ライフサイエンスコーパス: labyrinth

1 molecule to pass through the given chemical labyrinth.

2 iadne is the legendary Minoan goddess of the Labyrinth.

3 native splice forms in the HCs of vestibular labyrinth.

4 lve fine anatomic detail in vitro, as in the labyrinth.

5 and prevented the formation of the placental labyrinth.

6 ith a thin and poorly vascularized placental labyrinth.

7 can also exist as an entity confined to the labyrinth.

8 lial cells in the cochlea and the vestibular labyrinth.

9 structuring of the otocyst to form a complex labyrinth.

10 ntained numerous maternal blood pools in the labyrinth.

11 le of TF in the maintenance of the placental labyrinth.

12 ant for regeneration/repair in the mammalian labyrinth.

13 tyly), and dysmorphogenesis of the placental labyrinth.

14 a of the crista ampullaris of the vestibular labyrinth.

15 dac6 during differentiation of the placental labyrinth.

16 e maternal-foetal interface in the placental labyrinth.

17 of sudden insight about the structure of the labyrinth.

18 ructures and depends on an intact vestibular labyrinth.

19 e fetal-facing SCTB layer in mouse placental labyrinth.

20 othelial cells specifically in the placental labyrinth.

21 oietic markers, and localize to the vascular labyrinth.

22 uclear inflammatory cells into the placental labyrinth.

23 ormation normally provided by the vestibular labyrinth.

24 otransmitters were found only in the carotid labyrinth.

25 d with trophoblastic cells in the interphase labyrinth.

26 ment focusing on the exchange interface, the labyrinth.

27 nonsensory elements of the adult membranous labyrinth.

28 al embryos, as well as in E13.5 yolk sac and labyrinth.

29 lation of the neurosensory epithelium in one labyrinth.

30 ion of the spongiotrophoblast layer into the labyrinth.

31 ased size and malformation of the membranous labyrinth.

32 opology of the accessible part of a chemical labyrinth.

33 2% [50/131]), skin (38.2% [50/131]), ear and labyrinth (30.5% [40/131]), nervous system (20.6% [27/13

34 ed defective vasculogenesis in the placental labyrinth, a collapsed endocardium, and impaired vessel

35 loss of the diploid spongiotrophoblasts and labyrinth and an expansion of the polyploid giant cell l

36 PRV transport from the vestibular labyrinth and cervical muscles also resulted in CNS infe

37 ions of separate retrograde tracers into the labyrinth and into the floccular and ventral parafloccul

38 unconstrained behavior of mice in a complex labyrinth and measure the dynamics of learning and the b

39 chymal remodeling that forms the mature bony labyrinth and regulates inductive signaling mechanisms i

40 A knockout mice made earlier, that displayed labyrinth and yolk sac-specific defects, but our finding

41 ual reconstructions of plesiosaur endosseous labyrinths and the first large-scale, quantitative study

42 ional (1D) sinusoidal wrinkles, herringbone, labyrinth, and checkerboard.

43 blood vessels failed to invade the placental labyrinth, and in the embryo proper, where defective blo

44 model implementing these feedbacks, circles, labyrinths, and islands form when sorting dominates; pol

45 from the two labyrinths even though a single labyrinth appeared capable of signalling 3-D head motion

46 he aorta, pulmocutaneous artery, and carotid labyrinth appears to reflect a phylogenetic transition b

47 cells and a severe disruption of the normal labyrinth architecture in the placenta.

48 roscopy analysis revealed that this aberrant labyrinth architecture was associated with disrupted bas

49 ymphatic duct and swelling of the membranous labyrinth are common features in Gbx2-/- inner ears.

50 g the development of the membranous and bony labyrinths are largely unknown.

51 Turtle labyrinths are relatively larger than those of mammals,

52 These smaller labyrinths are well described by a family of patterns th

53 Gestational hypoxia decreased labyrinth area, increased the incidence of red blood cel

54 bited a phenotype characterized by increased labyrinth area, reduced Epcam expression (marker of laby

55 imaeroid specializations, including the otic labyrinth arrangement and the brain space configuration

56 lium of the otic pit, otocyst and membranous labyrinth as they underwent morphogenesis.

