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1 ne-diene to generate the target hexahydro-1H-isoindole.
2 ne, and cyanide, yielding a fluorescent beta-isoindole.
3 re determined to be substituted 1,3-dimethyl isoindoles.
4 tment with 2-(4-methyl-phenyl)sulphanyl-1 H -isoindole-1,3(2 H )-dione 6b.
5 (2,4-Difluoro-phenyl)-4,5,6,7-tetrafluoro-1H-isoindole-1,3(2H)-dione (CPS49) is a member of a recentl
6  Thalidomide, 2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione, has been shown to inhibit angio
7 on of o-halobenzoates produces 2-substituted isoindole-1,3-diones in good yields.
8 ydropyridazino[4',5':1,2]indolizino[3,4,5-ab]isoindole-1,4-dione 11.
9 (1E)-(4-ethoxyphenyl) methylene] amino}spiro[isoindole-1,9'-xanthen]-3(2H)-one (DEMAX) for Al(III) ch
10 -(4,5-dimethyl-2-furyl)methylene]amino}spiro[isoindole-1,9'-xanthen]-3(2H)-one (DMBD), was synthesize
11 d 14-15, benzo[1',2'-1,2]indolizino[3,4,5-ab]isoindoles 10, pyridazino[4',5':1,2]indolizino[3,4,5-ab]
12 10, pyridazino[4',5':1,2]indolizino[3,4,5-ab]isoindoles 12-13, and 2,3-hydropyridazino[4',5':1,2]indo
13                 They are indolizino[3,4,5-ab]isoindoles 2-9 and 14-15, benzo[1',2'-1,2]indolizino[3,4
14 igh as 10(4) cd/m(2) and indolizino[3,4,5-ab]isoindole 3 emits beautifully blue light.
15 (2), with 1-imino-4,7-bis(1-methylethoxy)-1H-isoindole-3-amine (4).
16 ines, azepanes, N-substituted 2,3-dihydro-1H-isoindoles, 4,5-dihydropyrazoles, pyrazolidines, and 1,2
17 ely substituted, partially saturated benzo[f]isoindole-4-carboxylic acids were synthesized by a new t
18 ch higher binding affinities than the parent isoindoles (5a-e), and whereas 7a-c were agonists in the
19                                    Using the isoindoles 5d-f as models, the stereochemistry and confo
20  catalyst to provide benzo[4,5]imidazo[2,1-a]isoindole acetamide.
21 lkyne ester provides benzo[4,5]imidazo[2,1-a]isoindole acetate exclusively.
22 chemistry of the ring junction of the benz[e]isoindole and a two-carbon spacer chain were optimal.
23 ss enables the one-pot formation of valuable isoindoles and 1,2-dihydrophathalazines.
24 ew of the reported synthetic methods towards isoindoles and related heteroaromatic systems over a tim
25  4-Cl-L-Thr, N-derivatization as fluorescent isoindoles, and HPLC separation compared with authentic
26 ovel class of 5-substituted 5H-imidazo[5,1-a]isoindoles are described as potent inhibitors of indolea
27                                     However, isoindoles are relatively unstable 10pi-heteroaromatic s
28 ing the utility of our methodology to obtain isoindoles as useful intermediates for the synthesis of
29 ine-fused isoindolines to benzoazepine-fused isoindole atropodiastereomers is investigated, revealing
30 ist, a novel series of 6-OMe hexahydrobenz[e]isoindoles attached to a bicyclic heterocyclic moiety vi
31 ificantly, spontaneous polymerization of the isoindole by-product generates colored derivatives, prov
32  (CN) creates an N-substituted 1-cyanobenz[f]isoindole (CBI) derivative, whose fluorescence can be se
33 ion for the chiral separation of cyanobenz[f]isoindole (CBI) derivatives of amino acids was developed
34                                              Isoindole containing BODIPY dyes are highly fluorescent
35 h was used to elaborate the 5H-imidazo[5,1-a]isoindole core and to improve potency and pharmacologica
36 ineered cysteine on the substrate to form an isoindole cross-linked product could not be performed in
37 First, the time-dependent degradation of the isoindole derivative L-serine-NDA-beta-mercaptoethanol w
38                                          The isoindole derivative was observed to react further with
39 was derivatized with OPA to form a UV-active isoindole derivative which was then detected at 230 nm.
