ライフサイエンスコーパス: lack

1 droxyl group that 99% of other AAA+ proteins lack.

2 urance receive maintenance dialysis has been lacking.

3 suitable reference genes in these subsets is lacking.

4 re being reported, but comprehensive data is lacking.

5 , and mechanisms of carbapenem resistance is lacking.

6 tional relevance in human satellite cells is lacking.

7 ic changes caused by heterochromatin loss is lacking.

8 ively halogenate pyridine C-H precursors are lacking.

9 ics of leukocytes non-invasively in vivo are lacking.

10 y regulated genes and associated networks is lacking.

11 rmation, key to optimizing these devices, is lacking.

12 geting for therapeutic application have been lacking.

13 rly regulatory functions of the dynamins are lacking.

14 iagram tool with full functionality is still lacking.

15 nderstanding of why they are so effective is lacking.

16 ed spin ladder) in a magnetic field is still lacking.

17 ends specific to an infection area have been lacking.

18 ion at county scale across mutiple years are lacking.

19 randomized data that test this paradigm are lacking.

20 nments, but the tools to test its limits are lacking.

21 emerge at particular points in time has been lacking.

22 ts remember from alcohol-related episodes is lacking.

23 ver, studies including treatment details are lacking.

24 for the coexistence of condensed phases are lacking.

25 cterisation of speed representation is still lacking.

26 arkers of response to systemic therapies are lacking.

27 nformation that connects these structures is lacking.

28 hanges in virulence attenuation is currently lacking.

29 leads to the development of colon cancer is lacking.

30 nism between ischemia and Abeta toxicity are lacking.

31 ivity across this brainstem-wide circuit are lacking.

32 l synthesis of their effects on hydrology is lacking.

33 ogenetic resolution or clear apomorphies are lacking.

34 or primary prophylaxis in these patients are lacking.

35 ransplanted for primary immunodeficiency are lacking.

36 of how Msp1 extracts its substrates is still lacking.

37 es of large NAFLD-associated HCC cohorts are lacking.

38 's order, but empirical evidence for this is lacking.

39 rate and broadly applicable models are still lacking.

40 resolution and blood flow-resolving speed is lacking.

41 l of isoform-selective enzyme modulation are lacking.

42 ly multiclass classification tasks are still lacking.

43 However, these tools lack a comprehensive pipeline that includes both pre-GWA

44 We therefore lack a consolidation of the mechanisms by which socialit

45 middle-income countries and existing studies lack a description of the methods used to harmonize the

46 dictable environments, however, we currently lack a rigorous, mechanistic examination of how plastici

47 established over the last century, we still lack a solid framework from which to investigate more ab

48 So far, we are lacking a comprehensive stability analysis of the Antarc

49 DHBc variants lacking a folding-proficient extension produced regular

50 d the quantification threshold and therefore lacking a measurement of expression.

51 1) is a life-threatening pathogen that still lacks a curative therapy or vaccine.

52 improve psychological well-being, the field lacks a unifying framework that clarifies the dimensions

53 ttenuated telomeric DNA damage response that lacks accompanying telomere fusions, and propagate for m

54 e-based adjuvant, the gB ectodomain protein (lacking AD-3) with squalene adjuvant, or lipid nanoparti

55 ite is similar to that in Y-SiO(2) but which lacks adjacent hydroxyl groups, and are 7 times more act

56 Tissues from mice lacking ADTRP (Adtrp-KO), or both AIG1 and ADTRP (DKO) h

57 fic and CD11c-specific knockout ((-/-)) mice lacking AhR, respectively, in LC and Langerin(+) dermal

58 Thus, we developed mice that lack all of the TRPCs and performed a transcriptome anal

59 T-cell-mediated disease, was induced in mice lacking all 3 immunoproteasome subunits (triple-ip(-/-))

60 y, inhibition of L-type VGCCs, but not GluA2-lacking AMPARs or ryanodine receptors, was required to r

61 ever, current MHC-binding prediction methods lack an analysis of the major conformational states and

62 ands of leviviral genomes, but most of these lack an annotated sgl, mainly due to the small size, lac

63 Nevertheless, we still lack an economical and highly stable chitinase enzyme fo

64 ne catalogue is essentially complete, but we lack an equivalently vetted inventory of bona fide human

65 vel odor-reward association, whereas the pPC lacks an explicit representation even after weeks of ove

66 However, STEAP1 lacks an intracellular NADPH-binding domain and does not

67 red MSCs were undetectable within grafts and lacked anchoring fibril reconstitution.

