ライフサイエンスコーパス: knowledge of

1 les of genes can be discovered without prior knowledge of a biological network, instead training a de

2 his is the first description in yeast to our knowledge of a cis-translated protein interacting with a

3 Thus, knowledge of a potential structural dependence (single-

4 the algorithms are optimized for biological knowledge of a specific type.

5 ironmental toxicology studies, and increased knowledge of Ahr-mediated responses to xenobiotics is im

6 g the general population is low, with a poor knowledge of alcohol consumption and dietary guidelines.

7 Our current knowledge of allostery is principally shaped by a struct

8 Our knowledge of amyloid formation and cytotoxicity originat

9 Our knowledge of ancient human population structure in sub-S

10 Here, we integrate knowledge of animal sensory ecology, physiology and life

11 We present an overview of current knowledge of antifungal T cell immune responses, with em

12 tiple times independently among vertebrates, knowledge of associated immune system adjustments is res

13 In this Review, we summarize the emerging knowledge of B cells across the NSAb-mediated diseases.

14 ome structure of E. faecalis now extends our knowledge of bacterial ribosome structures and may serve

15 Much of our current knowledge of biological chemistry is founded in the stru

16 These significantly matched current knowledge of biological pathways and predicted future on

17 Researchers worldwide are combining their knowledge of biology, medicine, tissue engineering, and

18 In this Review, we appraise the current knowledge of blood pressure genomics, explore the causal

19 ological process would aid in our collective knowledge of both carbon cycling and microbial strategie

20 Knowledge of both pH and [OCl(-)] is essential for deter

21 Here, I broadly frame our current knowledge of Brachypodium-virus interactions and how the

22 ances in molecular biology are deepening our knowledge of CAM evolution.

23 the intention to follow a LCD, while higher knowledge of carbohydrate, and agreeing with national di

24 ts high rates of chromosomal aberrations and knowledge of causative mechanisms would represent an imp

25 Despite this fundamental split, our current knowledge of cellular and molecular mechanism driving ro

26 s that are predominately male, thus limiting knowledge of cerebral growth in females with ASD.

27 hnaswamy have closed an important gap in our knowledge of coagulation factor X activation by the intr

28 We summarize current knowledge of common familial CRC, provide an update on s

29 cluding cell-type-specific markers and prior knowledge of compositions, in the estimation procedure.

30 ilico tools were used to expand our chemical knowledge of compounds observed in superfood samples.

31 This observation adds to our growing knowledge of cooperative group behavior and its importan

32 Knowledge of CRC in cancer is fundamental to understandi

33 Knowledge of cytokine-receptor interaction (CRI) is very

34 We then applied our structural knowledge of DabA and a homologous enzyme from the kaini

35 observed for one secondary outcome variable: knowledge of diabetic retinopathy (p = .03) with moderat

36 Yet, knowledge of disease incidence is important for clinicia

37 ness of drugs that may cause arrhythmias and knowledge of distinct arrhythmias that may be drug-induc

38 To increase the knowledge of diversity of carbohydrate structures within

39 s typically use descriptors constructed from knowledge of either the full crystal structure - therefo

40 However, integrated molecular knowledge of EN subtypes is lacking.

41 on of such materials as well as foundational knowledge of energetic science new to most chemists.

42 s of probe optimization without any a priori knowledge of enzyme targets and has the potential to be

43 s in understanding corresponds to increasing knowledge of experimental and implicit chemical variable

44 Central to such strategies is knowledge of extreme event probabilities.

45 theme that experimental approaches based on knowledge of feedforward signals have promoted greater u

46 trol infection information using generalized knowledge of filarial transmission dynamics, monitoring

47 Knowledge of fundamental differences between breast canc

48 However, knowledge of gene essentiality under optimal growth cond

49 integrates multiple data types and external knowledge of gene function to detect candidate genes, ap

50 ck of current genetic studies is the limited knowledge of gene-environment interaction.

