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1 , controlled trial of hypertonic (7%) versus isotonic (0.9%) saline inhaled twice daily for 48 weeks
6 esulted in a chimeric KCC that was devoid of isotonic activity, with intact swelling-activated transp
10 reduced NKCC1 activity in oocytes under both isotonic and hypertonic conditions to the same level as
13 vessels was performed with filter-sterilized isotonic and hypertonic solutions that contained glucose
16 he responses of cell cultures to significant isotonic and hypotonic challenges, and to hypertonic sal
22 us messenger produced in this nucleus during isotonic and short-term hypertonic conditions, is an exa
23 here are exclusive molecular determinants of isotonic and swelling-induced K(+)-Cl(-) cotransport in
29 ver, a channel that is active near -10 mV in isotonic Ba2+, originally identified as "N-type," corres
31 ells were subsequently exposed for 15 min to isotonic buffer (122 mM NaCl) also containing 100 mM EtO
32 ina was removed by exposure of the eyecup to isotonic buffer and wherever required, the retinal pigme
34 solution of mannitol, and pre-infusion of an isotonic buffer solution followed by infusion of nanopar
35 ter Pt disk microelectrodes at the nuclei in isotonic buffer solutions containing redox-active molecu
41 cerol-Ringer solution, its replacement by an isotonic Ca(2+)-Mg(2+) Ringer solution and cooling sharp
43 tudy, we illustrate how electroporation with isotonic calcium can achieve highly effective cancer cel
45 hemoglobin HbC or HbS+ gamma, replacement of isotonic Cl- media by hypotonic Cl- resulted in strong v
47 o independent methods (CO2 "conditioning" or isotonic Cl- substitution), are tested for CMC using two
49 (0.26 M) and 0.30 M sucrose are biologically isotonic conditions (275-299 mOsm/kg), and retention was
51 crom), under acidic (granule pH) and neutral isotonic conditions (extra-cytoplasmic pH), for GrB.SG i
52 es Ser-96 of human KCC3 is phosphorylated in isotonic conditions and becomes dephosphorylated during
53 e message of the gamma subunit was absent in isotonic conditions and increased with higher tonicity i
54 ysis demonstrating only minor staining under isotonic conditions and the substantial presence in chro
57 e membrane vesicles (MV) were isolated under isotonic conditions from human T lymphoblastoid cells MT
58 IMCD3 cells, nuclear export of TonEBP under isotonic conditions involves CRM-1 but under hypertonic
63 le mutant KCC3-S96A/T991A/T1048A activity in isotonic conditions was significantly higher, and it was
65 MDCK cells, blocks cell proliferation under isotonic conditions, and augments hypertonicity-induced
68 ly phosphorylated in plasma membrane KCC3 in isotonic conditions, suggesting that dephosphorylation i
72 By extruding Cl(-) from the neuron under isotonic conditions, this transporter maintains a low co
81 ng constitutive K(+)-Cl(-) cotransport under isotonic conditions; the other three KCCs are exclusivel
82 Our findings show diaphragm isometric and isotonic contractile abnormalities in a murine model of
83 r structural remodelling, fibre atrophy, and isotonic contractile dysfunction in the locomotor muscle
84 an age-related decline in the isometric and isotonic contractile function of permeabilized slow (MHC
87 ical ventilation on diaphragmatic isometric, isotonic contractile properties, or the expression of mu
88 ensitivity of tendon organs to steady-state, isotonic contractions of single and groups of in-series
89 ssive slowdown in shortening velocity during isotonic contractions was greatest in fast-twitch fibres
95 Saline made up a larger proportion of the isotonic crystalloid given in the saline group than in t
96 ic crystalloid), or hypertonic (3 mL/kg/hour isotonic crystalloid plus 1.2 mL/kg/hour 7.5% NaCl).
97 luid protocol groups: euvolemic (3 mLkg/hour isotonic crystalloid), hypervolemic (15 mL/kg/hour isoto
98 ic crystalloid), hypervolemic (15 mL/kg/hour isotonic crystalloid), or hypertonic (3 mL/kg/hour isoto
100 n deflation, and pigs were resuscitated with isotonic crystalloids and norepinephrine for 4.25 h.