68 a high-quality reference genome is currently lacking, and the group's evolutionary history is not ful

69 patients with spontaneous cerebellar ICH are lacking, and the risk of bias in published series is hig

70 because they express alpha-Gal epitopes and lack anti-Gal Abs.

71 Lacking appropriate computational methods, information h

72 ogenitors, a more restricted progenitor type lacking attachment to the basal lamina.

73 obular appendages are present in mutant mice lacking BCs, implying that although synchronized with BC

74 toimmune phenotype was recapitulated in mice lacking beta1,6N-acetylglucosaminyltransferase V (Mgat5)

75 We show that mice lacking both DLL1 and DLL4 in adult beta-cells display i

76 Strains lacking both pilins are resistant to a broad panel of SS

77 diabetic leptin receptor-mutant mice to mice lacking CaMKIIdelta globally.

78 extinguished conditioned fear in rodents and lacked cardiac and behavioral side effects, suggesting i

79 (2) Ni(p)(I) (g( ) > g(||) ~ 2) surprisingly lacks CO.

80 Transplastomic plants were produced that lacked cognate Se Rubisco small subunits (SSU) and expre

81 orks (Su, PARACELSUS, Delphi); however, they lack consensus, and their performance has not yet been v

82 Many adults with comorbid conditions lacked critical knowledge about COVID-19 and, despite co

83 However, SARS-CoV-2 sera generally lacked cross-neutralization to a highly homologous pre-e

84 More than 70% of the UHGG species lack cultured representatives, and 40% of the UHGP lack

85 Cells lacking cyclin B can enter mitosis and phosphorylate mos

86 Glomeruli of patients with FSGS lack DAF and stain positive for C3d, and urinary C3a pos

87 the putative PC-1/PC-2 polycystin complex is lacking due to technical hurdles in reliably measuring i

88 Adenovirus mutants lacking E1B55K or E4orf6 display defects in viral RNA pr

89 sis (Arabidopsis thaliana) knock-out mutants lacking either phot2 or chup1 and analyzed the kinetics

90 mmunoproteasome subunits (triple-ip(-/-)) or lacking either the gene encoding LMP2 and LMP7 by immuni

91 is fitness advantage was absent in mice that lacked epithelial NADPH oxidase 1 (NOX1) activity.

92 ual environment that provided optic flow but lacked explicit position cues.

93 associated with chronic infection, yet they lack expression of many virulence determinants associate

94 , prepared prior to germ layer induction and lacking extraembryonic tissues, can specify all germ lay

95 l HER performance of NiO is still limited by lacking favorable H adsorption sites.

96 story strategies in deep-sea environments is lacking for many species of fishes.

97 lly with regards to alternative splicing-are lacking for most primary cell types, including platelets

98 stakeholder-recommended core outcome set is lacking for pediatric critical care outcomes.

99 ultured representatives, and 40% of the UHGP lack functional annotations.

100 Strikingly, mice and flies lacking functional autophagy develop early onset progres

101 HSV-1 that lacks gC was more sensitive to complement-independent ne

102 We show that mutant strains lacking gigC have impaired growth in the absence of the

103 Here, we show that keratinocytes lacking hemidesmosomal integrin alpha6beta4 exhibit incr

104 levated in the prostates harvested from mice lacking HO-1 in myeloid compartment.

105 cued by re-expressing WT but not ChREBP that lacks hydroxylated prolines in ChREBP-deleted hepatocyte

106 d infection, approximately one in 16 persons lacked IgG antibodies.

