ライフサイエンスコーパス: juvenile hormone

1 oid hormone ecdysone and the sesquiterpenoid juvenile hormone.

2 n with insect hormones, such as ecdysone and juvenile hormone.

3 r inhibited by diet, ovarian development, or juvenile hormone.

4 as a regulator of behavioral specialization: juvenile hormone.

5 oes by mimicking the action of their natural juvenile hormone.

6 hormones, 20-hydroxyecdysone (ecdysone) and juvenile hormone.

7 related roles of insulin-IGF-1 signaling and juvenile hormone.

8 als but the latter because of suppression by juvenile hormone.

9 arthropods that inhibit the biosynthesis of juvenile hormones.

10 ith the formation of sesquiterpenes, such as juvenile hormones.

11 We examine the role of juvenile hormone, 20-hydroxyecdysone, and insulin/insuli

12 Juvenile hormone, a crucial developmental regulator, act

13 FP) close to the transcription start site of juvenile hormone acid methyl transferase (JHAMT), a locu

14 m methyltransferase, Drosophila melanogaster Juvenile Hormone Acid O-Methyltransferase (DmJHAMT).

15 possibly mediated in part by an increase in juvenile hormone activity.

16 Juvenile hormone affected the expression of Vg and insul

17 aling event in turn enhances the efficacy of juvenile hormone, an age-related regulator of reproducti

18 developmental arrest with an application of juvenile hormone, an endocrine trigger known to terminat

19 Juvenile hormone, an important regulator of development

20 Juvenile hormone analog (JHA) insecticides are relativel

21 We observed that treatment with a juvenile hormone analog in the last nymphal instar stimu

22 In S2 cells, Ecd and the juvenile hormone analog methoprene exert opposite effect

23 reatment of the long-lived InR dwarfs with a juvenile hormone analog restores life expectancy toward

24 Application of hydroprene, a juvenile hormone analog, during the penultimate instar c

25 Juvenile hormone analogs (JHAs) are insecticides that pr

26 their fundamental behaviors to disseminate a juvenile hormone analogue (JHA) between resting and ovip

27 rmone titers and their regulation implicates juvenile hormone and ecdysone in the control of wing-mor

28 lated JHAMT and up-regulated CYP307A1 in the juvenile hormone and ecdysteroid pathways, respectively,

29 IIS) and target of rapamycin (TOR) pathways, juvenile hormone and ecdysteroid signaling, and epigenet

30 This includes genes related to juvenile hormone and insulin, two hormones shown previou

31 Adult ants use saliva to transfer juvenile hormone and other chemical signals to their lar

32 ns, which are inducible by the morphogenetic juvenile hormone and which constitute a significant prop

33 Our work suggests not only a new role for juvenile hormone and/or serotonin in Drosophila ovarian

34 tegrating reproductive maturity, signaled by juvenile hormone, and population density, signaled by CB

35 hat the interplay between insulin signaling, juvenile hormone, and vitellogenin regulates maternal ef

36 47b neurons requires a reproductive hormone, juvenile hormone, as well as its binding protein Methopr

37 ty to two ligand binding proteins, including juvenile hormone binding protein.

38 JH-binding protein, given the name mosquito juvenile hormone-binding protein (mJHBP), which circulat

39 dyw encodes a juvenile hormone-binding protein [4] that functions in n

40 he inhibitory effect of synthetic Ae-AS-C on juvenile hormone biosynthesis by the isolated corpora al

41 t characterized as a peptide that stimulated juvenile hormone biosynthesis in adult lepidopteran corp

42 e various functions, including inhibition of juvenile hormone biosynthesis in cockroaches and cricket

43 Farnesol is an intermediate in juvenile hormone biosynthesis, but is also produced by r

44 gene involved in an insect-specific step of juvenile hormone biosynthesis.

