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2 etaproteomic strategy, using in vitro stable isotopically ((15)N) labeled microbiota as a spike-in re
3 nd modern shells of limpets and mussels were isotopically analysed to explore changes in the isotopic
5 16:1n-7/16:0) in VLDL-TG was associated with isotopically assessed DNL (r = 0.13, P = 0.1 and r = -0.
7 nalysis of ubiquitination is reported, named isotopically balanced quantification of ubiquitination (
8 , delta(13)C(hair), and delta(15)N(hair), we isotopically characterized aspects of feeding ecology in
9 ican kestrels (Falco sparverius) were fed an isotopically characterized diet and patterns in delta(15
10 th methods provided that a consistent set of isotopically characterized reference materials is used.
11 tio of 16:0 to 18:2n-6; P = 0.03), which was isotopically confirmed by DNL(Meas) (increased 2.5-fold;
12 he 2010s, South African SRWs foraged on prey isotopically consistent with the waters of the Subtropic
13 ve used the redshifts and line shapes of the isotopically decoupled IR oxygen-deuterium (O-D) stretch
15 mi-closed basin and the assumed influence of isotopically depleted freshwater yielded by fluvial syst
16 m ashes collected in these power plants were isotopically depleted in the heavy isotopes relative to
18 cally enriched, modern DOC cocycling with an isotopically depleted older fraction in the upper ocean.
20 zed, REE-rich fluids, derived from external, isotopically depleted sources, metasomatized the granite
22 The method treats explicitly the cleavage of isotopically different C-Cl bonds and thus considers, si
23 riments were analyzed and calibrated against isotopically different reference standards for both CCl4
25 Under increasing methanol concentrations, isotopically distinct 1,2-dimyristoyl-sn-glycero-3-phosp
28 fuel pellets that were made by blending two isotopically distinct feedstocks, we show that EUV TOF c
29 d used, drinking water delta(18)OPO4 appears isotopically distinct from a number of other phosphorus
30 es that the regional background Hg source is isotopically distinct in both Delta(199)Hg and delta(202
31 e show that the subducted flux of uranium is isotopically distinct, with high (238)U/(235)U ratios, a
34 e report here on the synthesis and use of an isotopically double-labeled Abeta1-15 glycopeptide, carr
36 oyed to construct (13)C horizontal line(18)O isotopically edited amides to permit direct observation
37 ed from multiple sets of site-specific (13)C isotopically edited infrared (IR) and circular dichroism
39 e-specific thermal unfolding probed by (13)C isotopically edited IR is likewise consistent with prima
42 We have illustrated a novel way of using isotopically enhanced two-dimensional NMR spectroscopy t
43 erentially labeled RT was reconstituted from isotopically enriched ((15)N-labeled) p51 and unlabeled
45 spin flips of residual (29)Si nuclei in the isotopically enriched (28)Si host material, which occur
46 ystalline lepidocrocite were reacted with an isotopically enriched (57)Fe(II) solution (0.1 or 1.0 mM
48 n studies using flow injection analysis with isotopically enriched (99)Ru as a carrier with ICP-MS de
50 GSSG measurement, the sample was spiked with isotopically enriched analogues of the analytes ((310)GS
53 ied out by the chlorination of biphenyl with isotopically enriched chlorine gas, generated by the dir
57 Furthermore, crossover experiments with an isotopically enriched exogenous copper source illustrate
60 oscopy, electrospray mass spectrometry using isotopically enriched hydrogen peroxide, and density fun
61 NMR and MS, including a (13)C-(13)C COSY of isotopically enriched material, degradation, derivatives
62 roviding cells, animals, or patients with an isotopically enriched metabolite (e.g., (13)C, (15)N, or
63 amine precursors for melanization to produce isotopically enriched pigment "ghosts" and applied 2D (1
64 NMs, namely ZnO, CuO, Ag, and TiO(2), using isotopically enriched precursors, namely (67)Zn or (68)Z
67 high-sensitivity (29)Si NMR spectroscopy of isotopically enriched solutions combined with theoretica
68 in) via the (63)Cu(p,n)(63)Zn reaction using isotopically enriched solutions of (63)Cu-copper nitrate
69 g experiments in biology usually make use of isotopically enriched substrates, with the two most comm
72 ino acid type, or a limited subset of types, isotopically enriched with (15)N or (13)C, is described.
