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1                                          The isotopic abundance measurements for (235)U and (238)U in
2 age precision of 6.7 x 10(-6) for fractional isotopic abundance retrievals in 1 s.
3 d samples of alpha(1)-antitrypsin at natural isotopic abundance to investigate the consequences of di
4  isotopic reference materials, each measured isotopic abundance value could be directly compared to a
5                                      Natural isotopic abundances of mixtures of compounds containing
6  bodies to fully melted iron meteorites with isotopic affinities to carbonaceous chondrites.
7 l spread of savannas broadly correspond with isotopic age estimates and encompass the entire hominin
8 astern Italy via spatially resolved chemical/isotopic analyses and histomorphometry of deciduous teet
9            Atom probe tomography (APT)-based isotopic analyses are becoming increasingly attractive f
10                             Moreover, stable isotopic analyses indicated that eels are likely one of
11 y studied using various approaches including isotopic analyses of fossil collagen.
12 rbitrap mass spectrometer to perform uranium isotopic analyses of solution residues on cotton swipes.
13  demonstrate accurate and repeatable uranium isotopic analyses, via atom probe mass spectrometry, on
14            The combination of seabird tissue isotopic analysis and spatial tracking helps in tracing
15                        Combined chemical and isotopic analysis of ceramic sherds (n = 125) from Pasto
16                                    Magnesium isotopic analysis of cerebrospinal fluid (CSF) is a pote
17 l method was developed for ultrasensitive Mg isotopic analysis of CSF microsamples via multicollector
18  environments has depended heavily on carbon isotopic analysis of fossil bones and palaeosols.
19 a-mass spectrometry (ns-LA-MC-ICP-MS) for Fe isotopic analysis of glassy cosmic spherules.
20                          Using molecular and isotopic analysis of lipids from pottery, here we invest
21                                              Isotopic analysis via pneumatic nebulization MC-ICP-MS,
22                            Ultrasensitive Mg isotopic analysis was carried out for CSF from hydroceph
23 method for speciated NH(4)(+) collection for isotopic analysis with important implications for furthe
24  to validate the results obtained by in situ isotopic analysis, and good agreement was achieved betwe
25                                  For in situ isotopic analysis, the precision of the delta(56)Fe valu
26 es and sinks, which can be supported through isotopic analysis.
27 hese initial provisions, new features of the isotopic anatomy of mineral ions can now be explored wit
28  water quality monitoring compared solely to isotopic and chemical data in areas with microbial metha
29 ommunity as to the reliability of atom probe isotopic and elemental analyses.
30 for wine authenticity control by means of Sr isotopic and elemental composition.
31                   We show that the He and Ne isotopic and elemental signatures of the Yellowstone gas
32                                              Isotopic and functional morphological analyses of early
33                                              Isotopic and growth time series revealed an evolving phy
34 ons were found in only one aquifer, and both isotopic and microbial data support a microbial origin.
35                                       Recent isotopic and paleomagnetic data point to a possible conn
36       Here, we report detailed morphometric, isotopic, and genetic analyses of Zhur that reveal detai
37 e infusion of molecular biological, genomic, isotopic, and geochemical modeling approaches have led t
38 d isotope composition of the so-called DUPAL isotopic anomaly in the Indian MORB-type mantle.
39 age authenticity, chemical, biomolecular and isotopic approaches could be applied depending on the le
40 ate the potential of emerging triple-element isotopic approaches including chlorine to carbon and hyd
41 lore the potential of targeted molecular and isotopic biomarker analysis on polyester resin-impregnat
42 overn the marine sulfur cycle and associated isotopic change is critical to understanding how climate
43 nt global reservoir for mercury (Hg) and its isotopic characterization is important to understand sou
44  degrees C, the PAS can be used for reliable isotopic characterization of GEM (+/-0.3 per mille for M
45 , we report the discovery and the petrologic-isotopic characterization of UH154-11, a ferroan trachyb
46 t studies, predictive metabolic analyses and isotopic characterization, provide a collective strategy
47  and viewing isotopic envelope and extracted isotopic chromatogram features.
