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1  subsequently replicated to form a dicentric isochromosome.
2 unced in a microcell hybrid that received an isochromosome 11q derived from the donor copy of chromos
3 f adolescents and adults, most usually as an isochromosome 12p.
4 gains, such as trisomy 7 in glioblastoma and isochromosome 17q in medulloblastoma.
5                                              Isochromosome 17q, or i(17q), is one of the most frequen
6 loblastomas, including MYC amplification and isochromosome 17q, were easily detected.
7 esent in rhabdomyosarcomas, we identified an isochromosome 3q [i(3q)], which inhibits muscle differen
8         Genomic profiles confirmed recurrent isochromosome 7q (n = 6/9) without alterations at the SY
9 osomal aberrations associated with HSTCL are isochromosome 7q and trisomy 8, and most cases harbor mu
10                                              Isochromosome 7q was identified in two cases with cytoge
11 nian and jumping translocations, inversions, isochromosomes and small marker chromosomes, may also in
12                                        These isochromosomes are deficient for different terminal segm
13                                              Isochromosomes are mirror-imaged chromosomes with simult
14  genome instability, mechanisms that prevent isochromosomes are not well understood.
15 chromosomes (Robertsonian translocations and isochromosomes) are associated with an increased risk of
16 tion (H3K36me3), results in the formation of isochromosomes as well as isodicentric and acentric chro
17                                     Although isochromosomes commonly occur in cancer and developmenta
18 cific segmental aneuploidy, consisting of an isochromosome composed of the two left arms of chromosom
19 resence of two extra copies of Chr5L, on the isochromosome, conferred increased Flu(R) and that parti
20 gers distinct CA processes, revealing stable isochromosomes, coordinated segregation and amplificatio
21 hromosome losses, 18 partial deletions, nine isochromosomes, eight additions, and five translocations
22 , Rhp57 and the MRN complex to suppress both isochromosome formation and chromosome loss, in accordan
23 ults in a striking increase in break-induced isochromosome formation and very low levels of chromosom
24 me from the longest autosome by misdivision, isochromosome formation, and additional restructuring, w
25  To test the centromere misdivision model of isochromosome formation, we have defined the breakpoints
26  arise from a new break-induced mechanism of isochromosome formation.
27                                          The isochromosome forms around a single centromere flanked b
28           These data provide a mechanism for isochromosome generation and demonstrate that SETD2 and
29 cytogenetically monocentric and dicentric Xq isochromosomes (i(Xq)) from Turner syndrome probands, us
30 and, in particular, with the formation of an isochromosome [i(5L)] in the fungal opportunist Candida
31 DA-MB-157 and UACC-812) or of additional 20q isochromosome in MDA-MB-134.
32 cells contain 47 chromosomes due to an extra isochromosome of the long arm of chromosome 8, and the n
33 es), interstitial deletions (five cases), or isochromosome (one case).
34 o arms were connected via a centromere in an isochromosome or were present in two different chromosom
35 in more inversion translocations such as the isochromosomes seen in human tumors.
36 rug-resistant clinical isolates and can form isochromosome structures with breakpoints near the centr
37 y identified Robertsonian translocations and isochromosomes, UPD testing should be considered, especi
38  At medium to late passage, gain of 5p as an isochromosome was observed.
39 asmate pairing in meiosis, a series of novel isochromosomes was developed in hexaploid wheat (Triticu
40 ic metaphase I pairing of these asymmetrical isochromosomes was observed in plants with various doses
41              The two arms of an asymmetrical isochromosome were bound by a chiasma in only two of the
42 ntial dicentric translocations and dicentric isochromosomes were associated with cell cycle checkpoin
43 e z5AL telocentric chromosome and three z5AL isochromosomes were recovered.
44 cluding both Robertsonian translocations and isochromosomes, were studied prospectively to identify U
45 rongly associated with gain and loss of this isochromosome, which bears genes expressing the enzyme i