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1 get in each individual (i.e. the critical AT isthmus).
2 specificity for identifying the clinical VT isthmus.
3 med at the pulmonary vein and cavo-tricuspid isthmus.
4 ned vertebral phenotype featured by lamellar isthmus.
5 al of most midbrain/hindbrain cells near the isthmus.
6 71%) had an identifiable endocardial circuit isthmus.
7 tified to attempt to trace the course of the isthmus.
8 ding projections beyond the diencephalon and isthmus.
9 the incidence and microscopic anatomy of the isthmus.
10 t mapping overestimates the true size of the isthmus.
11 was consistent with entrainment criteria for isthmus.
12 s quiescent stem cells in the gastric corpus isthmus.
13 arrowest accessible slow-conducting critical isthmuses.
14 mic isthmuses containing VT re-entry circuit isthmuses.
19 ength, 3.9+/-1.08; thickness, 1.5+/-0.3 cm), isthmus 1B intermediate dimensions (mean length, 2.4+/-0
21 th, isthmuses 1A and 1B were present in 88%, isthmus 2 in 25%, isthmus 3 in 94%, and isthmus 4 in 13%
22 th, 2.4+/-0.8; thickness, 1.1+/-0.4 cm), and isthmuses 2, 3, and 4 the smallest dimensions (mean leng
23 ) was significantly shorter than the central isthmus (24 mm +/- 4.3; range, 12-43 mm) and the central
24 l isthmus was shorter than the inferolateral isthmus (27 mm +/- 4.8; range, 13-45 mm) (P < .001).
28 es (N=30) were less commonly observed within isthmuses (3.3%, P<0.001) or within 5 mm of the leading
29 ium roof (12 RF/22 PF), and 44 cavotricuspid isthmus (36 RF/8 PF) lines, with therapy duration times
32 cava isolation in 6 patients, cavotricuspid isthmus ablation in 5 patients, and ablation of sites of
34 block were thoroughly reviewed in 271 mitral isthmus ablation procedures undertaken among 236 patient
36 Among the 105 patients who did not undergo isthmus ablation, 25 patients (24%) were documented to h
37 on was performed followed by roof and mitral isthmus ablation, before CFAE ablation in the CFAE arm.
47 ed the intra-mural segment, 14 presented the isthmus and 15 presented the ampulla and fimbria segment
50 e show that Gli3 regulates patterning of the isthmus and cerebellar anlage by confining Fgf8 expressi
51 and E11.0, Gli3 continues to be required for isthmus and cerebellum development, but primarily for de
53 or establishing a distinct posterior tectum, isthmus and cerebellum, but does not play a role in the
54 deling studies recapitulated DEEPs at the VT isthmus and demonstrated their role in VT initiation wit
55 on (CI) was performed incorporating putative isthmus and early exit site(s) based on standard criteri
56 ontractions of the muscles in the pharyngeal isthmus and function systemically to regulate an enhance
59 procedural success (transection of anatomic isthmus and noninducibility) and freedom of VT recurrenc
60 differences in the median dimensions of the isthmus and path length between fast and slow VTs and be
64 Adult D673V homozygotes exhibit dysplastic isthmus and reduced bone volume of the dorsal vertebra r
66 d to be restricted to the Western end of the Isthmus and the "militaris" phenotypes restricted to sit
68 s this, we conditionally ablated Fgf8 in the isthmus and uncovered that prolonged expression of Fgf8
71 r anlage by confining Fgf8 expression to the isthmus, and attenuates growth of dorsal r1 (before E11.
73 secondary gustatory/visceral nucleus in the isthmus, and for distinguishing territories in the prima
74 ng for the loss of brain structures near the isthmus, and instead demonstrate that tissue transformat
75 regions such as the midbrain tectum, dorsal isthmus, and motor nuclei, ASP and GABA immunoreactivity
76 m body, anterior midbody, posterior midbody, isthmus, and splenium) and for overall CC size, with lef
77 pital fasciculus, internal capsule, callosal isthmus, and the corona radiata (p=0.04 for FIQ and p=0.
79 es that target both scar-related and classic isthmuses appear necessary to prevent long-term recurren
80 targeted deletion of PPARgamma in the bulge/isthmus area of the hair follicle epithelium generates a
81 iculum of the isthmus (PaSi), area 29 of the isthmus (area 29i) and area prostriata (Pro), which has
82 ial slowing during SR corresponded to the VT isthmus (area under curve=0.84 95% CI, 0.78-0.90) while
83 6 of the 19 patients, a total of 41 distinct isthmus areas of 41 distinct VTs were identified and suc
84 in comparison with controls, although aortic isthmus/arterial duct diameter ratio was lower in fetuse
85 8 signaling from the mid/hindbrain boundary (isthmus) as being responsible for induction of different
86 part of the cingulum and the cingulate gyrus isthmus, as well as the precuneal GM, may be distinctive
87 ngeal muscles and marginal cells forming the isthmus between the anterior and posterior pharyngeal bu
88 accharomyces cerevisiae they localize at the isthmus between the mother and the daughter cells, where
90 sal r1 (before E11.0) and the dorsal mes and isthmus (beyond E11.0) through regulation of cell prolif
93 is study evaluates the long-term efficacy of isthmus block for treatment of re-entry VT in adults wit
95 the focal PFA catheter, acute cavotricuspid isthmus block was achieved in 13 of 13 patients (median:
97 uch-up lesions was necessary to complete the isthmus block with conventional fluoroscopy (median, thr
98 ictors for unsuccessful bidirectional mitral isthmus blockade were the need for epicardial ablation f
100 cardiomyopathy, obliteration of a conductive isthmus both anatomically and functionally and abolition
101 r versus parallel to the line of block along isthmus boundaries (19.3+/-7.1 versus 13.6+/-7.4 cm(2),
103 l in which Wnt regulates FGF activity at the isthmus by driving both FGF and Sprouty gene expression.
