ライフサイエンスコーパス: key component

1 lipid rafts, which include sphingolipids as key components.

2 assumed to work (causal assumptions) and its key components.

3 uptions can halt power production and damage key components.

4 scribe newly developed approaches to dissect key components.

5 to define the physiological significance of key components and informing targeted functional gene ma

6 ideline recommendations with respect to each key component, and provides our preferred diagnostic pat

7 The CCR4-NOT1 complex contains two key components, CCR4 and CAF1, which are the main cytopl

8 which suggested that GK-15 may be one of the key components contributing to the umami taste in tempeh

9 rt, regulates ciliary trafficking of KAP3, a key component for functional kinesin-2.

10 We conclude that a capacity for empathy is a key component for sustaining cooperation in societies.

11 llular localization of AGR2 is emerging as a key component for understanding the role of AGR2 as a pr

12 ings, further research will help to identify key components for contextualizing and implementing such

13 studied to understand the functions of these key components for structural formation and mineralizati

14 he physiological determinants of NUE and its key components hampers the design of more effective bree

15 As such, direct observation of three key components, i.e., metal center, support and substrat

16 As the key component in ASSLBs, solid-state electrolytes (SSEs)

17 A key component in both methods is the use of the quantum

18 Orbital fibroblasts are a key component in GO pathogenesis, which includes inflamm

19 fully known, mitochondrial dysfunction is a key component in methamphetamine neuropathology.

20 ent to human health and the environment is a key component in natural resource management.

21 tor of TORC1 and demonstrate that TORC1 is a key component in P signaling in Chlamydomonas.

22 NR2E3 is a key component in p53 activation by regulating a long non

23 opium chelate-conjugated probe, which is the key component in sensing the hydrophobic regions exposed

24 e mitochondrial dysfunction is emerging as a key component in the etiology of T2DM.

25 acoronaviruses in lineages A and C, and be a key component in the evolution of SARS-CoV-2 with this s

26 Vector control has been a key component in the fight against malaria for decades,

27 domains of PSD-95 have been shown to be the key component in the formation of channel clusters.

28 As mucus hyperexpression is a key component in the initiation and perpetuation of airw

29 glycosylation of alpha-dystroglycan (DG), a key component in the link between the cytoskeleton and t

30 s that learning the migratory direction is a key component in the navigational system of naive bats i

31 Obesity-induced chronic inflammation is a key component in the pathogenesis of nonalcoholic fatty

32 in systems of (self-)propelled agents and a key component in the structuring of many biological syst

33 armacological therapies are recommended as a key component in the treatment of attention-deficit hype

34 iple models we find that mutations in APC, a key component in the Wnt signalling pathway, can bias ne

35 factors for the induction of interferons, a key component in vertebrate innate immunity.

36 ave been invaluable to elucidate many of the key components in B-cell tolerance; however, translation

37 with kinases and transcription factors, are key components in cellular signalling networks.

38 or environmental aspects and have emerged as key components in determining cancer cell metabolism.

39 Fungi are key components in global biogeochemical cycles, play imp

40 Together, our findings define key components in HBV cccDNA formation.

41 Plasma biomarkers, key components in phenotype identification, currently la

42 gnaling by decreasing the phosphorylation of key components in the canonical T-cell signaling pathway

43 Key components in the development of QOL instruments inc

44 Metabolic modeling and machine learning are key components in the emerging next generation of system

45 erous membrane-associated proteins, they are key components in the establishment of organelle identit

46 While acknowledged as key components in the formation of new particles in the

47 Interferons are key components in the innate immunity and play crucial r

48 One of the key components in the photopolymerization processes is t

49 g (VSRs) that interfere with the function of key components in the silencing pathway.

