ライフサイエンスコーパス: laboratory strain

1 d with similar specificities as those of the laboratory strain.

2 higher fraction of the population than in a laboratory strain.

3 pecies, and C. psittaci Cal10, a widely used laboratory strain.

4 idative stress significantly better than the laboratory strain.

5 into the 5'-flanking region of CYP6B8 in the laboratory strain.

6 with the same kinetics as H37Rv, a virulent laboratory strain.

7 N* effects on antibiotic susceptibility in a laboratory strain.

8 iffers from the closely related E. coli K-12 laboratory strain.

9 that different isoforms are modified in each laboratory strain.

10 nic mosquitoes relative to the untransformed laboratory strain.

11 strain CFT073 that is absent from an E. coli laboratory strain.

12 s and compared results to the nontransformed laboratory strain.

13 onfer PZA resistance when reconstructed in a laboratory strain.

14 , but researchers typically use one standard laboratory strain.

15 netic background, which differs from that of laboratory strains.

16 om the "smooth" colonies typically formed by laboratory strains.

17 a sets composed of almost 200 distinct mouse laboratory strains.

18 gins and substructure of these commonly used laboratory strains.

19 me amplification and sequencing using common laboratory strains.

20 that describes the lineage of commonly used laboratory strains.

21 equencing in a common subset of 12 classical laboratory strains.

22 lved the manipulation of individual genes in laboratory strains.

23 SA and those of hospital-associated MRSA and laboratory strains.

24 ant allele is present in multiple C. elegans laboratory strains.

25 ese SNPs are valid resistance markers in the laboratory strains.

26 ffered from that previously determined using laboratory strains.

27 , a self-adherence phenotype lacking in most laboratory strains.

28 een found among wild isolates and created in laboratory strains.

29 -gp120-blocking Ab activity measured against laboratory strains.

30 tic treatment and could be reassociated with laboratory strains.

31 missing from a number of common high passage laboratory strains.

32 These variant loci distinguish laboratory strains.

33 ates are more hypercyanogenic than nonmucoid laboratory strains.

34 neralizing the results of studies based upon laboratory strains.

35 ifferences observed is found among classical laboratory strains.

36 as in immunodeficient mice but not in common laboratory strains.

37 Tcf7l2 and wild-type females from 30 inbred laboratory strains.

38 inishing reference genomes for commonly used laboratory strains.

39 ributed in a mosaic pattern among the extant laboratory strains.

40 2 structural variants among 39 commonly used laboratory strains.

41 most in independent populations of the same laboratory strains.

42 wild-derived populations and inbred isogenic laboratory strains.

43 tbreak, differ significantly from the common laboratory strain 10403S.

44 sequences of 34 HSV-2 low-passage-number and laboratory strains, 14 of which were collected in Uganda

45 Previous work has shown that the laboratory strain 168 forms markedly attenuated biofilms

46 Laboratory strain 3153A and two C. albicans strains isol

47 clinical isolate SD90e from South Africa or laboratory strain 333.

48 teins of chondroitin sulfate A (CSA)-binding laboratory strains (3D7-CSA and FCR3-CSA) and a clinical

49 The commonly used Staphylococcus aureus laboratory strain 8325-4 bears a naturally occurring 11-

50 with TX WT and our previously characterized laboratory strain A/PR/8/34 (PR8) and its NS1 knockout s

51 Conversely, the spherical laboratory strain A/Puerto Rico/8/1934 (H1N1) was passag

52 eosinophil responses to the virus using the laboratory strain (A/PR/08/1934) or the pandemic strain

53 variation in recombination rate among common laboratory strains, a result that carries important impl

54 way mucin expression than infection with RSV laboratory strain A2.

