ライフサイエンスコーパス: large

1 nstants leads to times that are unphysically large.

2 en the proportion of outliers was relatively large.

3 H5N1 sequences that are only associated with large administrative areas of origin and assign them wit

4 This is because we need to face not only a large amount of data but also its non-stationary nature.

5 ich critically relies on the availability of large amounts of accurate, diverse, and representative d

6 As large amounts of biological data continue to be rapidly

7 mic sector as new forms of research based on large amounts of data will be possible, and new research

8 While endocervical epithelial cells secreted large amounts of several cytokines and chemokines, espec

9 In some cases, large amounts of specific sphingolipids must be synthesi

10 As in sensory thalamic systems, large amygdalar terminals innervated excitatory relay an

11 The large and alternatively-spliced ECRs of adhesion G prote

12 nt of energy storage devices that can endure large and complex deformations is central to emerging we

13 ts of overrepresented GO terms are often too large and contains redundant overlapping GO terms hinder

14 )) emissions from oil and gas activities are large and poorly quantified, with onshore studies showin

15 from diverse angiosperm lineages, including large and recent transfers from the Asteraceae, and also

16 However, a large and robust body of literature suitable for synthes

17 ding between the United States and Canada is large and widening, and it apparently reflects the ineff

18 preventing T2D; however, the at-risk pool is large, and a clinically meaningful metric for risk strat

19 The time-of-day effect is large, and exceeds the time difference between gold and

20 In a large animal model of vascular embolization, it is shown

21 coding RNA-based studies conducted mainly in large-animal models, including pigs, rabbits, dogs, and

22 been much more limited within the brains of large animals compared to rodents, rendering this approa

23 Most countries with large annual reductions in such mortality between 1990 a

24 they possess tightly packed shells devoid of large apertures.

25 fidence interval [CI] = 44-113%) in risk for large artery ischemic stroke, a 57% (95% CI = 29-91%) in

26 amma' fibrinogen levels on cardioembolic and large artery stroke risk.

27 s, viewed with a 10x objective lens, were as large as 4 x 5 mm(2).

28 of precision medicine approaches for diffuse large B cell lymphoma (DLBCL) is confounded by its prono

29 follicular lymphoma (FL), GC B cell-diffuse large B cell lymphoma (GCB-DLBCL), and Burkitt lymphoma

30 ity against recurrent and refractory diffuse large B cell lymphomas (DLBCL).

31 is in an activated B-cell-like (ABC) diffuse large B-cell lymphoma (DLBCL) xenograft model, but this

32 PDs offer a signal/noise ratio of ~10(6) , a large bandwidth of 543 kHz and an ultralow detection lim

33 alow gametocyte densities were quantified in large blood volumes.

34 Instead, five extant and nine extinct large bodied animals disappeared from the region at the

35 te large panels of peptides and subsequently large bodies of peptide-MHC-II interaction data are key

36 The key correlates of this contraction are large body mass, increase in air temperature, loss of na

37 Over the past three decades, a large body of literature has focused on understanding th

38 Large bottlebrush complexes formed from the polysacchari

39 ywords: Abdomen/GI, CT, Comparative Studies, Large BowelSupplemental material is available for this a

40 In large cardiovascular outcome trials in patients with dia

41 tients with classic medulloblastoma (CMB) or large-cell/anaplastic medulloblastoma (LCA).

42 c prevalence of lipodystrophy disorders in a large clinical care cohort.

43 ary intervention and its use is supported by large clinical outcome trials.

44 TCRalphabeta analyses of MAIT cells revealed large clonal expansions in older adults and tissues that

45 Here, we functionally characterize a large cluster of microRNAs (miRNAs) expressed from the m

46 to long-term maintenance of extraordinarily large CMV-specific T cell populations.

47 In a large cohort of 302 volunteers, early morning vaccinatio

48 ens which are being further evaluated with a large cohort of blinded samples from the CDC and Columbi

49 me of 231 plasma and 97 fecal samples from a large cohort of children with ASD and typically developi

50 e factors associated with survival time in a large cohort of HIV/HTLV-1-coinfected and HIV-monoinfect

51 ive deficits remains to be determined with a large cohort of participants.

52 while still providing high-quality care to a large cohort of patients with heart failure, heart trans

53 tening complication, but studies focusing on large cohorts of patients transplanted for primary immun

54 iopsoas muscle volume that can be applied to large cohorts.

