1 ch each behavioral stage and to become fully
kindled (
8.63 +/- 0.92 vs. 16.17 +/- 1.37; Mean +/- S.E.
2 , a separate group of animals (Expt. 3) were
kindled accordingly and processed for c-Fos and basic fi
3 hrough cannulae in the LC ipsilateral to the
kindled amygdala in 6 kittens.
4 ae adjacent to stimulating electrodes in the
kindled amygdala, and evoked seizures were tested 10-12
5 and synaptic plasticity in naive and in MDA-
kindled anaesthetised rats.
6 ing patterns during AGS were compared in non-
kindled and AGS kindled GEPR-9s.
7 us burst frequency between slices taken from
kindled and control animals.
8 portions of sprouted mossy fiber synapses in
kindled and kainic acid-treated rats.
9 pocampal activity was identified in both non-
kindled and kindled seizures, revealing a novel mechanis
10 During AGS in both AGS
kindled and non-kindled GEPR-9s, vlPAG neurons displayed
11 ce, but rescued LTP in slices taken from the
kindled animal.
12 as significantly longer in slices taken from
kindled animals as compared to those taken from implante
13 ng effects on spontaneous epileptogenesis in
kindled animals as well.
14 but not of p38, is significantly enhanced in
kindled animals compared with their naive counterparts i
15 indling as well as phenobarbital-treated non-
kindled animals recovered within 2 months after the lesi
16 Individual seizures in
kindled animals showed more significant increases in bra
17 f the JNK substrate paxillin was enhanced in
kindled animals, but not that of c-Jun.
18 f the generalised seizure threshold in fully
kindled animals.
19 f late paired-pulse depression recorded from
kindled animals.
20 shows for the first time that in control and
kindled basolateral amygdala neurons, two pharmacologica
21 Indeed, the hope
kindled by the germ theory of disease was rapidly subdue
22 However, the 'inflammatory fire'
kindled by the host response must be tightly controlled
23 Nanographenes have
kindled considerable interest in the fields of materials
24 leptic effects of 2DG were evaluated in rats
kindled from olfactory bulb or perforant path.
25 r was induced by AP7 (1 and 7.5 nmol) in AGS-
kindled GEPR-3s.
26 However, in AGS-
kindled GEPR-9s these responses showed a precipitous fir
27 isorders, on the CeA to vlPAG pathway in AGS-
kindled GEPR-9s was also evaluated.
28 ortant for its anticonvulsant effects in AGS-
kindled GEPR-9s, and this effect may contribute to gabap
29 During AGS in both AGS kindled and non-
kindled GEPR-9s, vlPAG neurons displayed tonic firing du
30 led levels and reversibly blocked PTC in AGS-
kindled GEPR-9s.
31 asing stimulus intensity, as compared to non-
kindled GEPR-9s.
32 lPAG neuronal firing change was seen only in
kindled GEPR-9s.
33 ing AGS were compared in non-kindled and AGS
kindled GEPR-9s.
34 etanus-induced afterdischarges that could be
kindled in the absence of NMDA receptor activation.
35 The data suggest that
kindled-
induced hyperexcitability of the amygdala and li
36 arity complex in Drosophila and vertebrates,
kindled intense interest in polarity pathways.
37 The findings suggest a 'critical period' in
kindled kittens for onset of spontaneous temporal lobe e
38 ontaneous seizure susceptibility in amygdala-
kindled kittens.
39 onal responses to CeA stimulation to pre-AGS-
kindled levels and reversibly blocked PTC in AGS-kindled
40 ehavior and short-term memory in control and
kindled male mice during tonic stimulation of dopaminerg
41 l CA1 regions, and again in both control and
kindled male mice.
42 exploration and short-term spatial memory in
kindled mice, essentially rescuing the seizure-induced c
43 e has a dual effect on LTP in control versus
kindled mice, such that application of dopamine prevente
44 eorge Schwert in the biochemistry department
kindled my interest in biochemistry.
45 h EC50 values of 36 nM (control) and 1.2 nM (
kindled neurons).
46 EC50 values of 297 nM (control) and 10.8 nM (
kindled neurons).
47 Moreover, in
kindled neurons, agonists at either group II- or group I
48 The rats were
kindled once daily using afterdischarge-threshold electr
49 8 and each day thereafter until either fully
kindled or until day 20, the animals received daily trea
50 ivation was comparable between human TLE and
kindled rat granule cells.