103 he use of an atraumatic injection technique, isotonic diluent, a low-infusion pressure, and a small i
105 so decreased by 33-55% BAN firing induced by isotonic distension of the bladder at 10-40 cmH(2)O pres
106 meters), and microbiological safety of a new isotonic drink made of lemon and maqui berry over a comm
108 ters were affected by the heat, although the isotonic drinks remained with attractive red colour duri
110 in colorectal tissue, whereas hypertonic and isotonic enemas provided markedly reduced drug retention
111 essing clones acidify quite extensively upon isotonic exchange of Cl- and then rapidly alkalinize upo
112 pletely inhibited when larvae are wounded in isotonic external media, suggesting that osmotic gradien
113 ely 3000 kDa) was predominantly extracted in isotonic Extract A (70.1 +/- 6.0%) and PBS (37.7 +/- 3.2
115 asound-guided percutaneous amnioinfusions of isotonic fluid before 26 weeks' gestation, with frequenc
116 ed the therapeutic potential of hydrodynamic isotonic fluid delivery (HIFD) to the left renal vein 24
118 to receive commercially available plasmalike isotonic fluid therapy (140 mmol/L of sodium and 5 mmol/
119 more common in children receiving plasmalike isotonic fluid therapy (61 of 308 patients [20%]) compar
121 el and water cotransport could contribute to isotonic fluid transport across the intestinal brush bor
129 n facilitates transfer of OHC displacements (isotonic forces) for cochlear amplification and neural e
130 followed midmorning by a 90-min infusion of isotonic glucose (15 g, 235 kJ) or saline to the duodenu
132 lutions had no vasoactivity in aortic rings, isotonic glucose produced a selective, insidious, and ti
134 vel at 48 hours was 139.9 (2.7) mEq/L in the isotonic group and 139.6 (2.6) mEq/L in the hypotonic gr
136 ding stresses linked to the penetration into isotonic host tissues and a possible rearrangement of th
141 ee fractionation techniques, NaBr gradients, isotonic iodixanol, and sucrose gradient centrifugation.
143 l practice guideline recommending the use of isotonic IVF for patients aged 28 days to 18 years witho
144 extraluminal bath using three paradigms: (1) isotonic K(+) (K(iso)) where increases in K(+) were offs
146 Inhibition of both isometric as well as isotonic kinetics demonstrates that viscous resistance t
149 le swimmers performed 25 m sprints with five isotonic loads (1-2-3-4-5 kg for females; 1-3-5-7-9 kg f
151 leukocytes where the cells are exposed to an isotonic lysis buffer for less than 40 s, after which th
152 Our study results support the notion that isotonic maintenance fluid administration is safe in gen
153 llular ion depletion by local perfusion with isotonic mannitol failed to reduce the gating charge fur
154 t primary astrocyte cultures were exposed to isotonic media (122 mM NaCl) for 15 min, followed by 45-
155 Na+ currents were small when cells were in isotonic media but could be increased by inhibiting cons
156 study demonstrated that Chen Medium (CM), an isotonic media enriched with nonlactate-generating high-
159 ion in plasma membrane in potassium-depleted isotonic medium (0.5 or 2 mEq/L KCl) versus cytoplasmic
160 urs; afterward, the medium was replaced with isotonic medium (285+/-4 mOsm) containing 40 mM galactos
165 pression was elevated, whereas the return to isotonic medium reduced AQP1 expression in a time-depend
172 nd ipratropium bromide with either 2.5 mL of isotonic MgSO(4) (250 mmol/L; 151 mg per dose; MgSO(4) g
175 re, we performed intracortical injections of isotonic MnCl(2), comparisons of preinjection and postin
176 first to formally apply a tool that uses an isotonic (monotonic) regression approach to this area of
179 Darby canine kidney cells were treated under isotonic or hypertonic conditions with the nitric oxide
180 sthesia only, anesthesia 1 h prior to either isotonic or hypertonic saline injection or no anesthesia
181 r 20% of albumin) or crystalloids (n = 1443; isotonic or hypertonic saline or Ringer lactate solution
183 he dependence of the transported osmolarity (isotonic or hypertonic) on channel radius, length, and o
187 ss in case of obesity, engagement in regular isotonic physical activity, reduced sodium diet (<100 mm
188 arly, lactate that was dissolved in a low-pH isotonic physiologic salt solution produced significant
189 lation of spherical and elongated virions in isotonic (physiologic salt concentration) and hypertonic
191 framework based on parallel linear (SAM) and isotonic regression (PIR) methods identified 95 and 53 p
193 pool adjacent violators algorithm (PAVA) for isotonic regression and inherits its linear-time computa
196 aluating the trend of spatial patterns using isotonic regression, we show that in yeast and prokaryot
198 n of NHE-1 with pharmacological agents or by isotonic replacement of sodium in the perfusate with cho
199 by pharmacological inhibitors of NHE-1 or by isotonic replacement of sodium, closely linking the prot
200 ith Ricrolin TE (n = 35) or epi-off CXL with isotonic riboflavin (n = 26) in 1 academic treatment cen
201 cross-linking efficacy or safety, given that isotonic riboflavin solution is viscous and each install
203 riuretic response to intravenous infusion of isotonic saline (2% body weight, given over 5 min).