51 Our results highlight gaps in our current knowledge of genetics and molecular mechanisms of comple

52 Whilst knowledge of genomic sequences in crops is increasing ra

53 Understanding evolution requires detailed knowledge of genotype-phenotype maps; however, it can be

54 Improved knowledge of GM2 gangliosidosis in adults will help clin

55 Knowledge of growth rates and growth patterns is useful

56 gnostic, and therapeutic approaches based on knowledge of gut microbiota are needed.

57 athological lung lipid composition, previous knowledge of healthy lung tissue lipid composition is es

58 t risk; however, for many rare entities, our knowledge of heritable predisposition is incomplete.

59 While knowledge of highly structured regions is integral for m

60 ntal question in immunology, we utilized our knowledge of HIV-1 dynamics to compare the kinetics of t

61 have developed ten KCs of EDCs based on our knowledge of hormone actions and EDC effects.

62 Here, we review the current knowledge of how age and systemic metabolic state affect

63 ly increasing anthropogenic nitrogen inputs, knowledge of how ammonia oxidation (AO) in the ocean res

64 The hope is that integrating knowledge of how bone marrow niches contribute to haemat

65 nderstanding and mitigating threats requires knowledge of how demographic processes operate throughou

66 Yet knowledge of how effectively these movements shift gaze

67 This finding advances our knowledge of how ganglion neurons generate uncharacteris

68 nscriptomic approach to gain a more detailed knowledge of how mating might transpire.

69 in biological applications is predicated on knowledge of how MoS(2) interacts with ultrafast (< 1 ps

70 However, our knowledge of how nasal colonization impacts on the lung

71 s crucial but difficult owing to our limited knowledge of how regulatory elements function.

72 use of autophagy induction requires detailed knowledge of how the disease affects the autophagy-lysos

73 In this Review, we discuss the current knowledge of how these different Pol II stalling context

74 cur during ageing and the rapidly increasing knowledge of how these epigenetic mechanisms have an eff

75 Furthermore, knowledge of how these processes differ between the embr

76 ndow of opportunity for advancing scientific knowledge of how X chromosome gene imprinting, epigeneti

77 regulation, which significantly revisits our knowledge of HTLV-1 pathogenesis and other NF-kappaB-rel

78 These findings expand our knowledge of IGF-1's role as a novel fibrotic-switch, br

79 This review highlights our current state of knowledge of immune mechanisms and targeted immunomodula

80 ution, translating high-throughput data into knowledge of immune mechanisms has been challenged by th

81 athologic events in lesional skin has led to knowledge of important cell populations and transcriptio

82 ase advanced faster after listeners acquired knowledge of incoming speech.

83 of large mammal extinctions requires greater knowledge of individual species' histories and their ada

84 Knowledge of infiltrating endometriosis and its ultrason

85 With the current knowledge of influenza A virus (IAV), we designed a nano

86 Given current knowledge of IP(3)Rs, we develop a model describing the

87 s largely due to an increasing physiological knowledge of its effects and to its being used in combin

88 However, knowledge of its environmental fate has been very limite

89 SVC has important clinical implications, and knowledge of its imaging appearance and hemodynamics is

90 ts ubiquitous use in medicine, and extensive knowledge of its molecular and cellular effects, how ane

91 However, knowledge of K. pneumoniae ecology, population structure

92 f different screening programs given current knowledge of key COVID-19 life history and epidemiologic

93 enced enormous progress based on the growing knowledge of key mediators in severe CRSwNP.