78 embrane components, if CO2 was assumed to be isotopically equilibrated with cytosolic water, and the
80 veloped an integrated pipeline that combines isotopically fluorous tag labeling and fluorous solid-ph
81 is sufficiently volatile such that it may be isotopically fractionated during incomplete condensation
82 t, evolved plume rocks (tholeiitic) are more isotopically fractionated in Ti than differentiated isla
85 (South Africa), which reveals a smaller and isotopically heavier flux of dissolved iron to seawater
86 and show that all differentiated bodies have isotopically heavier magnesium compositions than chondri
87 atio determines whether coccolith calcite is isotopically heavier or lighter than abiogenic calcite,
88 The delta(82/76)Se of water-soluble Se is isotopically heavier than delta(82/76)Se of adsorbed Se,
89 otopes were markedly fractionated: straw was isotopically heavier than roots (Delta(114/110)Cdstraw-r
91 thermore, synglacial sedimentary nitrogen is isotopically heavier than the modern atmosphere, requiri
92 achates due to root-induced mobilization was isotopically heavier than the Zn released in the absence
93 more than 10,000 petagrams)-and, on average, isotopically heavier-carbon source than considered previ
94 d by less sea ice, a greater contribution of isotopically heavy Arctic-derived moisture, and wetter c
97 cal isotope fractionation cannot explain the isotopically heavy Tl in the Lengerich topsoils and the
98 a spatiotemporally variable transition from isotopically heavy to isotopically light compositions.
99 igands we found preferential partitioning of isotopically heavy zinc in the complexed form, and the e
100 iron within the surface mixed layer becomes isotopically heavy, reflecting the dominance of biologic
102 e magma reservoirs by repeated injections of isotopically heterogeneous magma batches and short pre-e
104 at larger spatial scales, than analyzing the isotopically highly heterogeneous tailing piles typicall
106 ted by the cyclotron and has the capacity to isotopically label peptides of choice for positron emiss
109 trix-matched calibration standards and using isotopically labeled (IL) analogues as internal standard
110 curring isotopologue transitions of a stable isotopically labeled (SIL) analyte for instant liquid ch
111 logue reaction monitoring (MIRM) of a stable isotopically labeled (SIL) analyte, dilution of study sa
116 silon-NH(2) group of the C-terminal Lys with isotopically labeled acetyl-alanine; (3) thiol Michael a
117 yl-alanine; (3) thiol Michael addition of an isotopically labeled acetyl-cysteine at the maleylated N
121 s sampling bag, where it is homogenized with isotopically labeled analogue internal standards and sam
123 ns expressed by a eukaryotic organism can be isotopically labeled and produced with a quality and qua
124 vestigation of a reaction mixture containing isotopically labeled and unlabeled reactants with differ
127 s by hydrolyzing peptidoglycan isolated from isotopically labeled bacterial biomass and used them as
128 ated from (13)COgen, the corresponding (13)C-isotopically labeled beta-ketonitriles were obtained, an
129 Correspondingly, we constructed a library of isotopically labeled bottlebrush molecules and measured
131 ll (hiPSC)-derived neuroprogenitors using an isotopically labeled cholesterol precursor and by monito
132 as greatly enabled by the synthesis of a new isotopically labeled cholesterol standard and correspond
136 ectrometry experiments using (17)O and (18)O isotopically labeled compounds prove that this compound
143 ct mass-to-charge ratios in combination with isotopically labeled experiments exploiting reflectron t
144 They consumed a maize meal fortified with isotopically labeled ferrous sulfate (FeSO4; study 1) or
146 The isolated phosphoproteins were eluted and isotopically labeled for relative and absolute quantitat
147 omic-SIP is a valuable method for recovering isotopically labeled genomes from complex communities.
