ライフサイエンスコーパス: kinetic analysis

1 cular interactions, making them suitable for kinetic analysis.

2 y extent, and can provide valuable real-time kinetic analysis.

3 -resolved absorption spectroscopy and global kinetic analysis.

4 t were measured using a 2-tissue compartment kinetic analysis.

5 ion was overturned on the basis of extensive kinetic analysis.

6 ry excretion during a 24-h period and from a kinetic analysis.

7 erase and butyrylcholinesterase using enzyme kinetic analysis.

8 sembly process as constraints for subsequent kinetic analysis.

9 etamide are rationalized by detailed in situ kinetic analysis.

10 dynamics simulation, electrophysiology, and kinetic analysis.

11 lecular dynamic simulations (BOMD) and micro-kinetic analysis.

12 mproved precatalyst (thtAuBr3) to facilitate kinetic analysis.

13 one species to another, as measured through kinetic analysis.

14 rived using an arterial input function-based kinetic analysis.

15 bition of the studied isozymes by a thorough kinetic analysis.

16 g, isotopic labeling experiments ((2)H), and kinetic analysis.

17 ve induced-fit, challenging computational or kinetic analysis.

18 preference for iodination, as illustrated by kinetic analysis.

19 nzymatic reactions and Michaelis-Menten-type kinetic analysis.

20 haracterization of an iron-metallacycle, and kinetic analysis, allowed the sound elucidation of a pla

21 Rapid kinetics analysis also shows that ring resetting of a se

22 Kinetic analysis and computer simulations were performed

23 Preliminary kinetic analysis and density functional calculations sup

24 A combination of kinetic analysis and DFT calculations reveals the comple

25 Kinetic analysis and DFT calculations suggest that the C

26 Pre-steady-state kinetic analysis and elucidation of the crystal structur

27 echanism-based inhibitors that allow precise kinetic analysis and faithfully mimic the transition sta

28 To simplify kinetic analysis and handling, a variant PCM-F was gener

29 Reaction progress kinetic analysis and isotopic labeling studies corrobora

30 Mechanistic investigation through kinetic analysis and isotopic labeling studies indicates

31 N bond formation was probed via initial rate kinetic analysis and kinetic isotope effect experiments

32 Kinetic analysis and laboratory methods were developed t

33 Kinetic analysis and modeling reveal that the behavior o

34 arious formats of assays for equilibrium and kinetic analysis and rapid determination of degradation

35 Kinetic analysis and reaction profile fitting of both th

36 Transient kinetic analysis and stopped-flow FRET demonstrated that

37 Kinetic analysis and structural studies disclosed that I

38 , along with the results of the steady-state kinetic analysis and the absorption spectroscopy titrati

39 plications on the selectivity, activity, and kinetic analysis, and any attempt to draw structure-acti

40 hiometric reactions, NMR monitoring studies, kinetic analysis, and DFT calculations, a mechanism invo

41 f the reactor and the benefits of performing kinetic analysis as a routine part of reaction optimizat

42 By using reaction progress kinetic analysis as an evaluation method for the obtaine

43 near the ZnO surface, allowing steady-state kinetic analysis as in other hydrodynamic methods.

44 d enzymes were characterized by steady-state kinetic analysis at temperatures from 0 to 25 degrees C

45 8alpha and allowed discovery of a predictive kinetic analysis based on cooperativity to distinguish T

46 Kinetic analysis based on time-resolved fluorescence rev

47 cessfully demonstrate binding specificity in kinetic analysis biomechanics in peptide aptamers and GO

48 inhibitors that we have subjected to further kinetic analysis by comparing k(off) constants determine

49 ve tissue are not amenable to structural and kinetic analysis by conventional methods.

