ライフサイエンスコーパス: itchy

1 Itchy, a mouse homologue of human AIP4, is a Nedd4 famil

2 r activities to avoid the annoyingly intense itchy allergic reactions, leading to significant worseni

3 We compared the ability of ITCHY and DNA shuffling to create interspecies fusion li

4 The lesions tend to be less itchy and poorly responsive to standard therapy, includi

5 aracterized by recurring episodes of raised, itchy and sometimes painful wheals lasting longer than 6

6 was defined by parental report of a typical itchy and/or flexural rash.

7 uncation for the creation of hybrid enzymes (ITCHY) and SCRATCHY] and low-homology techniques (recomb

8 argasid tick which importance relies on its itchy bite and potential as disease vector.

9 Histamine is involved in a minority of itchy conditions, and many other mediators play a role:

10 defined as chronic or chronically relapsing itchy dermatitis lasting >6 weeks with characteristic mo

11 ndicate that Nedd4 family E3s, in particular Itchy, downmodulate LMP2A activity in B-cell signaling.

12 crophage polarization, which is regulated by itchy E3 ubiquitin ligase (ITCH), a negative regulator o

13 Itch or itchy E3 ubiquitin ligase was initially discovered by ge

14 In innate immunity, the itchy E3 ubiquitin protein ligase (ITCH)-A20 ubiquitin-e

15 orly controlled skin disease resulting in an itchy eruption that can be persistent.

16 Nine of them had infiltrated itchy erythematous and vesiculous plaques at the injecti

17 Five days after antibiotics were given, itchy exanthema occurred, followed by gland glass opacit

18 1.81; 95% CI: 1.41, 2.58); watery, burning, itchy eyes (OR = 1.61; 95% CI: 1.20, 2.16); and stuffy,

19 Moreover, itchy eyes had the higher symptom prevalence than watery

20 e 2nd year, and the 2nd year was better with itchy eyes than the 1st year (p<0.05).

21 visited our hospital because of nasal drop, itchy eyes, and dyspnea after lunch every two months for

22 allergic reaction occurs but can include red itchy eyes, sneezing, nasal congestion, rhinorrhea, coug

23 parental atopy, FLG status, or report of an itchy flexural rash at 2 months.

24 we identify the E3 ubiquitin-protein ligase Itchy homolog (ITCH) as a key regulator of proteotoxicit

25 on K1413 by the E3 ubiquitin-protein ligase Itchy homolog (Itch), a Nedd4 family member.

26 positives from each library illustrated that ITCHY identified a more diverse set of active fusion poi

27 As a model system, single-crossover ITCHY (incremental truncation for the creation of hybrid

28 Atopic eczema is an itchy inflammatory skin disease.

29 topic dermatitis (AD) is a highly prevalent, itchy inflammatory skin disorder that is thought to aris

30 uncation for the creation of hybrid enzymes (ITCHY) is a novel tool for the generation of combinatori

31 Homozygous itchy mice develop a fatal, late-onset autoimmune-like d

32 Itchy mice lack the E3 ligase, Itch, and show dysregulat

33 tions of immunoglobulin G1 (IgG1) and IgE in itchy mice were also increased.

34 e aberrant activation of immune responses in itchy mice.

35 ase that is disrupted in nonagouti-lethal or itchy mice.

36 at is disrupted in non-agouti lethal mice or Itchy mice.

37 This phenotype resembled that of Itchy mutant mice, suggesting that Ndfip1 might affect t

38 t least two symptoms: 'repeated sneezing and itchy nose', 'blocked nose for more than one whole hour'

39 1 rhinitis symptom (repeated sneezing and/or itchy nose, blocked nose for >1 h, or runny nose without

40 ocked nose, 48% rhinorrhea, and 46% sneezing/itchy nose.

41 braries generated by incremental truncation (ITCHY) of two distinct parental sequences are created, a

42 Pollen-AR was defined as sneezing, runny, itchy or blocked nose; and itchy or watery eyes when exp

43 sneezing, runny, itchy or blocked nose; and itchy or watery eyes when exposed to birch and/or grass

44 olor changes, and its deletion results in an itchy phenotype with constant skin scratching and multi-

45 Although itchy rash is a nonspecific manifestation, it may be con

46 ECTIVES To assess the prevalence of reported itchy rash lasting longer than 3 days among the general

47 Atopic dermatitis, defined as an itchy rash on typical locations from birth to 6 years.

48 ifetime age-standardized prevalence rates of itchy rash that lasted longer than 3 days.

49 The overall prevalences of itchy rash were 19.3% (95% CI, 18.6%-20.0%) during the m

50 s (allergy, hay fever, eczema, rhinitis, and itchy rash) and serum-specific immunoglobulin E (IgE) le

51 respiratory tract) and allergies (wheezing, itchy rash, asthma medication, food allergy) from age 2

52 (OR = 1.61; 95% CI: 1.20, 2.16); and stuffy, itchy, runny nose (OR = 1.56; 95% CI: 1.16, 2.08).

53 of drowsiness, hair loss, nausea, and dry or itchy scalp were reported while patients were receiving

54 eurons and is dependent on scratching of the itchy site.

55 A high amount of IL-6 was detected in itchy skin and blood of patients with CKD.

56 utoimmune disease phenotype characterized by itchy skin and multiorgan inflammation.

57 A hallmark of AD is dry itchy skin due, at least in part, to defects in skin gen

58 However, the rapidly progressive painful, itchy skin tightening that characterizes dcSSc is the sy

59 cond decade of life with self-described red, itchy skin within a large plaque of FDH on her left post

60 isease prognosis (by promoting scratching of itchy skin).

61 orted symptoms (rash, mouth or throat sores, itchy skin, and numbness or tingling in hands or feet) w

62 m, sparse and slow-growing hair, and dry and itchy skin.

63 The detection of pruritic (itchy) stimuli is mediated by a variety of receptors and

64 agia, altered gastrointestinal motility, and itchy swollen skin.

65 Furthermore, some of the hybrids found by ITCHY that were fused at nonhomologous locations had act

66 uncation for the creation of hybrid enzymes (ITCHY), that creates combinatorial fusion libraries betw

67 nother, as yet unidentified locus designated itchy (the provisional gene symbol is Itch), that is res

68 pper respiratory symptoms, including dry and itchy throat (64.16%), sore throat (59.95%), hoarseness

69 toms (paresthesia of the tongue, sore and an itchy throat).

70 with the most recent sexual partner; and (c) itchy vaginal discharge in the previous 30 d, possibly i

71 Self-reported itchy vaginal discharge was associated with all categori

72 ced odds of condom use and increased odds of itchy vaginal discharge, which is potentially indicative

73 high-school student experienced generalized itchy wheal and dyspnea during physical exercise after l

74 contact urticaria (CCU) is characterized by itchy wheal and flare responses due to the release of hi

75 ast cell-driven skin disease presenting with itchy wheals, angio-oedema, or both.

76 flammatory skin disorder that manifests with itchy wheals, angioedema, or both for more than 6 weeks.

77 ting skin disease characterized by intensely itchy wheals, angioedema, or both.