148 mic-SIP improves the assembly and binning of isotopically labeled genomes relative to a conventional
150 al by direct and quantitative measurement of isotopically labeled glutathione introduced exogenously
152 xtraction cartridges followed by addition of isotopically labeled glyphosate to the final test sample
153 nMS for the identification of differentially isotopically labeled heteroconjugates against a complex
154 have tested different methods of applying an isotopically labeled internal standard for MALDI IMS ana
157 2'-deoxyribose-cysteine adduct, addition of isotopically labeled internal standard, and quantitation
160 Chlorinated and brominated standards and isotopically labeled internal standards were synthesized
161 chromatography, a diastereomeric mixture of isotopically labeled internal standards, and multiple re
164 tes using authentic metabolite standards and isotopically labeled internal standards, whereas the cor
166 central nervous system proteins with stable isotopically labeled leucine was performed, and kinetics
167 n, on 2 consecutive days, we fed all infants isotopically labeled maize porridge and MNP test meals c
169 tly, LC/MS-based untargeted metabolomics and isotopically labeled metabolites have been used to facil
170 tabolomic technologies to track the fates of isotopically labeled metabolites in a global, unbiased m
174 ecific, spatially resolved identification of isotopically labeled molecules with the electron microsc
176 Mass spectrometry of the reaction between isotopically labeled mu-(16)O(bridging-oxo) 1A(+) and (1
177 provides for a unified synthetic approach to isotopically labeled N-methylanilines from various stabl
178 ammonium-free media, and fail to incorporate isotopically labeled N2 gas into biomass in multiple ind
180 tual replacement of radiotracers with stable isotopically labeled ones, even for adult clinical inves
182 in situ infrared (IR) spectroscopy and with isotopically labeled oxygen ((18)O), appears to be criti
188 onjunction with solution NMR spectroscopy of isotopically labeled Pgamma identified the central polyc
191 etabolism and can be achieved by tracking an isotopically labeled precursor to an unexpected product.
194 requires little protein, avoids the need for isotopically labeled protein, and has no protein molecul
196 tended for the analysis of experiments using isotopically labeled reference peptides for absolute qua
198 ains is achieved using a stalling motif, and isotopically labeled RNCs are produced at high yield usi
199 Here, we present a strategy to generate isotopically labeled RNCs in Escherichia coli that are s
202 nce (ENDOR) measurements with (13)C and (2)H isotopically labeled SAMCA support a pi-complex between
203 n, including secondary structure at specific isotopically labeled sites, intramolecular and intermole
204 ptides that were obtained from unlabeled and isotopically labeled soybean embryos and Escherichia col
205 The utility of a homogeneously coated stable-isotopically labeled standard (SIL) for normalization wa
206 followed by a homogeneously applied, stable, isotopically labeled standard for normalization and a ma
210 ies on commercial cross-linkers that bear an isotopically labeled tag and N-hydroxysuccinimid-ester (
212 aspects: (i) a general method for producing isotopically labeled TM or membrane-proximal (MP) protei
213 ifies Tn by glycosyltransferase C1GalT1 with isotopically labeled UDP-Gal((13)C(6)), to tag and conve
214 ified by 9.5 and 140 GHz EPR spectroscopy on isotopically labeled varieties of the protein to be a th
215 ropose a novel approach that applies several isotopically labeled versions, each at a different conce
217 beled tyrosine substrates, the cyanides were isotopically labeled via a recently developed in vitro m
218 arbon-hydrogen bonds in a single step, using isotopically labeled water (D2O or T2O) as the source of
219 temperature-programmed desorption (TPD) with isotopically labeled water and oxygen species, reactive
222 surements, maltose binding protein (MBP) was isotopically labeled with (13)C and (15)N, permitting dy
224 tion of aqueous solutions of ferrous sulfate isotopically labeled with (5)(4)Fe, (5)(7)Fe, or (5)(8)F
226 ed, hydroxylated), and labeled (fluorinated, isotopically labeled) side chains to be added to a commo