94 new neurodiagnostic insights to the current knowledge of Leigh syndrome, including association with

95 ation subscale, R3KT) and religious (Islamic Knowledge of Living Organ Donation, IK-LOD) living kidne

96 ruction applications require a comprehensive knowledge of local-scale signals, which can threaten the

97 data naturally encapsulates the broad expert knowledge of many individual surveyors spread throughout

98 ile safeners have been utilized for decades, knowledge of mechanisms that induce gene expression is l

99 hol's acute neural effects could augment our knowledge of mechanisms underlying alcohol-related cogni

100 These findings expand our fundamental knowledge of microbial reductive dehalogenation and warr

101 A) modeling, each of which leverage a priori knowledge of molecular subtypes of tumors or drug MOA fo

102 the ingestion of MPs by deep-sea fauna, but knowledge of MPs' fate once ingested still remains scant

103 ed, but suffused with the extensive clinical knowledge of our forebears.

104 this region could substantially increase our knowledge of P-Rex1 signaling and open the door to new s

105 analysis and investigation into the current knowledge of p75NTR signaling networks and pathways.

106 Our knowledge of patient-related factors influencing the occ

107 Our review summarizes the current knowledge of pediatric clinical disease, role in transmi

108 Our current knowledge of pelagiphages is based on a few studies and

109 Recent studies have added greatly to our knowledge of peroxisomes, addressing areas such as the d

110 This requires an accurate knowledge of phylogenetic relationships, which have ofte

111 provided by sampling with plankton nets, our knowledge of plankton distributions at these edges is li

112 neering is currently hindered by our limited knowledge of plant cis-regulatory elements.

113 Our knowledge of pluripotent stem cell (PSC) biology has adv

114 Knowledge of potential insertion points from TRIAD libra

115 s in FBS subcomponents and the effect of the knowledge of presence of atherosclerosis as assessed by

116 Building on knowledge of previous outbreaks of SARS-CoV-1 and Middle

117 Filling a gap in the current knowledge of protective antigens in humans, our data sup

118 Knowledge of protein corona composition, formation mecha

119 Knowledge of protein-binding residues (PBRs) improves ou

120 tilized proteomic techniques to progress our knowledge of protein-mediated pathways within the rumen

121 igands towards PSA is critical for expanding knowledge of PSA interactions and achieving selective gl

122 ry videos represent a significant advance in knowledge of psylloid anatomy and are useful tools for f

123 without causing cellular death requires the knowledge of radiation dose tolerance at very small tiss

124 EZ) to interpret these findings from current knowledge of radiological dose-response relationships, h

125 Knowledge of receptor usage and homology models may be u

126 The method does not require prior knowledge of reference genomes and produces highly accur

127 l eye in summarizing current epidemiological knowledge of refugee youth mental health as well as inte

128 d bottom-up approaches and yield more robust knowledge of regional CO(2) budgets.

129 This Tansley insight summarizes our current knowledge of regulation of tonoplast Na(+) -permeable ch

130 Here we provide an update of the current knowledge of RGS2 function as it relates to molecular me

131 Knowledge of right ventricular (RV) function has lagged

132 rate rapidly increasing amounts of data, the knowledge of robust data-driven modelling methods profes

133 Knowledge of rotational energy transfer (RET) involving

134 is article provides an update on the current knowledge of sepsis in immunocompromised patients withou

135 To identify such patients we aimed to use knowledge of sepsis response subphenotypes based on tran

136 To expand our knowledge of sequence determinants of IDP phase separati

137 e of Eurocentric genetic studies and limited knowledge of shared causal variants.

138 s a composite phenotype that expands genetic knowledge of smoking.

139 Equipped with a better knowledge of SOICs' multifunctional properties, research

140 ions that exploit multi-mode fibers, a prior knowledge of spatial mode structure of the fiber, in pri

141 h that leads to new species discoveries, new knowledge of species relationships, and the refinement o

142 Improved knowledge of species' responses to climate dynamics will

143 greatly depends on the investigator's prior knowledge of specific compound classes and their mass sp

144 Thus, this study increases the knowledge of specific myeloid subsets involved in the pa

145 This study adds to our knowledge of spinning apparatus variability in modern sp

146 s that must be addressed in order to use our knowledge of splicing to guide the diagnosis and treatme

147 Together with the knowledge of strong associations between EAT and cardiac

148 s exploit richer information associated with knowledge of task dynamics.