48 intrinsic WUE (iWUE) from gas exchange and C isotopic composition (delta(13) C) differ due to an inte
49           Our results show that water oxygen isotopic composition (delta(18)O(water)) rather than lak
50                                       The Pb isotopic composition analyses combined with a case-contr
51                                       The Pb isotopic composition analysis suggested clear anthropoge
52 ry experiments to assess the preservation of isotopic composition during sampling of gaseous elementa
53 ctions of greenness and foliar nutrition and isotopic composition from herbarium samples.
54 al parameters, Cu and Zn concentrations, and isotopic composition in solution in the presence of matu
55 olution measurements of wood anatomy and the isotopic composition in tree-rings have the potential to
56  out using molecules that differ only in the isotopic composition of a phenyl group positioned remote
57               Here we use the neodymium (Nd) isotopic composition of absolute-dated cold-water coral
58 ) and lumen area (LA), along with the oxygen isotopic composition of alpha-cellulose (delta(18) O(cel
59                                       Stable isotopic composition of atmospheric nitrate (nitric acid
60 ate-water system, at equilibrium, the oxygen isotopic composition of carbonate is dependent not only
61 throughout at a level that is similar to the isotopic composition of Fe(II)(aq).
62 irm the ability to record differences in the isotopic composition of GEM (i) with distance from point
63  not only on the temperature but also on the isotopic composition of host water in which the carbonat
64 ern China to evaluate controls on the oxygen isotopic composition of lacustrine authigenic carbonates
65  has been developed to reliably quantify the isotopic composition of liquid water, requiring only imm
66 (water), and is ultimately controlled by the isotopic composition of local precipitation (delta(18)O(
67 al sulfur cycle are inferred from the sulfur isotopic composition of marine barite.
68  grown pyrites, we show that the triple iron isotopic composition of Neoarchean-Paleoproterozoic pyri
69 d understanding of processes controlling the isotopic composition of precipitation.
70                                     Although isotopic composition of reef carbonate material can be u
71 we report precise measurements of the stable isotopic composition of ruthenium captured in air filter
72 namics of sea surface temperature and oxygen isotopic composition of seawater from 1982 to 2016, base
73                         We also measured the isotopic composition of soil microbial biomass and the r
74                                       The Mg isotopic composition of the CSF from hydrocephalus patie
75                            The elemental and isotopic composition of their skeletons is frequently us
76 y associated with two model assumptions (the isotopic composition of water at the sites of CO(2)-wate
77 LSC lavas have a slightly more radiogenic Hf isotopic composition than VFR lavas.
78                        Here, we used mercury isotopic composition to assess the dietary origin of MeH
79 atite chondrite (EC) meteorites have similar isotopic composition to terrestrial rocks and thus may b
80     The response in metal concentrations and isotopic composition to variations in photosynthetic act
81 f the 2017 nuclear release has a non-natural isotopic composition.
82                      Its chemical and oxygen isotopic compositions are consistent with very-low-degre
83 e ratios around 5.3% and (13)C and D methane isotopic compositions around -40 and -240 per mille, res
84          Finally, stable carbon and nitrogen isotopic compositions determined from both mat samples s
85 wed that the water-metabolism-derived triple-isotopic compositions due to impaired water absorption i
86 on are the dominant mechanisms in regulating isotopic compositions in aerobic and anaerobic condition
87                     EC hydrogen and nitrogen isotopic compositions match those of Earth's mantle, so
88 ge of the distributions and enantiomeric and isotopic compositions of amino acids and polyols found i
89                                      Mercury isotopic compositions of amphipods and snailfish from de
90         We show that the distinct molybdenum isotopic compositions of CAIs cover almost the entire co
91                     The present-day nitrogen isotopic compositions of Earth's surficial ((15)N-enrich
92 tical method to measure the N-elemental and -isotopic compositions of experimental run products compo
93                                     Yet, the isotopic compositions of lithophile elements (Sr, Nd, Hf
94 t unexpected, large mass-independent sulphur isotopic compositions of pyrite with Delta(33)S of up to
95      By comparing our results with ruthenium isotopic compositions of spent nuclear fuels, we show th
96                            The molecular and isotopic compositions of such residues can be used to re
97               Extrapolation of the Nd and Hf isotopic compositions of the kimberlite source to the ag
98 tain two Cl-bearing components with elevated isotopic compositions relative to the bulk-Earth value o
99 -spatial resolution techniques to obtain C-N isotopic compositions, chemical, and structural informat
100  in biosynthetic/degradation and geochemical isotopic compound studies.