227 , when a high proportion of the community is isotopically labeled, the benefits of metagenomic-SIP de
231 posome analytical platform (CIL-EXPOSOME) by isotopically labeling urinary biomarkers with common fun
232 eomic analyses of the sheath-water bacteria, isotopically labelled in situ, indicate their slow growt
234 in their natural environment, but sorting of isotopically labelled microbial cells from complex sampl
235 o address this, we report the application of isotopically labelled peptide sequence MSTKDFNLDLVSVSKKD
236 t is helpful to study the flow of label from isotopically labelled precursors into other metabolites
239 resent the first report using broad-spectrum isotopically labelled standards for quantitative charact
241 ImCal relies on the use of five different isotopically-labelled peptides of different nominal mass
243 ess effect, that is, fossil fuel-derived and isotopically light carbon being incorporated into marine
245 h system, where rapid and massive release of isotopically light carbon led to a major perturbation in
246 terrestrial sediments attest to the input of isotopically light carbon, although the carbon sources r
249 vents in the North Atlantic are a source of isotopically light iron, which travels thousands of kilo
252 s are the geogenic background, as defined by isotopically light soils at depth (epsilon(205)Tl approx
255 iments on mare basalt 14053 demonstrate that isotopically light Zn condensates also occur on some mar
256 first period of life, Hg in the liver became isotopically lighter (delta(202)Hg decreased) with a str
257 her hydrologic activity a higher wash out of isotopically lighter nitrate formed by bacterial nitrifi
258 pth indicating the preferential migration of isotopically lighter Se downward through the soil profil
259 f -0.15 per thousand with the adsorbed U(VI) isotopically lighter than coexisting aqueous U(VI).
260 ntial dissolved flux to the oceans, which is isotopically lighter than the crust, and so may be disti
262 ns, the Cu flowing out of the wetland became isotopically lighter, indicating the mobilization of red
263 y suggests that changing emissions of other (isotopically-lighter) CH(4) source terms is dominating t
264 ircular) and the probability of detecting an isotopically marked adult at different distances from th
265 se has not been validated by comparison with isotopically measured de novo lipogenesis (DNL(Meas)).
270 13)C record, and consequent contributions of isotopically negative terrestrial organic matter to the
271 oth steady-state metabolic flux analysis and isotopically non-stationary metabolic flux analysis.
273 ly orientated needle-like crystals in SA and isotopically ordered braid-like crystals in GMS oleogels
275 properties of low-loss phonon polaritons in isotopically pure hexagonal boron nitride interacting wi
276 lectronic states were measured for different isotopically pure RaF molecules using collinear resonanc
277 tron and nuclear spins of donor ensembles in isotopically pure silicon experience a vacuum-like envir
280 the ultrahigh resolving power of FT-ICR, we isotopically resolved 31 distinct proteoforms (30-50 kDa
281 onized ICR cell, i.e., ParaCell, for mapping isotopically resolved intact proteins up to about 17 kDa
282 transfer to the LTQ Orbitrap XL instrument, isotopically resolved mass spectra could be acquired.
284 ion of metal cations and ligands can also be isotopically resolved with the ultrahigh mass resolution
286 ity to perform not only elementally but also isotopically sensitive detection and analysis at standof
288 +/- 5.7 J mol(-1) K(-1)) to a species 3 with isotopically sensitive stretches at nuO-O(Delta(18)O) =
289 he 1990s, South African SRWs foraged on prey isotopically similar to South Georgia/Islas Georgias del
290 udies has gradually expanded to include both isotopically steady-state and transient labeling experim
291 stitutions, we studied a mixture of specific isotopically substituted ((15)N, (13)C, and (2)H) proton
293 , isotope effects derive from differences of isotopically substituted molecules in isotope vibrationa
296 how how multidimensional NMR spectroscopy of isotopically tagged molecules enables structure characte
298 titative chemoproteomic platform, which uses isotopically tagged, photocleavable azido-biotin reagent
300 e to determine candidate identifications for isotopically unresolved proteoforms larger than 50 kDa,