ライフサイエンスコーパス: isomerization

1 opic investigations of the quantum nature of isomerization.

2 -opsin and retinal (the chromophore) without isomerization.

3 s to the crystal field splitting upon ligand isomerization.

4 nd the silica surface that prevent adsorbate isomerization.

5 e products by hydrogenation, allylation, and isomerization.

6 d heating and the concomitant conformational isomerization.

7 ys-255 is critical for substrate binding and isomerization.

8 hile FabA is primed for both dehydration and isomerization.

9 t of zeaxanthin, was low, suggesting E- to Z-isomerization.

10 lculations suggesting little possibility for isomerization.

11 cylated purines in DMSO as they are prone to isomerization.

12 ated with exquisite levels of retention over isomerization.

13 r rendering a probe insensitive to cis-trans isomerization.

14 calcium binding is followed by rate-limiting isomerization.

15 reversible color change as expected for the isomerization.

16 ctionalization on the kinetics of cis->trans isomerization.

17 luding subtle alterations such as side-chain isomerization.

18 k to D involves only one C13=C14 double-bond isomerization.

19 lation, disulfide-bond formation and proline isomerization.

20 ng and host-guest interactions on azobenzene isomerization.

21 orate the most attractive features of olefin isomerization.

22 eactions: DPA hydrogenation and (Z)-stilbene isomerization.

23 the extent of diol binding via photochemical isomerization.

24 concert with a base-promoted allylic alcohol isomerization.

25 d Fl-GluBP, glutamate binding is followed by isomerization.

26 ally-relevant RO(2) chemistry, including its isomerization.

27 the result of a key Ser(4)-Pro(5) cis-trans isomerization.

28 mechanism and kinetics of their photoinduced isomerization.

29 t provide in situ insights into photoinduced isomerizations.

30 However, owing to their high alkene isomerization activity and increased steric effects due

31 r dioxygenase mechanism along with potential isomerization activity that fine-tunes product profiling

32 rk apo-opsin noise than holo-pigment thermal isomerization activity.

33 Isomerization also perturbs recognition of peptide subst

34 ture of the TMC supporting ligand makes this isomerization an irreversible transformation, unlike for

35 Diene isomerization and [4 + 2] cycloaddition, common for conj

36 ization and subsequent, stereospecific allyl-isomerization and C-C bond-forming reductive elimination

37 The mechanism of the isomerization and dependence of the reaction routes on s

38 yzed simpler reactions with less double-bond isomerization and fewer cyclization steps.

39 insight into a tug-of-war between cis/trans isomerization and molecular chaperone activity.

40 lysis of FAAP20 mediated by prolyl cis-trans isomerization and phosphorylation at a consensus phospho

41 The high barrier of isomerization and propensity to adopt non-binding compet

42 t on-state involves trans-to-cis chromophore isomerization and proton transfer.

43 th solid-solid transformations and molecular isomerizations and bridges these disparate length scales

44 n of deamidation sites in proteomic studies, isomerization (and the isomeric products of deamidation)

45 kylation, jasminaldehyde synthesis, m-xylene isomerization, and cumene cracking) with better performa

46 on benchmarks for reaction thermochemistry, isomerization, and drug-like molecular torsions.

47 destabilized by the cis/trans backbone-amide isomerization, and few side-chains are capable of enforc

48 ormation, decarboxylation or esterification, isomerization, and lactamization, to furnish bicyclic 2-

49 s a critical step in chromophore attachment, isomerization, and stability.

50 ystallization of the liquid phase via Z-to-E isomerization, and the latent heat stored in the liquid

51 (vis-NIR) spectra, studies on their thermal isomerization, and theoretical calculations.

52 A sequential one-pot hydroalkylation-isomerization approach is also offered, giving access to

53 viding an alternative to traditional, direct isomerization approaches.

54 Deamidation and isomerization are known to be among the most prevalent c

55 Both face-flip and ring-walk isomerizations are identified through spin-saturation ex

56 rotary cycles based purely on photochemical isomerizations are rare.

57 Endergonic isomerizations are thermodynamically unfavored processes

58 operties of proline (ring pucker, cis/ trans isomerization) are introduced.