107 beta-Ga(2)O(3) and other existing materials lack in response time and stability at elevated temperat

108 ity, water and wastewater services are still lacking in many colonias.

109 lyses in gaseous samples which are of course lacking in supporting electrolytes.

110 s do not include CXC subfamily complexes and lack information about the receptor distal N-termini, de

111 The MEDI3726 protein scaffold lacks interchain disulfide bonds and has an average drug

112 D3A and ATAD3C, the protein product of which lacks key functional residues.

113 tentiate WNT/beta-catenin signaling in cells lacking leucine-rich repeat-containing G-protein coupled

114 eq quantification tools tailored for TEs are lacking, limiting our ability to dissect TE expression d

115 characterized function of mtFAS, as mutants lacking lipoylation have an intact ETC.

116 However, most projections lack long-term observations incorporating the potential

117 profile and occlusion is often difficult and lacks long-term stability, it becomes important to unrav

118 Importantly, mice lacking Ly6e in immune cells were highly susceptible to

119 ors, and established systemic treatments are lacking.METHODSWe used next-generation sequencing and ar

120 gnosed pulmonary tuberculosis (PTB) patients lack microbiological evidence of Mycobacterium tuberculo

121 4 or Aim2 inflammasomes were intact in cells lacking Mm47.

122 ponse downstream of TLR4 was intact in cells lacking Mm47.

123 from the thymus, Tregs in regressing plaques lacked Nrp1 expression, suggesting that they are induced

124 sortment process has been constrained by the lack of a coherent, model-based inference framework.

125 lineate, owing to its lineage complexity and lack of a concise genetic definition.

126 ts actual range is not well known due to the lack of a formal description until recent times (2006) a

127 grades of arrested retinal development with lack of a foveal pit and no cone photoreceptor outer seg

128 rains associated with Washington state, with lack of a predominant lineage and limited transmission a

129 resistant pathogens can be attributed to the lack of a rapid pathogen identification (ID) or antimicr

130 F response between HBV genotypes B and C and lack of a single pattern of mutations among intra-host v

131 ese genes has not been undertaken due to the lack of a stable transformation system.

132 Lack of access to testing and concern regarding suboptim

133 Delayed or lack of action on implementation would push back the tim

134 nce similarity, low agonist selectivity, and lack of activation and G protein-coupling knowledge have

135 Lack of adherence (nonadherence) or undertreatment (nonp

136 olecular details remain unclear owing to the lack of an analytical method for global detection of pro

137 rch has been greatly hindered because of the lack of an animal model.

138 The lack of an effect of ligands, the formation of carbon-ce

139 ized deep networks predict well, despite the lack of an explicit complexity control during training,

140 Until now, there has been a lack of analytical methods that can reliably verify the

141 and underrepresented in research due to the lack of animal models.

142 was admitted to our hospital for high fever, lack of appetite related to nausea and vomiting, headach

143 However, the lack of appropriate probes to bridge both microscopic re

144 of noncompositionally robust measures, and a lack of attention to social factors as confounders or ef

145 n patients older than 3.8 years included the lack of availability of outpatient ultra-widefield FA (U

146 ropical deforestation affects climate is the lack of baseline conditions (i.e., prior to human distur

147 Therefore, the lack of BBSome function negatively impacts retinal synap

148 ropathogenesis remain elusive, mainly due to lack of brain-representative experimental systems to stu

149 laceae, Ruminococcaceae), but no significant lack of butyrogenic bacteria.

150 Conversely, lack of CD137L on T cells enhanced their diabetogenic ac

151 ensors has, however, been limited due to the lack of cell-specific targeting methods in brain tissue

152 wn to be implicated in MNDs, there remains a lack of clarity regarding the key functional pathways in

153 The phylogenetic analysis demonstrated the lack of clonal evolution for African strains which concl

154 acing cancer immunotherapy, which range from lack of confidence in translating pre-clinical findings

155 However, there is a lack of consensus regarding the presence, as well as the

156 failure to state conflicts of interest, and lack of consultation with families of affected children.

