ライフサイエンスコーパス: kinase cascade

1 regulatory input provided by the Hippo-Warts kinase cascade.

2 in Hippo and Warts, two kinases in the Hippo kinase cascade.

3 phorylation status at multiple levels of the kinase cascade.

4 timulates AP1 activity by activating the MAP kinase cascade.

5 f MT growth are coordinated by the DLK-1 MAP kinase cascade.

6 nsduction from the cell membrane to its core kinase cascade.

7 t least in part through a kinase-phosphatase-kinase cascade.

8 but apparently not regulated by the YDA MAP kinase cascade.

9 which mediates the activation of the Akt-TOR kinase cascade.

10 thway rather than the canonical three-tiered kinase cascade.

11 ein CEBP-1, a downstream factor of the DLK-1 kinase cascade.

12 a canonical heterotrimeric G protein and MAP kinase cascade.

13 rylation of SSK1 and activating the HOG1 MAP kinase cascade.

14 ensed upstream and relayed to Hog1 through a kinase cascade.

15 ssion led to the suppression of the MKK4/JNK kinase cascade.

16 s4 response regulator, which activates a MAP kinase cascade.

17 ulated via MrpC phosphorylation by a Ser/Thr kinase cascade.

18 receptors to bind FGF21 and activate the MAP kinase cascade.

19 ependent signaling pathways, such as the Erk kinase cascade.

20 h and homeostasis through a central MST-LATS kinase cascade.

21 -forward kinase cascades typified by the MAP kinase cascade.

22 smolarity glycerol mitogen-activated protein kinase cascade.

23 bsequent activation of the Raf-MEK-ERK (MAP) kinase cascade.

24 e the firm adhesion of neutrophils via a MAP-kinase cascade.

25 e MEK1, suggesting its dependence on the MAP kinase cascade.

26 tion of the p42/44 mitogen-activated protein kinase cascade.

27 and thereby amplifies signaling through the kinase cascade.

28 nd cellular location, also activates the MAP kinase cascade.

29 nal-related kinase/mitogen-activated protein kinase cascade.

30 hat regulate this powerful positive feedback kinase cascade.

31 he Mst11-Mst7-Pmk1 mitogen-activated protein kinase cascade.

32 ycerol (HOG) mitogen-activated protein (MAP) kinase cascade.

33 kinase (MAPKKK) of the stress-activated MAP kinase cascade.

34 ng-term downregulation of the ErbB2 tyrosine kinase cascade.

35 two of the kinase components in the JNK MAP kinase cascade.

36 r receptor induced mitogen activated protein kinase cascade.

37 itogen-activated protein kinase kinase (MEK) kinase cascade.

38 ynaptic role of a previously unknown p38 MAP kinase cascade.

39 Src-activated Raf-1 only stimulates the MAP kinase cascade.

40 ena, and the Mitogen Activated Protein (MAP) kinase cascade.

41 with the ability of Ras to activate the MAP kinase cascade.

42 TOR/S6K pathway and upregulation of the AMPK kinase cascade.

43 that a GPI-AP functions upstream of the MAP kinase cascade.

44 naling and the ERK mitogen-activated protein kinase cascade.

45 nstream of EPF ligands and upstream of a MAP kinase cascade.

46 olar membrane dynamics via a novel Yck3-Env7 kinase cascade.

47 e three-tiered Raf-MAPK/ERK kinase (MEK)-ERK kinase cascade.

48 ase, and hence the mitogen-activated-protein-kinase cascades.

49 tion of Msn independent of its impact on MAP kinase cascades.

50 ulates phosphorylation of JNK and ERK in MAP kinase cascades.

51 uch as ouabain, to regulate cellular protein kinase cascades.

52 plex and antagonizes ouabain-induced protein kinase cascades.

53 toward ERK activation and engages downstream kinase cascades.

54 s of transcription (Stat) factors or protein kinase cascades.

