戻る
「早戻しボタン」を押すと検索画面に戻ります。 [閉じる]

コーパス検索結果 (１語後でソート)

通し番号をクリックするとPubMedの該当ページを表示します
1 respectively, from the 5- and 1-positions of isatin.
2  the skeleton of the naturally occurring dye isatin.
3 dolines, indolin-2-ones, indolin-3-ones, and isatins.
4 iyama aldol reaction of 2-siloxyindoles with isatins.
5 -ones was synthesized from the corresponding isatins.
6 enyl)-3-phenylurea 9a,b to the corresponding isatin 10a-f in ethanol containing a quantitative amount
7 fluoro phenoxymethyl)-pyrrolidine-1-sulfonyl)isatin ((18)F-ICMT-11), has been developed for use in PE
8  in intermolecular [4+2] cycloadditions with isatins 2a-2f to form 2-oxindole spirolactones 3a-3l.
9 n patterns, and is applicable to unprotected isatins 2b-2f bearing free NH-functionalities.
10 ased around the lead compound NSC73306 (1, 1-isatin-4-(4'-methoxyphenyl)-3-thiosemicarbazone, 4.3-fol
11                    Two of these analogues, 1-isatin-4-(4'-nitrophenyl)-3-thiosemicarbazone (22, 8.3-f
12 semicarbazone (22, 8.3-fold selective) and 1-isatin-4-(4'-tert-butyl phenyl)-3-thiosemicarbazone (32,
13 od for making isatoic anhydride-8-amide from isatin-7-carboxylic acid as a tool to easily produce a r
14 ing Lambert salt-initiated hydroarylation of isatin, a diverse array of monoarylated products, symmet
15                  Moreover, the 7-position of isatin, a potential cytochrome P450 hydroxylation site,
16  FAD, and this ligand superimposed well with isatin, a reversible inhibitor of MAO-B, when the struct
17                                              Isatin, a specific ANP receptor antagonist, reversed ANP
18 e have synthesized a novel series of N-alkyl isatin acylhydrazone derivatives and have identified and
19                These novel 6-methoxy-N-alkyl isatin acylhydrazone derivatives exhibited high CB2 func
20  discovered and reported a series of N-alkyl isatin acylhydrazone derivatives that are potent CB2 ago
21  three-component reactions using substituted isatins, alpha-amino acids, and cyclopropenes.
22  3-functionalized 2-oxindoles by varying the isatin, amine, and alcohol components.
23 been established, which efficiently assembly isatins, amino-esters and 2,3-allenoate into enantioenri
24 0 ng/ml), ANP (1 pM to 1 micromol/L), and/or isatin, an ANP receptor antagonist.
25                                    While the isatin analogues were generally less effective at CE inh
26 e (T(1)) is responsible for cleavage into an isatin and a 1,1-diarylethene by an initial C-C bond sci
27                                 Synthesis of isatin and iodoisatin from 2'-aminoacetophenone was achi
28 cedure was investigated with a wide range of isatin and phenol derivatives; moreover, the reaction me
29 ith substitution at various positions of the isatin and the 2-siloxyindole being tolerated.
30 eta-unsaturated oxindoles by the reaction of isatins and 2-chloropyridinium salts in EtOH at room tem
31 h catalytic decarbonylative coupling between isatins and alkynes, which provides a unique way to synt
32 ediated tandem reaction of easily accessible isatins and allenoates to functionalized 3-alkenyl-2-oxi
33 ed reaction proceeds via spiro-annulation of isatins and allenoates.
34 ith azomethine ylides generated in situ from isatins and alpha-amino acids has been elaborated, affor
35 of azomethine ylides, generated in situ from isatins and azetidine-2-carboxylic acid, with different
36 cade reaction of 3-alkylidene oxindoles with isatins and o-quinones.
37 tution reaction of 2-chloropyridinium salts, isatins, and amines in ethanol at room temperature.
38 tioselective vinylation of alpha-ketoesters, isatins, and imines to deliver a range of synthetically
39 n scope, scalable, applicable to unprotected isatins, and provides efficient access to 3-hydroxyoxind
40 rent classes of inhibitors: peptidomimetics, isatins, and pyrimidoindolones.
41                                              Isatins are a class of compounds that target activated c
42 been accomplished from the readily available isatin as a single starting material.
43  has been developed, employing N-substituted isatins as carbonyl substrates, and urea and alkyl aceto
44 c sequence has been demonstrated also for an isatin bearing fluorine substituents on the aromatic rin
45 new compounds having benzothiophene, indole, isatin, benzofuroxan, benzofurazan, benzothiadiazole, an
46        Treatment with the antiviral compound isatin beta-thiosemicarbazone (IBT), a compound that was
47 ults in resistance to the anti-poxvirus drug isatin-beta-thiosemicarbazone (IBT).