108 Atrophy in mesial and lateral temporal, isthmus cingulate, and orbitofrontal areas aided discrim
110 , across Beringea, and across the Panamanian isthmus coincide in timing and location with multiple we
115 ow-up, WM volume in the left cingulate gyrus isthmus correlated with clinical scores of anxiety (Spea
116 m of the study was to determine whether a VT isthmus could be identified and followed by pace mapping
118 ined endocardial and epicardial mapping, the isthmus could be identified in 56 (63%) ICM VTs and 12 (
120 or scar-dependent (n = 15) and cavotricuspid isthmus (CTI)-dependent (n = 14) flutter were studied.
121 al fibrillation may experience cavotricuspid isthmus (CTI)-dependent atrial flutter during follow-up.
124 cy lesions created a substrate for sustained isthmus-dependent AFL, confirmed by endocavity mapping.
126 t atrial tachycardias included cavotricuspid isthmus-dependent atrial flutter (n=7), non-isthmus-depe
127 us-dependent atrial flutter (IDAFL) from non-isthmus-dependent atrial flutter (NIDAFL) from the elect
128 rial tachycardia was seen in 7 patients, and isthmus-dependent atrial flutter occurred in 14 patients
129 ring 66 ATs in 62 patients: 20 cavotricuspid isthmus-dependent ATs, 20 perimitral ATs, 13 focal ATs w
134 ease with preserved ventricular function and isthmus-dependent re-entry, VT isthmus ablation can be c
135 isthmus-dependent atrial flutter (n=7), non-isthmus-dependent right atrial reentry (n=7), and 1 foca
136 -macro-re-entrant (perimitral, cavotricuspid isthmus-dependent, and roof-dependent circuits) versus c
139 ate for the initial block at the mouth of an isthmus/diastolic channel leading to ventricular tachyca
141 ograms were indicative of spatially confined isthmus dimensions, confirmed by rapid termination of VT
142 est: the optic tectum, torus semicircularis, isthmus, dorsal and medial nuclei of the octavolateral a
143 size that HSPGs are necessary for pharyngeal isthmus elongation, and pyr-1 functions upstream of prot
144 t pyr-1(cu8) exhibiting defective pharyngeal isthmus elongation, cytoskeletal organization defects, a
146 ansion and the repolarizing cells within the isthmus enabled retrograde flow of depolarizing electrot
147 ere slowest at the inward curvature into the isthmus entrance (0.28+/-0.2 m/s), slightly faster at th
148 h gastric mucus neck cells located below the isthmus express trefoil factor family 2 (TFF2) protein,
150 blation has been used to target the critical isthmuses for re-entrant monomorphic ventricular tachyca
152 ing and the relationship to the protected VT isthmus identified by entrainment mapping is unknown.
153 sful ablation sites were localized within an isthmus identified by pace mapping in all of these 10 pa
155 ed RFCA for VTs dependent on septal anatomic isthmuses improves ablation outcome in repaired Tetralog
157 lopment and becomes restricted mainly to the isthmus in adult glands, akin to its known localization
159 ) in repaired Tetralogy of Fallot focuses on isthmuses in the right ventricle but may be hampered by
166 with the addition of epicardial mapping, the isthmus is less commonly identified, possibly due to mid
167 timing of dispersal or vicariance across the Isthmus is not explained by the ecological factors teste
168 whereas the absence of Gly-ir neurons in the isthmus is shared by all these species, except for lampr
171 e that the CV of the outer loop, rather than isthmus, is the principal determinant of the rate of VT.
172 ovides an evaluation of the ET cartilage and isthmus level, which are small but important anatomical
176 ary vein isolation in 50 (100%), left atrial isthmus line in 47 (94%), anterior line in 45 (90%), com
178 essment of bidirectional block across mitral isthmus linear lesion using differential coronary sinus
179 round the left septum primum with a critical isthmus located between the pulmonary veins posteriorly
180 tes (N=27) were more commonly located within isthmuses <15 mm wide (67% versus 6.7%, P<0.00001; odds
181 on wavefront running perpendicular to the VT isthmus may increase sensitivity to detect arrhythmogeni
183 ed by entrainment exceeded dimensions of the isthmus measured by activation mapping by 32+/-18%.