50 pmental transition, including genes encoding key components in the TGF-beta, GDNF, AKT, and JAK-STAT

51 To identify the key component involved in storage lipid biosynthesis, tw

52 A key component is Social Value Orientation (SVO), which q

53 A key component is the Cyt toxin, which synergizes the act

54 ed red blood cell membrane with two inserted key components: melittin and oleyloxyethyl phosphorylcho

55 To gain insight into key components necessary for KRAS signal transduction at

56 osis function of the NDR/LATS kinase Cbk1, a key component of "hippo" signaling that induces mother-d

57 a resources worldwide and collectively are a key component of a global infrastructure of interconnect

58 able health risk factors and be considered a key component of a healthy lifestyle.

59 Thus, our data identify FSP1 as a key component of a non-mitochondrial CoQ antioxidant sys

60 Background Hyperemia is a key component of acute myocarditis (AM).

61 Seed mass is a key component of adaptation in plants and a determinant

62 between experienced and predicted reward, a key component of adaptive behaviour.

63 Tropospheric ozone (O(3)) is a key component of air pollution and an important anthropo

64 sea ice and dark melted surface areas is the key component of albedo feedback.

65 ected that enantiomeric fidelity has to be a key component of all of the steps in translation.

66 A key component of antiretroviral therapy (ART) for HIV pa

67 tors (PIs), such as darunavir (DRV), are the key component of antiretroviral therapy.

68 The hydroxide anion exchange polymer is a key component of any solid polymer electrolyte device th

69 ow that aberrant mitochondrial function is a key component of AOA1 pathology.

70 y reported that the polysaccharide chitin, a key component of arthropod exoskeletons and fungal cell

71 N-Acetylglucosamine is a key component of bacterial and fungal cell walls and of

72 Vigilance is a key component of behavioral inhibition, a personality tr

73 Strong currents are a key component of benthic habitats by supplying food and

74 Environmental DNA analysis has emerged as a key component of biodiversity and environmental monitori

75 es different approaches to parallelising the key component of biological and immune system models wit

76 Dissolved organic matter (DOM) represents a key component of carbon (C) cycling in freshwater ecosys

77 CAV1, a key component of caveolae, interacted with strumpellin i

78 tal fast-spiking interneuron population as a key component of compulsive ethanol consumption.

79 Methyl CpG binding protein 2 (MeCP2) is a key component of constitutive heterochromatin, which is

80 he most abundant anion in blood plasma, is a key component of Cp catalysis.

81 expresses a fusion protein of granzyme B, a key component of cytotoxic granules involved in T cell-m

82 that hypotheses in which 2-thiouridine was a key component of early RNA sequences are within the boun

83 Adaptation is a key component of efficient coding in sensory neurons.

84 ation of succinate dehydrogenase A (SDHA), a key component of electron transport chain complex (ETC)

85 The hippocampus is a key component of emotional and memory circuits and is br

86 Although pyrazinamide (PZA) is a key component of first- and second-line tuberculosis tre

87 t vertical WSe(2) Schottky diodes could be a key component of future high frequency electronics in th

88 haliana seeds, endosperm cell expansion is a key component of germination.

89 A key component of gingival health is the regulation of th

90 Positive animal emotion (affect) is a key component of good animal welfare [1] and plays an im

91 Handwashing is a key component of guidance to reduce transmission of the

92 Physical capability, a key component of healthy aging, is associated with cardi

93 Phytochelatin synthase (PCS) is a key component of heavy metal detoxification in plants.

94 ffects how we process binocular disparity, a key component of human depth perception.

95 ayers to layers 2/3 pyramidal neurons as the key component of hyperexcitable circuitry.

96 ed as a growth factor for T cells and thus a key component of immune activation.

97 ram evaluation and outcome measurement are a key component of implementation.

98 Alpha synuclein (alphaS) oligomers are a key component of Lewy bodies implicated in Parkinson's d

99 Communicating species identity is a key component of many animal signals.

100 The portal protein is a key component of many double-stranded DNA viruses, gover

101 e previously identified Argonaute 1 (AGO1; a key component of microRNA-induced silencing complex) as

102 In summary, mtACP, as a key component of mitochondrial fatty acid biosynthesis,

103 Importantly, the sense of touch is a key component of motor function.

104 Thus, radiotherapy is becoming a key component of multimodal therapy for many stages of p

105 Action potentials are a key component of neuronal communication and their precis

106 els have demonstrated that nitric oxide is a key component of neurovascular coupling; this has yet to

107 e conclude that macrophage-derived Vegf is a key component of NMJ recovery after injury.