149 consistent with a role in encoding long-term knowledge of task structure.

150 hold more dear than, or value so much as, my knowledge of the actions of great people, acquired by lo

151 ) the perspective of the addressee or 3) the knowledge of the addressee about the target objects' loc

152 Despite considerable advances in knowledge of the anatomy, ecology and evolution of early

153 lation in Alzheimer disease (AD), but to the knowledge of the authors the association with tau burden

154 sts differ by physician specialty is, to the knowledge of the authors, not known.

155 It deepened our knowledge of the biochemical underpinnings of numerous d

156 experimental work that supports our current knowledge of the biochemistry, molecular mechanisms, and

157 Most of our knowledge of the biological basis of major depressive di

158 By combining our knowledge of the biological features of the virus with c

159 Advances in our knowledge of the biology of axSpA will settle some diffe

160 echanistic insights substantially extend our knowledge of the cell signals that function in concert t

161 m of this Review is to summarize our current knowledge of the cell-to-cell transmission of pathologic

162 inated by the human brain for centuries, yet knowledge of the cellular and molecular events that buil

163 y the CeA.SIGNIFICANCE STATEMENT Our current knowledge of the circuit organization within the central

164 Knowledge of the CMC is not only of practical relevance

165 This work deepens knowledge of the CO electrooxidation process and provide

166 ntargeted and therefore do not require prior knowledge of the composition or genetic diversity of HLA

167 rgeon workload is poorly studied with little knowledge of the contributing factors impacting workload

168 argely restricted to outbreaks, limiting our knowledge of the contribution of sporadic illness to the

169 Although knowledge of the coordination chemistry and metal-withho

170 The knowledge of the correlation of the concentration of eac

171 Yet, our knowledge of the coupling between species range shifts a

172 An appropriate MRCP protocol and knowledge of the different findings that are characteris

173 this review, we detail the current state of knowledge of the different signalling pathways coupled t

174 A wide gap exists between our knowledge of the disease and a promising treatment or cu

175 Yaravirus expands our knowledge of the diversity of DNA viruses.

176 This work consequently suggests that the knowledge of the DNA-binding properties of the proteins

177 This is partly caused by the yet incomplete knowledge of the effect of genetic and environmental var

178 Knowledge of the entry receptor is key to understand SAR

179 Knowledge of the environmental timescales for survival o

180 pectral unmixing (SSASU) algorithm that uses knowledge of the estimated endmembers to learn the autof

181 Knowledge of the etiology of cutaneous lupus is rapidly

182 rs of the main groups of eukaryotes, and our knowledge of the evolution of chromatin-related processe

183 fforts of the global research community, our knowledge of the factors that lead to the development of

184 al and statistical cues but also their prior knowledge of the form of language.

185 Knowledge of the full repertoire of cardiac cells and th

186 ng these challenges requires a more detailed knowledge of the fundamental biology of AAV as well as c

187 y-curated database compiling our accumulated knowledge of the genes and mutations that underlie natur

188 Knowledge of the genetic architecture of importantly agr

189 With growing knowledge of the genetic basis of atherosclerotic cardio

190 ces in genomic technologies have transformed knowledge of the genetic basis of phaeochromocytoma and

191 Improved knowledge of the genetic basis of traits can facilitate

192 Collectively, these data expand our knowledge of the genetic circuits that are involved in t

193 r sequencing have led to an explosion in our knowledge of the genetic complexity of cancer.

194 (AIRR-seq) currently rely on our incomplete knowledge of the genetic diversity at HLA and BCR/TCR lo

195 In conclusion, the growing knowledge of the genetic relationship between T2D and CH

196 This review summarizes the current knowledge of the genetics and candidate modifier genes i

197 esses the question of whether this expanding knowledge of the genomics of T2D provides insight into t

198 der a well-chosen perturbation with accurate knowledge of the imaging system, we can robustly measure

199 This Review discusses our current knowledge of the immune response in thyroid cancers, the

200 EGFR has been extensively investigated, our knowledge of the initiation and maintenance of EGFR sign

201 to be answered to successfully translate our knowledge of the intestinal microbiome and the changes a

202 A greater knowledge of the intricate cellular milieu of the heart

203 Knowledge of the intrinsic variability of radiomic featu

204 ble logistic regression was used to evaluate knowledge of the LCOD.