57 PLET1 expression in trophoblast cells of the labyrinth, as well as in spongiotrophoblast and glycogen

58 n in the stria vascularis and inducing blood-labyrinth barrier (BLB) hyperpermeability, along with ch

59 alin-dependent AG transport across the blood-labyrinth barrier identifies new therapeutic targets for

60 ouse model with noise-induced cochlear blood-labyrinth-barrier (CBLB) injury, we examined the effects

61 Unlike the placental labyrinth, basement membranes and vasculogenesis were no

62 ress polar patterns but rather stabilize the labyrinth, bimeron and bubble phases within a wider rang

63 interface, as well as a severe disruption of labyrinth branching morphogenesis.

64 morphogenesis, widespread penetration of the labyrinth by spongiotrophoblasts, and abnormal distribut

65 here we produce tortuous thermal paths (i.e. labyrinths) by introducing slits to control the impact o

66 ion about it and associated structures (e.g. labyrinths) can be obtained from the cranial endocast.

67 that connects the endolymphatic sac and the labyrinth cavity.

68 bird-like degree of brain flexion and a bony labyrinth comparable in shape to those of many crown bir

69 er ear revealed a collapse of the membranous labyrinth, consistent with a critical role for NKCC1 in

70 A mature inner ear is a complex labyrinth containing multiple sensory organs and nonsens

71 mics of the inner ear fluids, and membranous labyrinth deformability.

72 hat the proper organization of the placental labyrinth depends on coordinated inter-endothelial repul

73 s in neural tube closure, abnormal placental labyrinth development associated with loss of epithelial

74 irmed that lethality was due to a failure of labyrinth development, and this correlates exactly with

75 d for monosynaptic input from the vestibular labyrinth, direct projection to the oculomotor nucleus a

76 us adverse events in the category of ear and labyrinth disorders.

77 We hypothesize that a reduction in bony labyrinth disparity is indicative of the underlying gene

78 Transient inactivation of the intact labyrinth elicited the lateralized behaviour described b

79 etween the two syncytial layers of the mouse labyrinth, ensuring the correct establishment of the pla

80 eg muscles receive equal inputs from the two labyrinths even though a single labyrinth appeared capab

81 Sauropterygian labyrinth evolution is therefore correlated closely with

82 The HAI-1(-/-) placental labyrinth exhibited a complete failure of vascularizatio

83 ibited reduced fetal vessel branching in the labyrinth, failed SA remodeling and reendothelialization

84 inating individual canal input from the left labyrinth following right nVIII block, which indicated t

85 chorionic trophoblasts and enabled placental labyrinth formation and development to term.

86 spongiotrophoblast layer, and an absence of labyrinth formation causing an improper vascularization

87 nt1), which regulates BCT cell integrity and labyrinth formation.

88 g this biological setting into the 'Ant-in-a-Labyrinth' framework which studies physical transport th

89 We use four recently-discovered bony labyrinths from the site of Kromdraai to significantly e

90 semicircular canals (SCCs) of the endosseous labyrinth has a long-hypothesized relationship with loco

91 roaches, many questions remain, and the bony labyrinth has shown considerable potential for the phylo

92 Lesions of the entire vestibular labyrinth have been shown to severely alter VIIIth nerve

93 edictions for the critical curves separating labyrinth, hybrid and hexagonal phases.

94 rin-2 labeling of structures in the cortical labyrinth in a pattern similar to that of the Na(+)-Ca2+

95 ibly inactivating the intact contra-lesional labyrinth in compensating animals through superfusion of

96 accumulation of endolymph in the membranous labyrinth in the inner ear.

97 munoreactivity was present in the vestibular labyrinth, in stromal cells underneath the non-immunorea

98 arent in the otic capsule and the membranous labyrinth, including ectopic and fused sensory patches.