108 Soluble guanylyl cyclase (sGC) is a key component of NO-cGMP signaling in mammals.

109 entral to the origin of life because it is a key component of nucleotides in genetic molecules, phosp

110 tinal stem cell (ISC) proliferation and is a key component of organoid growth media yet is dispensabl

111 tracellular reactive oxygen species (ROS), a key component of oxaliplatin cytotoxicity, was significa

112 l protein involved in phase separation and a key component of P granules.

113 RNA-splicing and homeostasis regulator and a key component of p53-mediated tumor suppression.

114 es target the HA surface protein, which is a key component of pandemic influenza viruses.

115 mic era, genomic medicine interventions as a key component of personalized medicine and tailored-made

116 the administration of photosensitizers is a key component of photodynamic therapy, exogenous phototh

117 Phytochemical traits are a key component of plant defense theory.

118 Prediction of disease risk is a key component of precision medicine.

119 Epidemiology is also a key component of preventive medicine and public health.

120 ports current recommendations that VMMC is a key component of programs to reduce HIV incidence.

121 hotonic Bell-state measurements, which are a key component of quantum repeaters.

122 RC2 drives formation of RNA-DNA hybrids, the key component of R-loops, from RNA and dsDNA.

123 wo drivers suggests that connectivity is the key component of riverine fish geographic range sizes, i

124 Surveillance, a key component of screwworm control programs, utilizes tr

125 A key component of seed germination is the interplay of me

126 domain and a hypervariable C terminus, as a key component of self-recognition.

127 nverts UDP-glucose to UDP-glucuronic acid, a key component of specific proteoglycans and glycolipids.

128 Leukocyte trafficking is a key component of steady-state tissue homing and in mount

129 ase DDX3 (DEAD-box helicase 3 X-linked) is a key component of stress granules (SG) and is postulated

130 Inhibition of translation is a key component of such cellular stress responses and moun

131 Rifamycin antibiotics are a key component of TB therapy and a common source of drug-

132 3 (ELF3)(4,7), a large scaffold protein and key component of temperature sensing; ELF4, a small alph

133 Soil organisms, including earthworms, are a key component of terrestrial ecosystems.

134 te innovation that has been proposed to be a key component of the 'new head', which imbued vertebrate

135 k reveals that actin reduction by MsrB2 is a key component of the abscission checkpoint that favors F

136 Antarctic krill (Euphausia superba) are a key component of the Antarctic food web with considerabl

137 rroptocide is an inhibitor of thioredoxin, a key component of the antioxidant system in the cell.

138 phagy-related protein 4 homolog B (ATG4B), a key component of the autophagy machinery, was demonstrat

139 elial cell adhesion molecule E-selectin is a key component of the bone marrow hematopoietic stem cell

140 -coding in ventromedial prefrontal cortex, a key component of the brain's reward system.

141 Ventrolateral area 44 (a key component of the Broca's language production region

142 t down-regulation of the POP2 deadenylase, a key component of the CCR4-NOT deadenylation complex, alt

143 Urodynamic studies are a key component of the clinical evaluation of lower urinar

144 Fibrinogen is a key component of the coagulation cascade, and variation

145 ave identified a novel protein, BB0326, as a key component of the collar.

146 t statistical tools either fail to capture a key component of the cue-phenology relationship, or the

147 ation and is tightly regulated by SLC7A11, a key component of the cystine-glutamate antiporter.

148 bilities, data science is quickly becoming a key component of the drug discovery pipeline.

149 st that the H3K36 methylation machinery is a key component of the epigenetic maintenance system in hu

150 d through direct phosphorylation of Exo70, a key component of the exocyst complex.