45 arch circadian clockwork; all members of the juvenile hormone biosynthetic pathway whose regulation s

46 We conclude that juvenile hormone deficiency, which results from InR sign

47 mRNA levels of Kruppel homolog 1 (Kr-h1), a juvenile hormone-dependent transcription factor that rep

48 roportion of total termite protein, suppress juvenile-hormone-dependent worker differentiation to the

49 Manduca sexta juvenile hormone diol kinase (JHDK) catalyzes the conver

50 The gene sequence of Manduca sexta juvenile hormone diol kinase (JHDK) codes for an enzyme

51 neuronal cultures, we show that ecdysone and juvenile hormone drive molecular and functional differen

52 , the insulin/IGF signaling pathway, and the juvenile hormone/ecdysteroid pathway.

53 Juvenile hormone epoxide hydrolase (JHEH) has attracted

54 BBB of a key hormone-degrading enzyme called juvenile hormone esterase (Jhe), and we show that this l

55 One pathway of this degradation is through juvenile hormone esterase (JHE), which cleaves the JH es

56 Juvenile hormone esterase (JHE; EC 3.1.1.1), which is in

57 Juvenile hormone esterase degrades juvenile hormone, whi

58 up by pericardial cells and native M. sexta juvenile hormone esterase in fat body tissue, where the

59 Circulating juvenile hormone esterase is removed from insect blood b

60 Binding assays showed that P29 bound juvenile hormone esterase more strongly than it did a mu

61 experiments, P29 bound injected recombinant juvenile hormone esterase taken up by pericardial cells

62 terase) and in an insect enzyme preparation (juvenile hormone esterase).

63 rize proteins involved in the degradation of juvenile hormone esterase, a pericardial cell cDNA phage

64 e et al., and down-regulated genes including juvenile hormone esterase-like protein et al.

65 cells to facilitate lysosomal degradation of juvenile hormone esterase.

66 structed and screened for proteins that bind juvenile hormone esterase.

67 tions in follicle formation were enhanced by juvenile hormone exposure and phenocopied by serotonin f

68 The presence of juvenile hormone had no effect on accumulation of either

69 ristoneura fumiferana is directly induced by juvenile hormone I (JH I), and the JH I induction is sup

70 ressed by physiologically relevant levels of juvenile hormone I (JH I).

71 Dramatically increased titer of the juvenile hormone III (JH III) is essential for the acqui

72 Juvenile hormone III (JH) plays a key role in regulating

73 The isoprenoids farnesol and juvenile hormone III (JH), metabolites of the cholestero

74 regulated in part by the positive effect of juvenile hormone III (JHIII) on gene expression for HMG-

75 -day-old males resulted in identification of juvenile hormone III bisepoxide and juvenile hormone III

76 ation of juvenile hormone III bisepoxide and juvenile hormone III in a ratio of 2.5:1.

77 the sesquiterpenoid methyl epoxyfarnesoate (juvenile hormone III) to Sf9 cells induces transcription

78 farnesoid X-activated receptor (farnesol or juvenile hormone III), or liver X receptor (22R-hydroxyc

79 ferator-activated receptor-alpha ligand, and juvenile hormone III, a farnesoid X-activated receptor a

80 The FXR activators, all-trans farnesol and juvenile hormone III, also accelerated epidermal barrier

81 1-epoxy-3,7,11-trimethyl-2,6-dodecadienoate [juvenile hormone III, JH III] with a turnover of 3-5 nmo

82 GPPS expression levels are regulated by juvenile hormone III, similar to other mevalonate pathwa

83 te (MF), the unepoxidised analogue of insect juvenile hormone-III (JH-III).

84 Without juvenile hormone, imaginal discs form and grow despite s

85 licaria Methyl farnesoate (MF) is the innate juvenile hormone in daphnids, which induces the producti

86 of amphibians that is equivalent to that of juvenile hormone in insect metamorphosis.