59 Our results reveal prolyl isomerization as a regulatory mechanism for SthK, and po

60 ounterion swap with the complex which favors isomerization as well as forming adducts with ancillary

61 ions that accumulate in long-lived proteins, isomerization at aspartate residues has been shown to be

62 10E8 heterogeneity being linked to cis/trans isomerization at two prolines within the YPP motif in th

63 Removal of the proline isomerization barrier through posttranslational truncati

64 Reducing the side-chain rotamer isomerization barriers in the all-atom force field is fo

65 ucker, cis/trans amide propensity, and amide isomerization barriers within a series of oxidation stat

66 , and the expected photochemical and thermal isomerization behavior was confirmed by NMR, UV/vis, and

67 The lipid-dependent PfMATE isomerization between OF and IF conformation is driven b

68 ericyclic reactions, bond dissociations, and isomerizations, but they have several characteristics re

69 Catalysis of proline isomerization by cyclophilin A lowers the energy barrier

70 ed by hydrometalation using [Pd-H] or [Ru-H] isomerization catalysts and driven by the formation of t

71 y of diimine complexes into efficient alkene isomerization catalysts, with catalyst loading as low as

72 Off-cycle olefin isomerization catalyzed by the same Co(-I) active specie

73 elective base- or ruthenium hydride-mediated isomerization/Claisen rearrangement cascade and a ring-c

74 vel control of physical properties caused by isomerizations, conformational motions, or chemical reac

75 tion scheme including enzymatic and chemical isomerization conversions.

76 In nonpolar solvents, slow and reversible isomerization corresponding to chemically-driven symmetr

77 lyzed C-H amination and Pd(0)(SOX) catalyzed isomerization cycles.

78 J measurements for an HJ-isomerization-deficient Cre mutant suggest that the appa

79 nzene molecules undergo reversible trans-cis isomerization, despite being close-packed; this surprisi

80 om a simple alpha,beta-unsaturated ester, an isomerization/dihydroxylation/lactonization sequence gav

81 We also discuss a Z-E isomerization during the alpha,beta-unsaturated amide fo

82 -step mechanism involving ligand binding and isomerization either of the apo or the ligand-bound bind

83 and, PPh(3), promotes vinyl- to allylrhodium isomerization en route to linear ketones.

84 ) (O(anti) )(TMC)(NCMe)](2+) (1) in MeCN, an isomerization facilitated by water and monitored most re

85 external oxidant and often suffered C=C bond isomerization for internal alkyl-substituted alkenes via

86 rmodynamic penalty imposed by differences in isomerization for the ATP and ADP growth at the barbed e

87 In some cases, a diene linkage isomerization from 3,4-eta(2) to 1,2-eta(2) could be eff

88 Isomerization from trans to cis was enhanced by both, co

89 -forbidden npai* state, the quantum yield of isomerization from trans- to cis-azobenzene is halved.

90 Molecular isomerization fundamentally involves quantum states boun

91 parameters for any cyclophilin-catalyzed W-P isomerization have been reported.

92 ytic performances but also to promote tandem isomerization-hydrosilylation reactions using internal a

93 -state (15)N NMR spectroscopy, the cis/trans isomerization in a two-dimensional (2-D) array of surfac

94 al and functional consequences of amino acid isomerization in alpha-crystallins using mass spectromet

95 eals the catalytic mechanism of EBP-mediated isomerization in cholesterol biosynthesis and how this p

96 rein, we show that interference with proline isomerization in HER2/EGFR overexpressing cells also ind

97 The observed rate constant for the N7/N9-isomerization in the adenine system (R = NH(2)) is k(obs

98 ,6-dichloro-1,4-benzoquinone suppressed this isomerization in the case of both Z- and E-PB and PI.

99 This is the first direct proof that isomerization in these alkyl ethylene intermediates is c

100 uctural change, especially the role of Pro32 isomerization in this reaction.

101 advantageous experimental platform to study isomerization in well-defined, atomically precise system

102 h fixational eye movements, followed by cone isomerizations in the retina.

103 A Gaussian beam self-traps when localized isomerization-induced contraction of the hydrogel and ex

104 The ranking of catalysts by (Z)-stilbene isomerization initial rates is Ni-Ga >> Ni-Sc > Ni-Lu >

105 The key element for selective isomerization is a tuned steric interaction between the

106 Sorbic acid (2,4-hexadienoic acid; HDA) isomerization is frequently used to probe triplet-state

107 Z to E isomerization is induced by irradiation with blue light,

108 Our findings indicate that the diamond core isomerization is likely a practical enzymatic strategy t

109 The energy barrier of P-isomerization is lower than that of olefination.

110 id derivatives by domino isoxazole-isoxazole isomerization is reported.