50 of multiple assembly pathways, and show how kinetic analysis can be used to distinguish different as

51 f Ki, Kd, IC50, and/or EC50, a more thorough kinetic analysis can provide useful information for the

52 This dynamic process can be studied by kinetic analysis, combined with the use of specific inhi

53 Kinetic analysis confirmed the existence of an intermedi

54 mentary biophysical, structure-function, and kinetic analysis define the features that facilitate the

55 Binding and kinetic analysis demonstrate that the MUG-K68N substitut

56 Further kinetic analysis demonstrated first-order kinetics with

57 Preliminary kinetic analysis demonstrated that BPND values obtained

58 Our kinetic analysis demonstrated that the rate of key enzym

59 Single-molecule kinetic analysis demonstrates that the IUTD enters from

60 This massively parallel enzyme kinetics analysis detailed the specificity of ADAMTS13 a

61 ks and guides users through the key steps of kinetic analysis: determination of constraints to be pla

62 Using a combination of kinetic analysis, deuterium labeling, and reactivity stu

63 Surface plasmon resonance-based kinetic analysis enabled the selection of mini-Abs with

64 The kinetic analysis exhibited discontinuities in the Arrhen

65 Molecular modeling studies in tandem with kinetic analysis exhibited that these hybrids target bot

66 spectroscopy/steady-state isotopic transient kinetic analysis) experiments demonstrates that the rate

67 Kinetic analysis for different E2 concentrations shows t

68 Kinetic analysis for different E2 concentrations shows t

69 A kinetic analysis for TVBN, SSP, hardness, adhesiveness a

70 PL titrations, thermochemical cycles, and kinetic analysis (for the mcb compounds) provided self-c

71 Kinetic analysis further indicated that PPTases possess

72 Kinetic analysis further shows that W32 oxidation likely

73 Kinetic analysis further shows the antioxidant reactivit

74 Chlorophyll fluorescence kinetic analysis has become an important tool in basic a

75 via a Makosza-like interfacial process, and kinetic analysis has shown that the reaction possesses a

76 In steady-state kinetic analysis, hpol eta preferred to incorporate dATP

77 Modeling and kinetic analysis identified Pz-1 as a type II tyrosine k

78 Kinetics analysis identifies that the slow solid-state s

79 Kinetic analysis implicated two ionizable groups in the

80 Observations from kinetic analysis in concert with in situ (19)F NMR monit

81 ce temperature and Z-value commonly used for kinetic analysis in food microbiology.

82 Kinetic analysis, in situ FTIR, and in situ XAS measurem

83 occupies the active site cavity of G9a, and kinetic analysis indicates competitive inhibition of G9a

84 Kinetic analysis indicates that, in LB medium supplement

85 LTA4 concentrations during the steady-state kinetics analysis, indicating poor lipid substrate bindi

86 of rWGS activity over 92 h and supported by kinetic analysis, infrared and X-ray absorption spectros

87 al evidence (spectroscopic characterization, kinetic analysis, intermolecular reactivity, and radical

88 Kinetic analysis, intrinsic fluorescence studies, and in

89 his noninvasive dual-window acquisition with kinetic analysis is recommended.

90 Kinetic analysis, labeling, competition, and nonlinear e

91 sion estimates is not affected by the tracer kinetic analysis method used.

92 ecently reported variable-time normalization kinetic analysis method was used to delineate the comple

93 pressure IR (HPIR) and the reaction progress kinetic analysis methodology suggested two steps in the

94 From kinetic analysis, new developed mechanistic scheme which

95 Kinetic analysis of (11)C-GSK215083 uptake in the human

96 dy are validated with biochemical assays and kinetic analysis of a panel of HDX-MS guided variant enz

97 study, we present the first biochemical and kinetic analysis of a peptidoglycan O-acetyltransferase

98 Herein we report the first steady-state kinetic analysis of a PKS DH domain employing LC-MS/MS a

99 Here, we identify and provide a detailed kinetic analysis of a transcription cycle analogous to a

100 Application to kinetic analysis of a wide variety of transformations (a

101 Furthermore, kinetic analysis of active site alanine mutants indicate

102 Separately, kinetic analysis of alanine variants has demonstrated th

103 d absence of ligands, followed by a detailed kinetic analysis of Bet v 1 processing by individual end