101                                  While these isotopic compounds exhibit identical crystal structures
102 rge isotopic range, comparable to the annual isotopic cycle.
103 e we use new and published carbon and oxygen isotopic data (n = 999) taken from large-bodied fossil m
104                                              Isotopic data could clearly differentiate between sample
105     Here, we report high-precision noble gas isotopic data from volcanic gases emanating from, in and
106                            We compared these isotopic data to dogs across the Northwest Coast, which
107 mbination of zooarchaeological, genetic, and isotopic data, provides proxy evidence for a fundamental
108 ten records as well as ceramic, textile, and isotopic data.
109 hich is confirmed by our oxygen and chromium isotopic data.
110 as more sensitive to the distribution of the isotopic data.
111 chored in numerical time by means of a radio-isotopic date, obtained from a bentonite layer interbedd
112                                        Radio-isotopic dates over this interval in the Karoo Basin wer
113                                       Stable isotopic (delta(13) C and delta(15) N), elemental (C and
114  important implications for the chemical and isotopic determination of provenance for future studies.
115 and pNO(3)(-) for off-line concentration and isotopic determination was tested using both laboratory
116 gin of neon in the mantle, which exhibits an isotopic dichotomy between solar plume and chondritic MO
117                             Otherwise, no Ru isotopic difference relative to the modern mantle would
118 aprids) across the Mediterranean reflect the isotopic differences observed in rainfall (but delta(18)
119 idation and nitration free adducts by stable isotopic dilution analysis liquid chromatography-tandem
120                            We carried out an isotopic dilution assay to quantify the plant-available
121  and selenometabolites by species unspecific isotopic dilution ICP-MS, with unequivocal identificatio
122 etry with de novo-generated standards and an isotopic dilution strategy and will fill a gap in our un
123 nd K), the plant-available pools measured by isotopic dilution were greater than the conventional exc
124 heoretical predictions and evidence that the isotopic disequilibrium commonly observed in speleothems
125                           Computation of the isotopic distribution of compounds is crucial to applica
126 try, but, as thermal maturity increases, the isotopic distribution of these species approaches thermo
127               In this study, we evaluate the isotopic distributions of z' ions in protein top-down MA
128 ing the fragment ion patterns of overlapping isotopic distributions.
129   We find only minor differences between the isotopic ecology of both these taxa.
130 pin qubits, and highlights the importance of isotopic enrichment of device substrates for the realiza
131       Iron status indicators and stable iron isotopic enrichment were measured in maternal blood, umb
132 nstrate unprecedented nanoscale mapping of U isotopic enrichment with high sensitivity across various
133                                              Isotopic enrichments of plasma oxalate, glycolate, and g
134  for capturing, editing, saving, and viewing isotopic envelope and extracted isotopic chromatogram fe
135 a analysis, which groups spectral peaks into isotopic envelopes and extracts monoisotopic masses of p
136 al neural network-based model for evaluating isotopic envelopes.
137 ethane) exhibit a separate pattern of mutual isotopic equilibrium (generally at reservoir conditions)
138 te rostrum implies that it precipitated near isotopic equilibrium and confirms the warmer-than-presen
139   In 100 degrees to 120 degrees C sediments, isotopic evidence and increased cell concentrations demo
140                                   We present isotopic evidence for native forest being of higher qual
141  In this study, we report on detailed carbon isotopic evidence from the hominin fossil record of the
142               In a phylogenetic context, the isotopic evidence implies that woodcutting and consumpti
143                                              Isotopic evidence indicates a diet of woody plants and f
144  membrane antigen (PSMA) that are labeled by isotopic exchange (IE).
145 uid, contrary to what is expected in case of isotopic exchange between minerals and H(2)O-fluids.
146 he Bronsted acid proton is not necessary for isotopic exchange into the framework.
147                               Stoichiometric isotopic experiments and the kinetic analysis of the tra
148 FTICR-MS enabled the simultaneous capture of isotopic fine structures (IFSs) for 47 known and 11 unkn
149 show that the release is consistent with the isotopic fingerprints of a civilian Russian water-water
150 c arc(3), we studied boron trace element and isotopic fingerprints of melt inclusions.
151 or estimating past pCO(2), the stable carbon isotopic fractionation associated with photosynthesis (E
152 ool with important potential for contrasting isotopic fractionation at the diel scale.