55 heliotropic strain VR1814 and the attenuated laboratory strain AD169 in human placental villi as expl

56 ere than those seen with a Delta97 mutant of laboratory strain AD169, which harbors extensive deletio

57 When UL133/8 was restored to HCMV laboratory strain AD169, which otherwise lacks the locus

58 Here, we utilized two laboratory strains (AD169 and Towne) of human cytomegalo

59 ith a clinical CMV strain, VR1814, but not a laboratory strain, AD169, downregulates MMP activity in

60 n with the hallmarks of latency, whereas the laboratory strains, AD169 and Towne, replicated producin

61 n addition to an extended bacterial panel of laboratory strains, all 3 molecules rapidly accumulated

62 RME1 that affects sporulation efficiency in laboratory strains also cosegregates with significant ph

63 A 3-day-old biofilm either a laboratory strain (American Type Culture Collection [ATC

64 Both a laboratory strain and a clinical isolate of C. albicans

65 The laboratory strain and most other S. pombe strains contai

66 y two genomes have been determined, the HG52 laboratory strain and the newly sequenced SD90e low-pass

67 0 domains blocked mosquito transmission of a laboratory strain and two field isolates using an ex viv

68 ions was identified in the lpd gene of the 5 laboratory strains and 13 clinical isolates.

69 or amplifications are a prominent feature of laboratory strains and appear to have originated under l

70 Indeed, supernatants from laboratory strains and clinical isolates of S. aureus ca

71 shown to be associated in PAS resistance in laboratory strains and clinical isolates.

72 e biofilm formation by Staphylococcus aureus laboratory strains and clinical isolates.

73 d by inflammasome activation induced by both laboratory strains and clinical isolates.

74 hat CDF can support the long-term culture of laboratory strains and demonstrate that this formulation

75 PIA (PIA-AMV) induced mucoidy in both these laboratory strains and early lung colonizing non-mucoid

76 Among 16 laboratory strains and field isolates, the extent of fac

77 00 high-quality SNPs in 631 Pf isolates from laboratory strains and four malaria-endemic regions (Wes

78 This effect was observed in laboratory strains and in clinical isolates from a recen

79 trate that a rare population of HSV, both in laboratory strains and in primary clinical isolates from

80 lls using a panel of wild-type P. falciparum laboratory strains and invasion ligand knockout lines, a

81 sh genomes, representing three commonly used laboratory strains and one native population, we constru

82 displayed potent antiviral activity against laboratory strains and primary isolates of T- and M- tro

83 hanced specific ADCML of HIV-1 virions (both laboratory strains and primary isolates) and provirus-ac

84 e challenge this dogma by showing that yeast laboratory strains and strains isolated from grapes unde

85 e biofilm-forming abilities of the prototype laboratory strains and the currently circulating isolate

86 d susceptible (FANG) and resistant (FUMOZ-R) laboratory strains and the hybrid strains showed interme

87 We found that all laboratory strains and the majority of field strains tes

88 ho did mechanistic research using homozygous laboratory strains and those who studied patterns of gen

89 it is detected during infections with three laboratory strains and two low-passage clinical isolates

90 rgely predicts fusibility within and between laboratory strains and wild-type isolates.

91 -fixed whole cells of C. perfringens HN13 (a laboratory strain) and JGS4143 (chicken isolate) intramu

92 We adapted E. faecalis OG1RF (a laboratory strain) and S613TM (a clinical strain) lackin

93 pyrG sequences were identical to one of the laboratory strains, and an additional 12% (6/51) differe

94 0 also contains an 80-kb plasmid absent from laboratory strains, and mutations in a plasmid-encoded h

95 (UL128 to UL150) that are largely mutated in laboratory strains, and recent studies have indicated th

96 Five of the eight founders are common laboratory strains, and three are wild-derived.

97 rotein encoded by NL4-3, a widely used HIV-1 laboratory strain, antagonizes human BST-2 but not monke

98 We show that classical laboratory strains are derived from a few fancy mice wit

99 ation that exists among wild mice, classical laboratory strains are derived from a limited set of fou

100 Haploid laboratory strains are enabling a deep integration of cl

101 Although laboratory strains are extremely sensitive to aneuploidy

102 ak and also indicate that currently utilized laboratory strains are imperfect models for studying L.