55 Using data from a large, community-based integrated health care setting, w

56 where many new high-resolution structures of large complexes and membrane proteins are determined reg

57 by the U2-type or the U12-type spliceosomes, large complexes of small nuclear ribonucleoprotein parti

58 ifically, mass-transport limitations lead to large concentration gradients in the solution-phase and

59 lcium and reactive oxygen species activate a large conductance channel in the inner mitochondrial mem

60 of great benefit in clinical practice and a large cost-saving in clinical trial recruitment.

61 We illustrate MOG by case studies of large curated datasets from human cancer RNA-Seq, where

62 thium; they featured sustained activity with large current injections and a large, fast after-hyperpo

63 s completeness by comparing sequences with a large database of complete viral genomes, including 76,2

64 We compress gene expression data from three large datasets consisting of adult normal tissue, adult

65 ire sequencing samples allows for annotating large datasets on-line.

66 or have yet to demonstrate their utility in large datasets.

67 Balloon angioplasty produced a large decrease in both the noninvasive arm-to-leg blood

68 Large decreases in ICU-acquired infections occurred acro

69 enzymes are limited in their ability to make large deletions.

70 fluorescence (TADF) in spite of a relatively large DeltaE(ST) measured through phosphorimetry (0.33-0

71 onal indications for transplantation include large desmoid tumors and other intra-abdominal tumors wi

72 The above phenomena can account for the large discrepancies among the previously reported spin H

73 (Kv7.2/Kv7.3) channels and demonstrates that large disease-linked and experimentally generated C-term

74 Human cultures store memories in large distributed assemblies composed of individual brai

75 ) and its efficiency for the introduction of large DNA sequences in zygotes is low.

76 ansfer, which detects nanodomains as well as large domains.

77 ailability is difficult to quantify can have large downstream impacts on our ability to elucidate mol

78 ly subtle, but still sufficient to produce a large effect on CA-SP1 cleavage.

79 ior cingulate cortices in schizophrenia with large effect sizes (Cohen's d = 0.8-0.9), but there was

80 13.78, p = .001; Cohen's f = 0.39, medium to large effect) and duration of untreated psychosis predic

81 l fungi and bacteria are ubiquitous and have large effects on individual plant fitness.

82 may negatively impact fish growth due to its large energy expenditure, and future studies are warrant

83 se and early menarche, with risk of AAA in a large, ethnically diverse cohort of women.

84 Ruddlesden-Popper halide perovskites with a large exciton binding energy, self-assembled quantum wel

85 ated data shows that our method can identify large expansions of 41 out of 44 pathogenic repeats, inc

86 t method for surveying cell populations from large experiments or clinical samples with the depth and

87 Examining a large family of circuit models with non-identical neuron

88 G protein-coupled receptors (GPCRs) are a large family of integral membrane proteins responsible f

89 mall fast-moving population can outcompete a large fast-growing population by impeding its migration

90 all fast-growing population can outcompete a large fast-moving population by expelling it from the in

91 activity with large current injections and a large, fast after-hyperpolarization, similar to what we

92 l tracers at a volumetric rate of 14 Hz, and large field of view imaging of neurons, developing embry

93 Women with small or large for gestational age offspring are at increased ris

94 reatment had an increased risk of delivering large-for-gestational-age infants (odds ratio, 1.15; 95%

95 o be the fundus of the significantly ptotic, large gallbladder.

96 There is a large gap between the aspiration of considering sex as b

97 e community prevalence of COVID-19 is low, a large gap exists between positive predictive values of c

98 This regulation occurs in the context of large genomes condensed by histone proteins into chromat

99 lso known by the aliases GP340 and SALSA), a large glycoprotein with multiple O-glycosylation repeats

100 In a large group of adult TD patients compared to healthy con

101 Thus, viral rhodopsins 1 represent a unique, large group of light-gated channels (viral channelrhodop

102 ement initiation involves the modulations of large groups of neurons in the primary motor cortex (M1)

103 Neuregulin protein 1 (NRG1) is a large (> 60-amino-acid) natural peptide ligand for the E

104 ressed primate genes near the breakpoints of large (>100 kilobases (kb)) inversions but not smaller e

105 We describe 2 large (>5 kb) recombination events, one of which arose i

106 ctic radiofrequency ablation (SRFA) for very large (>=8 cm) primary and metastatic liver tumors with

107 Participants were employees of a large hospital in Boston, MA, who enrolled in the study

108 e issues of excessive contact resistance and large hysteresis in ambient conditions.

109 ssembles the mitotic spindle [1], is notably large in the zebrafish embryo (246.44 +/- 11.93 mum(2) i

110 Large in-plane compressive and out-of-plane tensile stra

111 isease 2019 (COVID-19) pandemic has led to a large increase in mortality in the United States and aro

112 During both NREM and REM sleep, mice showed large increases in cerebral blood volume ([HbT]) and art

113 estimates of transcript abundance levels and large increases in the number of false-positive genes an

114 Large, intact corals can help build past (century-scale)

115 jecting the probe into the lumen of small or large intestine fragments, robust phosphorescence intens

116 munities' compositions of terminal ileum and large intestine in 5 healthy individuals.

