ライフサイエンスコーパス: ionic channel

1 gatively charged subnanometer-sized confined ionic channels.

2 and CCK-8, which operate through independent ionic channels.

3 ake, but may be due to a secondary effect on ionic channels.

4 ndent properties in two molecularly distinct ionic channels.

5 those of gating current records reported for ionic channels.

6 to variability in the types and densities of ionic channels.

7 5 other G-protein-coupled receptors or on 15 ionic channels.

8 role in recently discovered mechanosensitive ionic channels(23).

9 n translocation into liposomes and to elicit ionic channel activity at the phospholipids low affinity

10 h-clamped, providing the first recordings of ionic channel activity, synaptic vesicle release, and ga

11 fabricating angstrom-scale artificial solid ionic channels aiming to replicate the biological ion ch

12 ese operations, involving synapses, membrane ionic channels and changes in membrane potential, are th

13 Ionic channels and gap junctions are remodeled in cells

14 des a handle for optimization of radical and ionic channels and yields accelerations up to 1 order of

15 teins, including receptors, transporters and ionic channels, and to be active mostly as a homodimer.

16 Ionic channels bathed in mixed solutions of two permeant

17 reproducible conductance levels expected for ionic channels, Bax, but not Bcl-xL, created arbitrary a

18 nd lipid uptake through a temporarily stable ionic channel) become dominant in model liposome systems

19 nlinear DeltaV(m), we studied the effects of ionic channel blockers on DeltaV(m) in geometrically def

20 in cell cultures by measuring the effects of ionic channel blockers on DeltaVm and measuring uptake o

21 models with many compartments and dozens of ionic channels can account for this Ca(2+) spike-depende

22 n with the rapid movement of calcium through ionic channels can cause large external calcium fluctuat

23 changes include alterations at the levels of ionic channels, cellular energy balance, neurohormonal e

24 We incorporated these parameters into a nine ionic channel conductance model to obtain completed mode

25 h as adenosine)-mediated response and not in ionic channel coupled receptor (such as GABA(A))-mediate

26 tal data sets on AF-induced changes of major ionic channel currents (ICaL, IKur, Ito, IK1, IKs, INaCa

27 duced in the model by inhibiting appropriate ionic channel currents according to experimentally repor

28 ctifier potassium current) or block multiple ionic channels (e.g., ibutilide and azimilide) in order

29 lity of SOICs such as three-dimensional (3D) ionic channels, excellent thermal stability, dual functi

30 systems, suggesting that the coregulation of ionic channel expression, by thus linking their variabil

31 is interpreted as due to its passage through ionic channels for both Na+ and K+.

32 Kinetics of voltage-gated ionic channels fundamentally reflect the response of the

33 gate age- and chamber-specific expression of ionic channels in the developing fetal mouse.

34 merous ion channels, to simplified, grouping ionic channels into a minimal set of variables.

35 ionic transport through porous membranes and ionic channels is important in numerous applications ran

36 Selective and rapid regulation of ionic channels is pivotal to the understanding of physio

37 Such a coregulation of ionic channels is uniquely observable in a cell speciali

38 In this review, we focus on the principal ionic channels (KATP, Nav, and Cav channels) involved in

39 he dynamic clamp and voltage-gated potassium ionic channels (Kv1.3) expressed in Xenopus oocytes.

40 Additional experiments examined the membrane ionic channels mediating these GluR activation effects.

41 biological "fusion pores" can be as small as ionic channels or gap junctions, one model posits a prot

42 altered current density primarily impact the ionic channel pore and those associated with altered res

43 hy causes remodelling, leading to changes in ionic channel, pump and exchanger densities and kinetics

44 t the cellular scale this remodelling of the ionic channels, pumps and exchangers gives rise to chang

45 ative interactions between voltage-dependent ionic channels remains largely unknown.

46 or agents that are neuroprotective or affect ionic channels; straightforward transduction of gene exp

47 expressed in a "retrograde" manner with the ionic channel that is modulated appearing early in devel

48 lyamine macromolecules, forming a network of ionic channels that exhibit regulated permeability of wa

49 affects the conductances and kinetics of the ionic channels that underlie neuronal activity.

50 The various abnormalities in ionic channels, transporters, kinases and various signal

51 The nature of the ionic channels underlying the excitatory actions of BK i