99 igible effect on components of the placental labyrinth, including the two syncytial cell layers, but

100 the firing of vestibular afferents from each labyrinth independently and measured the resulting balan

101 In addition, the vascular labyrinth is disorganized, with thickening of the matern

102 Efferent innervation of the vestibular labyrinth is known to be cholinergic.

103 , the endolymphatic duct, and the membranous labyrinth is poorly developed.

104 rcolation theory and prove that whenever the labyrinth is solvable, a logarithmically small sensing r

105 The placental labyrinth is the interface for gas and nutrient exchange

106 ex organ rudiment, the developing membranous labyrinth, is initiated.

107 The placental labyrinth (L) had a higher sO2 than the junctional zone

108 l portion of the placenta, in particular the labyrinth (LA), displays strong overlapping expression o

109 also developed abnormally, showing a thinner labyrinth lacking embryonic erythrocytes and blood vesse

110 oliferation and increase in apoptosis in the labyrinth layer and both unchanged in the junctional zon

111 ys postcoitum as nearly complete loss of the labyrinth layer and significant reduction of the spongio

112 entas display lack of vascularization of the labyrinth layer as well as increased rates of apoptosis,

113 The labyrinth layer failed to form properly in the majority

114 n of placental morphogenesis at the stage of labyrinth layer formation and occurs in the absence of o

115 emonstrated a drastic disorganization of the labyrinth layer in the placenta of Rb-deficient embryos,

116 subset of trophoblast within the chorion and labyrinth layer of the mouse placenta.

117 nd that the ESX1 protein is expressed in the labyrinth layer of the placenta in vivo, where its subce

118 ssed in the syncytiotrophoblast cells of the labyrinth layer of the placenta, and the epithelial cell

119 condarily causing collapse of the underlying labyrinth layer.

120 , most notably in the spongiotrophoblast and labyrinth layers.

121 erstitial (epithelial) cells in type-II, and labyrinth-like infolding structures opening towards the

122 ng topology, supported by calculations, is a labyrinth-like pattern with two orthogonal periodic modu

123 common feature of all transfer cells is the labyrinth-like wall-in-growth (WIG) that increases the p

124 A mouse in the labyrinth makes ~2000 navigation decisions per hour.

125 ghout lungfish evolution, and changes in the labyrinth may potentially reflect a change from nektonic

126 We developed and optimized a novel Labyrinth microfluidic device to efficiently isolate CTC

127 The bony labyrinth might contribute to this debate, as it display

128 ffects of increasingly aquatic lifestyles on labyrinth morphology among marine reptiles.

129 We analyze the evolution of labyrinth morphology and its ecological drivers in livin

130 Finally, aspects of endosseous labyrinth morphology are remarkably similar between dive

131 it septation, neural tube closure, placental labyrinth morphology, lung lobe septation, hair growth,

132 After formation of the membranous labyrinth, Nor-1 expression in the vestibule is limited

133 data, we here describe the endocast and bony labyrinth of Brindabellaspis stensioi from the Early Dev

134 rs superior of the otocyst to form a complex labyrinth of cavities and ducts is blocked, as indicated

135 le ectodermal patch, the inner ear becomes a labyrinth of chambers housing six to eight sensory organ

136 al thickening called the otic placode into a labyrinth of chambers which house sensory organs that se

137 e vertebrate inner ear consists of a complex labyrinth of epithelial cells that is surrounded by a bo

138 the inner ear is sculpted into this complex labyrinth of fluid-filled ducts punctuated by their asso

139 earch in this area can provide glimpses of a labyrinth of genetic architectures that have rarely been

140 Recent studies suggest a labyrinth of receptor kinase-cyclic nucleotide-gated ion

141 on the vestibular hair cells located in the labyrinth of the dogfish Scyliorhinus canicula, and find

142 The membranous labyrinth of the inner ear establishes a precise geometr

143 tructure of the cochlea, part of the osseous labyrinth of the inner ear, is now one of the most frequ

144 egulate the concentration of iron within the labyrinth of the inner ear, which might indirectly tune

145 nsory receptors, known as hair cells, in the labyrinth of the inner ear.

146 which collectively constitute the membranous labyrinth of the inner ear.