104 We employed kinetic analysis of binding and activation of human PLG

105 Here, we used kinetic analysis of binding with multiple concentrations

106 A detailed kinetic analysis of cardiac myosin has shown that the dr

107 Kinetic analysis of channel gating revealed that AITC ac

108 pattern was confirmed through synthesis and kinetic analysis of cleavage of a set of optimized pepti

109 Intriguingly, cell kinetic analysis of clonal isolates derived from single

110 Here, the authors show an operando kinetic analysis of CO2 hydrogenation over a palladium c

111 Reaction progress kinetic analysis of data obtained through in situ FTIR s

112 Kinetic analysis of DNA cleavage suggests flexible tethe

113 Synchronized cleavage improved kinetic analysis of DNA repair, revealing that cells res

114 This detailed kinetic analysis of Drosophila myosin carrying the R759E

115 Conclusion: Kinetic analysis of dynamic (18)F-Gln-PET images demonst

116 key findings from the first pre-steady state kinetic analysis of each site.

117 Kinetic analysis of extraction was performed.

118 Here we report the steady state kinetic analysis of field-effect-controlled outer-sphere

119 Kinetic analysis of five different AD-causing mutations

120 Here we report a kinetic analysis of fluorescent guanine nucleotides bind

121 In contrast, the kinetic analysis of GDP-ManPP was only possible with thr

122 Kinetic analysis of GoxA revealed allosteric cooperativi

123 on Pt in the aqueous phase was determined by kinetic analysis of H(2) reacting with D(2) O to HDO, HD

124 escence assay, we present the first in-depth kinetic analysis of initial transcription and promoter e

125 sing these techniques, we describe the first kinetic analysis of LD growth and secretion at peak lact

126 The assay allowed kinetic analysis of ligand-receptor binding in living HE

127 Most interestingly, results of kinetic analysis of LPS bioactivity, using modified limu

128 Kinetic analysis of microcluster assembly reveal surpris

129 Kinetic analysis of miniature EPSCs revealed quantal rel

130 A detailed steady-state kinetic analysis of MtNadD suggests that ATP must first

131 s likely to be bendable in one direction and kinetic analysis of mutant DNA sequences with biolayer i

132 e subject of controversy; we report that the kinetic analysis of ndSQR is consistent with glutathione

133 Kinetic analysis of NF-kappaB levels following loss of s

134 Kinetic analysis of NiCl(CCl2CCl3)(CNAr(Mes2))2 decompos

135 Here we report a detailed kinetic analysis of nucleotide incorporation and exonucl

136 cted out of eight food-grade enzymes for the kinetic analysis of peanut protein hydrolysis that lead

137 Kinetic analysis of peptide substrate phosphorylation an

138 Kinetic analysis of percentage and yield of preplasma an

139 -dependent Stokes and anti-Stokes SERS, with kinetic analysis of photocatalytic reactions in an Ag na

140 ar approach can be potentially developed for kinetic analysis of protein-small molecule binding by ot

141 We describe a novel method of kinetic analysis of radioligand binding to neuroreceptor

142 Both treatments facilitate kinetic analysis of reactions suffering catalyst activat

143 These processes complicate the kinetic analysis of reactions, often directing researche

144 Transcript analysis coupled with kinetic analysis of recombinant enzymes in Escherichia c

145 yclic carbene (NHC) was quantified through a kinetic analysis of reductively triggered chloride disso

146 Steady-state kinetic analysis of reverse transcription and RNA primer

147 Kinetic analysis of ribozymes with systematically altere

148 Here we develop Single Molecule Kinetic Analysis of RNA Transient Structure (SiM-KARTS)

149 We first examined the roles of Mg(2+) by kinetic analysis of single nucleotide incorporation cata

150 Kinetic analysis of single-channel recordings made with

151 The x-ray structures and kinetic analysis of site-directed mutants are consistent

152 Kinetic analysis of specific peptide generation reveals

153 Comparative kinetic analysis of stand-alone KR1 as well as a truncat

154 We report a pre-steady-state kinetic analysis of structural rearrangements of the DNA

155 Kinetic analysis of sugar translocation obtained from si

156 Kinetic analysis of the activation reaction according to

157 presents a detailed computational study and kinetic analysis of the aminolysis of dithioates, dithio