51 tor 6 Hz (32 mA) (mice, ip), and hippocampal
kindled (
rat, ip) seizure tests providing excellent prot
52 Hippocampus-
kindled rats also displayed fear-potentiated startle, bu
53 urons using a small microelectrode array and
kindled rats by a rapid, recurrent hippocampal stimulati
54 voltage-clamp methods in granule cells from
kindled rats experiencing spontaneous seizures demonstra
55 ceptor agonist, DCG-IV, were tested in fully
kindled rats following daily electrical stimulation of t
56 Amygdala-
kindled rats had exaggerated fear-potentiated startle co
57 tion in the number of GAD67-cells in caudate-
kindled rats in the dentate gyrus and CA3 hippocampal su
58 Using hippocampal-
kindled rats to ensure maximal clinical expression, we d
59 ir cells in the dentate gyrus of hippocampal-
kindled rats, which suggests a possible reduction of syn
60 n in GABA synaptic activity in both sham and
kindled rats, while no effect of either DO34 or of the C
61 itude of spontaneous IPSCs in either sham or
kindled rats.
62 ed startle, but no greater than that of sham-
kindled rats.
63 ed fear-potentiated startle compared to sham-
kindled rats.
64 on at high stimulus intensities in naive and
kindled rats.
65 naptic depression, over GABA transmission in
kindled rats.
66 In brain slices obtained from epileptic (
kindled)
rats, the excitatory drive onto inhibitory inte
67 ched the values previously reported for TLE (
kindled)
rats.
68 The study confirms previous findings in
kindled rodents to show that CLON and IDA can have oppos
69 ffectively laden touch in humans has further
kindled scientific interest in the area.
70 This report describes amygdala-
kindled seizure development and the post-kindling course
71 et time quantification provided evidence for
kindled seizure propagation from the ipsilateral to the
72 have contrasting effects on evoked amygdala-
kindled seizure susceptibility.
73 indled seizures exhibited full-scale 5 stage-
kindled seizures 24 h after DBS.
74 tic neural networks are involved in amygdala-
kindled seizures and that DBS, if well timed with the on
75 d caused a twofold slowing in progression of
kindled seizures at both stimulation sites.
76 Furthermore,
kindled seizures exacerbated later cognitive impairment,
77 y 1 of the 10 rats for which DBS had blocked
kindled seizures exhibited full-scale 5 stage-kindled se
78 Our DBS protocol completely blocked
kindled seizures in 10 out of 23 (43.5%) rats studied.
79 line-3-carboxylate, picrotoxin, and amygdala-
kindled seizures in mice (ED50 values, 84-97 mg/kg).
80 R127303 delays the acquisition and decreases
kindled seizures in mice, indicating that the drug slows
81 Kindled seizures markedly elevated CRF and CRF-BP in the
82 idization to examine the effects of amygdala-
kindled seizures on the mRNA levels of CRF and CRF-BP.
83 on of the mTOR inhibitor rapamycin following
kindled seizures rescued enhanced remote and long-term m
84 When stage 5-
kindled seizures were achieved by daily amygdala kindlin
85 inhibitor rapamycin, administered following
kindled seizures, for markers of E:I balance.
86 1 (0.25 mg/kg, i.p.), and the development of
kindled seizures, produced an increase in AD thresholds
87 ivity was identified in both non-kindled and
kindled seizures, revealing a novel mechanism of seizure
88 r synaptic plasticity are impaired following
kindled seizures.
89 ntia nigra pars reticulata (SNr) on amygdala-
kindled seizures.
90 networks that may prevent the recurrence of
kindled seizures.
91 ling and on fully developed stage 5 amygdala
kindled seizures.
92 ces from control rats and rats with amygdala-
kindled seizures.
93 mals is altered following the development of
kindled seizures.
94 nd are enhanced following the development of
kindled seizures.
95 nd facilitated SE onset but had no effect on
kindled seizures.
96 AS model mice
kindled similarly to wild-type mice, but they displayed
97 In the dark recovery phase, the
kindled state relaxes thermally on a time scale of secon
98 te to the enduring changes that underlie the
kindled state.
99 er at different time points to check for the
kindled state.
100 The "
kindled"
state, wherein depressive episodes occur with l
101 Beginning 48 h after surgery, animals were
kindled to evoke Stage 0 or Stage 1 seizure activity dur
102 Rats were
kindled to stage 5 by afterdischarge-threshold electrost
103 h stage V seizures and to become permanently
kindled was significantly greater in TRH-NP-treated subj
104 has enhanced anticonvulsant effects in fully
kindled wild-type mice, but not delta-subunit knock-out