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1 eterozygous (GBA+/-) and homozygous (GBA+/+) isogenic lines.
2 ganoids (iCOs), including CRISPR-Cas9-edited isogenic lines.
3 duces the effort and time required to create isogenic lines.
4 Major QTLs were confirmed using near-isogenic lines.
5 e Al-tolerance phenotype to the derived near-isogenic lines.
6 ocation with DOG loci were validated by near isogenic lines.
7 on data for human individuals and Drosophila isogenic lines.
8 pe of HQE2 was validated by analysis of near isogenic lines.
9 e number variation in both sexes in a set of isogenic lines.
10 wild-caught cohort or in a set of 134 nearly isogenic lines.
11 her demonstrated in vivo using a pair of p53 isogenic lines.
12 d significantly different between the nearly isogenic lines.
16 were used: resistant (R) and susceptible (S) isogenic lines and a set of six natural accessions, thre
20 a non-diseased wild-type (WT) line (11 total isogenic lines), and examined gene expression and pathol
22 at flow cytometry measurements on cells from isogenic lines are consistent with those from population
23 oybean disease-resistance genes through near-isogenic line assays, followed by linkage analysis in F2
24 onse is not restricted to a particular trout isogenic line but expressed in multiple genetic backgrou
25 s identified in the semi-sterile barley near-isogenic line BW233 through fine mapping of the des12.w
28 GI and photoperiod is no longer observed in isogenic lines carrying either a photoperiod-insensitive
31 s produced higher shoot dry matter than near-isogenic lines carrying the susceptible allele suggestin
35 n with positional verification by using near-isogenic lines demonstrated that biosynthesis of two str
36 larvae and adults of Drosophila melanogaster isogenic lines derived from a natural population to extr
38 files of developing syncytia in soybean near-isogenic lines differing at Rhg1 (for resistance to Hete
39 detailed comparison was made between nearly isogenic lines differing for alleles at this locus to se
41 d both the in vitro and in vivo responses of isogenic lines differing only in the p53-transactivated
42 nt in vivo, xenografts were established from isogenic lines differing only in their p21 checkpoint st
43 al nature of the I locus using four pairs of isogenic lines differing with respect to alleles of the
44 ines generated from individuals with ALS and isogenic lines edited to harbor familial ALS mutations s
45 s, genome-wide association studies, and near-isogenic lines enabled the identification of terpene syn
46 is gene introgressed in desi and kabuli near-isogenic lines enhances the seed weight, yield, producti
48 ssion patterns of cells expressing no p53 to isogenic lines expressing the codon 248 Arg to Trp mutan
49 ontaining region of <200 kb was developed as isogenic lines for the qSD12 dormancy and non-dormancy a
50 genotypes (bwD and B3-09, a third-chromosome isogenic line from Beltsville, MD) was quantified by dou
51 tance assays, using ZmTps21 and Zmtps21 near-isogenic lines, further support the endogenous antifunga
55 they may affect fruit size, a pair of nearly isogenic lines has been subjected to detailed developmen
56 mapping was performed using two related near-isogenic lines in which a region located on soybean chro
57 arrying the Tau P301L mutation and generated isogenic lines in which p35 is replaced with noncleavabl
59 ifferential gene expression analysis of near-isogenic lines inoculated with Pgt at varying temperatur
60 1, a major QTL, has been confirmed in a near isogenic line (NIL) and maps to a new locus with effects
62 s identified, we subsequently created a near-isogenic line (NIL) pair for more detailed investigation
63 hCesA2-D(T) in developing fibers of one near-isogenic line (NIL) with higher fiber bundle strength ov
65 deficiency sensitive cultivar) and its near-isogenic line (NIL-23, P deficiency tolerant) for Pup1 Q
66 odifications were examined in a pair of near isogenic lines (NILs) (with and without Lr28 in the back
69 ed their interaction using a set of six near-isogenic lines (NILs) by metabolic, molecular and physio
73 Four Arabidopsis (Arabidopsis thaliana) near isogenic lines (NILs) differing in g were grown at ambie
75 ecombinant inbred lines and generated nearly isogenic lines (NILs) for two dimensional traits, pistil
76 ith recombinant inbred lines (RILs) and near-isogenic lines (NILs) identified several genomic regions
81 tive and reproductive development using near isogenic lines (NILs) that differ at the sun locus, and
82 Here, we developed and used a pair of near-isogenic lines (NILs) to characterize DNA methylome land
84 r starvation resistance, and we created near isogenic lines (NILs) to validate the effect of these QT
85 o parents were used to produce a set of near-isogenic lines (NILs) with small regions of introgressio
86 we characterized a panel of 1264 maize near-isogenic lines (NILs), developed from crosses between 18
87 of a grain-weight QTL, gw3.1, a set of near isogenic lines (NILs), was developed from an Oryza sativ
92 he time to flowering of inbred A619 and near-isogenic lines of bm2, bm1-bm2 and a segregating populat
94 ucleotide variation in the sequences from 20 isogenic lines of D. melanogaster and sequences from D.
97 Here, we used females from crosses among isogenic lines of Drosophila melanogaster, each mated to
98 Here, we confirm this prediction in young isogenic lines of hexaploid wheat carrying different dom
102 show that although the small-fruited nearly isogenic line produced smaller ovaries and fruit as expe
104 anosensory bristle number in six recombinant isogenic line (RIL) mapping populations, each of which w
105 present study, we generated a set of nearly isogenic lines segregating for the restorer region and m
106 h was also observed in genetically identical isogenic lines, strongly suggest a non-genetic mechanism
107 on of nematode and aphid resistances in near-isogenic lines suggested that these traits are tightly l
108 ith a reduction in SbMATE expression in near-isogenic lines, suggesting incomplete transfer of loci a
109 segregant analysis, our method produces near-isogenic lines that can be kept and reused indefinitely.
110 ld type (WT) and one mutant (MT) allele, but isogenic lines that carry only the WT (HCT116(WT)) or MT
111 s of the developing inflorescence using near-isogenic lines that contain either photoperiod-insensiti
112 es were also tested for virulence to 20 near-isogenic lines that differ for leaf rust resistance gene
113 s9) homology directed repair (HDR) to create isogenic lines that varied for the F187Y substitution.
114 of Al tolerance from the parents to the near-isogenic lines that was consistent across donor alleles,
115 alysis of two wheat (Triticum aestivum) near-isogenic lines, the glaucous line G-JM38 rich in cuticul
117 ing of F2 hybrids and fine-mapping in nearly isogenic lines to characterize the genomic regions under
118 nd apoptosis-and performed RNA sequencing on isogenic lines to identify differentially expressed gene
121 ungal leaf microbiomes of the resulting near-isogenic lines were compared with the microbiome of the
122 ns of X and third chromosome H/L recombinant isogenic lines were constructed in the homozygous low li
123 ations of backcrossing to M. nasutus, nearly isogenic lines were still >90% heterozygous at markers l
125 at the native field sites by comparing near-isogenic lines with alternate genotypes of CBF2 to their
127 ecreased accumulation of BLM in NBs, whereas isogenic lines with functional p53 exhibit normal accumu
128 t stem cell (iPSC)- derived macrophages from isogenic lines with homozygous PLCG2 knockout (Ko).
131 of wing shape were mapped, using recombinant isogenic lines, with transposable elements as markers.