158 presents a detailed computational study and kinetic analysis of the aza-Michael addition of primary

159 This report describes the first detailed kinetic analysis of the Banert cascade proceeding by bot

160 Here, by means of a systematic kinetic analysis of the Bi-Te system reacting to Bi2Te3,

161 We have performed a kinetic analysis of the blocking mechanism of the protot

162 We undertook a detailed kinetic analysis of the drug responses of K13 wild-type

163 Critically, pre-steady-state kinetic analysis of the E3 rRNase(IDP)-Im3 complex demon

164 Further kinetic analysis of the ECEC path revealed that base inc

165 er indirect flight muscle S1, we performed a kinetic analysis of the effect of mutations in the conve

166 Kinetic analysis of the electrochemical response with ti

167 Kinetic analysis of the encapsulation-isomerization even

168 Kinetic analysis of the enzymatic activities toward 3-ox

169 Third, binding and kinetic analysis of the FMN-binding site mutants of thes

170 performed a comprehensive thermodynamic and kinetic analysis of the folding mechanism of mSOD1 in th

171 tions with a comprehensive thermodynamic and kinetic analysis of the growth process, which explains t

172 Kinetic analysis of the HIV-1 Tat (transactivator of tra

173 The kinetic analysis of the ligations using model peptides s

174 e report here the first detailed biochemical kinetic analysis of the motor domain of the human beta-c

175 Steady-state kinetic analysis of the new mechanism is consistent with

176 Furthermore, the kinetic analysis of the opening/closing transition revea

177 By X-ray absorption spectroscopy and kinetic analysis of the oxygen evolution reaction, we sh

178 Kinetic analysis of the pancreas was performed using a 1

179 We present here the first complete in situ kinetic analysis of the PD-1/PD-ligands/B7-1 system.

180 Kinetic analysis of the photoelectrochemical processes i

181 Kinetic analysis of the reaction between the respective

182 Kinetic analysis of the reaction in the presence of the

183 Kinetic analysis of the reaction is presented showing a

184 s in continuous assays, and pre-steady-state kinetic analysis of the target enzymes.

185 A transient kinetic analysis of the ternary complex formation aided

186 Moreover, steady-state kinetic analysis of the TLS process indicated that deoxy

187 Stoichiometric isotopic experiments and the kinetic analysis of the transformations demonstrate that

188 To date, kinetic analysis of this complex process has been achiev

189 ion by Trm10, we performed a biochemical and kinetic analysis of Trm10 and variants with alterations

190 The assay was used to conduct a comparative kinetic analysis of two LanM enzymes (HalM2 and ProcM) t

191 Kinetic analysis of V(NO) for the B5/B5R/Cygb system wit

192 del system through detailed Michaelis-Menten kinetic analysis of various substrates and inhibitors.

193 ction of the ionic liquid concentration, the kinetic analysis of which coupled with density functiona

194 Furthermore, stopped-flow kinetic analysis of Zika NS5-, RdRp- and MTase-SLA inter

195 It is shown from kinetics analysis of both the enzyme catalytic responses

196 Here we demonstrate a quantitative binding kinetics analysis of drug-target interactions to investi

197 fied conserved transitions between them, and kinetic analysis paralleled these observations.

198 Kinetic experiments using reaction progress kinetic analysis protocols demonstrate that inhibition o

199 an excellent correlation with K(i) from full kinetic analysis (R (2) = 0.97).

200 to parameters derived from full quantitative kinetic analysis (R(2) < 0.34).