206 on with hypertonic saline (HS) compared with isotonic saline (IS) in infants with CF, including LCI a
207 (ie, improvement) in LCI(2.5) compared with isotonic saline (mean treatment effect -0.63 LCI(2.5) un
208 151 mg per dose; MgSO(4) group) or 2.5 mL of isotonic saline (placebo group) on three occasions at 20
209 , is the culprit in dilutional hyponatremia, isotonic saline administration may further depress the s
211 balloon-tipped catheter, an aortic flush of isotonic saline at 2 degrees C (at a rate of 1 L/min), u
212 s at high risk were hydrated with 1000 mL of isotonic saline before and after contrast material expos
214 e of inhaled hypertonic saline compared with isotonic saline did not reduce the rate of pulmonary exa
215 ar electrosurgery include the ability to use isotonic saline during surgery, reduced blood loss and l
218 = -2.46 to 0.06), and remained stable in the isotonic saline group (n = 13) at 0.81 (95% CI = -0.40 t
219 adverse events and eight participants in the isotonic saline group had nine serious adverse events.
220 hypertonic saline group vs three [4%] in the isotonic saline group), gastrostomy tube placement or ru
223 eived a median (range) 3230 mL (390-7300) of isotonic saline in the first 6 hours and 5450 mL (710-13
224 fic to sweet taste because neither water nor isotonic saline infusion affected forepaw escape latenci
225 ete a short-term sodium load (5% body weight isotonic saline infusion over 30 minutes) and a long-ter
228 lity to inhaled 7% hypertonic saline or 0.9% isotonic saline nebulised twice daily (for no more than
229 tative analysis revealed that treatment with isotonic saline or 200 ng senktide resulted in the diffe
230 pattern was not shown by rats that received isotonic saline or systemic 2-deoxy-d-glucose (a glucose
232 214 subjects during the "placebo" infusion (isotonic saline solution) immediately preceding the lact
234 traperitoneal injection of either ethanol or isotonic saline using c-Fos expression as a marker of ne
235 saccharide (3 mg/kg intravenously, n = 9) or isotonic saline vehicle (control, n = 5) administration,
241 e stability of Na(2)[(99m)Tc(CO)(3)(NTA)] in isotonic saline was assessed for 24 h and was further ev
242 n commenced for 3 minutes, and dantrolene or isotonic saline was infused at the onset of cardiopulmon
243 nd 77% of SON neurons, respectively, whereas isotonic saline with anesthesia and anesthesia alone res
244 rosemide (5 mg) or vehicle solution (sterile isotonic saline) and sacrificed either 1.75 h (short-sur
247 s infusion of 1.5mug/min of CGRP or placebo (isotonic saline) over 20 minutes on two separate experim
248 volume of vehicle (30% Solutol HS15 and 70% isotonic saline, 0.37 ml/kg, n=5) or saline (0.37 ml/kg,
249 eceive either rhEPO (3000 IU/kg) or placebo (isotonic saline, 0.9%) intravenously within 3 hours, at
250 e randomized to either fluid loading (n = 8, isotonic saline, 1 L/hr for 2 hr) or diuretic treatment
251 nd the control group (n = 163) received 0.9% isotonic saline, nebulized twice daily for 48 weeks.
252 (18)F-TFB was eluted from the cartridge with isotonic saline, passing through 3 neutral alumina cartr
261 ng epithelial sodium channel blocker (P308); isotonic saline; or no treatment, using a nebuliser inte
262 7 RTNs formed stable particles of <200 nm in isotonic salt buffers, compared with 4-microm particles
265 is method to mice that were dialyzed with an isotonic salt solution under quiescent conditions for 1
266 e pH is slightly reduced from 7.4 to 6.6, in isotonic salt solutions that simulate the acidic extrace
267 hypertonic challenge monotonically around an isotonic "set point" and that these responses depend on
269 consequence of the KCl loss and concomitant isotonic shrinkage caused by increased [Ca2+]i as it per
271 patients with nonoliguric renal failure and isotonic sodium bicarbonate infusions to prevent radioco
272 efit of using sodium bicarbonate rather than isotonic sodium chloride for preventing contrast-associa
273 ether hydration with bicarbonate rather than isotonic sodium chloride reduces the risk of contrast-as
274 otide) infusion (150 mg/h); (3) placebo with isotonic sodium chloride solution (saline) infusion (fas
276 locker furosemide produced cell shrinkage in isotonic solution and blocked cell swelling normally ind
279 tion of a relatively large volume (10 ml) of isotonic solution containing a radiolabeled protein that
286 : Secondary analysis of patients from SMART (Isotonic Solutions and Major Adverse Renal Events Trial)
290 d against 10, 20, 30, 50 or 100 mM NaCl made isotonic to 154 mM NaCl by supplementing with sorbitol w
292 ansport is abrogated by calyculin A, whereas isotonic transport mediated by KCC chimeras and KCC2 is
295 abeculae from the rat heart to determine the isotonic velocity transient following a stepwise reducti
296 erimental model to induce uniform and stable isotonic volume changes in RBC populations from healthy
298 cological agents were effective in producing isotonic volume responses in human airway epithelia but
299 theses, "hypotonic [low salt]/defensin" and "isotonic volume transport/mucus clearance," attempt to l
300 the speed of the early rapid shortening (the isotonic working stroke) increase by reducing T from app