153               The processes governing the Hg isotopic fractionation differ across sites depending on
154  the effect of U(VI) reduction kinetics on U isotopic fractionation during U(VI) reduction by a novel
155 esting that CO(2) exerts a strong control on isotopic fractionation in natural phytoplankton communit
156                                     Using an isotopic fractionation model informed by these data, we
157               In this study, we compared the isotopic fractionation of copper in the GI tract of mice
158 oil pH strongly affected the direction of Zn isotopic fractionation.
159 ORM-SSB) to efficiently correct instrumental isotopic fractionation/mass bias and matrix effects.
160 y understood, we experimentally determined N-isotopic fractionations during metal-silicate partitioni
161 thod to disentangle the competing effects of isotopic fractionations of water during respiration in h
162 t mass spectrometry (EUV TOF) to map uranium isotopic heterogeneity at the nanoscale (<=100 nm).
163          EUV TOF's ability to assess and map isotopic heterogeneity at the nanoscale makes it a promi
164                                We use stable isotopic indicators of animal dietary and mobility patte
165 atios along a single ablation line indicated isotopic inhomogeneity exceeding 1 per mille in some mic
166 eted quantification of the metabolites using isotopic internal standards in the exploratory cohort as
167 ticity marker, and using curcumin as the non-isotopic isobaric internal standard.
168  pair of MS/MS spectra that differ due to an isotopic label can assist in identifying the relevant m/
169 oice of which metabolite to enrich and which isotopic label to use is highly context dependent, but (
170 tabolism of seven Brucella species by stable isotopic labeling and genetics.
171 diate in both CO(2)RR and CORR, via combined isotopic labeling and in situ spectroscopic investigatio
172 ced multiplexing strategy combined precursor isotopic labeling and isobaric tagging (cPILOT) for high
173                           Combined precursor isotopic labeling and isobaric tagging (cPILOT) is an en
174 ial aspect mostly performed with the help of isotopic labeling and site-directed mutagenesis, and com
175                                              Isotopic labeling experiments and the computed reaction
176 alyst characterization, kinetic studies, and isotopic labeling experiments unveil that molecular O(2)
177                                              Isotopic labeling experiments using U(13)C-glucose showe
178                              (13)C and (14)C isotopic labeling experiments were used together with co
179                                        Using isotopic labeling experiments, we found that activated b
180 advantages of segmental (or domain-specific) isotopic labeling for NMR, or deuteration for neutron sc
181 variation of the reaction conditions and the isotopic labeling of methane by deuterium allow for an u
182 ased substrate analysis using terminal amine isotopic labeling of substrates (TAILS).
183 sed on ball-milling, for the (17)O and (18)O isotopic labeling of two key fatty acids which are widel
184               Our new rate, selectivity, and isotopic labeling results from ECH reactions confirm tha
185 degrees C and analyzed by ESI-qTOF-MS/MS and isotopic labeling technique.
186                 Here, we apply site-specific isotopic labeling to obtain high-resolution NMR data on
187                  Here, both gas exchange and isotopic labeling were carried out on sunflower leaves,
188 d after an oral fructose/glucose bolus using isotopic labeling with 1-(13) C(1) -acetate intravenous
189 in N2a neuroblastoma cells by dynamic stable isotopic labeling with amino acids in cell culture (dSIL
190           Kinetic and thermodynamic studies, isotopic labeling, and DFT calculations using energetic
191 ectron paramagnetic resonance (EPR) studies, isotopic labeling, and other control experiments suggest
192 ed by various experimental probes, including isotopic labeling, intermediate validation, and kinetic
193 e particles (VLPs), facilitated by segmental isotopic labeling, that provide information about effect
194                                              Isotopic-labeling experiments have been valuable to moni
195 A-seq transcriptomics, proteomics and stable isotopic labelling coupled with mass spectrometry-based
196 ese pyridines are proposed, and confirmed by isotopic labelling experiments.
197 ned from spectroscopy combined with in vitro isotopic labelling of this cluster using chemical synthe
198 (1) H NMR spectroscopic kinetic studies, H/D isotopic labelling, and X-ray crystallography.
199                           Combining FEMS and isotopic labelling, we showed that the oxygen in the as-
200  in the visible region, further confirmed by isotopic labelling.