55 nits to upstream mitogen-activated protein 3-kinase cascades.

56 the roles of mitogen-activated protein (MAP) kinase cascades.

57 ined activation of the B-Raf/ERK and p38 MAP kinase cascades.

58 direct activation of intracellular tyrosine kinase cascades.

59 d through the activation of multiple protein kinase cascades.

60 ity, second messenger production and protein kinase cascades.

61 ultaneously remethylated DNA and reactivated kinase cascades.

62 lly from previously defined linear histidine kinase cascades.

63 in association with chromatin complexes and kinase cascades.

64 he cAMP/MAPK (cAMP/mitogen-activated protein kinase) cascade.

65 inase or ERK (extracellular signal-regulated kinase) cascade.

66 ERK and p38 mitogen-activated protein (MAP) kinases cascades.

67 two processes are orchestrated by the Hippo kinase cascade, a growth-suppressive pathway that ultima

68 oupling of 5-HT2 receptors to the ERK1/2/MAP Kinase cascade, a pathway not typically active in these

69 ules, and by stimulating eNOS as a result of kinase cascade activation by the high-affinity HDL recep

70 longevity of mitogen-activated protein (MAP) kinase cascade activation contribute to the nature of th

71 an element of the mitogen-activated protein kinase cascade, an intraneuronal signaling mechanism ass

72 Components of the pathway, which includes a kinase cascade and a downstream complex composed of YAP

73 Ctr1 involves the activation of the Ras-MAP kinase cascade and appears to be independent of its role

74 regulates Yki by promoting activation of the kinase cascade and by directly tethering Yki to the plas

75 echanism through which the conserved Pkh-Ypk kinase cascade and Cdc55-PP2A facilitate rapid, transien

76 g of the molecular actions of the core Hippo kinase cascade and discuss key open questions in the reg

77 BDNF-induced alterations in the ERK-MAP kinase cascade and in prefronto-accumbens glutamatergic

78 a novel role of PP2A in stimulating the MAP kinase cascade and indicate that the similar polyoma and

79 ing through a Byr2-mitogen-activated protein kinase cascade and one that signals through Scd1-Cdc42 t

80 he Raf/MEK/ERK/p90 ribosomal S6 kinase (RSK) kinase cascade and show how it determines adipogenic pot

81 te the Ras/MEK/ERK mitogen activated protein kinase cascade and to associate with epithelial tight-ju

82 f the Raf/MEK/extracellular signal-regulated kinase cascade and was correlated with the induction of

83 YODA (YDA) mitogen-associated protein (MAP) kinase cascade and WUSCHEL-LIKE HOMEOBOX (WOX) homeodoma

84 ations for signal transmission through other kinase cascades and might represent a general principle

85 gh the Akt and Ras-mitogen-activated protein kinase cascades and promote neuritogenesis and different

86 Kinase cascades and the modification of proteins by phos

87 actor on the activation status of downstream kinase cascades and transcription factors, cell survival

88 40 signaling required to activate downstream kinase cascades and transcription factors.

89 between the UV-induced JNK (c-Jun N-terminal kinase) cascade and corneal epithelial cell apoptosis an

90 the T cell receptor (TCR) proximal tyrosine kinase cascade, and facilitate distal signaling events i

91 ammed necrosis by initiating the pronecrotic kinase cascade, and that this is necessary for the infla

92 late Rho-dependent activation of the JNK MAP kinase cascade, and this requires endogenous CNK1.

93 eceptor Tyrosine Kinases, members of the MAP Kinase cascade, and WEE1.

94 inducible and stress-inducible genes, stress kinase cascades, and apoptosis.