151 lial hyaluronan is a previously unrecognized key component of the extracelluar matrix that is require

152 Hyaluronan (HA) is a key component of the extracellular matrix.

153 A key component of the flexibility and complexity of the b

154 Paxillin (PXN), a key component of the focal adhesion complex, has been as

155 ss the total lake CH(4) flux, representing a key component of the global CH(4) budget.

156 The glomerular basement membrane (GBM) is a key component of the glomerular capillary wall and is es

157 Interleukin-6 (IL-6) has emerged as a key component of the immune response to SARS-CoV-2, such

158 s a robust downregulation of neuroligin-2, a key component of the inhibitory synapse, in the NAc that

159 IFN-beta is a key component of the innate immune response to viral inf

160 units packed into well-defined helices, is a key component of the iron regulatory system in the brain

161 of the mediodorsal thalamus (MD), which is a key component of the limbic cortico-basal ganglia-thalam

162 e-associated membrane protein 4 (VAMP4) as a key component of the machinery that maintains these Ca(2

163 e amygdala to the orbitofrontal cortex and a key component of the medial temporal lobe-prefrontal cor

164 naling is also a target for decanoic acid, a key component of the medium-chain triglyceride (MCT) ket

165 tocytes regulates the expression of STAG3, a key component of the meiotic cohesin complex, via a non-

166 PMEL encodes a key component of the melanosome, the organelle essential

167 Focal adhesion kinase (FAK) is a key component of the membrane proximal signaling layer i

168 specifically binds to and inhibits Drosha, a key component of the microprocessor complex required for

169 Depletion of betaII-spectrin, a key component of the MPS, suppresses retrograde signalin

170 ed the hypothesis that TBK1 phosphorylates a key component of the mTOR complex 1 (mTORC1), Raptor.

171 Olfaction is a key component of the multimodal approach used by mosquit

172 Here, we identify AKAP6 as key component of the nuclear envelope MTOC.

173 The nuclear lamina protein lamin A/C is a key component of the nuclear envelope.

174 2beta, a SNF-2-like nucleosome remodeler and key component of the nucleosome remodeling and histone d

175 SuPAR may be a key component of the pathophysiology of AKI in COVID-19.

176 ructural plasticity of dendritic spines is a key component of the refinement of synaptic connections

177 iated with the genetic variation in CLSY1, a key component of the RNA-directed DNA-methylation machin

178 Argonaute-2 (Ago2) is a key component of the RNA-induced silencing complex that

179 ular nucleus of the hypothalamus (PVH) are a key component of the satiety response; activation of the

180 and tissue homeostasis, was identified as a key component of the signalosome.

181 These findings identify TRIB3 as a key component of the spliceosome, whose repression contr

182 ontrol of multiconfigurational behavior as a key component of the stability of the complex.

183 Here we show that Arid1a, a key component of the SWI/SNF chromatin remodeling comple

184 The gene cagY encodes for a key component of the T4SS and can undergo gene rearrange

185 The RNA helicase eIF4A1 is a key component of the translation initiation machinery an

186 Cancer associated fibroblasts (CAFs) are a key component of the tumor microenvironment.

187 Cancer-associated fibroblasts (CAFs) are a key component of the tumour microenvironment with divers

188 ated valosin-containing protein (Vcp/p97), a key component of the ubiquitin-proteasome system.

189 sitol-requiring enzyme 1alpha (IRE1alpha), a key component of the unfolded protein response in mammal

190 -like endoplasmic reticulum kinase (PERK), a key component of the unfolded protein response.

191 nfection (LTBI) screening and treatment is a key component of the World Health Organization (WHO) End

192 ansport of tubulin to the flagella tips as a key component of their length control.

193 that protein disulphide isomerase provides a key component of these barriers, mediating contact repul

194 is the first-line treatment for insomnia; a key component of this intervention is restriction of sle

195 AD(P)H dehydrogenase-like complex (NDH) is a key component of this pathway in most oxygenic photosynt

196 the extracellular protein reelin (RELN) as a key component of this process.