111 a-oxo-delta-azaproline, features rapid amide isomerization kinetics and isoenergetic amide bond geome

112 olid-solid transformation) with first order (isomerization-like) transformation kinetics.

113 s PTMs including oxidation, deamidation, and isomerization located in the complementarity-determining

114 wide range of (E/Z)-ratios by thermal (E/Z)-isomerization, lyotropic aggregation, and two different

115 The relevance of this isomerization may be expected for a series of nucleobase

116 1/2) (i.e., days) because of a change in the isomerization mechanism.

117 on class-II promoters via a recruitment and isomerization mechanism.

118 studies supports a mechanism in which alkene isomerization occurs by the allyl mechanism.

119 erization reaction: first, C13=C14 cis-trans isomerization occurs during S(2)-S(1) evolution in <100

120 Second, C15=N16 anti-syn isomerization occurs on the S(1)-S(0) evolution to the g

121 Transition metal-catalyzed isomerization of 1,1-disubstituted alkenes can serve as

122 olefin polymerization by triggering a rapid isomerization of 1-alkene monomers into internal olefins

123 A key photochemical valence isomerization of 3-prenyl-pyran-2-one produces both the

124 Fe(II)-catalyzed isomerization of 4-acyl-5-methoxy-/5-aminoisoxazoles (di

125 Fe(II)-catalyzed isomerization of 4-acyl-5-methoxyisoxazoles under milder

126 chlorides, generated by the Fe(II)-catalyzed isomerization of 5-chloroisoxazoles.

127 raviolet (UV) B (UVB, 280-310 nm) results in isomerization of 7-dehydrocholesterol to previtamin D th

128 electric field can catalyze the cis-to-trans isomerization of [3]cumulene derivatives in solution, in

129 We report that disease-associated mutations, isomerization of a critical proline, or alternative spli

130 otophysical properties from the photoinduced isomerization of a linear tetrapyrrole chromophore.

131 One reaction is the chromogenic isomerization of a naphthopyran mechanophore embedded in

132 Control of isomerization of a receptor bearing multiple light-switc

133 port a photocatalytic and diastereoselective isomerization of acyclic cinnamyl chlorides to strained

134 elaborated around transition metal-catalyzed isomerization of alkenes not only offer the inherent adv

135 tallic iron(I) complex is a catalyst for the isomerization of alkenes.

136 The asymmetric isomerization of alkyne to allene is the most efficient

137 It permits isomerization of alkynes with nonacidic alpha-C-H bonds

138 Both technologies induced E-to Z-isomerization of all-E-lutein and puffing also of all-E-

139 In the RPE, isomerization of all-trans-retinyl esters to 11-cis-reti

140 zed tandem process consisting of double bond isomerization of allyl ethers and amines and subsequent

141 red ruthenium(IV) complexes can catalyze the isomerization of allylic alcohols into saturated carbony

142 alcohols followed by an enantioselective Rh isomerization of allylic alcohols.

143 Similarly, isomerization of alphaBAsp-109 disrupted a vital salt br

144 Our results illustrate how isomerization of amino acid residues, which may seem to

145 ultiple pathways within the lens wherein the isomerization of aspartate residues in crystallin peptid

146 Here, we examined the impact of isomerization of aspartic acid or epimerization of serin

147 lative probability/kinetics of light-induced isomerization of azobenzene analogues in these host-gues

148 have employed molecular models to probe the isomerization of azobenzene guests within a Pd(II)-based

149 ound (22.1%) phenolics and induced trans-cis isomerization of beta-carotene.