95 P2Y receptors are coupled to protein kinase cascades, and signaling studies demonstrated that

96 decreased during development, the Pkn8-Pkn14 kinase cascade appears to negatively regulate mrpC expre

97 stablished, upstream regulators of the Hippo kinase cascade are less well defined, especially in mamm

98 Mitogen-activated protein kinase cascades are conserved in all eukaryotes.

99 Mitogen-activated protein (MAP) kinase cascades are crucial in the biosynthesis of proin

100 se and long-lasting activation of downstream kinase cascades are hallmarks of NGF signaling, yet our

101 Mitogen-activated protein kinase cascades are important signaling modules that con

102 MAP kinase cascades are inherently switch-like, but, during

103 Mitogen-activated protein kinase cascades are key players in plant immune signalin

104 The mitogen-activated protein (MAP) kinase cascades are key signal transduction pathways inv

105 We conclude LPS-induced kinase cascades are sufficient to alter cellular respons

106 -threonine phosphorelays, exemplified by MAP kinase cascades, are predominant in eukaryotes.

107 protein kinase and mitogen-activated protein kinase cascades, as well as prominent genes involved in

108 eal distinct consequences of inhibiting this kinase cascade at the level of ERK.

109 nce, and Hsp72 controlled the ERK-activating kinase cascade at the level of Raf-1.

110 YAP is inhibited by the Hippo pathway kinase cascade, at least in part via phosphorylation of

111 reveal that Paxillin is acting early in the kinase cascade, because it is required for accumulation

112 the PP2A AC dimer, does not activate the MAP kinase cascade, but does stimulate phosphorylation of AK

113 hrough phosphorylation by the Hpo/Warts core kinase cascade, but increasing evidence indicates that c

114 protein SAV1 promotes the activation of this kinase cascade, but the molecular mechanisms remain unkn

115 Activation of the MAP kinase cascade by both MTA and PyST has been demonstrate

116 scaffold protein that facilitates the Hippo kinase cascade by interacting with Sav1 and Lats1.

117 BP1, a scaffold protein inhibitor of protein kinase cascades, complexes with two 15LO isoforms, 15LO1

118 The core of the pathway is a kinase cascade composed of an upstream kinase Hpo (MST1/

119 sis thaliana mitogen-activated protein (MAP) kinase cascade composed of MEKK1, MKK1/MKK2, and MPK4 wa

120 The MAP kinase cascades, composed of a MAP3K, a MAP2K, and a MAP

121 the yeast Saccharomyces cerevisiae, the Snf1 kinase cascade comprises three Snf1-activating kinases,

122 ss-activated mitogen-activated protein (MAP) kinase cascade consisting of GhMAP3K15-Mitogen-activated

123 alpha) family of cytokines is dependent on a kinase cascade consisting of receptor-interacting kinase

124 Mammalian NKCCs are regulated by a kinase cascade consisting of the with-no-lysine (WNK) an

125 sting of an evolutionarily conserved protein kinase cascade, controls the DNA damage response in euka

126 A sequential kinase cascade culminating in activation of c-Jun N-term

127 are induced by activation of the Raf/MEK/ERK kinase cascade, culminating in upregulation of CDK1 with

128 pendent signal processing in interacting MAP kinase cascades demonstrating limited cross-talk.

129 DCs responded to STAg with low levels of MAP kinase cascade-dependent p38 activation, IL-12 productio

130 he Hippo pathway contains a highly conserved kinase cascade, different components have been identifie

131 Collectively, these data argue that the kinase cascades driving meiotic maturation potentiates I

132 The mitogen-activated protein kinase cascades elicit modification of chromatin protein

133 or kinases, and downstream mitogen-activated kinase cascades enforces proper stomatal patterning, and

134 The Mec1/Rad53/Dun1 DNA damage response kinase cascade exhibits multifaceted controls over RNR a

135 At the core of the Hippo pathway is a kinase cascade extending from the Hippo (Hpo) tumor supp

136 les of three major mitogen-activated protein kinase cascades, extracellular-signal-regulated kinase (

137 ast, inhibitors of mitogen-activated protein kinase cascades failed to prevent apoptosis.