87 of farnesoic acid, an immediate precursor of juvenile hormone, indicating that the Ae-AS-C target is

88 e Carrier) transporter family member JhI-21 (Juvenile hormone Inducible-21), which is expressed in Dr

89 Juvenile hormone influences behaviour by changing cue re

90 lly, the results support the hypothesis that juvenile hormone is a pivotal hormone coordinating the d

91 We found that juvenile hormone is globally repressed, whereas ecdysone

92 transcription factor that plays key roles in juvenile hormone (JH) action] mRNA in the penultimate ny

93 r result in resistance to both methoprene, a juvenile hormone (JH) agonist insecticide, and JH.

94 In experiment 1, drones treated with the juvenile hormone (JH) analog methoprene started flying a

95 eptors is reversed by treating adults with a juvenile hormone (JH) analog.

96 is exposed to ecdysteroids in the absence of juvenile hormone (JH) and becomes committed to pupal dif

97 e neuronal CoREST corepressor and changes in juvenile hormone (JH) and ecdysone signaling during the

98 Two key hormones, juvenile hormone (JH) and ecdysteroids (20-hydroxyecdyso

99 Metamorphosis in insects is regulated by juvenile hormone (JH) and ecdysteroids.

100 Our recent studies identified juvenile hormone (JH) and nutrition as the two key signa

101 on the disappearance of the antimetamorphic juvenile hormone (JH) and the transcription factors Krup

102 Here, the complex crosstalk between juvenile hormone (JH) and the two nutrient sensors insul

103 Ecdysone and juvenile hormone (JH) are important regulators of insect

104 mporally directed manipulations, we identify juvenile hormone (JH) as an anticipatory endocrine signa

105 hort-day conditions by the downregulation of juvenile hormone (JH) biosynthesis in the corpus allatum

106 Juvenile hormone (JH) biosynthesis in the corpus allatum

107 To gain insights into how juvenile hormone (JH) came to regulate insect metamorpho

108 Juvenile hormone (JH) controls the development and repro

109 Juvenile hormone (JH) coordinates timing of female repro

110 ol kinase (JHDK) catalyzes the conversion of juvenile hormone (JH) diol to JH diol phosphate.

111 lay of mRNA technique we discovered that the juvenile hormone (JH) esterase gene (Cfjhe) from Chorist

112 Juvenile hormone (JH) governs a great diversity of proce

113 Juvenile hormone (JH) has been implicated in many develo

114 Application of a high dose of juvenile hormone (JH) III or its mimics (JHM) to Drosoph

115 component, ipsdienol, de novo in response to juvenile hormone (JH) III.

116 histone deacetylase (HDAC) inhibitor, mimics juvenile hormone (JH) in inducing JH response genes (e.g

117 ar receptor mediating the genomic actions of juvenile hormone (JH) in insects, the identity of the re

118 se of its critical role in the regulation of juvenile hormone (JH) in insects.

119 To elucidate the role of juvenile hormone (JH) in metamorphosis of Drosophila mel

120 The role of juvenile hormone (JH) in regulating the timing and natur

121 relatively little is known about the role of juvenile hormone (JH) in the control of female reproduct

122 is review explores the roles of ecdysone and juvenile hormone (JH) in the evolution of complete metam

123 In fruit flies, juvenile hormone (JH) induces intestinal stem cell (ISC)

124 Juvenile hormone (JH) is a key insect developmental horm

125 Juvenile hormone (JH) is a key regulator of insect devel

126 The synthesis of juvenile hormone (JH) is an attractive target for contro

127 Juvenile hormone (JH) is an important regulator of both

128 Juvenile hormone (JH) is an insect hormone containing an

129 Studies in eusocial insects have shown that juvenile hormone (JH) is associated with division of lab

130 Juvenile hormone (JH) is critical for achieving reproduc

131 Juvenile hormone (JH) is critical for multiple aspects o

132 nsects, increasing evidence has demonstrated juvenile hormone (JH) is involved in regulating adult re

133 the endocrine glands that produce the insect juvenile hormone (JH) is most closely related to P450 pr

134 Juvenile hormone (JH) is synthesized by the corpora alla

135 The sesquiterpenoid juvenile hormone (JH) is vital to insect development and

136 l for courtship memory through regulation of juvenile hormone (JH) levels in adult males.