48  combinatorial method, variants of the basic isatin-beta-thiosemicarbazone structure were prepared an
49 ncreased resistance to the antipoxviral drug isatin-beta-thiosemicarbazone, suggesting that these mut
50  temperature-sensitive mutant, Cts56, and an isatin-beta-thiosemicarbazone-dependent deletion mutant,
51 nd substitution around the N4-phenyl ring of isatin-beta-thiosemicarbazones (IBTs), to identify compo
52                                      Several isatin-beta-thiosemicarbazones from our initial study ha
53 Potent and much more selective N-aminomethyl-isatin-beta-thiosemicarbazones were discovered.
54                             In contrast, the isatins bind to caspase-3 with significant heat release
55  addition, enzyme activity is abolished upon isatin binding to one active site of the homodimer resul
56 ntrast, the reversible competitive inhibitor isatin binds to all known MAO B and MAO A with similar a
57 nine Ni(II) complex with amides, imides, and isatins catalyzed by base afforded modified Ni(II) compl
58 ddition of terminal ynamides to a variety of isatins, catalyzed by a bisoxazolidine copper complex un
59                  The superior performance of isatins compared to other carbonyl based dienophiles was
60 Interestingly, the inhibitory potency of the isatin compounds was related to their hydrophobicity, su
61 harmacologically important thiazolidinedione-isatin conjugates in excellent yields and diastereoselec
62  reaction is compatible with a wide range of isatins containing electron-donating groups (EDGs) and e
63                      Functionalization of an isatin-containing Ni(II) complex through a 1,3-cycloaddi
64                                          The isatin core system is of immense importance due to the h
65                                              Isatin derivatives also underwent bisarylation with vari
66 ion of N-substituted thiazolidinediones with isatin derivatives has been developed "on water" to affo
67 (Z)-5-arylidene-1,3-thiazolidine-2,4-diones, isatin derivatives, and 1,2,3,4-tetrahydroisoquinoline (
68  pyrazoles, chromones, coumarins, xanthines, isatin derivatives, thiazolidindiones, (thiazol-2-yl)hyd
69                                  A series of isatin derived difluoronitromethyl substituted tertiary
70 n unprecedented aza-Michael reaction between isatin derived N-Boc ketimines and y-hydroxy enones.
71 uran framework was established starting from isatin-derived aldehydes and 2 equiv of 1,3-dicarbonyl c
72                         Herein, we depict an isatin-derived and 3,3'-disubstituted oxindole-appended
73 tric 1,3-dipolar cycloadditions (1,3-DCs) of isatin-derived azomethine ylide with allenes have been e
74 n efficient asymmetric aza-Henry reaction of isatin-derived ketimines has been achieved by using a ch
75 uaternary center (alpha-tertiary amine) from isatin-derived ketimines in the presence of vinyl seleno
76 za-Henry reaction of aryl nitromethanes with isatin-derived ketimines promoted by chiral monoamidine
77  annulation reaction was established between isatin-derived Morita-Baylis-Hillman (Is-MBH) alcohols w
78                     Our data suggest that an isatin-derived spirocyclic alpha-methylene-gamma-butyrol
79 em consisting of the core of naphthalene bis-isatin dimer and the terminal moieties of rhodanine, whi
80  is proposed to go through C-C activation of isatins, followed by decarbonylation and alkyne insertio
81 ious N-protected amino acids were coupled to isatin forming N-amino acylisatins.
82  derivatives containing an amide, imide, and isatin fragment through the Michael addition reaction is
83 ar iodine-promoted efficient construction of isatins from 2'-aminophenylacetylenes, 2'-aminostyrenes,
84 s, indazoles, benzotriazoles, indolones, and isatins gave analogues with weaker NR1A/2B activity than
85 steric modulators of potency (i.e., n-benzyl isatins) generated ligands that demonstrated similar or
86        Without alcohol, self-dimerization of isatins gives rise to tryptanthrin and its analogs.
87 e enantioselective allylboration reaction of isatins has also been shown on the basis of a kinetics s
88 ition of alpha,beta-unsaturated aldehydes to isatins has been developed.
89 etalated iridium(III) complexes derived from isatin-hydrazone Schiff bases with nanomolar IC(50) valu
90                                              Isatin hydrolase converts isatin to isatinate and belong
91    The high resolution crystal structures of isatin hydrolase from Labrenzia aggregata in the apo and
92        The functional proton wire present in isatin hydrolase isoform b represents a unique catalytic
93                                          The isatin hydrolase orthologues found in human gut bacteria
94 identification of orthologous genes encoding isatin hydrolases within the prokaryotic kingdom.