147 surface area of the exchange barrier in the labyrinth of the mouse placenta to be reduced and thickn

148 ect attention at navigating the multifaceted labyrinth of the neurohormonal model that has led to the

149 glutamate immunoreactivity in the vestibular labyrinth of the oyster toadfish by using whole end orga

150 GFP expression at E11.5 to E13.5 in both the labyrinth of the placenta and the yolk sac.

151 showed high expression of TCblR/CD320 in the labyrinth of the placenta, embryonic brain, and spinal c

152 SP9/MKP-4 in the trophoblast giant cells and labyrinth of the placenta.

153 cellular flux of interstitial fluid into the labyrinth of the salivary duct.

154 The labyrinth of the vertebrate inner ear is a sensory syste

155 ize themselves into a carefully sculpted, 3D labyrinth of vessels that regulate blood flow throughout

156 Using uCT scans, we examined bony labyrinths of a broad sample of various carnivoran speci

157 ing whether a molecule can traverse chemical labyrinths of channels, tunnels, and buried cavities usu

158 First, the membranous labyrinths of mouse inner ears ranging from 10.25 to 17

159 Paint-filled membranous labyrinths of Otx1-/- mutants showed an absence of the l

160 ts into potential differences among the bony labyrinths of Plio-Pleistocene hominins may inform their

161 bryonic vasculature and heart, the placental labyrinths of these embryos exhibited aberrant alignment

162 the inner ear by paint-filling of membranous labyrinths of Whl/+ embryos.

163 idual, as well as the inner ears (endosseous labyrinths) of one other adult and several juveniles (th

164 ones that can pass through a given chemical labyrinth or screen chemical labyrinths to identify thos

165 ells are closely related to the basal lamina labyrinths or fractones derived from subependymal microg

166 It has osteological correlates of a labyrinth organ, which in extant climbing perches gives

167 ng electrode placed unilaterally on the bony labyrinth overlying the posterior canal (PC).

168 ause it is impractical to test each molecule/labyrinth pair using computationally expensive methods,

169 nism underlying development of the placental labyrinth, particularly in terms of its endothelial orga

170 ow known physical solutions to the 'Ant-in-a-Labyrinth' problem.

171 th Map3k4 in trophoblast stem (TS) cells and labyrinth progenitors, whereas Hdac6 expression is highe

172 We conclude that both labyrinths provide independent estimates of head motion

173 The results demonstrate that the bony labyrinth provides a powerful ecological proxy reflectin

174 The labyrinths range from straight nanobeams with a complete

175 towards the midgestational expansion of the labyrinth region while maintaining the thin layer of tro

176 Orientation of the osseous labyrinth relative to the long axis of the skull was dif

177 entrally compact, anteroposteriorly elongate labyrinths, resembling those of crocodylians.

178 motor output because stimulation of just one labyrinth revealed a power law relationship between stim

179 Antigenic targets of autoimmunity within the labyrinth seem to be diverse.

180 Central hypotheses predict that labyrinth shape and size are related to ecological adapt

181 w that Capreolinae are more variable in bony labyrinth shape than Cervinae and confirm for the first

182 We also find that labyrinth shape variation does not correlate with ecolog

183 ng the widespread expectation that reptilian labyrinth shapes convey behavioral signal, and demonstra

184 contrast, plesiosaurs have compact, bulbous labyrinths, sharing some features with those of sea turt

185 Recent experiments with mice navigating a labyrinth show a sharp discontinuity during learning, co

186 used to look for acoustic neuromas, abnormal labyrinth signal intensity or enhancement, and brain dis

187 ilic deposits in the cochlear and vestibular labyrinths, similar to protein aggregation in well-known

188 Differences in relative labyrinth size among sauropterygians correspond to locom

189 many birds, undermining the hypothesis that labyrinth size correlates directly with agility across v

190 mong plesiosaurs coincide with reductions of labyrinth size, paralleling the evolutionary history of

191 bioelectronic devices to interface with the labyrinth, spanning the vestibular implant and artificia

192 ns form a pair of chiral enantiomeric gyroid labyrinths (srs nets) over a broad range of compositions

193 promised after destruction of the vestibular labyrinths, suggesting that the extraretinal signals nee

194 f the olfactory apparatus and the endosseous labyrinth suggests that olfaction, hearing, and equilibr

195 ective placentas, with significantly reduced labyrinth surface area and blood vessel vascularization.