157 atalytic conditions demonstrate a surprising lack of correlation evident between V(on) and equivalent

158 A lack of cost-effective, reproducible models for the stud

159 few plant foods as healthy and less-healthy, lack of data on vegetable oil intake, and possibility of

160 individuals and HD patients, supporting the lack of deficit in mitochondrial protein import.

161 istency and ambiguity in instructions show a lack of definitive knowledge on best spray use technique

162 s include underrepresentation of women and a lack of detailed information on social determinants of h

163 In contrast, there is still a lack of diagnostic biomarkers of functional dystonia and

164 Considering lack of difference in BTMs between PIM/PIMP and cluster

165 these cells for almost two decades despite a lack of direct evidence.

166 onses in the early visual cortex despite the lack of direct receptive field activation.

167 Lack of dynamic plasticity is a significant limitation f

168 egative breast cancer (TNBC) is limited by a lack of effective molecular therapies targeting this dis

169 ed diagnosis and treatment of AKI due to the lack of efficient early diagnosis is an important cause

170 oms is an extraordinary challenge due to the lack of electronic or steric bias between the two positi

171 Lack of ERalpha in GHRH neurons disrupts growth in both

172 Unhealthy diet, lack of exercise, psychosocial stress, and insufficient

173 ing of cis-clustering has been hindered by a lack of experimental approaches capable of detecting and

174 dent adaptive evolution steps to address the lack of experimental methods to systematically identify

175 t such calibrations are precluded because of lack of experimental relative permeability data.

176 Unfortunately lack of expertise can lead to improper diagnosis of woun

177 nts containing Y187 were sterile, indicating lack of fertility restoration.

178 our previous model of SZ and can explain the lack of full efficacy of conventional antipsychotic medi

179 This lack of full-length genomes hampers our ability to under

180 tructural organization of neural cells and a lack of functional glia and vasculature.

181 generating antibody-based inhibitors is the lack of fundamental information relating sequences of an

182 At 1 week post-MI, lack of Gal-3 markedly attenuated F4/80+ macrophage infi

183 national attention for conservation, but the lack of genomic resources for Dalbergia hinders evolutio

184 erogeneous or undetected causal antigens and lack of gold-standard biomarkers.

185 cause of restricted insurance coverage and a lack of guidelines addressing the use of targeted panels

186 This lack of homogeneity could suggest that the deleterious e

187 ertainties in C stock estimates as well as a lack of information about depth, bulk density and carbon

188 However, there has been a lack of information about Gdf15 activity and effects in

189 This lack of institutional diversity, unless addressed, will

190 te-induced allergic airway inflammation, the lack of IRF4 expression in the DC compartment alleviates

191 he development of curative strategies is the lack of knowledge regarding mechanisms that allow HIV-in

192 Finding a lack of local connectivity, we used optogenetic circuit

193 marrow, resulting in hyporesponsiveness and lack of long-term persistence of Vi-specific IgG in seru

194 ibility remains unexplored on account of the lack of long-term prospective studies from infancy to th

195 Together with lack of markers, the need for novel markers for the dete

196 In this study, the lack of methodology to access both syn and anti diastere

197 sment of their impact has been hampered by a lack of methodology to measure the amount of, and variab

198 rtant biological and chemical relevance, the lack of methods for their production has hampered access

199 s organization has remained elusive due to a lack of methods to directly probe nanoscopic membrane fe

200 by the pathogen's slow doubling time and the lack of methods to quickly quantify the pathogen's respo

201 These failures were largely due to a lack of MMP-selective agents; accordingly, it has become

202 for industrial-scale applications, including lack of mono-selectivity, use of expensive oxidants and

203 IT logistical reasons and lack of motivation are barriers to uptake and compliance

204 ormation technology (IT) logistical reasons, lack of motivation, or competing life demands.