40 nt lactam form of the originally fluorescent isoindole derivative.
41 effective method for synthesizing various 1H-isoindole derivatives in decent to excellent yields.
42  be measured by formation of the fluorescent isoindole derivatives of these compounds.
43 ed for the concise synthesis of hexahydro-1H-isoindole derivatives starting from phenacyl bromides.
44 -2-ones with N-substituted maleimides toward isoindole derivatives through the reaction sequence cycl
45 ne along with amperometric monitoring of the isoindole derivatives.
46 o access seleno-substituted isoquinoline and isoindole derivatives.
47 ng occurred at these positions to produce an isoindole fluorophore in the wild-type mu receptor.
48 anines, metal containing cyclic tetramers of isoindole, form coordination complexes with most element
49                              The kinetics of isoindole formation resulting from covalent binding of N
50              The fluorescence of the benzo[f]isoindole formed upon cross-linking of mu-opioid recepto
51 he synthesis of the unreported benzo-oxazino-isoindole framework by the iodide-catalyzed selenium-ass
52  easy multicomponent synthesis of polycyclic isoindoles from cyclic 1,3-dicarbonyls, aldehydes, isocy
53                         The formation of the isoindole goes to 85% completion and the overall recover
54                     Over the past few years, isoindoles have found wide application in materials scie
55  and biologically privileged succinimide and isoindole heteroarenes bearing benzothiadiazinedioxide m
56 e unimolecular degradation of the protonated isoindole in the absence of solvent or atmosphere, sugge
57  with three types of pharmacophores, imidazo-isoindole, indole-tetrazole, and indole-benzotriazole.
58 ctional calculations for indolizino[3,4,5-ab]isoindole (INI) derivatives.
59 ropisomers, Diels-Alder cycloaddition of the isoindole is achieved with complete facial selectivity,
60 lation cascade to obtain benzimidazole-fused isoindoles is reported.
61 When vinylogous carbamate is embedded in the isoindole moiety, a pyridoisoindole derivative was forme
62 ded conformation of the sulfonamide over the isoindole moiety.
63  cyclization, which ultimately results in an isoindole N-oxide product, is always kinetically and som
64           A palladium-catalyzed strategy for isoindole N-oxide ring construction by C-H functionaliza
65 d a radical pathway via iminoxyl radicals to isoindole N-oxides and an ionic mechanism leading to iso
66 s mechanistic insights into the diversity of isoindole N-oxides that can be produced through the phot
67  protocol is of general character, providing isoindole N-oxides with a variety of functional groups,
68 t represents the first reported formation of isoindole N-oxides.
69 cal shifts, we identified the products to be isoindole N-oxides.
70 p, presented the first reported formation of isoindole N-oxides.
71 on to afford spirocyclic benzimidazole-fused isoindole naphthalen-2-ones.
72 ansformations into spirocyclic isoindolines, isoindoles, or a polycyclic isoquinolinium salt have bee
73 cycloaddition reactions between pyrido[2,1-a]isoindole (PIS) and acetylene or ethylene derivatives.
74  highly specific requirements for the benz[e]isoindole portion and linker chain, a wide variety of tr
75 to afford naphthoxindoles E and pyrido[2,1-a]isoindole, respectively, in moderate to excellent yield.
76 annelation of the [1,2]oxazole moiety to the isoindole ring, producing derivatives with a wide substi
77 ol to form a more stable fluorescent methoxy-isoindole, shedding new light on the basis for enhanced
78  of 22 derivatives of the [1,2]oxazolo[5,4-e]isoindole system were synthesized through an efficient a
79  (BPI = 1,3-bis(2-(4-tert-butyl)pyridylimino)isoindole) to release methane and form (BPI)Pt(OTf) is r
80 A Ru(II)-catalyzed efficient synthesis of 1H-isoindoles via the cyclization of benzimidates with alke
81  a novel series of tricyclic hexahydrobenz[e]isoindoles was synthesized.
82 ropisomeric, bench-stable benzoazepine-fused isoindoles were synthesized via oxidation from isoindoli
83 enzo[a]cycl[3.2.2]azine (indolizino[3,4,5-ab]isoindole) with excellent enantio- and diastereoselectiv