196 [5, 6] placodonts have proportionally larger labyrinths than actively swimming taxa (i.e., all other

197 We show that turtles have unexpectedly large labyrinths that evolved during the origin of aquatic hab

198 have been located previously in the carotid labyrinth, the aortic arch, and the pulmocutaneous arter

199 two syncytial layers of the mouse placental labyrinth, the Syncytiotrophoblast-I lineage, initially

200 nic ectoderm, as well as in the yolk sac and labyrinth tissues that form later.

201 The relative contributions of each labyrinth to behavior, as well as how the brain recovers

202 tance of the conformal perilymph-filled bony labyrinth to pressure changes and to high frequency soun

203 given chemical labyrinth or screen chemical labyrinths to identify those that allow a given molecule

204 Further, at E19.5 labyrinth trophoblast had reduced glucose transporter 1

205 We identified an Epcam(hi) labyrinth trophoblast progenitor (LaTP) in mouse placent

206 of transcription factors GATA2 and GATA3 in labyrinth trophoblast progenitors (LaTPs) have underdeve

207 th area, reduced Epcam expression (marker of labyrinth trophoblast progenitors), altered maternal blo

208 xpressed markers of both junctional zone and labyrinth trophoblast subtypes in a manner comparable to

209 lacenta that at a clonal level generates all labyrinth trophoblast subtypes, syncytiotrophoblasts I a

210 rtension and liver damage, promoted abnormal labyrinth vascularization in the placenta, and decreased

211 duced definitive erythropoiesis in placental labyrinth vasculature.

212 gain in high-fidelity LTM capability for the Labyrinth-VR arm, relative to placebo, which reached the

213 uter game play over four weeks in either the Labyrinth-VR or placebo control game arms.

214 irtual reality (VR) spatial wayfinding game (Labyrinth-VR) as a cognitive intervention with the hypot

215 f the lateral semicircular canal of the bony labyrinth was aligned horizontally.

216 ta ampullaris, and the membranous vestibular labyrinth was collapsed.

217 in these regions that give rise to the bony labyrinth was complementary to TR expression in the sens

218 Additionally, the volume fraction of the labyrinth was reduced, as was the surface area for mater

219 gus nerve, whereas only cells in the carotid labyrinth were innervated by the glossopharyngeal nerve.

220 Bony labyrinths were digitally reconstructed and measurements

221 s influenced the evolution of the endosseous labyrinth, which houses the vestibular sensory organ of

222 eficiency in the arterioles of the placental labyrinth, which leads first to flow reversal in the umb

223 e incidence of red blood cells (RBCs) in the labyrinth while expanding the placental spiral arteries

224 Any perturbation in the structure of the labyrinth will undoubtedly lead to functional deficits.

225 formation of a uniform sheet of cells into a labyrinth with multiple cell types.

226 rocess involves distortion of the membranous labyrinth with the formation of endolymphatic hydrops.

227 The labyrinths within the gyroid film are densely packed and

228 Signals from the bilateral vestibular labyrinths work in tandem to generate robust estimates o

229 pes involved in development of the placental labyrinth zone and trophoblast invasion.

230 There was a significant decrease in the labyrinth zone and vasculature of the placenta, which co

231 g in reduced endothelial cell density at the labyrinth zone at E17.5.

232 ch may be a result of the adversely affected labyrinth zone development.

233 -derived cell subtypes in the junctional and labyrinth zones of the placenta.

234 On GD21, male and female placental labyrinth zones were collected for mitochondrial respiro

235 ved placental compartment (junctional and/or labyrinth zones) at E11.5, as judged by i) increased lev

236 yed structural changes in the junctional and labyrinth zones, along with increased placental glycogen