ライフサイエンスコーパス: juncture

1 sting patients and families at this critical juncture.

2 Human genetics is now at a critical juncture.

3 ns of the neuroaxis at the meso-diencephalic juncture.

4 ies or trials that have led to this exciting juncture.

5 r therapeutic interventions at this critical juncture.

6 in the United States has reached a critical juncture.

7 icted peptidomimetic linkers at the point of juncture.

8 and AA may interact at a number of critical junctures.

9 om different types of access barriers at key junctures.

10 e likely to occur at critical moral distress junctures.

11 An unusual A/B ring juncture, a feature associated with bile acids and no ot

12 This is significant because at this juncture aberrant MYC expression stubbornly resists any

13 oduct 1b was demonstrated to be the 6,6-ring juncture adduct on the basis of NMR experiments and X-ra

14 differing greatly from the "closed" 5,6-ring juncture adducts reported previously.

15 ch sensory information processed at critical junctures allows for flexible adjustments in component a

16 d we review research about stratification at junctures along student pathways into and through postba

17 task-centric analysis; we identify critical junctures and differences among types of tasks within th

18 , HORMA domain proteins occupy key signaling junctures and function through the controlled assembly a

19 are established at high Fsp(3) attached-ring junctures and the carboxylate directing group can be rem

20 protein (HSP) 40 at the spokehead-spokestalk juncture appear normal in length and composition but twi

21 t fully solved, we are poised at an exciting juncture, as insights from murine disease models are con

22 late transitional B-cell stage as a crucial juncture at which developing B cells gain access to sple

23 Residency selection is a crucial juncture at which diversity and representation in specia

24 The perimenopausal period may be a critical juncture at which targeted and tailored interventions ma

25 ngle-cell approaches to resolve the critical junctures at which perturbations initially amenable to c

26 activation of COP1 and a possible cross-talk juncture between auxin regulation and phytochrome signal

27 m its x-ray crystal structure, predicted the juncture between Domains II and III of delta.

28 ly of complex I, before the formation of the juncture between peripheral and membrane arms.

29 sults establish that TET proteins act at the juncture between somatic and germline fates: without TET

30 ggest possible meridional contraction at the juncture between the apical dome and the cell body.

31 genitor population in the sclerotome, at the juncture between the future lineages of muscle and carti

32 west folding, 10(2)-10(3) s-1, occurs at the juncture between the helix and sheet.

33 que protein desmoplakin (DP), located at the juncture between the intermediate filament (IF) network

34 or Xa, a serine protease, is at the critical juncture between the intrinsic and extrinsic pathways of

35 that a conserved Gly residue (located at the juncture between the linker and C-terminal domains) is a

36 matched via the movement of nodes, which are junctures between phase-mismatched cell regions.

37 Even this more limited goal is, at this juncture, beyond our reach, but the journey to this goal

38 The 6:6 ring juncture bonds of C(60) are centered over the porphyrins

39 The electron-rich 6:6 ring-juncture bonds of C60 show unusually close approach to t

40 ogression is controlled at several different junctures by the targeted destruction of cell cycle regu

41 onmental insults at particular developmental junctures can lead to complex brain malformations.

42 IL-6), chemokines related to host-commensal junctures (CCL19, CCL23, CCL3), and markers of monocyte

43 fungal and oomycete pathogens, are prominent junctures dictating infection outcomes.

44 Thus, junctured-DNA tweezers allow a straightforward and robus

45 Here, we introduce junctured-DNA tweezers as a generic platform that enable

46 ee of rigidity and D00 likely functions as a juncture domain at the outer membrane-extracellular medi

47 ss-linking by HMCES intercedes at a critical juncture during processing of vulnerable gapped DNA inte

48 GF-beta2 and TGF-beta3 commences at critical junctures during progression of nevi to primary melanoma

49 uorum sensing and swarming motility at a key juncture early in biofilm development.

50 ptional networks at two critical cardiogenic junctures: embryonic cardiogenesis, where it was particu

51 ive stage to a migratory stage is a critical juncture; errors in this process may result in tumor for

52 enriched for SARS-CoV-2 specificities, as a juncture for ASC and MBC differentiation, with CD86+ phe

53 At this important juncture for the field, the authors make predictions for

54 at the +15/+16 juncture, unlike the +11/+12 juncture for the wild type N25.