103 Although laboratory strains are restricted to growth in fibroblas

104 fficult to measure because mating tests with laboratory strains are usually required to identify C. e

105 usly reported to be required for swarming in laboratory strains, are dispensable for robust swarming

106 ction procedure and occurred in a variety of laboratory strains as well as a freshly obtained clinica

107 This gH complex is notably missing from HCMV laboratory strains as well as HCMV vaccines previously e

108 t and have achieved excellent results in two laboratory strains as well as in evolved Ty1 high-copy s

109 We present data for laboratory strains, as well as pfcrt transfectants expre

110 as expressed in controls and in F. nucleatum laboratory strain ATCC cocultures throughout the epithel

111 disseminated isolates (RST3), and a standard laboratory strain (B-31) were established in a murine cy

112 Separate models were developed for laboratory strain bacteria cultured in the laboratory an

113 esent in clinical samples and in widely used laboratory strains (BH10), and it profoundly affects HIV

114 with adaptive evolution were detected in the laboratory strain, but they do not account for the major

115 RpoN* reduces virulence of P. aeruginosa laboratory strains, but its effects in clinical isolates

116 gene and quantitative trait locus studies of laboratory strains, but with greater availability of gen

117 genome of CBS 2777 is related to that of the laboratory strain by a complex chromosome rearrangement.

118 The three laboratory strains carried the Xpr1(n) receptor variant

119 Some strains, including most laboratory strains, carry an allele of GPA1 (an upstream

120 mes (ORFs) in the genomic DNA of C. albicans laboratory strains carrying one (CAI-4) to three (BWP17)

121 Laboratory strains carrying pMB2 grew faster than isogen

122 Laboratory strains, cell lines, and other genetic materi

123 in the central core sequences present in the laboratory strain centromeres, but lack adjacent heteroc

124 by use of 2 representative MRSA strains: the laboratory strain COL and the community-acquired clinica

125 Many S. cerevisiae strains, including common laboratory strains, contain only a partial biotin synthe

126 Haemolytic activity in the mutant laboratory strains could be restored by the addition of

127 ed placentas as well as those from different laboratory strains could bind to CSPG but not to HA.

128 y, we found that one of our Escherichia coli laboratory strains (CS109) harbors a missense mutation i

129 imbriae in UPEC cystitis isolate F11 and the laboratory strain E. coli K-12 MG1655 also resulted in d

130 y infection of these cell types because HCMV laboratory strains (e.g., AD169 and Towne) have lost the

131 in human AM in response to infection with a laboratory strain, early and late clinical isolates of P

132 A laboratory strain engineered to carry this mutation did

133 ion of the potassium and proton pumps in the laboratory strain enhances performance to levels exceedi

134 idual female Drosophila from a highly inbred laboratory strain exhibit idiosyncratic odor preferences

135 icated strains of Bacillus subtilis, but not laboratory strains, exhibit robust swarming motility on

136 h level of genome instability in C. albicans laboratory strains exposed to the stress of transformati

137 , we obtained the genome sequences of both a laboratory strain (F) and a low-passage clinical isolate

138 recombination into a cloned cytomegalovirus laboratory strain, followed by reporter-based yield redu

139 compared with strain Erdman, a commonly used laboratory strain for studies of pathogenesis.

140 t wild mice will be a valuable complement to laboratory strains for studying the genetics of complex

141 epsC, swrA, and degQ, the resulting repaired laboratory strain forms biofilms that are as robust as a

142 North America more closely resemble the HG52 laboratory strain from Scotland than the low-passage-num

143 compared with other clinical strains and the laboratory strain H37Rv.

144 lates and its env gene cloned into the NL4-3 laboratory strain had similar fitness, and both were mor

145 tilis, surfactin disrupted vesicles while in laboratory strains harbouring a mutation in the gene sfp

146 RNAs from infected animal tissues or from laboratory strains have been reverse transcribed, amplif

147 Some laboratory strains have been sub-cultured for decades si

148 In addition, these two laboratory strains have been suggested to express very d

149 es utilizing prototypical EBV type 1 (EBV-1) laboratory strains have generally failed to readily infe

150 ools for plant molecular biologists, current laboratory strains have remained unchanged for decades a

151 However, the antecedents of today's laboratory strains have undergone extensive mutagenesis

152 In both clinical S. aureus isolates and laboratory strains, high Sak-producing strains formed le

153 While laboratory strains (HIV-1NL4.3 and HIV-1IIIB) are sensit

154 1 and PreXMRV-2 were found together in three laboratory strains, Hsd nude, NU/NU, and C57BR/cd, consi

155 revious studies of the Escherichia coli K-12 laboratory strain identified a group of effector protein

156 ies biofilms formed by clinical isolates and laboratory strains in the presence and absence of clinic

157 n increase of 0.35 sternopleural bristles in laboratory strains in two large samples of wild-caught D

158 six isolates replicated as well as standard laboratory strains in vitro.