197 Yet, a key component of this puzzle-the contributions of indivi

198 or pharmacological inhibition of IFN-beta, a key component of type I IFN mechanisms to address its ro

199 t antiviral response in the infected cell, a key component of which is the expression of genes encodi

200 ough complex biological microenvironments, a key component of which is the extracellular matrix (ECM)

201 n major land plant lineages and are probably key components of a genetic network through which terres

202 soils, it is surprising that so many of the key components of a soil community develop already by th

203 l provides a unique platform for elucidating key components of adolescent brain function.

204 Thus, HNF4 paralogs are key components of an intestinal transcription factor net

205 ve search outputs and a useful help menu are key components of atSNP Search.

206 Rho of Plants (ROP) G-proteins are key components of cell polarization processes in plant d

207 However, the key components of coal that drive lung cancer risk have

208 Overall, our approach identified key components of cognitive mechanisms for incorporating

209 ntify two Tmod isoforms, Tmod1 and Tmod3, as key components of contractile stress fibers in non-muscl

210 used to various effector domains (SAVED) are key components of cyclic oligonucleotide-based antiphage

211 This Review assesses all key components of diagnostic clinical pathways recommend

212 In return, ACO4 and other key components of ethylene signaling negatively regulate

213 We systematically identify key components of genetic associations and the contribut

214 els of neonatal acute phase proteins (APPs), key components of innate immune function, measured in ne

215 Calcium-regulated protein kinases are key components of intracellular signaling in plants that

216 At nonsaturating doses, IL-10 did not induce key components of its gene expression program, which may

217 fect in information retrieval, making up the key components of Knowledge Organization Systems (KOSs)

218 Spin waves may constitute key components of low-power spintronic devices.

219 cific chemical and mechanical properties are key components of many biomaterials used for regenerativ

220 tection of photoreduction processes that are key components of many photocatalytic reaction schemes.

221 tion factors that regulate the expression of key components of metabolic pathways.

222 arth-based, and intermetallic compounds) are key components of modern technological applications.

223 ibitors; therefore, better understandings of key components of mutant EGFR (mtEGFR) signaling are req

224 id 25 mg significantly improved fibrosis and key components of NASH disease activity among patients w

225 of these have previously been implicated in key components of neural signalling (specifically an ion

226 and their microbiomes are now recognized as key components of plant health, but how to steer those m

227 ther also spatially define the activation of key components of regeneration, such as the transcriptio

228 Key components of RNA degradation machineries, including

229 Actin filaments (F-actin) are key components of sarcomeres, the basic contractile unit

230 ydrate loading, and avoidance of fasting are key components of successful colorectal ERAS and surgica

231 The key components of such predictive algorithms are the fea

232 g cancer models lacking SMARCA4 and SMARCA2, key components of SWI/SNF chromatin remodeling complexes

233 This study explores two key components of systems interventions: (1) steering co

234 ess.Objectives: We examined the function and key components of the alternative complement pathway in

235 ion in expression of positive regulators and key components of the AMPK pathway, autophagy, proteasom

236 To explore the molecular characteristics and key components of the aortic microenvironment, where the

237 layed peptide/MHCII complexes constitute two key components of the B-cell machinery to sense signals

238 sitol (PI) acts as a common lipid anchor for key components of the cell wall, including the glycolipi

239 of kinases and their downstream targets are key components of the cellular machinery that ensures th

240 Cohesin SA1 (STAG1) and SA2 (STAG2) are key components of the cohesin complex.

241 n early divergent microbial eukaryote, lacks key components of the conventional DNA damage-induced G2

242 tein polymers composed of tubulin dimers are key components of the cytoskeleton.

243 Airway macrophages (AMs) are key components of the defense of the airways and are imp

244 This work uncovers key components of the dynamic relationships between RET

245 E1alpha perturbation inhibited expression of key components of the endoplasmic reticulum-associated d

246 r activation in breast cancer highlights the key components of the estrogen receptor complex alongsid

247 We identified key components of the genetic network that controls bran

248 We found that Mt2 specifically cleaved the key components of the hepcidin-induction pathway, includ

249 ayers in human NAFLD and which may determine key components of the heritability of distinctive diseas

250 function results in abnormal PC dynamics of key components of the Hh signaling pathway and leads to

251 dual role as targets of viral infection and key components of the host response.