55 lizing alkyl linkers that connect the branch junctures from ethyl to n-pentyl moiety (C(2)G3-C(5)G3).

56 nic mercury emissions has reached a critical juncture, highlighting the urgent need to target reducti

57 chnical tools and knowledge, success at this juncture hinges more on a massive mobilization of effort

58 ofilm defence mechanism acting at a critical juncture in biofilm development, the time bacteria stop

59 rates, positioning the mollusk at a critical juncture in evolution of this gene family.

60 The U.S. health care system is at a critical juncture in health care workforce planning.

61 lake sediments at Olduvai Gorge during a key juncture in human evolution about 2.0 Ma--the emergence

62 of the prostate gland at puberty, a crucial juncture in prostate development that is androgen depend

63 R) type 1 and JNK3, placing it at a critical juncture in regulating signaling of neurodegeneration.

64 nd intracerebral hemorrhage (ICH), a pivotal juncture in stroke diagnosis and treatment algorithm, es

65 visual and saccade-related signals at a key juncture in the 'where' pathway.

66 8-FOXC2 signaling axis represents a critical juncture in the acquisition of metastatic competence, th

67 At this critical juncture in the development of NeuroAI, we outline chall

68 's correspondence in 1965-1966, an important juncture in the genesis of modern clinical research ethi

69 sition from mitosis to meiosis is a defining juncture in the life cycle of sexually reproducing organ

70 A defining juncture in the life of a T cell is its encounter with i

71 A critical juncture in the process is the identification of a prope

72 is consistent with reaction at the 6,6-ring juncture in the pyracylene unit of the D(5h) Sc(3)N@C(80

73 pe II (COPII) vesicles represents a critical juncture in the quality control of protein biogenesis wi

74 This intermediate marks a critical juncture in the reaction cascade, presenting multiple av

75 into the origins of introns is at a critical juncture in the resolution of theories on the evolution

76 ntrolled by Rab6 occur at or near a critical juncture in the trans-Golgi network where beta APP is so

77 nd the 12-nt synthesis represents a critical juncture in the transcriptional initiation pathway when

78 ing mental health conditions at this crucial juncture in their educational pathway.

79 gested that although they may have reached a juncture in their lives, at which they felt ready to hav

80 oop such as Asp1161 may function at multiple junctures in cellular regulation of receptor tyrosine ki

81 urational and experiential influences at key junctures in development and presenting paradigmatic exa

82 At certain junctures in development, gene transcription is coupled

83 r lineages diverged at the earliest critical junctures in evolution of adaptive immunity.

84 e cell identity and cell behavior at various junctures in the adipocyte lineage hierarchy are also co

85 date that B1 is needed for multiple critical junctures in the poxviral life cycle in a manner that is

86 minants that play a role at lymphoid-myeloid junctures, in particular transcription factors and cytok

87 g high accuracy for identifying key clinical junctures, including diagnosis, treatment, and early can

88 a cluster of five residues near the TM4-ECL2 juncture influenced orthosteric agonist efficacy.

89 sdermin over evolutionary time at speciation junctures, initially cleaving GSDME in fish, then GSDMA

90 Interestingly, slipping at this juncture is induced by TATA-binding protein and transcri

91 One particularly dramatic developmental juncture is the response of dicotyledonous seedlings to

92 At this juncture, it is critically important to have robust and

93 With this research field at a critical juncture, it is crucial to chart the course for the deve

94 At this exciting juncture, it is timely to review these new methodologica

95 the intrinsic cell death pathway at multiple junctures led to a significant inhibition of cardiomyocy

96 , summarizing the latest developments at the juncture of cardiology, oncology and haematology.

97 The SET domain of Set1 is located at the juncture of Cps50, Cps30, and the Cps60-Cps25 module, li

98 coding region of bcl-xL is generated by the juncture of exons II and III through a splicing reaction

99 P450 17A1 (CYP17A1) enzyme operates at a key juncture of human steroidogenesis, controlling the level

100 e adducts of the "open" type at the 6,6-ring juncture of Ih Sc3N@C80, differing greatly from the "clo

101 f the field of de novo protein design at the juncture of physics-based modeling approaches and AI.

102 The critical folding intermediates at the juncture of productive folding and the off-pathway aggre

103 molecule in fate determination at a critical juncture of T-cell differentiation.

104 d cDNA constructs terminating at or near the juncture of the betaalpha1 and beta1 domains: Residues 1

105 at SL1102 and SL1103 recognize a site at the juncture of the CCP1, CCP3, and vWF domains of FB.