201                        The identification of isotopic labels by conventional macroscopic techniques l
202 hosphide and boron arsenide as the identical isotopic mass disorder becomes increasingly invisible to
203 4) , as shown by product analysis and (13) C isotopic measurement.
204 ditions, as reconstructed from stable carbon isotopic measurements across a global network of 103 abs
205                                              Isotopic measurements are often relied upon as indicator
206                       High-precision silicon isotopic measurements of 7 AOAs from weakly metamorphose
207                  Through high-precision iron isotopic measurements of Archean-Paleoproterozoic sedime
208                          We present ice core isotopic measurements of methane (Delta(14)C, delta(13)C
209                                          The isotopic measurements were -28.3 to -26.9 for Greek samp
210 ons of speciated HNO(3(g)) and pNO(3)(-) for isotopic measurements would best utilize the NaCl soluti
211  in only 8 min with sufficient precision for isotopic measurements.
212                                   A Bayesian isotopic mixing model was used to determine the relative
213                                          The isotopic niche of consumers represents biologically rele
214 lization density (KUD) estimators to measure isotopic niche size and overlap.
215                                          The isotopic niche width (SEAs) of Carn Mor mice in each sea
216 rasian steppe over time, and an expansion of isotopic niche widths, indicate that historic Mongolian
217 strate the performance of the package kernel isotopic niches in r (rKIN) under various scenarios.
218 logenetic and biogeographic histories on the isotopic niches occupied by mammals in analogous tropica
219                  Based on the combination of isotopic observations derived from a re-sampling campaig
220 ogical classifications in bioapatite-protein isotopic offset expectations, must be reconsidered.
221 or using AA delta(13) C and delta(15) N, and isotopic offsets among AAs (e.g. Delta(15) N(Pro-Phe) ),
222                                              Isotopic oxygen tracer experiments support a Mars van Kr
223                                              Isotopic partition-function ratios (IPFRs) computed for
224                 Deconvolution of overlapping isotopic patterns indicated that in apples, only 5% of t
225 uble bonds (Deltam/z = 0.0025) and the first isotopic peak overlaps with ammoniated ions of a species
226                                 In addition, isotopic peaks from an enriched metabolite tend to have
227  responsible for substrate deprotonation and isotopic preferences in AMT pores and that decreased dep
228                                          The isotopic profile deconvoluted chromatogram algorithm was
229 Integration of metabolite concentrations and isotopic profiles reveals a reduced de novo biosynthesis
230  since it was simultaneously metabolomic and isotopic profiling.
231 g Hurricane Otto, rainfall exhibited a large isotopic range, comparable to the annual isotopic cycle.
232                                Here, we used isotopic rate measurements and metagenomic sequencing to
233 accompanied by a decrease in its (13)C/(12)C isotopic ratio (delta(13)C(CH4)) from -47.1 per mille to
234 d the investigation of the (108m)Ag/(110m)Ag isotopic ratio in the aftermath of a nuclear power plant
235                                        Using isotopic ratio mass spectrometry (IRMS) measurements, th
236 ter reflect the measured bulk values, as the isotopic ratio of 91% of collagen N can now be determine
237                                       The Hf isotopic ratios ((176)Hf/(177)Hf) of submarine lavas fro
238                                       The Pb isotopic ratios determined in both series of samples cle
239                          The (135)Cs/(137)Cs isotopic ratios in Danish soil (2.08-2.68) were signific
240 ney water alongside with carbon and hydrogen isotopic ratios of ethanol obtained from honey fermentat
241 in literature is the evaluation of different isotopic ratios of the elements, but other techniques co
242 n produce the apparent stepwise jumps in the isotopic record when coupled to long-term changes in bur
243 ) strength are documented, most commonly, in isotopic records from speleothems, but less is known abo
244                                     By using isotopic reference materials, each measured isotopic abu
245 ia atom probe mass spectrometry, on U(3)O(8) isotopic reference materials.
246                                              Isotopic relationships described here reveal the plastic
247  existence of species- and location-specific isotopic relationships with physical and environmental f
248 ctosidase (466 kDa), extending the limits of isotopic resolution for high mass and high m/z by >2.5-f
249 harge detection mass spectrometry, we report isotopic resolution for pyruvate kinase (232 kDa) and be
250 ltiple charge states and potentially without isotopic resolution.