150 Interestingly, isomerization of both acceptors to different degrees all

151 The catalytic isomerization of C-C double bonds is an indispensable ch

152 cis-trans isomerization of CTD prolines expands the scope of the c

153 port a general protocol for the light-driven isomerization of cyclic aliphatic alcohols to linear car

154 Aqueous-phase isomerization of d-glucose to d-fructose and l-sorbose i

155 Here, we show that the reversible isomerization of DHP can be stabilized upon confinement

156 corporated the NPN cofactor, and assayed the isomerization of different substrates guided by gene con

157 cterial proteins catalyzing the hydration or isomerization of double bonds in unsaturated fatty acids

158 isotope effects, it is established that the isomerization of epoxides into allylic alcohols catalyze

159 an their missing-linker counterparts for the isomerization of glucose to fructose.

160 to a long-lived dark state through cis-trans isomerization of its chromophore, as do most RSFPs.

161 Catalytic isomerization of linear to branched alkanes is a critica

162 were found to be effective in catalyzing the isomerization of maleic acid diesters to give fumaric ac

163 the water solvent catalyzed the trans-to-cis isomerization of MG at the air/liquid water interface re

164 In the remote MBL, unimolecular isomerization of MSP outpaces bimolecular chemistry lead

165 We take Pt/Beta catalyzed isomerization of n-heptane as the model system to explor

166 bited by serine epimerization and altered by isomerization of nearby alphaBAsp-62.

167 f ABCB-mediated auxin transport by cis-trans isomerization of peptidyl-prolyl bonds.

168 iridium complex to catalyze the concomitant isomerization of primary allylic alcohols and homoallylb

169 NMR spectroscopy shows that CypA catalyzes isomerization of proline 128 in the C-terminal domain of

170 e conformational changes including cis/trans isomerization of proline residues.

171 Catalysis of cis/trans isomerization of prolines is important for the activity

172 olyl isomerases (PPIases) catalyze cis/trans isomerization of prolines.

173 metal-ion-mediated cross-linking via thermal isomerization of spiropyran to its open, merocyanine for

174 arises from rapid reversible force-sensitive isomerization of STP to a merocyanine, which reacts rapi

175 ary for the cell to have a mechanism for the isomerization of such non-native disulfide bonds.

176 The isomerization of the (E)-azobenzene to its Z isomer enha

177 role of the promoter is to thereby catalyze isomerization of the agostic product of CO insertion to

178 tative muurolane biological precursor, redox isomerization of the allylic alcohol gave an epimeric mi

179 n be readily tuned by photoinduced trans-cis isomerization of the azobenzene unit.

180 However, cis-trans isomerization of the backbone tertiary amides may impair

181 linker in the resting state, indicating that isomerization of the beta11-12 linker is not merely a co

182 f an initial Birch reduction, followed by an isomerization of the C=C double bond, oxidative C=C clea

183 e of electron-donating alkyl groups leads to isomerization of the corresponding OBD to afford the sub

184 Light triggers the open- and closed-form isomerization of the diarylethene unit, which respective

185 nd or a putative iodine-catalyzed cis- trans isomerization of the employed olefins seem not to be an

186 ring-opening, Mo(CO)(6)-catalyzed cis-trans-isomerization of the enamine intermediate followed by 1,

187 uli, and on the other hand, the trans-to-cis isomerization of the ethylenic junctions is induced by v

188 , it is rapidly followed by an alkyne-allene isomerization of the excited branch.

189 ined model for P450 11B2 catalysis indicates isomerization of the intermediate to a lactol can explai

190 n ratio were prepared either by the previous isomerization of the linker or by postirradiation of the

191 rom blue-to-red upon selective light-induced isomerization of the photochromic acceptors to the fluor

192 t of the S-peptide reduces upon cis-to-trans isomerization of the photoswitch.

193 Cis to trans isomerization of the polymer was possible using Cu(I) sa

194 ch is evidenced also to take part in the Z/E isomerization of the product.

195 ion pathway requires a C13=C14, C15=N double-isomerization of the retinal chromophore, whereas the in

196 photochemical event upon light absorption is isomerization of the retinal chromophore.