106 Attention was paid to the juncture of the central prevertebral, perivascular, and

107 and then as a collar-like structure near the juncture of the nucleus and the elongating flagellum, bu

108 ies next to the conserved LPQG motif, at the juncture of the palm and fingers subdomains.

109 g triangular region in rodent located at the juncture of the PoS, PaS, retrosplenial cortex, and visu

110 d of NADPH meets the sterol substrate at the juncture of the two pockets.

111 extracellular amino acid substitution at the juncture of transmembrane helix 4 (TM4) and extracellula

112 ut the Mediterranean region at this critical juncture of Western civilization.

113 notyping implicates chimerism arising at the juncture of zygotic division, termed heterogonesis, as t

114 or for humoral immunity that acts at several junctures of B lineage maturation and effector cell diff

115 cells are negatively-regulated at different junctures of cancer-immunity cycle by this regulatory ki

116 ing rapid HDL remodeling and turnover at key junctures of cholesterol transport.

117 motactic response toward NAPL ganglia at the junctures of low- and high-permeability regions (i.e., m

118 iding theme formulated: Vulnerability at the junctures of systems, care processes and nurses' respons

119 dition occurs regioselectively at a 6,6-ring juncture on the surface of the icosahedrally (Ih) symmet

120 l group from o,o',o'',o'''-tetramethylbiaryl junctures, only slightly relaxes the biaryl twist angle

121 At critical junctures, oxidative damage to DNA requires the base exc

122 This juncture point appears to be one that is bypassed by tRN

123 nd protein export, being involved at a vital juncture point in their export pathways.

124 NA methylation alterations, defined distinct juncture points during aging, supporting a non-linear ag

125 ELF3 may act at more than one juncture, possibly posttranscriptionally.

126 r protocols to postacute care, each critical juncture presents unique challenges for the optimal care

127 th visible photoreceptor inner/outer segment juncture (PSJ).

128 ctivation and loading onto chromatin at this juncture remains unclear.

129 At this juncture, safety data on the use of VEGF-targeted therap

130 The juncture sequences suggest that the unessential A* (A st

131 observations collected during this critical juncture, show that women consistently reported a lower

132 by stable actor boundaries, other historical junctures, such as the end of the Cold War, exhibit far-

133 Thus, we have elucidated a key regulatory juncture that controls integrin recycling and also advan

134 However, at the current juncture, the American Diabetes Association's Standards

135 At the juncture, there is a critical requirement for clinical a

136 At this critical juncture, there is a need to synthesize the best evidenc

137 Indeed, the field is at a promising juncture to advance the neurobiological understanding of

138 ng partner RBP-J act at the basal/suprabasal juncture to induce spinous and down-regulate basal fate.

139 ace of O-GlcNAc research makes this a timely juncture to involve a wide array of scientists and new t

140 ed because I chose instinctively at multiple junctures to follow what proved to be propitious opportu

141 At certain evolutionary junctures, two or more mutations participating in the bu

142 all N25-ITS variants occurred at the +15/+16 juncture, unlike the +11/+12 juncture for the wild type

143 tand what occurs at the nuclear pore at this juncture, we have probed the role of the nucleoporin Nup

144 At this timely juncture, we provide a scientific rationale and three po

145 providers are uncomfortable at the clinical juncture where end-of-life care and organ donation inter

146 at the mosaic presently resides at a crucial juncture where relatively small changes in social condit

147 ependent proliferation, but reach a critical juncture where the requirement for IL-2 as a growth fact

148 ipheral transitional B-cell stage as a major juncture where transient autocrine IFNbeta expression by

149 immune response can be divided into specific junctures where critical decisions between tolerance and

150 ifically tailored to caregiver needs at this juncture, which support the transition into the caregive

151 At this juncture, while many questions remain unanswered, achiev

152 ng the visual complications at a preclinical juncture will offer an early therapeutic window for diag

153 past 20 years, and we are now at a critical juncture with regard to the clinical translation of the

154 nitial nucleus of the peripheral arm and its juncture with the membrane arm.

155 Biomedical research is at a critical juncture, with an aging population increasingly beset by

156 Yet, despite being at a pivotal juncture, with several randomized clinical trials maturi

157 Psychiatry is at an important juncture, with the current pharmacologically focused mod