201 es obtained from tail currents together with kinetics analysis reveal that the fast and slow gates of

202 (IM-MS) analytical platform and in-solution kinetics analysis reveal the comprehensive structural an

203 Kinetic analysis revealed a larger turnover number for r

204 Biochemical and kinetic analysis revealed Lys(147) to be an intramolecul

205 Kinetic analysis revealed position 596 also plays a role

206 nalysis using Logan plots and full nonlinear kinetic analysis revealed significant inhibition for bot

207 Kinetic analysis revealed that allosteric and orthosteri

208 Enzyme kinetic analysis revealed that BA inhibited tyrosinase a

209 Kinetic analysis revealed that hOCT1, hOCT2, hOCT3, hMAT

210 Kinetic analysis revealed that most target mutation occu

211 Rapid kinetic analysis revealed that reduction of the flavin c

212 Thus, our kinetic analysis revealed that terpenoids are efficaciou

213 In contrast, our kinetic analysis revealed the presence of abundant CD25(

214 Kinetic analysis revealed the rate-limiting step of inac

215 Enzyme kinetic analysis reveals a dynamic relationship between

216 Kinetic analysis reveals co-occupancy of the allosteric

217 Our steady-state kinetic analysis reveals that A3A discriminates against

218 Our kinetic analysis reveals that aggregation proceeds via m

219 Kinetic analysis reveals that perovskite films with less

220 Simple kinetic analysis reveals that photo-oxidation of PhPyr b

221 Importantly, the kinetic analysis reveals that the capacitance of SF-3D G

222 Quantitative kinetic analysis reveals that the CP-mDia1 antagonism th

223 Furthermore, multiple-turnover kinetic analysis reveals that the rate-determining step

224 Steady-state kinetic analysis reveals that WRN improves hpol kappa-ca

225 The force-dependent kinetics analysis reveals a mechanism that requires DNA

226 tunnel and LPA in the pocket, together with kinetic analysis, reveals that bile salts act as partial

227 euterium labeling studies, reaction progress kinetic analysis (RPKA) and computational studies corrob

228 -depth kinetic study using reaction progress kinetic analysis (RPKA) has been performed to probe the

229 EPR studies in tandem with kinetic analysis show that the 490 nm chromophore of 2 i

230 Kinetic analysis showed brain uptake to be relatively hi

231 Kinetic analysis showed that ARM1 and related analogues

232 al features of the substrate-binding pocket, kinetic analysis showed that AtFAAH efficiently uses bot

233 Kinetic analysis showed that Mg(2+) and Mn(2+) ions incr

234 Our prior kinetic analysis showed that nonnucleoside inhibitors bi

235 hat NaOt-Bu was necessary for catalysis, but kinetic analysis showed that the base is not involved in

236 Kinetic analysis showed that the compounds function as r

237 Kinetic analysis showed that XXT5 has a 7-fold higher Km

238 The kinetic analysis showed the absorption efficiency was hi

239 Kinetic analysis shows that all enzymes characterized ha

240 A Hammett kinetic analysis shows that catalytic turnover is promot

241 A steady-state kinetic analysis shows that interaction with SSB stimula

242 Our kinetic analysis shows that NNI2 do not significantly bl

243 Our growth kinetic analysis shows that the calcined materials have

244 A kinetic analysis shows that the HAT by chain-carrying HO

245 Kinetic analysis shows that the isotope exchange process

246 independently by 2 operators using in-house kinetic analysis software that applied a 1-tissue-compar

247 Steady-state isotopic transient kinetic analysis (SSITKA) (CO + H(2)(16)O -> CO + H(2)(1

248 Steady state isotopic transient kinetic analysis (SSITKA) of ammonia synthesis showed th

249 Results from kinetic analysis, stoichiometric reactions of isolated c

250 Kinetic analysis suggested a minor and variable contribu

251 Molecular kinetic analysis suggested that intravascular taste sens

252 Kinetic analysis suggests that binding of AM-8138 to the

253 The most successful binding kinetics analysis systems at this moment include surface

254 We use kinetic analysis, targeted experiments, and previous lit

255 AUC) provides a better correlation with full kinetic analysis than does standard SUV.

256 irected mutagenesis followed by steady state kinetic analysis to ascertain their catalytic functions