95                                              Isatin in a solution of dry N,N-dimethylformamide/NaClO(
96 ifunctional aromatic monomer (biphenyl) with isatin in superacidic media and further derivatization,
97 ng with commercially available 5-substituted isatins in nearly every case.
98 ion provides effective access to a series of isatin-incorporated phosphate-bearing 1,6-adducts having
99  and the cyclic ketones 1H-indole-2,3-dione (isatin), indenoquinoxaline-11-one and acenaphthenequinon
100                              Condensation of isatin (indole-2,3-dione) and 2-aminobenzamide led to th
101 assays and kinetic studies demonstrated that isatins (indole-2,3-diones), containing hydrophobic grou
102 ocatalytic method that achieves insertion of isatins into aryl difluoronitromethyl ketones under mild
103  (11) in 10 steps and 11% overall yield from isatin is reported.
104     A novel phosphonium-mediated reaction of isatins is described.
105 MAO B I199F mutant protein of MAO B binds to isatin (K(i) = 3 microM) but not to the three inhibitors
106 ad Ir(III) complex (1), bearing an imidazole-isatin ligand, shows high aqueous stability, maximum cel
107 xindoles was described via readily available isatin, malononitrile, allenoate, and amines.
108 ient five-component condensation reaction of isatin, malononitrile, secondary amines, alcohols, and m
109 nes, which are readily available with use of isatines, malononitrile, and 1,2-phenylenediamines under
110 he thiosemicarbazone and the reliance on the isatin moiety as key bioisosteric contributors.
111 es (3-fluoropropyl and 4-fluorobutyl) at the isatin nitrogen.
112      Assisted by the DG, the C-C cleavage of isatins occurs at room temperature.
113 ncluding benzanilide, acetanilide, oxindole, isatin, quinolinone, and maleimide, affording stable N-
114 ndmeyer reaction, followed by cyclization to isatin, reduction to indole with LiAlH4, and condensatio
115           A focused library incorporating an isatin scaffold was designed and evaluated for inhibitio
116 ion of a methoxy moiety in position 6 of the isatin scaffold.
117                                  A series of isatin sulfonamide analogs having a Michael acceptor wer
118                                  A number of isatin sulfonamide analogues were prepared and their pot
119 x between recombinant human caspase 3 and an isatin sulfonamide inhibitor has been solved to 2.8-A re
120                   In this study, a series of isatin sulfonamide Michael acceptors having a high nanom
121 r new fluorinated diastereo- and enantiopure isatin sulfonamide-based potent and selective caspase-3
122 ported peptide-based caspase inhibitors, the isatin sulfonamides derive their selectivity for caspase
123 tentially enhance the metabolic stability of isatin sulfonamides.
124  of isatoic-8-secondary amides (IASAs)) from isatin that take advantage of in situ capture of imidic
125 has been shown to generate species (indoxyl, isatin) that couple to yield indigo and indirubin.
126                                          The isatin-thiazolidine conjugate undergoes a catalyst-free
127                            Upon treatment of Isatin, THIQ with (Z)-4-arylidene-5-thioxo-thiazolidin-2
128 ation using the oxidative decarbonylation of isatin to form anthranilic acid as a fluorescent probe.
129                    Isatin hydrolase converts isatin to isatinate and belongs to a novel family of met
130 ns were carried out on several 5-substituted isatins to investigate the stability of sulfide adducts
131 addition of aryl acetonitrile to N-protected isatin under mild conditions has been developed.
132 opylenedioxythiophenes (ProDOTs) and N-alkyl isatins under ambient conditions result in isomerically
133 oles were prepared either from corresponding isatins using a three-step synthesis in an average overa
134       alpha-Aryl oxindoles are accessed from isatin via a two-step procedure involving a phospha-Broo
135                          The C-2 carbonyl of isatin was envisioned to react in the active site of HRV
136 (HRV-2) 3CP was solved and revealed that the isatin was situated in essentially the same conformation
137 N-tert-butanesulfinyl ketimines derived from isatins was a key step and provided diastereomeric adduc
138 en the structures of MAO-N proline and MAO-B-isatin were overlaid.
139 -(2(S)-(methoxymethyl)pyrrolidinyl)sulf onyl]isatin were synthesized in 140 min with 24% and 10% over
140 n-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatins were developed as a new group of nonradioactive
141 y in chiral BINOL-catalyzed allylboration of isatins were examined by DFT calculations.
142           A novel series of 2,3-dioxindoles (isatins) were designed that utilized a combination of pr
143  catalytic enantioselective allylboration of isatins with 2-allyl-1,3,2-dioxaborolane in the presence
144 H)-ones via acylation of various substituted isatins with readily available N-Boc-protected aminoacid

 
Page Top