197 verall effect of facilitating closed-to-open isomerization of the RNAP-promoter complex by compensati

198 Fe(NTf(2))(2)/Au(NTf(2)) tBuXPhos-catalyzed isomerization of the so-formed mixture of isoxazole/azir

199 Dynamic cis,trans-isomerization of the square planar complexes was observe

200 losterically modulated both by the cis/trans isomerization of the surrounding prolines that are CypA

201 f persistent radicals is followed by thermal isomerization of the symmetric C8b-C8c dimer to the C3c-

202 y reactions involving hydrogen atom assisted isomerization of thermodynamically less stable isomers o

203 erine 308, which recruits PIN1 for cis-trans isomerization of TRIM59, leading to TRIM59 binding to im

204 H/ACA class that are predicted to direct the isomerization of uridine residues to pseudouridine in sm

205 Trans amide bonds and fast cis- trans isomerization of Xaa-Pro bonds are crucial for the stabi

206 Cyclophilins catalyze the cis-trans isomerization of xaa-proline bonds, a rate-limiting step

207 hosphorylation triggers Pin1 binding to, and isomerization of, Kv4.2 at the pThr(607)-Pro motif, lead

208 sed on alternating photochemical and thermal isomerizations of overcrowded alkenes is well establishe

209 nfavorable steric interactions and competing isomerizations of tertiary alkyl metal intermediates.

210 To characterize the effect of isomerization on quaternary assembly, we utilized synthe

211 with prior functional data, suggest that the isomerization or flipping of the beta11-12 linker in the

212 ,6][5,6]-isomers and that some showed mutual isomerization or remained intact at room temperature.

213 alkyne hydroarylation and subsequent alkene isomerization or through a Pomeranz-Fritsch-type cycliza

214 We further show that cis/trans isomerization outpowers the holding activity of cyclophi

215 ynthesis, enzymatic hydrolysis and catalytic isomerization over 20%-MgO/SiO(2), converted 99.3% of la

216 atic hydrolysis of lactose and (2) catalytic isomerization over MgO/SiO(2).

217 biotransformation via clipping, deamidation, isomerization, oxidation, etc.

218 ivity between parallel stereoselective sugar isomerization pathways.

219 r switching between distinct reaction modes: isomerization-polymerization with high branching (0 equi

220 In many cases, these redox-neutral isomerizations proceed in opposition to a significant en

221 The reverse isomerization proceeds upon irradiation with blue light

222 photoisomerization whereas the cis-to-trans isomerization process of the chiral molecular switch can

223 Mechanical restriction of the E/Z isomerization process results in highly fluorescent comp

224 ylic positions was achieved by combining the isomerization process with Sharpless asymmetric dihydrox

225 ydrogen bonding has upon restricting the E/Z isomerization process, conformational energies of all an

226 Both the isomerization processes are efficient (Phi(ZE) ~ Phi(EZ)

227 understanding of bond-breaking processes and isomerization processes of highly reactive hydrocarbon i

228 al Bronsted acid is added next to engage the isomerization products into a stereocontrolled allylbora

229 n the presence of excess ethylene showed the isomerization rate is dependent on ethylene concentratio

230 We show that the observed isomerization rate is linearly dependent on LRT2 concent

231 Finally, although we found that the thermal isomerization rate of C6 HAT drastically increases on me

232 ilins that accelerate the intrinsically slow isomerization rate.

233 Glucose isomerization rates (per Ti, 373 K) are undetectable whe

234 Isomerization rates decrease to lower values (by ~20x) w

235 h with significantly faster amide cis/ trans isomerization rates.

236 d ligand is capable of accelerating the back-isomerization reaction by more than 6000-fold.

237 fferent configurations, suggesting an olefin isomerization reaction due to the decomposition of the c

238 The isomerization reaction is the key step for obtaining the

239 Optimization of the isomerization reaction mode led to a general set of cond

240 s reactive intermediate using the cage, each isomerization reaction proceeds to higher yield, which s

241 chains are continuously convoluted with the isomerization reaction, leading to a nonequilibrium proc

242 ity may not be relevant to the excited-state isomerization reaction.

243 ures a lower energy transition state for the isomerization reaction.

244 ns to overcome the thermodynamic limit of an isomerization reaction.

245 dride-enone intermediate is proposed for the isomerization reaction.

246 esulting in faster solvation relaxations and isomerization reaction.

247 tion to the S(2) state elicits a unique dual-isomerization reaction: first, C13=C14 cis-trans isomeri

248 Isomerization reactions are fundamental in biology.

249 Although a number of isomerization reactions exist, most methods require spec

250 Photoinduced isomerization reactions lie at the heart of many chemica

251 en-atom transfer from water to radicals, and isomerization reactions, as well as the development of a

252 ,2,3-triazol-4-ylidene type that undergo C-N isomerization reactions.