138 s to the synapse through a calcium-dependent kinase cascade following activation of NMDA receptors.

139 lated kinase 5 (ERK5) are members of a three-kinase cascade for the activation of ERK5.

140 n and indicate virulent organisms usurp host kinase cascades for efficient intracellular growth.

141 Given the necessity of multiple persistent kinase cascades for ITM, we investigated whether protein

142 ugh PKA-dependent uncoupling of selected MAP kinase cascades from activating signals.

143 /extracellular signal-regulated kinase (ERK) kinase cascade has been proposed to both promote and inh

144 hat the structurally conserved Pbs2-Hog1 MAP kinase cascade has been specifically recruited as a glob

145 kinase (ERK)/MAPK (mitogen-activated protein kinase) cascade has been established as a potent regulat

146 A key regulator of many kinase cascades, heterotrimeric protein serine/threonine

147 ive forms of the upstream kinases in the MAP kinase cascades, i.e., MAPK kinase-3 (MKK3), MKK6 (the i

148 r the subnetwork signature included "protein kinase cascade," "IkappaB kinase/NFkappaB cascade," and

149 inases provide an expanded view of the Hippo kinase cascade in development and physiology.

150 dence of Rap1-mediated activation of the MAP kinase cascade in eukaryotic organisms.

151 ctivate the ERK1/2 mitogen-activated protein kinase cascade in HEK293 cells.

152 mechanism appearing to lie downstream of the kinase cascade in mammalian fibroblasts.

153 ngs demonstrate a new role for the Slt2p MAP kinase cascade in protecting the cell from programmed ce

154 Thus, we describe a novel kinase cascade in sensory neurons that enables the extra

155 with no stomata; the results implicate a MAP kinase cascade in stomatal development.

156 r other aberrations are occurring in the MAP kinase cascade in the melanoma types with infrequent mut

157 um channels and antagonizes a calcium-to-MAP kinase cascade in the neuron that becomes AWC(ON).

158 This underscores the importance of this kinase cascade in the progression of ischemic neuronal d

159 Here we show that IFN-gamma activates a kinase cascade in which death-associated protein kinase-

160 be a strategy to target overactive oncogenic kinase cascades in cancer.

161 st cancer cells via macrophage activation of kinase cascades in the cancer cells causing transcriptio

162 nd the DLK-1 MAPK (mitogen-activated protein kinase) cascade in regeneration.

163 The Hippo kinase cascade, in turn, is regulated by apical membrane

164 Kinase cascades, in which enzymes are sequentially activ

165 tes Ras-mediated stimulation of a downstream kinase cascade including the Raf-1 and ERK pathways lead

166 ts and that this effect is mediated by a MAP kinase cascade, including ASK1 and c-Jun N-terminal kina

167 s-mediated stimulation of downstream protein kinase cascades, including the Ras/Raf-1/MAPK/ERK kinase

168 either MPF or the mitogen-activated protein kinase cascade independently, functionally sensitizes IP

169 The Hippo pathway, a conserved kinase cascade, inhibits cardiomyocyte proliferation in

170 Stress-activated mitogen-activated protein kinase cascades instigate a range of changes to enable e

171 These studies suggest that the core Hippo kinase cascade integrates multiple upstream inputs, enab

172 WNK4 and SPAK/OSR1 to switch the classic two kinase cascade into a signal kinase transduction mechani

173 key eukaryotic signaling pathways is the MAP kinase cascade involved in vital cellular processes such

174 ts ability to simultaneously inhibit several kinase cascades involved in metastasis of cancer cells,

175 At the hub of this new pathway is a kinase cascade involving calcium/calmodulin-dependent pr

176 F1 form a holoenzyme and that a multiprotein kinase cascade involving G protein-coupled receptor kina

177 insulin signaling by activation of a serine kinase cascade involving PKCtheta in skeletal muscle.