205 Due to lack of moving parts, the novel multi-analyte format is

206 This lack of overall increase or decline was consistent acros

207 Lack of overlap likely stems from biological rather than

208 Lack of P2X7 promoted a transcriptional signature that c

209 d long-term oral tolerance, characterized by lack of parvalbumin-specific antibody and cellular respo

210 rement on only the youngest children and the lack of power to detect small effect sizes with this rar

211 s in outcome measures and their definitions, lack of pre-specified protocols and/or trial registratio

212 Lack of precision in both neuroanatomical and clinical b

213 s might be of overall higher quality but the lack of predation pressure and resource restrictions mas

214 Taken together with the lack of progression-free survival benefit, these finding

215 nd fate of T cells in tumour immunity is the lack of quantitative information on the distribution of

216 nts being evaluated for tuberculosis (TB), a lack of rapid diagnostic tests which can fully describe

217 hanical metamaterials remain hindered by the lack of rapid-prototyping ferroelectric metamaterial str

218 rotein structure alignment/comparison due to lack of real applications associated with GPSC.

219 urs, have been largely unexplored due to the lack of real-space imaging at single particle resolution

220 these differences are unable to explain the lack of replication in Markel, 2020.

221 Here we examined the consequences due to the lack of representation by genotyping in a large number o

222 ticity, and memory in adulthood, despite the lack of requirement for neuronal survival.

223 Nevertheless, the daily workload and the lack of resources sometimes limit the advance of radiolo

224 for participants with a missing viral load, lack of retention in care in the on-site ART programme)

225 acial aluminosilicate mineral weathering and lack of retention of these species in sediments.

226 a full-pulse analysis and may suffer from a lack of sensitivity and poor reaction time.

227 annotated sgl, mainly due to the small size, lack of sequence similarity, and embedded nature of thes

228 Moreover, a lack of serine results in the initiation of biofilm form

229 erapy technologies is limited in part by the lack of small genetic switches with wide dynamic ranges

230 Lack of SMGs and mucus strands disrupted mucociliary tra

231 f N-glycans in rodent brains, but there is a lack of spatial resolution as either the tissue samples

232 omic datasets remains a challenge due to the lack of specific tools for doing so.

233 However, the lack of standardized definitions and validated reference

234 urrent pregnancy loss has been hampered by a lack of standardized definitions, the uncertainties surr

235 es the origins of stereoselectivities or the lack of stereoselectivity, and evaluates why selectivity

236 om adolescence to middle adulthood, and by a lack of substantial decline from middle to old adulthood

237 potential for aerosol spread and the current lack of sufficient countermeasures.

238 decay (NMD) degrades EJC-bound mRNA, but the lack of suitable methodology has prevented the identific

239 oV-2 infection and ameliorate disease is the lack of susceptible small animals in large numbers.

240 comings in a number of guidelines, including lack of systematic processes in formulating guidelines,

241 mmune responses is currently hampered by the lack of systems enabling quantitative and dynamic phenot

242 typically an incurable malignancy due to the lack of targetable surface targets for development of ef

243 in nanopores(1-5) have been hampered by the lack of techniques with sufficient sensitivity to discer

244 ISPR-Cas-based nucleic acid biosensing has a lack of the quantitative detection ability and typically

245 Given the current lack of third-line treatment options, this approach warr

246 The lack of tools to reliably detect RanBP9 in vivo has sign

247 Hepatology providers report lack of training to deliver PC along with no clear progn

248 Potential lack of tropospheric relevance associated with these che

249 oach to cancer therapy but is limited by the lack of tumor-homing capability of the current antiangio

250 r a primary ventral hernia, but consensus is lacking on the management in women who might subsequentl

251 -null embryoid bodies with PTEN mutants that lack only PTEN's lipid phosphatase activity or both PTEN

252 Discontinuation was due to lack or loss of efficacy in 74 patients, adverse event i

253 ermine why individuals with MRS specifically lack pancreatic endocrine cells, we micro-CT imaged a 12

254 was not yet functional, and the electrocytes lacked papillae.