117 om spreading from the small intestine to the large intestine.

118 Large intramolecular (13)C kinetic isotope effects (KIEs

119 tion of IL-1beta inhibition for treatment of large joint osteoarthritis.

120 of the anisotropy stays the same despite the large lattice distortion.

121 itivity OFF-RGCs that selectively respond to large light decrements, (b) high-sensitivity OFF-RGCs th

122 hibits an inhibitory conformation in which a large linker domain blocks activation and substrate acce

123 ing reserve responses were consistent with a large literature, with higher coral cover, more species

124 ing principles that govern assembly of these large loci as well as for mechanisms that might contribu

125 n, so police raids and scams regularly cause large losses to marketplace participants.

126 The large majority (89%) of missense variants were functiona

127 oom-temperature dielectric permittivity with large mechanical tunability (a 90% change upon +/-0.1% s

128 of Saccharomyces cerevisiae Spf1 revealed a large, membrane-accessible substrate-binding pocket that

129 For long-running jobs or large memory needs we provide detailed guidance on high-

130 simulation tools that exist scale poorly to large modern phylogenies, which can comprise thousands o

131 building highly accurate PESs for relatively large molecular and reactive systems.

132 ons in a regioselective manner to synthesize large molecular libraries for studying structure-activit

133 lly complete but disarticulated skull of the large morphotype, including its endocast and inner ear,

134 Understanding and visualizing these large multi-dimensional datasets during acquisition and

135 new method to detect such candidate genes in large multi-omic case-control studies that measure multi

136 he 71 UGGT substrates identified were mainly large multidomain and heavily glycosylated proteins when

137 biomarker field in FTD, but the creation of large multinational cohorts is facilitating better power

138 ilated on controlled modes and enrolled in a large, multinational, epidemiological study.

139 In photosynthetic electron transport, large multiprotein complexes are connected by small diff

140 9_Trex2 system makes it possible to create a large mutant resource for S. viridis in a rapid and high

141 g pure MXene films containing highly aligned large MXene flakes.

142 ase entities, detailed long-term outcomes of large NAFLD-associated HCC cohorts are lacking.

143 atially resolve individual tens of nanometer large nanoparticles under ultrahigh vacuum (UHV) as well

144 ng, in which an excitatory synapse generated large negative extracellular signals that nonsynapticall

145 key GTPase in cancer, particularly because a large number of cancer cell lines with characteristic me

146 A large number of Cys peptides (412) were redox switched,

147 nd maintaining accurate variant databases, a large number of disease-associated variants are still hi

148 To achieve high accuracy, we performed a large number of expert-based annotations, 72,722 in tota

149 traits was Fisher's infinitesimal model of a large number of genetic variants, each with very small e

150 A large number of newly synthesized membrane proteins in t

151 Considering the large number of physical and chemical factors involved i

152 In addition, a large number of preclinical studies have demonstrated th

153 he lack of representation by genotyping in a large number of self-reported Native Hawaiians (N = 3693

154 cept that has been successfully applied to a large number of target structures, but requires excess q

155 as a single step gradualistic process with a large number of transition cells between the basal and s

156 rom almost the entire blood volume, but such large numbers and concentrations of cells are incompatib

157 ing are complex and compositional because of large numbers of detectable taxa, and because microbiota

158 rming efficient reagent exchange on chip for large numbers of embryos remains a bottleneck.

159 oan transcription factors typically regulate large numbers of genes.

160 ged with pressure rise while an increase for large oligonucleotides was observed, indicating their al

161 ductivity, fast response time, and extremely large on/off ratio upon visible-light irradiation.

162 al pathology and transcriptome analysis on a large ovarian tumour cohort and develop a machine learni

163 Furthermore, we fingerprinted a large panel of 4143 lines for the 2NS translocation that

164 The ability to generate large panels of peptides and subsequently large bodies o

165 sity is undergoing rapid declines, driven in large part by changes to land use and climate.

166 he commuting microenvironment accounts for a large part of students' diurnal exposure to air pollutio

167 ity of Qbeta viral-like particles relies, in large part, on their ability to effectively recruit T ce

168 In this large pediatric cohort of patients with BAV, valve morph

169 the accuracy of local ancestry inference in large pedigrees by: (1) using an existing algorithm to i

170 reductions in sulfur-dioxide emissions from large point sources and nitrates and EC emissions from m

171 flowers with short styles, long anthers, and large pollen grains.