178 phosphorylation (gammaH2AX) by an unrevealed kinase cascade involving polo-like kinase 3 (Plk3) in hu

179 The mitogen-activated protein kinase cascade is a conserved signal transduction pathwa

180 on of Yap-dependent proliferation, the Hippo kinase cascade is a critical regulator of organ growth.

181 network, the mitogen-activated protein (MAP) kinase cascade is a highly conserved signal transduction

182 The Raf-MEK-ERK protein kinase cascade is a highly conserved signaling pathway t

183 The Ras-Raf-mitogen-activated protein kinase cascade is a key growth-signaling pathway, which

184 ion, but the detailed mechanism of how a MAP kinase cascade is activated by TGF-beta receptors is not

185 The Hippo kinase cascade is an important regulator of organ growth

186 The MST-LATS kinase cascade is central to the Hippo pathway that cont

187 The Mst-Lats kinase cascade is central to the Hippo tumor-suppressive

188 Thus, the Snf1/AMPK kinase cascade is functionally conserved between yeast a

189 The ERK/MAP kinase cascade is important for long-term memory formati

190 the epidermal growth factor receptor-Src-Arg kinase cascade is known to be a critical trigger for inv

191 Drosophila and mammals, the canonical Hippo kinase cascade is mediated by Hpo/Mst acting through the

192 at after axon injury, activation of this MAP kinase cascade is required to switch the mature neuron f

193 the classic mitogen-activated protein (MAP) kinase cascade is the physiologic means of p38alpha acti

194 A major target of this kinase cascade is YAP1, a transcriptional coactivator th

195 Signal transduction via NFkappaB and MAP kinase cascades is a universal response initiated upon p

196 L, an upstream component of the C3G-Rap1-MAP kinase cascade, is SH3-dependent.

197 activation of c-Jun N-terminal kinase (JNK) kinase cascades, it is not known whether they utilize di

198 While a core kinase cascade leading from the protein kinase Hippo (Hp

199 Central to this pathway is a kinase cascade leading from the tumor suppressor Hippo (

200 APK signalling pathway is a highly conserved kinase cascade linking transmembrane receptors to downst

201 well as inhibitors of the mitogen-activated kinase cascade (MAPK) and cPLA2alpha, was used to examin

202 The Slt2p MAP kinase cascade mediates cyclin C destruction in response

203 d by the calmodulin-dependent protein kinase kinase cascade, mediates heightened inflammation and vas

204 Our findings uncover a kinase cascade mediating osmoregulation in higher plants

205 rane adenylyl cyclase cAMP-dependent protein kinase cascade modulated by PDE1C is critical in regulat

206 f the Hippo pathway in mammals consists of a kinase cascade, MST1/2 and LATS1/2, as well as downstrea

207 The Pkn8-Pkn14 protein kinase cascade negatively regulates mrpC expression.

208 re components of the Hippo pathway include a kinase cascade of MST1/2 and LATS1/2 and the transcripti

209 ciated protein (YAP) by the highly conserved kinase cascade of the Hippo signaling pathway has been i

210 The kinase cascade of the septation initiation network (SIN)

211 ive receptors, and mitogen-activated protein kinase cascades, orient asymmetric cell divisions and pr

212 hyperactivation of a third branch of the MAP kinase cascade, p38alpha signaling.

213 l density in cell culture, the Hippo pathway kinase cascade phosphorylates and inhibits the Yes-assoc

214 le contributions of a phosphatidylinositol-3 kinase cascade [PI3K, Akt, glycogen synthase kinase-3bet

215 eting components of the p38 stress-activated kinase cascade prevented the cell size increase elicited

216 Pharmacologic inhibition of the multi-kinase cascade prevents the Nef-dependent block in MHC-I

217 macological manipulations of this downstream kinase cascade produced a crowded branching defect in th

218 Input at the beginning of the kinase cascade produced a sharp, threshold-like response

219 results of this study indicate that the MAP kinase cascades prominently regulate IP10 gene expressio

220 h triggers a rapid activation cAMP-dependent kinase cascade (protein kinase A (PKA)).

