a function of analyte concen

276 The DART ion source was maintained at 300 degrees C, while the TD

277 The MALDI ion source was operated at intermediate pressure to cool

278 h-voltage emitter contact in an electrospray ion source was shown to provide for new types of electro

279 rometry employing an SF5+ polyatomic primary ion source was utilized to obtain a series of in-depth p

280 sult and the reaction using a chiral hydride ion source, we propose a reaction pathway in which a Bro

281 of every possible component of the different ion sources, we finally were able to embed two emitters

282 atmospheric pressure photoionization (APPI) ion sources were compared.

283 These ion sources were investigated in terms of their suitabil

284 Ions, generated by the atmospheric pressure ion source, were directed by the inlet along the axis of

285 This new cluster ion source, when operated at an incident energy of 20 ke

286 CO(2) that is formed to the AMS instrument's ion source, which is appropriately modified for use with

287 y quadrupole mass filtering from a discharge ion source, which is relatively inefficient, or by switc

288 icient, or by switching the gas/vapor in the ion source, which is relatively slow.

289 opportunities for the development of bright ion sources, which will advance both analytical and prep

290 uating to 57% (v/v) net concentration at the ion source) while neither compromising the favorable PGC

291 ent, a prototype instrument that combines an ion source with a commercial electrospray ionization/mat

292 on process using an Agilent jet stream (AJS) ion source with a digestion efficiency close to or more

293 Ions are generated in an electrospray ion source with a sampling cone interface and two stacke

294 assisted laser desorption/ionization (MALDI) ion source with an ion trap mass analyzer, with particul

295 mmercial direct analysis in real time (DART) ion source with an ion trap mass spectrometer, native ch

296 be sensitive to analyte pressure in the IRMS ion source with or without carrier gas admitted with ana

297 section measurements to be made between both ion sources with minimal differences in the instrumental

298 ting pathway linking the redox reaction H(+) ion sources with the CF(0) H(+) channel.

299 ion from different samples migrates into the ion source within a short time interval ( approximately

300 s obtained on a commercial mass spectrometer ion source without physical instrument modifications usi