205 This review summarises the knowledge of the life cycle of this therapeutic target,

206 In this Review, we summarize current knowledge of the links between HIV-1 infection and immun

207 The DCI concept provides basic knowledge of the magnitude of factors affecting the bioa

208 oung's modulus of the matrix without further knowledge of the matrix deformations surrounding the cel

209 r or inhibitor is likely to be benefitted by knowledge of the mechanism that gives rise to coupling.

210 These findings further our knowledge of the mechanisms commensal microbes use for n

211 Nevertheless, our knowledge of the mechanisms governing the developmental

212 Altogether, a deeper knowledge of the mechanisms involved in the ischaemic de

213 This review aims to summarize the current knowledge of the mechanisms underlying spontaneous intes

214 the development of resources to advance our knowledge of the mechanisms, diagnosis, management, and

215 rstanding human skin aging requires in-depth knowledge of the molecular and functional properties of

216 ugs and vaccines are hampered by the limited knowledge of the molecular details of how SARS-CoV-2 inf

217 (S)) mouse, research has generated extensive knowledge of the molecular mechanisms underlying Walleri

218 evelopment has long been recognized, but our knowledge of the molecular, genetic and epigenetic requi

219 Moreover, we add to the knowledge of the morphology of the skull roof, rostrum a

220 d related factors is recommended to increase knowledge of the mothers on their children's care in add

221 amics based folding simulations that rely on knowledge of the native structure can provide critical,

222 taining an aromatic chromophore requires the knowledge of the nature and energy level of low-lying ex

223 implement, as they typically assume complete knowledge of the network structure, which is unusual in

224 poses containing a homo-dimer without prior knowledge of the number (n) of monomers.

225 Our increasingly detailed knowledge of the oak genome and of oak interspecific and

226 While the current knowledge of the oral microbiome is constantly expanding

227 ill be instrumental in greatly expanding our knowledge of the origins and variation of genes governin

228 st efforts have accumulated a vast wealth of knowledge of the ORR on extended Pt and Pt-alloy model s

229 Finally, we discuss how knowledge of the p53 pro-survival and pro-death decision

230 To accumulate knowledge of the pathological mechanisms behind the cond

231 ets and is in better accord with the current knowledge of the pathophysiology of the disease.

232 Knowledge of the pathways involved in the response of ma

233 These findings extend our knowledge of the pathways underlying HF and may inform n

234 ific and sensitive assay by including a deep knowledge of the physicochemical properties of these pep

235 ach profile, suppressing bias from imprecise knowledge of the point spread function.

236 as been uncertain in part because of limited knowledge of the precursor emissions and the chemical en

237 We believe that the radiologist's knowledge of the prevalence and pattern of occurrence of

238 n presented with a metastatic tumour without knowledge of the primary.

239 Knowledge of the prognostic factors of PCa and the bone

240 Despite this association, our knowledge of the progression of the initial viral infect

241 ess of fixed volumes of fluid, this requires knowledge of the protocol before the design of the chip.

242 Knowledge of the refractive history significantly improv

243 This study allowed a deep knowledge of the regioselectivity of the reaction, which

244 Knowledge of the relationship between kidney dysfunction

245 s mechanisms and their optimization requires knowledge of the relativistic electron dynamics and the

246 Our knowledge of the repertoire of S-acylated proteins has b

247 We argue that knowledge of the reproductive microbiome is fundamental

248 ijuana use and legalization without adequate knowledge of the risks necessitate the characterization

249 ndividual localizations without ground-truth knowledge of the sample.