221 Alternatively, SR-activated kinase cascades provide additional avenues for SR-regula

222 In this kinase cascade Raf activation ultimately results in extr

223 transcriptional machinery via intracellular kinase cascades rapidly activates primary immune respons

224 tified a previously unappreciated downstream kinase cascade regulated by Cdk5.

225 ntial action of IDA, HAE and HSL2, and a MAP kinase cascade regulates the programmed separation of ce

226 ed canonical signaling with the noncanonical kinase cascades regulates glomerular hypertrophy and mat

227 that MST11, MST7, and PMK1 function as a MAP kinase cascade regulating infection-related morphogenesi

228 Although mitogen-activated protein kinase cascade remains similar in both cells, Akt is mor

229 The Hippo kinase cascade represses the growth-promoting transcript

230 compound that interferes with the downstream kinase cascade rescued the mutant phenotype.

231 sequence of stimulus-specific shaping of the kinase cascade response.

232 ells significantly altered NGF-dependent MAP kinase cascade responses, inhibiting both p38 and ERK ki

233 The Hippo (Hpo) kinase cascade restricts tissue growth by inactivating t

234 The activation of this kinase cascade resulted in recruitment of extracellular

235 hrough the ERK and the phophatidylinositol-3-kinase cascades, resulting in activation of the transcri

236 osphoinositide 3-kinase (PI3K)/AKT/GSK-3beta kinase cascades, resulting in phosphorylation and stabil

237 uires plasma membrane recruitment of the MAP kinase cascade scaffold protein, Ste5.

238 stream pathways, including receptor tyrosine kinase cascades-signal through multiple effectors, such

239 ctivation of mitogen-activated protein (MAP) kinase cascade signaling by yeast mating pheromones invo

240 etics play a crucial role in determining MAP kinase cascade signaling dynamics and cell fate decision

241 athway stimuli both initiate and amplify MAP kinase cascade signaling.

242 d differentiation is dependent upon both MAP kinase cascades, since MEK inhibition blocked Rit-induce

243 eckpoint signals are transduced by a protein kinase cascade that also requires non-kinase mediator pr

244 nents of the mitogen-activated protein (MAP) kinase cascade that controls mating-pheromone-mediated s

245 f the Receptor Tyrosine kinase (RTK)/Ras/MAP kinase cascade that controls VPC cell fate, disrupts the

246 po pathway restrains proliferation through a kinase cascade that culminates in the inhibition of the

247 s whereby ApoE activates a non-canonical MAP kinase cascade that enhances APP transcription and amylo

248 Hippo is a kinase cascade that functions to phosphorylate and inact

249 se, which cooperates with Cdk5 to initiate a kinase cascade that governs cytoskeletal rearrangements

250 athway controls tissue growth through a core kinase cascade that impinges on the transcription of gro

251 e cluster and CrMYC2 act downstream of a MAP kinase cascade that includes a previously uncharacterize

252 ach employ a mitogen-activated protein (MAP) kinase cascade that includes Ste20, Ste11, and Ste7.

253 an ancient organ size control pathway, is a kinase cascade that inhibits developing cardiomyocyte pr

254 al cells through a mitogen-activated protein kinase cascade that involves PI3K, Cdc42, p21-activated

255 the activation of an intracellular tyrosine kinase cascade that involves the sequential activation o

256 MPK) is a fundamental component of a protein kinase cascade that is an energy sensor.

257 Hippo pathway is an evolutionarily conserved kinase cascade that is fundamental for tissue developmen

258 HAESA-like 2 (HAE/HSL2) that regulate a MAP kinase cascade that is required for abscission.

259 cumulation, which in turn activates a serine kinase cascade that leads to defects in insulin signalin