159 s and ethanol fermentation in commercial and laboratory strains (including a xylose-fermenting strain

160 Linear plasmid 25, which is often lost in laboratory strains, is required for the infection of mic

161 E. faecalis isolates, the well-characterized laboratory strain JH2-2 and a human-derived fecal isolat

162 his serogroup, but there are 3 commonly used laboratory strains: L pneumophila serogroup 1 Philadelph

163 clinical HCMV isolates, extensively passaged laboratory strains lack the UL/b' region and hence do no

164 been performed with even the most conserved laboratory strains, let alone the highly divergent prima

165 ortant topic areas in Candida biology; and a laboratory strain lineage page that describes the lineag

166 Two prophages found in the common laboratory strain LT2 were absent.

167 pathogenic strain 14028 but not in avirulent laboratory strain LT2.

168 rived macrophages (BMDMs) were infected with laboratory strain M. tuberculosis H37Rv or clinical isol

169 heckerboard screens were performed using the laboratory strain M. tuberculosis H37Rv, lead spectinami

170 rom laboratory isolates revealed that mucoid laboratory strains made sevenfold more HCN than their no

171 one of the most divergent from the canonical laboratory strain N2 and has been widely used in develop

172 Using the laboratory strain N2, we identify a novel C. elegans inn

173 ecombinants derived from a cross between the laboratory strain (N2) and a wild strain (CB4856).

174 spread dosage compensation occurs neither in laboratory strains nor in natural variants of S. cerevis

175 t of mature biofilms formed by the sequenced laboratory strain of B. bronchiseptica We hypothesized t

176 When approximately 10(8) CFU/ml of a laboratory strain of B. pertussis was cultured in vitro,

177 ow that this phenomenon occurs not only in a laboratory strain of E. coli, but also in a natural isol

178 inical isolate had a growth advantage over a laboratory strain of E. faecalis in the kidneys but not

179 strain, we identified a mutation in the main laboratory strain of EBV that impairs virus function, an

180 marsh water enhanced photoinactivation of a laboratory strain of Enterococcus faecalis, but depresse

181 Here, using a laboratory strain of Enterococcus faecalis, we developed

182 because its expression in a serum-sensitive laboratory strain of Escherichia coli conferred both of

183 on system, but none of its effectors, into a laboratory strain of Escherichia coli is sufficient to p

184 ped a synthetic genetic system that allows a laboratory strain of Escherichia coli to sense and kill

185 ns and show that they can be reproduced in a laboratory strain of Escherichia coli.

186 Exposure of an avirulent laboratory strain of H. capsulatum to A. castellanii sel

187 t in the genomes of a midgut cell line and a laboratory strain of H. zea.

188 Based on the comparison of derivatives of a laboratory strain of Haemophilus influenzae expressing e

189 epair of the mutated UL131 gene in the AD169 laboratory strain of HCMV restored its ability to infect

190 ically inhibited replication of an R5-tropic laboratory strain of HIV in a multicycle infection assay

191 Here, we show that a laboratory strain of mouse (Mus musculus, C57BL/6J) robu

192 We show that DEP and H37Ra, an avirulent laboratory strain of Mycobacterium tuberculosis, were bo

193 rchy of inhibitory activity against the NF54 laboratory strain of P. falciparum in Anopheles stephens

194 and possible industrial manipulations of the laboratory strain of yeast could have had a strong effec

195 y in Bacillus subtilis, and we reassert that laboratory strains of B. subtilis do not swarm.

196 acid), the siderophore precursor produced by laboratory strains of B. subtilis, is of secondary impor

197 For example, domesticated laboratory strains of Bacillus subtilis are renowned for

198 Previous studies of laboratory strains of budding yeast had shown that when

199 s between the genotypes of two commonly used laboratory strains of D. melanogaster (Canton-S and Oreg

200 interleukin-6 (IL-6) and IL-8 in response to laboratory strains of E. coli in vitro.

201 Importantly, O antigen production enables laboratory strains of E. coli to enter the gut of the Ca

202 ated by XO activity was effective at killing laboratory strains of E. coli, commensal microbiotas, an

203 zed and stabilized in recipient clinical and laboratory strains of Enterobacteriaceae bacteria.