253 r compared to the rates of sn-2 cleavage and isomerization, respectively.

254 to pentannulated hydroquinolines through an isomerization/S(N)Ar in the same reaction pot at the ele

255 -phase molecules, eigenstates well above the isomerization saddle points have been characterized.

256 ctate through tandem ring-closing metathesis-isomerization sequence, undergoes a highly trans-diaster

257 This study highlights how proline isomerization should be considered a critical quality at

258 chanistic picture demonstrating an essential isomerization step in which the N-trans catalyst convert

259 A base-mediated isomerization step to an allenamide intermediate is the

260 hancement that occurred in the rate limiting isomerization step, the sensors described here all have

261 urring both in the glutamate binding and the isomerization steps.

262 .0]bicyclooctane core by an enantioselective isomerization/stereoselective [2+2]-cycloaddition strate

263 nt reaction conditions, including the use of isomerization suppressants, to minimize formation of the

264 metry (ERMS) analyses confirmed a successful isomerization suppression.

265 However, to observe the quantum nature of isomerization, systems in which transitions between the

266 that incoming monomers would need to undergo isomerization that would weaken the affinity and slow po

267 merase (LsLAI) for D-galactose to D-tagatose isomerization-that is limited by all three reaction para

268 o dissociate at the same rate as that of STP isomerization, the cascade limits crosslinking to overst

269 Instead these analogues restrict E/Z isomerization through intramolecular hydrogen bonding, r

270 n iron-hydride species which promotes olefin isomerization through sequential olefin insertion/beta-h

271 lative rates of ketene formation compared to isomerization to a seven-membered metallacycle, the most

272 -retinal produced by RGR and prevents its re-isomerization to all-trans-retinal.

273 drophobic environment accelerates cis- trans isomerization to an extent that thermally induced unfold

274 ehyde-vinyl bromide reductive coupling-redox isomerization to form branched ketones.

275 Iso-MTM undergoes a non-enzymatic isomerization to MTM catalyzed by Mg(2+) ions.

276 available pyridotriazoles undergo ring-chain isomerization to produce uniquely reactive alpha-diazoim

277 energy, with a barrierless downhill path to isomerization to the enol.

278 radiation of the E-isomer at 300 nm, partial isomerization to the Z-isomer (E/Z = 65:35 in the photos

279 e biosynthetic transformations, ranging from isomerizations to the stereospecific functionalization o

280 Photoinduced isomerization transforms the linear trans COE into a ben

281 on upon 530 nm irradiation and cis-to- trans isomerization upon 450 nm irradiation.

282 BINAM-derived bisurea catalysts undergo urea isomerization upon fluoride binding and form dynamically

283 Photochromic molecules undergo reversible isomerization upon irradiation with light at different w

284 econd-generation catalyst followed by olefin isomerization using a catalytic amount of RuCl(2)(PPh(3)

285 The Pd-catalyzed deconjugative isomerization was combined with a Cu-catalyzed beta-bory

286 No isomerization was detected in other organic solvents, fo

287 The N7/N9 isomerization was followed by (1)H NMR spectroscopy, unt

288 The isomerization was found to be nearly completely reversib

289 The catalytic isomerization was performed over MgO/SiO(2) with differe

290 energy barriers to ground- and excited-state isomerization, we evaluate the contributions of sterics

291 To investigate the consequences of aspartate isomerization, we investigated two alphaA crystallin pep

292 onstituents of bilirubin that undergo Z to E isomerization when excited with UV/blue light.

293 r 20-fold enhancement in binding upon E -> Z isomerization, which can be triggered with red light.

294 All new azo-PBIs showed photoinduced isomerization, which caused disaggregation and enhanceme

295 (such as aldol reactions, cyclizations, and isomerizations) will be considered at the end.

296 ible wavelengths (520 and 410 or 460 nm) for isomerization with high photoconversion efficiency.

297 significantly higher activity for catalytic isomerization with no loss in selectivity than current s

298 alking polymerization (1 equiv.), and alkene isomerization with no polymerization (>20 equiv.).

299 state, confirming structurally the change in isomerization with respect to HcReds' fluorescence state

300 dicates that accelerating the LRT2-catalyzed isomerization would not accelerate OsIAA degradation, wh