251  provides direct experimental evidence of an isotopic scrambling mechanism.
252 e plutonium purification, concentration, and isotopic screening in a fieldable detection system will
253                             We find that the isotopic seasonal cycle in this region is driven by a sh
254 d groundwater were shown to have contrasting isotopic selectivities for common organic compounds.
255 itions with near-perfect chemo-, stereo- and isotopic selectivity.
256 bromoanilines exhibit qualitatively distinct isotopic shifts under identical conditions, some changin
257 be identified by comparing their theoretical isotopic signal with the observed peaks.
258                                          The isotopic signature along the microbial mat profile follo
259                                    The DUPAL isotopic signature at VFR demonstrates for the first tim
260 -(3)He/(4)He OIB exhibit anomalous (182)W-an isotopic signature inherited during the earliest history
261                                          The isotopic signature of DIC became significantly more enri
262                        Emerging markers like isotopic signature of honey water alongside with carbon
263  the Late Neolithic had already impacted the isotopic signature of rodents in the ecosystem.
264 d may be derived from another source with an isotopic signature similar to that of marine phytoplankt
265 ity, external carbonic anhydrase (CA(ext) ), isotopic signatures (delta(13) C) and growth among size-
266 quantitative experimental evidence of triple-isotopic signatures of water-metabolism in the human bod
267           We use the stable-and radio-carbon isotopic signatures of wetland sediment methane, ecosyst
268  that suspicious Bordeaux wines displayed Pb isotopic signatures statistically distinctive from those
269  the previous 50 years with a clear shift of isotopic signatures towards geogenic values correspondin
270 ring the interglacial period known as Marine Isotopic Stage 11 (MIS11), the global temperature was 1
271 (13)C-metabolic flux analysis, principles of isotopic steady state have been used to study heterotrop
272                                    Strontium isotopic stratigraphy using (87)Sr/(86)Sr ratios of all
273 ailable with its ability to resolve the fine isotopic structure of measured analytes.
274                                              Isotopic studies inferred the temperature of photosynthe
275                                              Isotopic studies with (13)C(6)-d-glucose and D(2)O unamb
276 g modes, were confirmed by (13) C and (15) N isotopic substitution and comparison with frequencies ca
277                                              Isotopic substitution has long been used to understand t
278 ts belonging to a single atom at the site of isotopic substitution, reveals a remarkable result for b
279 analysis and establish a novel comprehensive isotopic targeted mass spectrometry (CIT-MS) method for
280 ed across the reef with that predicted by an isotopic thermometer suggests complex interactions betwe
281 degradation of CH(3)Cl provides an effective isotopic tool to characterize and distinguish between ma
282 in conjunction with the use of an additional isotopic tool-sulfur isotope analysis (delta(34)S) of AE
283 ther (micro)organisms, analytical platforms, isotopic tracers, or classes of metabolites.
284 , and castor (Ricinus communis), followed by isotopic tracing of glycerol flux through the lipid meta
285 ation of primary cell culture studies, (13)C isotopic tracing, laser microdissection experiments, and
286                                 Steady state isotopic transient kinetic analysis (SSITKA) of ammonia
287 ase since 2008 (while noting that the global isotopic trend is the net of all dynamic source and sink
288          These high and distinctly different isotopic values are inconsistent with equilibrium fracti
289                       Variability in H. tuna isotopic values even among closely located individuals s
290  than 660 kilometres) have a narrow range of isotopic values that are typical of mantle that has expe
291 s, successfully determined that the range of isotopic values that characterized Greek samples was 52%
292 bon (delta(13) C) and nitrogen (delta(15) N) isotopic values to reflect consumption patterns and trop
293 e the microbial community and correlate with isotopic values.
294 ble isotope mixing models and tested how the isotopic variance of basal resources, primary consumers,
295 ly monitoring all singly substituted, stable isotopic variants of N(2)O.
296           There was no effect of land use on isotopic variation of basal resources, primary consumers
297 eoenvironmental studies such as tracing past isotopic variations in the global hydrological cycle.
298 anomalous (182)W and examine how Sr-Nd-Hf-Pb isotopic variations-useful for tracing subducted, recycl
299  precision of MC-ICP-MS analysis and smaller isotopic variations.
300  amines thus has been demonstrated by tuning isotopic water and methanol.

 
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