204 Laboratory strains of Escherichia coli and P. aeruginosa

205 exerts antibacterial effects on clinical and laboratory strains of Escherichia coli and report that d

206 ynthesis has been studied most thoroughly in laboratory strains of Escherichia coli and Salmonella en

207 ynthesis is coordinated with vesiculation in laboratory strains of Escherichia coli to yield glycosyl

208 data resource that integrates information on laboratory strains of Escherichia coli, its phages, plas

209 LS activity using heterologous expression in laboratory strains of Escherichia coli.

210 degree of conservation in clinical isolates, laboratory strains of HCMV, and even in chimpanzee CMV.

211 voxilaprevir susceptibility of clinical and laboratory strains of HCV was assessed.

212 cells (HFLC) reliably support infection with laboratory strains of hepatitis C virus (HCV), although

213 n immunodeficiency virus type 2 (HIV-2), and laboratory strains of HIV-1.

214 ng highly resistant to infection with common laboratory strains of influenza A virus.

215 ll four TMA tests were determined using nine laboratory strains of M. genitalium and 56 nontarget bac

216 hibitor clavulanate, potent activity against laboratory strains of M. tuberculosis was observed [mini

217 V-A59) demonstrated replication identical to laboratory strains of MHV-A59 in tissue culture; however

218 Commercially available laboratory strains of mice are not readily infected by S

219 In comparisons to published studies of laboratory strains of mice that were artificially select

220 ut do not cause similar disease in wild-type laboratory strains of mice unless first adapted to these

221 However, MmuPV1 failed to grow in common laboratory strains of mice with an intact immune system.

222 NVs) in homozygous organisms, such as inbred laboratory strains of mice, from short read sequence dat

223 found that minocycline was highly potent in laboratory strains of Mycobacterium tuberculosis and tha

224 rily from detailed studies on a few selected laboratory strains of Mycobacterium tuberculosis, Mycoba

225 on transformation and DNA uptake for several laboratory strains of N. gonorrhoeae.

226 n inhibition assays on clinical isolates and laboratory strains of P. falciparum in the presence of a

227 Here, we measured invasion of laboratory strains of P. falciparum relying on distinct

228 sion regulation between natural variants and laboratory strains of S. cerevisiae, we evaluated the ka

229 Distributions of polymorphisms in laboratory strains of S. rosetta provided independent ev

230 Genetically modified laboratory strains of Saccharomyces cerevisiae are exten

231 However, laboratory strains of SB can be rendered neurovirulent f

232 Cell culture-adapted laboratory strains of Sindbis virus (SB) exhibit efficie

233 12 field isolates and eight commonly studied laboratory strains of the model organism Chlamydomonas r

234 However, laboratory strains of the virus, many of which were deve

235 Consistent with previous findings using laboratory strains of the virus, the mutant replicated n

236 Here, we demonstrate that two commonly used laboratory strains of the yeast Candida albicans, CAI-4

237 f CRISPR-Cas9 gene drive systems in wild and laboratory strains of the yeast Saccharomyces cerevisiae

238 w this is not just a property of vaccine and laboratory strains of virus, because an association betw

239 in Vero cells infected with three different laboratory strains of wild-type HSV-1.

240 for Corneal Ulcers Trial (SCUT) and for two laboratory strains, PA103 and PAO1.

241 molecular basis for such differences in two laboratory strains, PAK and PAO1.

242 E. coli laboratory strains, particularly E. coli K-12, are far f

243 h recurrent bottlenecks in the S. cerevisiae laboratory strain population.

244 We used both the laboratory strain PR8 and a set of viruses engineered to

245 at are prevented from replicating within the laboratory strain Pseudomonas aeruginosa PA14 by the end

246 -i5 and A32) strongly reacted to three HIV-1 laboratory strains (R5, X4, and R5/X4), six primary isol

247 ants expressing different amounts of PcsB in laboratory strain R6 and virulent serotype 2 strain D39

248 In contrast, laboratory strain R6 contains 71 single-base-pair change

249 In contrast, laboratory strain R6 contains suppressors that allow the

250 4, a recent serotype 4 clinical isolate, and laboratory strain R6, an avirulent, unencapsulated deriv

251 l mechanistic complications in commonly used laboratory strain R6.