255 However, most widely used clinical assays lack patient-matched control DNA and additional analysis

256 Here, we report that mice lacking Pdcd1 (Pd1-/-) demonstrated remarkable protectio

257 he catalytic domain of PDE3A in cancer cells lacking PDE3A is sufficient to confer sensitivity to DNM

258 Moreover, mice lacking PI3Kalpha and PI3Kdelta in Treg cells developed

259 Here, we report that males lacking piRNAs from a conserved mouse pachytene piRNA lo

260 ce complexity, has high proline content, and lacks predicted secondary structure.

261 laxing shelter-in-place orders worldwide, we lack quantitative evidence on how policies in one region

262 logies focus on pathogen identification that lack rapid testing of the patient immune response, imped

263 Currently, we lack reliable biomarkers to predict the development of S

264 en for Utricularia and Spirodela, which both lack root hairs and the root hair expansin clade EXPA-X.

265 Wild-type PfCRT (PfCRT3D7) lacks significant chloroquine (CQ) transport activity, b

266 regation of unrelated adults are smaller and lack specialization.

267 d undifferentiated pleomorphic sarcoma (UPS) lack specific molecular underpinnings, show high rates o

268 application of acetic acid or Lugol iodine) lack specificity and sometimes can lead to unnecessary b

269 for Clostridioides difficile infection (CDI) lack specificity or sensitivity, which has led to guidel

270 Male mice lacking sperm-specific calcineurin (PP2B), a calcium reg

271 oquinolones may be equally as effective, yet lack sufficient data.

272 in response to vibrations from hovering bees lacks supporting evidence.

273 ence data are available and predicts classes lacking tandem mass spectrometry training data.

274 Yet, charge disproportionation lacks technological relevance because it occurs only und

275 Plants possess MIF orthologs but lack the associated receptors, suggesting functional div

276 hesis, cognitively-impaired individuals will lack the cognitive ability to employ technologies.

277 Moreover, the basal SG lack the competence to respond to FGFR signaling, preven

278 ants, existing variant annotation algorithms lack the efficiency and scalability to process big genom

279 During encoding of speech sounds, SZ lacked the correlation of iHGP with task performance in

280 dation and 9,11-desaturation of GAs, but was lacking the 3-oxidation activity.

281 Here we show, by analyzing Batf3(-/-) mice lacking the CD103(+) conventional dendritic cell type 1

282 PnV-tumor was necrotic, lacking the histopathological characteristics typical of

283 ndria" with altered MAMs in brown adipocytes lacking the Sel1L-Hrd1 protein complex of ER-associated

284 lation of muropeptides with tripeptide stems lacking the terminal d-ala-d-ala and reduced peptidoglyc

285 Structures of mutant pre-ribosomes lacking the tunnel domain of uL4 reveal a misassembled N

286 , and IL-10 signaling is suboptimal in cells lacking the WDD owing to delayed endocytosis and ineffic

287 ed and archived at the MRC Harwell Institute lacks the chromosome 11 modifier but instead harbors an

288 the extracellular ligand binding domain but lacks the intracellular signaling domain.

289 Conventional DBS-fMRI, however, lacks the sensitivity needed for decoding multidimension

290 s can uniquely activate T cells, whereas DCs lacking them do not.

291 A strain lacking these three transporters was able to tolerate 10

292 Mice that lack TLR9 are deficient in both exercise-induced activat

293 on the local/window-based information while lacking to consider useful protein-level characteristics

294 rinsic pontine gliomas (DIPGs) are fatal and lack treatments.

295 Mice lacking TrkB.T1 show impaired glucose tolerance and insu

296 Recombinant ZIKV mutants that lack ubiquitination are attenuated in human cells and in

297 for most terrestrial ecosystem processes, we lack understanding of their interactive effects on ecosy

298 areas of congenitally blind individuals who lack visual imagery.

299 While mutant plants lacking xanthophylls are capable of photoautotrophic gro

300 SCs lacking YAP/TAZ, however, fail to upregulate myelin-asso