250 paper, we will critically review our current knowledge of the secondary effects caused by FUS-BBB ope

251 Here, we discuss current knowledge of the signals that coordinate Treg cell devel

252 t drive intra-mammalian development requires knowledge of the spatial organisation and transcriptiona

253 Data and knowledge of the spatial-temporal dynamics of surface wa

254 These findings highlight how knowledge of the specific characteristics of resistance

255 , unclear mechanisms of action and a lack of knowledge of the specific roles and regulation of mitoch

256 However, there is limited knowledge of the specific transcriptional and signaling

257 ortant role in sensor NLR-mediated immunity, knowledge of the specific, redundant, and synergistic fu

258 sts (humans, both sexes), we show that it is knowledge of the speed-contrast association that account

259 Knowledge of the spike glycoprotein evolution, function

260 icircles and gRNAs in T. lewisi broadens our knowledge of the structure and expression of the mitocho

261 In this review, I focus on our current knowledge of the structure and molecular composition of

262 sooner if a serious adverse event requiring knowledge of the study drug occurred.

263 te at microscopic scales or require a priori knowledge of the target location for 3D imaging.

264 phila and provide biochemical data to extend knowledge of the Thi5 enzyme, the corresponding biosynth

265 physiologically relevant animal models, our knowledge of the trafficking signals displayed by distin

266 materials and guide future molecular design, knowledge of the transition from molecular properties in

267 d registered a protocol with PROSPERO before knowledge of the trial results (CRD42019132669).

268 ication of their modification extent without knowledge of the types of modifications involved.

269 rgeted therapy is lacking due to our limited knowledge of the underlying cellular and molecular mecha

270 atic individuals relative to current medical knowledge of the virus and mitigation measures.

271 d when humans use language to organize their knowledge of the world in categorical semantic represent

272 Knowledge of their 3D structures is critical to understa

273 Nevertheless, the knowledge of their chemistry is still very limited compa

274 Knowledge of their community dynamics is key to understa

275 The rarity of these neoplasms, the limited knowledge of their driving defects and the lack of exper

276 Our knowledge of their fundamental biology is limited by ava

277 for imaging of PPGL patients with or without knowledge of their genetic background.

278 that modulate gene expression; however, our knowledge of their implications in the divergence of bac

279 these solvents in industrial processes, the knowledge of their molecular organization and thermophys

280 In this review, we provide knowledge of these cancers with frequent perineural inva

281 Knowledge of these characteristics may be useful in comm

282 The discovery of XP advances our knowledge of these important human viruses and opens an

283 sitive interactions has been far outpaced by knowledge of these important relationships in terrestria

284 Knowledge of these parameters has been proven to be of g

285 Knowledge of these structural motifs and binding mode sh

286 inally, we highlight the missing gaps in our knowledge of these systems in females.

287 Over the past decade, our knowledge of this link has grown significantly.

288 Knowledge of this new PVAT function supports PVAT as an

289 ology and vectorial capacity will enrich our knowledge of tick-borne infections.

290 lular therapy, without the need for a priori knowledge of tumor antigen, ex vivo cellular manipulatio

291 onse was achieved without requiring a priori knowledge of tumor-expressed antigens and reflects the t

292 Therapeutically, knowledge of type 3 immunity has translated into the dev

293 The stabilizer does not require knowledge of user intent and can outperform supervised r

294 Knowledge of varied imaging appearances of HAE is essent

295 Here, we review current knowledge of VGCC regulation and function in nonexcitabl

296 Approaches for cure are lacking, and the knowledge of virus-host interactions is still limited.

297 We leverage the knowledge of well-established cancer driver genes to def

298 iling ctDNA almost invariably requires prior knowledge of what genomic alterations to track.

299 raphical memory, which prevents experimenter knowledge of what information is being retrieved, and wh

300 f their promoter motifs, as well as accurate knowledge of which genes are expressed when and the amin