260 The results suggest that PKG initiates a kinase cascade that leads to phosphorylation of SERT by

261 suppresses metastasis by triggering a Hippo kinase cascade that leads to phosphorylation, cytoplasmi

262 ll growth and regulates organ size through a kinase cascade that leads to the phosphorylation and nuc

263 It is a kinase cascade that negatively regulates the activity of

264 response (DDR) is brought about by a protein kinase cascade that orchestrates DNA repair through tran

265 Our study identified a complete MAP kinase cascade that phosphorylates and activates a key W

266 The Hippo pathway, a kinase cascade that prevents adult cardiomyocyte prolife

267 pheromone, which is mediated by a conserved kinase cascade that transduces the signal from the phero

268 ork (SIN) is an Spg1-GTPase-mediated protein kinase cascade that triggers actomyosin ring constrictio

269 he pathway consists of a MST and LATS family kinase cascade that ultimately phosphorylates and inacti

270 veral negative growth regulators acting in a kinase cascade that ultimately phosphorylates and inacti

271 e membrane, the receptors signal to activate kinase cascades that are essential for the modulation of

272 ells, initiating signal transduction through kinase cascades that contribute to steroid hormone actio

273 stimuli through activation of intracellular kinase cascades that regulate tissue plasticity.

274 In addition, understanding of the three MAP kinase cascades, the mTOR-p70S6 kinase pathway, and the

275 l that Nck integrates nephrin with the Hippo kinase cascade through association with the adaptor prot

276 n N-terminal kinase/stress-activated protein kinase) cascade through inhibition of MEK4/7.

277 hes that initiate signalling through the MAP kinase cascade to control cellular proliferation, differ

278 rough an evolutionarily conserved Src family kinase cascade to drive cytoskeletal rearrangements and

279 we show that UVB activates the p38 MAPK/MSK1 kinase cascade to phosphorylate histone H3 at Ser10 and

280 itical nodes that relay signals from protein kinase cascades to the actin cytoskeleton, in particular

281 The core of the Hippo pathway consists of a kinase cascade, transcription coactivators, and DNA-bind

282 ins largely undefined how DNA damage-induced kinase cascades trigger the timely destruction of Set8 t

283 within a network of interacting feed-forward kinase cascades typified by the MAP kinase cascade.

284 The mitotic exit network (MEN), a protein kinase cascade under the switch-like control of the smal

285 tion of the ERK1/2 mitogen-activated protein kinase cascade via a mechanism that requires kallikrein

286 hat this protein complex regulates the Hippo kinase cascade via direct binding to Hpo and Sav.

287 Although the ATR-Chk1 kinase cascade was associated with hypoxia-induced p53 a

288 We found that signaling through the MEN kinase cascade was mediated by an unusual two-step proce

289 hese assay conditions, activation of the MAP kinase cascade was not sufficient to induce NIH3T3 cell

290 ng proteins in the mitogen-activated protein kinase cascade were up-regulated along with human epider

291 Central to this pathway is a kinase cascade wherein Hippo (Hpo), in complex with Salv

292 smit DNA damage signals through the ATR-Chk1 kinase cascade, whether post-translational modifications

293 essential spindle pole body (SPB)-associated kinase cascade, which controls the formation, maintenanc

294 onse to Tem1's activity at the dSPB, the MEN kinase cascade, which functions downstream of Tem1, accu

295 The core of the Hpo pathway is a kinase cascade, which in Drosophila involves the Hpo and

296 etween Akt and the mitogen-activated protein kinase cascade, which is also frequently associated with

297 ontrolled by the Pkn8/Pkn14 serine/threonine kinase cascade, which phosphorylates MrpC on threonine r

298 egron responds rapidly to a signal-activated kinase cascade, which regulates SfIAP levels and thus ap

299 he prospect of targeting multifold oncogenic kinase cascades, which jointly contribute to multiresist

300 molecular patterns (PAMPs) and activate MAP kinase cascades, which regulate changes in gene expressi