137 tion of a supernumerary nymphal stage with a juvenile hormone (JH) mimic prevented the disappearance

138 Juvenile hormone (JH) plays crucial roles in many aspect

139 Juvenile hormone (JH) plays vital roles in insect reprod

140 Juvenile hormone (JH) prevents these changes in earlier

141 ons as an obligatory allatotropin to promote juvenile hormone (JH) production and reproduction.

142 Juvenile hormone (JH) receptor, Methoprene-tolerant (Met

143 Juvenile hormone (JH) regulates a wide variety of biolog

144 Juvenile hormone (JH) regulates insect development by a

145 om fourth instar larvae with high endogenous juvenile hormone (JH) showed a 10-fold higher sensitivit

146 Juvenile hormone (JH) signaling in the polyphenic strain

147 Despite longstanding efforts, the juvenile hormone (JH) signaling pathway remains unknown.

148 Juvenile hormone (JH) signalling, via its receptor Metho

149 ely induced by sex differentiation genes and juvenile hormone (JH) signalling.

150 CA), the latter being solely responsible for juvenile hormone (JH) synthesis and release.

151 s rising, and this increase was prevented by juvenile hormone (JH) that prevented adult development.

152 Once critical weight is reached, juvenile hormone (JH) titers decline, resulting in the r

153 measured the time to initiate metamorphosis, juvenile hormone (JH) titers, and the abundance of trans

154 an controls and receiving aggression reduces juvenile hormone (JH) titers.

155 lopmental transition that is induced by high juvenile hormone (JH) titers.

156 nsect hormones, 20-hydroxyecdysone (20E) and juvenile hormone (JH) to elicit an important physiologic

157 represses expression of enzymes that degrade juvenile hormone (JH), a hormone elevated upon reprogram

158 Treatment with the insect hormone juvenile hormone (JH), a key regulator of metamorphosis,

159 The molecular action of juvenile hormone (JH), a regulator of vital importance t

160 ycles, which are in turn driven by cycles of juvenile hormone (JH), can be eliminated by application

161 An epoxidated form of MF, known as juvenile hormone (JH), controls metamorphosis and stimul

162 in, vitellogenin (Vg), and endocrine factor, juvenile hormone (JH), functions as a pacemaker driving

163 lated but were largely related to effects of juvenile hormone (JH), suggesting that the increase in J

164 ster is attributable to the endocrine signal juvenile hormone (JH), which promotes the development of

165 pleiotropic proteins that bind and transport juvenile hormone (JH)-a key regulator of insect developm

166 portant status quo role in the regulation of juvenile hormone (JH)-dependent caste differentiation.

167 ed in mediating vitellogenin (Vg) uptake and juvenile hormone (JH)-regulated remodeling of follicular

168 The promoters of three juvenile hormone (JH)-sensitive, and one JH-insensitive

169 ponses of the Lepidoptera and the Diptera to juvenile hormone (JH).

170 is is under the dual control of ecdysone and juvenile hormone (JH).

171 ydroxyecdysone (20E) and the sesquiterpenoid juvenile hormone (JH).

172 cally transmitted throughout the organism by juvenile hormone (JH).

173 ark conditions, starvation, temperature, and juvenile hormone (JH).

174 Juvenile hormones (JH) are a class of regulatory sesquit

175 or identification and quantitation of insect juvenile hormones (JH) has been developed using capillar

176 is of high specific activity insect [10-(3)H]juvenile hormones (JH) I, II, and III which affords both

177 Juvenile hormones (JH) regulate a wide variety of develo

178 Juvenile hormones (JH), a sesquiterpenoid group of ligan

179 o hormonal systems, the ecdysteroids and the juvenile hormones (JH), which function in both embryonic

180 affinity analogs of the natural lepidopteran juvenile hormones, JH I and II [epoxy[3H]bishomofarnesyl

181 that this localization governs the level of juvenile hormone (JH3) entering the brain.