187 n strategies, ablations of the cavotricuspid isthmus (n=4), fossa ovalis (n=4), and pulmonary veins (
188 ively cycling stem cells maintaining the pit-isthmus-neck region through a process of "punctuated" ne
192 d BZ channels identified 74% of the critical isthmus of clinical VTs and 50% of all the conducting ch
193 gene Axin2, is limited to the base and lower isthmus of gastric glands, where the stem cells reside.
198 des occurred at 4.90 Ma, indicating that the Isthmus of Panama allowed genetic exchange until the Pli
199 the oldest lineage entered the basin via the isthmus of Panama and sequentially established aggregati
200 spatially-segregated populations within the Isthmus of Panama could reveal how genetic differences a
201 he linking of North and South America by the Isthmus of Panama had major impacts on global climate, o
207 reater connectivity in the posterior midbody/isthmus of the corpus callosum and that fractional aniso
208 ed that diffusion anisotropy in the body and isthmus of the corpus callosum was negatively correlated
209 on, and diffusion anisotropy in the body and isthmus of the corpus callosum was shown to mediate this
210 responsive Axin2(+)Lgr5(-) stem cells in the isthmus of the gastric gland and finally gastric gland h
214 any critical component (defined as entrance, isthmus or exit) could be identified in 76 (85%) ICM VTs
215 a before the first humans crossed the Bering Isthmus or the onset of climate changes during the termi
216 cy results in reduced Fgf8 expression in the isthmus organiser (IsO), an embryonic signalling centre
219 of the isthmus (PrSi), parasubiculum of the isthmus (PaSi), area 29 of the isthmus (area 29i) and ar
222 ing have no defects in pharyngeal pumping or isthmus peristalsis rates, but their growth defect depen
223 t of the two motions were distinct, but each isthmus peristalsis was coupled to the preceding pump.
228 s analyzed in 546 adult COA patients, aortic isthmus ratio had the strongest correlation with e' (bet
229 indices stipulated in the guidelines, aortic isthmus ratio had the strongest correlation with LV dias
230 pper-to-lower-extremity SBP gradient, aortic isthmus ratio, presence of collaterals, and exercise-ind
236 nce of lmx1b.1 and lmx1b.2 expression at the isthmus requires the function of no isthmus/pax2.1, as w
238 cond ablation was performed either along the isthmus (scar-dependent group) or from the scar to anoth
239 nus rhythm, pace mapping near the exit of an isthmus should produce a QRS similar to that of VT.
240 encephalon, diencephalon, mesencephalon, and isthmus showed some deviation from the main scheme.
241 pping data were analyzed from the identified isthmus site and from sites at progressively increasing
245 Radiofrequency ablation was performed at isthmus sites as defined by pace-mapping (perfect pace-m
246 was to identify ventricular tachycardia (VT) isthmus sites by pace-mapping within scar tissue and to
255 ting of two wide regions connected by a thin isthmus.Structural heterogeneities provided a substrate
256 at inferior levels and the midbrain-pontine isthmus suggests a vulnerable region of passage for comp
257 on standard characterization of suspected VT isthmus surrogates thus limiting ablation target size.
258 preoptic area, ventral hypothalamus, nucleus isthmus, tectum mesencephali, inferior colliculus, and h
259 on in the isthmus between the TA and IVC (TI isthmus) terminated the tachycardia in all patients.
262 halamus, the habenula, the optic tectum, the isthmus, the cranial motor nuclei, and the spinal motor
265 tionship of the ventricular tachycardia (VT) isthmus to channels of preserved voltage on an electroan
267 the incidence and microscopic anatomy of the isthmus to provide more precise anatomical information a
269 ft side, and (3) left-sided RFCA resulted in isthmus transection and prevention of VT induction.
271 riate analysis, PDAC primary tumor location (isthmus vs head: hazard ratio [HR], 2.06; 95% CI, 1.09-3
273 cepted date of 3 million years ago (Ma), the Isthmus was effectively complete by the middle Miocene,
275 hermore, 22 of the 81 VTs (27%) for which no isthmus was identified became noninducible after ablatio
278 mm +/- 4.3; range, 12-43 mm) and the central isthmus was shorter than the inferolateral isthmus (27 m
280 e posterior left atrium and along the mitral isthmus, was performed under the guidance of an electroa
283 Conduction velocities within the shared isthmus were dependent on the activation vector, consist
290 t mating or insemination reaches the oviduct isthmus, where sperm are retained and thereby form a res
291 in positioning the mid/hindbrain organizer (isthmus), which regulates midbrain and cerebellar develo
292 nd (2) targeted illumination of the critical isthmus, which was identified via analysis of simulated
293 hibchan speakers on both sides of the Panama isthmus, who have ancestry from both North and South Ame
294 age channels with ILPs harbored the clinical isthmus with a sensitivity and specificity of 78% and 85
295 PPI <0 are markers of limited width critical isthmuses with slower conduction velocity, whereas sites
298 ally complex structures, particularly at the isthmus, with substrate for multiple VT morphologies aft
299 2 minutes) were formed at the cavo-tricuspid isthmus, with the end point of bidirectional block.
300 WM bilaterally and the left cingulate gyrus isthmus WM, as well as the right precuneal GM, showed si