252 nse peptides (HDPs), short peptides that are key components of the innate immune response, exhibit an

253 Besides finding key components of the interferon signaling pathway, we d

254 ts in BD participants, ketamine also impacts key components of the KYN pathway.

255 by NADPH oxidases (Noxes), such as Nox2, are key components of the macrophage response to invading pa

256 elated scaffold proteins, TKS5 and TKS4, are key components of the mechanism of invadopodia assembly.

257 The most investigated nutrients are key components of the Mediterranean diets such as fruits

258 actions between astrocytes and Agrp neurons (key components of the melanocortin system), we performed

259 ures of NASH, GAN DIO-NASH mice demonstrated key components of the metabolic syndrome, including obes

260 t it was a transcriptional activator of many key components of the MHC-I pathway, including immunopro

261 dd45gamma reduction impaired the activity of key components of the mitogen-activated protein kinase (

262 with MMSE, along with the identification of key components of the MK pathway that drive this associa

263 ity of synthetic EVs to isolate and identify key components of the molecular handshake between EVs an

264 Here, we delineate several key components of the molecular pathway that links confo

265 amycin to the molecular characterizations of key components of the mTORC signalling network with an e

266 d molecular genetic experiments, we identify key components of the non-ionotropic NMDAR signaling pat

267 rved a reduction in a subset of 8, including key components of the nuclear pore complex scaffold and

268 Adipocytes are key components of the OvCa microenvironment and have bee

269 ers and there are multiple efforts to target key components of the pathway for disease intervention.

270 Key components of the photosynthesis gene regulatory net

271 Three key components of the roadmap are: support and improve t

272 ets leads to a decrease in the expression of key components of the secretory machinery of beta-cells,

273 Although key components of the SHH pathway are well-known, we hyp

274 Antibodies are key components of the skin immune barrier, and antibodie

275 tissues of PEX patients together with other key components of the STRA6 receptor-driven retinoic aci

276 Glomerular endothelial cells are key components of the structure and function of the glom

277 hormone signaling through the modulation of key components of the transduction pathways.

278 Mutations in genes encoding key components of the transport machinery, including mot

279 upstream regulators (FOXO1, FOXO3, NFKB1A), key components of the ubiquitin proteasome pathway (FBXO

280 tor 2alpha subunit and the splicing of Xbp1, key components of the UPR.

281 Motor neurons (MNs), key components of these circuits, project their axons fr

282 Alterations in one or more key components of this axis (CDKs, cyclins, CDK inhibito

283 oxia-inducible factor (HIF) pathway, and the key components of this pathway are thought to be highly

284 olysaccharide synthesis and export; however, key components of this pathway have remained unidentifie

285 Key components of this pathway were collecting patient-r

286 mice in the baseline pulmonary expression of key components of TLR4-NFkappaB signaling, or in the LPS

287 and hepatitis A and B vaccinations should be key components of viral hepatitis prevention.

288 Bacteria and fungi are key components of virtually all natural habitats, yet th

289 sponses, and how this alteration affects the key components of virus dynamics such as infection rate,

290 ygen evolution reaction (OER) activities are key components of wearable metal-air batteries.

291 tiation in liposarcoma by targeting multiple key components (PDGFRbeta, SMAD4, and YAP1) in several o

292 ontroller of endosomal recycling [4-6], as a key component regulating core planar polarity protein lo

293 Several key components such as clinical prediction tools, risk s

294 vivo platforms that enable identification of key components that promote immune cell recruitment to t

295 Mass balance analysis of ice sheets is a key component to understand the effects of global warmin

296 ular condensates in cells, which concentrate key components to achieve high efficient degradation of

297 Antibodies are key components to prevent and treat Ebola virus disease

298 neated the contributions of a minimal set of key components via computational and experimental refact

299 DNA-PK is a key component within the DNA damage response, as it is r

300 molecular networks, likely with peptides as key components, would have played in life's origin.