252 ogroup 19 middle ear strain 5093 against the laboratory strain R6.

253 these genes compared to the sequenced model laboratory strain RB50, a rabbit isolate.

254 own, however, whether hotspots identified in laboratory strains reflect the hotspot diversity of natu

255 rA mutation, as well as the mutation in sfp, laboratory strains regained the capacity to swarm and di

256 In contrast, wild-derived laboratory strains represent a broad sampling of diversi

257 Larvae from a laboratory strain resistant to Cry1Ac and Cry2Ab in diet

258 e RSV line 19 strain but not with the RSV A2 laboratory strain results in lung IL-13 and mucus expres

259 he viral strain EBV WIL, which unlike common laboratory strains retains intact noncoding regions wher

260 hat mutation of traP in the prototype 8325-4 laboratory strain RN6390 results in reduced expression o

261 ransformation experiments with the sensitive laboratory strain S. pneumoniae R6 as recipient.

262 brid diploids formed by outcrossing with the laboratory strain S288c also displayed good spore viabil

263 the phenotypic spectrum: the widely studied laboratory strain S288C and the vineyard isolate RM11-1a

264 Expression of the gene FLO1 in the laboratory strain S288C restores flocculation, an altere

265 oid segregants from a cross between a common laboratory strain (S288c) and a clinically derived strai

266 tionary rates in the lineages leading to the laboratory strain (S288c) and a wild strain (YJM789) of

267 a mutation found in the progenitor standard laboratory strain (SLS) and all previous sequences that

268 relative to those of a wild-type serotype O1 laboratory strain (stO1).

269 ion at each gene predicts allorecognition in laboratory strains such that colonies reject if they do

270 foscarnet resistance when incorporated into laboratory strain T2294.

271 myces cerevisiae and found that genes in the laboratory strain tend to evolve faster than in the wild

272 lococcus aureus strain RN4220, a widely used laboratory strain that carries a nitrosoguanidine (MNNG)

273 arch in this field uses a few dozen standard laboratory strains that are reported to share a common a

274 By use of clinical and laboratory strains that had been exposed to vancomycin,

275 We find that laboratory strains that show little differences in drug

276 icological tests may be biased by the use of laboratory strains that usually contain very limited gen

277 Unlike wild-type laboratory strains, the desert strain fails to respond t

278 ne population was an insecticide-susceptible laboratory strain; the other two populations originated

279 of human RasGAP NF1, in commonly used axenic laboratory strains, this gene is mutated and inactive.

280 rk adds to elegant studies in the sensitized laboratory strain to present a mechanistic understanding

281 d sufficient to explain the inability of the laboratory strain to produce robust biofilms.

282 tionally, we analyzed diversity in zebrafish laboratory strains to find areas of elevated diversity a

283 The failure of laboratory strains to swarm is caused by a mutation in a

284 Pfs47 modulates resistance of some parasite laboratory strains to TEP1-mediated killing.

285 siae tolerate chromosome amplification while laboratory strains used as a model for aneuploid syndrom

286 xpressing wild-type deltasg, or the standard laboratory strain w(1118), Drosophila expressing deltasg

287 nctional in wild aneuploids but defective in laboratory strain W303.

288 This collection, which was generated with a laboratory strain, was screened for mutants that were im

289 visiae strain, the PCA1 allele of the common laboratory strains we have examined possesses a missense

290 Using a panel of five mutant laboratory strains, we show the effect of the Mitf gene

291 gainst 7 heterologous primary isolates and 1 laboratory strain were compared between 32 untreated HIV

292 Laboratory strains were found to harbour a frameshift mu

293 the nearly 60 years since the first standard laboratory strains were isolated, numerous crosses and e

294 ratory and wild mouse strains, we found that laboratory strains were predominantly selected for passi

295 additional ExPEC strains, but not an E. coli laboratory strain, were also capable of survival within

296 The AD169 laboratory strain, which lacks a functional UL131 protei

297 UP proteoforms expressed in the urine of two laboratory strains, Wistar Han and Brown Norway, and wil

298 t was surprising to detect that VZV32, a VZV laboratory strain with no discernible growth defect in t

299 pic evaluation of clinical isolates and of a laboratory strain with the rtI233V mutation demonstrated

300 ious lesions, which is extensively used as a laboratory strain worldwide.