182 Juvenile hormones (JHs) are sesquiterpenoids synthesized

183 Juvenile hormones (JHs) control insect metamorphosis and

184 h as retinoic acids (RAs) in vertebrates and juvenile hormones (JHs) in invertebrates, facilitate mul

185 ging), but not affected by dominance rank or juvenile hormone known to influence physiology and behav

186 nd drives age-related functional decline via juvenile hormone-lipid transfer protein axis and germlin

187 We conclude that juvenile hormone mediated a positive feedback system tha

188 mating was induced by topical application of juvenile hormone, methoprene, or fenoxycarb.

189 Early treatments with juvenile hormone mimic (JHm) appear to repress extension

190 vents could be prevented by application of a juvenile hormone mimic (JHM).

191 The juvenile hormone mimic, pyriproxyfen is a suppressor of

192 Topical application of a juvenile-hormone mimic to the flight-capable morph cause

193 domatuic acid, juvabione, and related insect juvenile hormone mimics.

194 Although the hemolymph titer of juvenile hormone normally decreases to low levels early

195 Loss of juvenile hormone O-methyltransferase, a key enzyme in ca

196 olactin (PRL) is widely considered to be the juvenile hormone of anuran tadpoles and to counteract th

197 ormal schedule, and the inhibitory action of juvenile hormone on this checkpoint.

198 f insects studied, they act as inhibitors of juvenile hormone production in only some groups.

199 urohormonal pathway linking clock neurons to juvenile hormone production in the CA, ultimately induci

200 Mimicking one feature of quiescence, reduced juvenile hormone production, enhanced GSC longevity in n

201 onse that ultimately leads to a cessation of juvenile hormone production.

202 The insect juvenile hormone receptor is a basic helix-loop-helix (b

203 the role of GPCRs in insect reproduction and juvenile hormone-regulated Vg uptake, we performed a com

204 Juvenile hormone regulation of Vg synthesis has been kno

205 We show that a mutation in the juvenile hormone-regulatory pathway in Manduca sexta ena

206 A juvenile hormone response element (JHRE) has been identi

207 at 4 element and is designated as a putative juvenile hormone response element (JHRE).

208 Insulin and juvenile hormone signaling direct entry of the mosquito

209 storage proteins are implicated in silencing juvenile hormone signaling, which is a prerequisite for

210 homolog 1 (Kr-h1), one of the key players in juvenile hormone signaling.

211 ests that this decision is regulated through juvenile hormone signaling.

212 For example, we conclude that juvenile hormone signalling evolved with the emergence o

213 h inhibitory effects on visceral muscles and juvenile hormone synthesis.

214 one function in insects is the inhibition of juvenile hormone synthesis.

215 racts from mated males contained 3-fold more juvenile hormone than did extracts from virgins.

216 l cells of the ring gland, which produce the juvenile hormone that controls progression through devel

217 udy identifies a direct neural substrate for juvenile hormone that permits coordination of courtship

218 tar, eye disc development begins even if the juvenile hormone titer is artificially maintained at hig

219 e, the HDAC genes showed the same profile of Juvenile Hormone titers-previous reported-whereas the HA

220 ion on allatectomized (CAX) larvae that lack juvenile hormone to impose the critical weight checkpoin

221 ynthesis and degradation of ecdysteroids and juvenile hormones to the metabolism of foreign chemicals

222 Starvation and juvenile hormone treatments allowed the separation of in

223 insect growth regulator mimicking an insect juvenile hormone which results in adult mosquito emergen

224 Juvenile hormone esterase degrades juvenile hormone, which acts in conjunction with ecdyste

225 Mating releases juvenile hormone, which desensitizes Or47b olfactory neu

226 insect corpora allata, produce precursors of juvenile hormone with putatively similar functions.