257 systems, by applying our stoichiometric and kinetic analysis to autocatalysis emerging from coupled

258 e key microscopic steps by applying a global kinetic analysis to both the decrease in the concentrati

259 L-nucleotides and performed pre-steady-state kinetic analysis to determine the D-stereoselectivity me

260 ition of highly reproducible data and global kinetic analysis to determine the mechanistic influence

261 We carried out pre-steady-state kinetic analysis to elucidate the kinetic mechanism of t

262 In this study, we use structural and kinetic analysis to investigate the mechanism of these i

263 e performed a detailed non-linear regression kinetic analysis to simultaneously fit families of subst

264 we therefore extend contemporary statistical kinetic analysis to study collective transport phenomena

265 An Interactive Continuous Enzyme Kinetics Analysis Tool (ICEKAT) was developed for semi-a

266 The combined use of reaction kinetic analysis, ultrafast spectroscopy, and stoichiome

267 Here we used a combination of fine kinetic analysis under specific conditions (pH, PN conce

268 Kinetic analysis underscored the importance of motif 1a

269 to evaluate (18)F-AV-1451 binding with full kinetic analysis using a metabolite-corrected arterial i

270 -site affinity label, together with detailed kinetic analysis using a variety of well defined oligosa

271 tal cortex and the cerebellum derived from a kinetic analysis using MA1.

272 isition times were tested comparatively to a kinetic analysis using MRTM2.

273 Here, we demonstrate by kinetic analysis using physically tethered DNA substrate

274 In vitro kinetic analysis using purified protein demonstrated tha

275 uptake (BPND), was measured in subjects with kinetic analysis using the arterial input function both

276 distribution volume (V(T)) was measured with kinetic analysis using the arterial input function in br

277 tal cortical subdivisions) was measured with kinetic analysis using the arterial input function.

278 n the regions of interest were measured with kinetic analysis using the arterial input function.

279 The inhibition was studied by kinetic analysis, UV-vis spectrum measurements, and X-ra

280 Ferricyanide reduction kinetic analysis (variation of ferricyanide absorption w

281 ion allowed easy scale up, while in-operando kinetic analysis was accomplished by online flow-NMR spe

282 ding potential (BPND) obtained from the full kinetic analysis was compared with the SUVR and with non

283 residue impacts the L-glutaminase property, kinetic analysis was coupled with crystal structure dete

284 In this article, the reliability of the kinetic analysis was improved by obtaining steady-state

285 Third, a preliminary kinetic analysis was performed using the radiometabolite

286 Kinetic analysis was performed with the radiometabolite-

287 Reaction progress kinetic analysis was performed, shedding light on a poss

288 KIF3A and KIF3B stepping, a presteady-state kinetic analysis was pursued.

289 A sigmoidal response kinetic analysis was used to calculate both the diffusio

290 Reaction progress kinetic analysis was used to obtain insight into the mec

291 Reaction progress kinetic analysis was utilized to determine kinetic profi

292 Using real-time kinetic analysis we show that mcm(5)-modified tRNA(Lys)

293 ingle-molecule fluorescence measurements and kinetic analysis, we find that the reaction in solution

294 ents, chemical shift perturbation and enzyme kinetic analysis, we provide structural insights into th

295 The results of kinetic analysis were confirmed by chronocoulometry meth

296 rast, decreasing time-activity curves in the kinetic analysis were highly prognostic for shorter prog

297 Site-directed mutagenesis and kinetic analysis with substrate analogs revealed the rol

298 ction and to compare parameters derived from kinetic analysis with SUV ratio (SUVR) calculated over d

299 Results of kinetics analysis with synthetic fluorogenic peptides in

300 The transient kinetic analysis without OM demonstrates that F764L has