172 ein Gag selects full-length HIV-1 RNA from a large pool of mRNAs as virion genome during virus assemb

173 eous measurement of thousands of proteins in large population studies, exposing the depth and complex

174 In this large, population-based, family database, the risk of PC

175 ity, heart failure (HF) is responsible for a large portion of healthcare and disability costs worldwi

176 ntil antibiotics, and failure to control for large potential confounders including patients' presenti

177 In fact, a large proportion of islet-infiltrating B lymphocytes in

178 hen poorly controlled, COVID-19 can infect a large proportion of the population, causing high mortali

179 With a large proportion of the world's population living in are

180 RNA binding proteins (RBPs) are a large protein family that plays important roles at almos

181 Folding of individual domains in large proteins during translation helps to avoid otherwi

182 proximal SPs 2.6; 95% CI, 1.7-3.9 and HR for large proximal SPs 8.0; 95% CI, 3.6-16.1).

183 the Balkans have a common feature of eating large quantities of fermented foods.

184 ter observational study using data from four large randomized controlled trials investigating differe

185 C-N adducts at room temperature as well as a large range of previously inaccessible Ullmann-Goldberg

186 Solvolytic rate studies show no large rate enhancements due to the t-butyl group in 7.

187 re full length, intact OR genes, and found a large ratio of partial and pseudogenes to intact OR gene

188 There was no evidence of large reductions in SFA, but we are unable to exclude mo

189 This benefit can extend to a large region because two thirds of patients treated at K

190 A large region of fission yeast DNA inserted into a mouse

191 ng ECGs collected over a 34-year period in a large regional health system, we trained a DNN with 1,16

192 ug exposures with statistically significant, large relative risks indicating that cases were less fre

193 a random-effects within-between model to two large representative datasets of individual web browsing

194 plications, due to the shorter retention and large resistance changes.

195 Network applications is reported, given the large retentions and symmetry, and opportunity for the l

196 This large retrospective cohort study helps characterize the

197 r (RsfS) that binds to uL14 protein onto the large ribosomal subunit and prevents its association wit

198 d by eIF5B in concert with components of the large ribosomal subunit.

199 bosomal protein genes of either the small or large ribosomal subunit.

200 Here, testing a large sample (N = 72) using an established paradigm and

201 In a large sample of community-dwelling individuals, acute ex

202 The findings based on MR analysis in a large sample of European ancestry do not support a causa

203 We observed a low HCV prevalence in this large sample of MSM despite a high prevalence of known r

204 Although T cell commitment is accompanied by large scale epigenetic changes, we observed that the maj

205 ntal and taxonomical structure, we show that large scale patterns in the EMP can be reproduced by con

206 ical role, because they can be deployed at a large scale to monitor the individuals' drug transcourse

207 ay make it possible to monitor well-being at large scale.

208 S-turbo, purpose-built software designed for large-scale analyses of splicing, and identified 13,149

209 odological differences present challenges to large-scale analysis across datasets.

210 omics, but cost and labor requirements limit large-scale application.

211 The results pave the way for practical large-scale applications of high-performance SDRC for hu

212 rm-integrated algorithms could be applied to large-scale cancer studies, such as The Cancer Genome At

213 tterns despite noisy morphogen signaling and large-scale cellular rearrangements during morphogenesis

214 properties of the cornea, the absence of any large-scale changes following treatment confirms the pot

215 has been widely implicated as the source of large-scale changes in the subpolar marine environment.

216 the viscosity to zero, [Formula: see text], large-scale collective motion emerges in the quiescent s

217 tation detection approach that is useful for large-scale comparative protein function studies.

218 correlations between fluorophore motions and large-scale conformational changes between LIV-BPSS doma

219 use residual uncorrected stratification from large-scale consortium studies was considered responsibl

220 iconformist bias to explain the evolution of large-scale cooperation, and subsequent research has ext

221 A pressing question is to understand how large-scale cross-linking mass spectrometry (XL-MS) can

222 Here, we present a large-scale dataset of 849 3D reconstructions of the bas

223 by visual analysis but could be learned from large-scale datasets.

224 However, high performance, large-scale EGT arrays, and EGT application for spatiote

225 Large-scale energy storage is becoming increasingly crit

226 In this context, large-scale forcing of ISM rainfall variability with mul

227 sitivity of tropical soil carbon turnover to large-scale hydroclimate variability remains poorly unde

228 al travel restrictions and by the province's large-scale intensive surveillance and intervention meas

229 TaNT clearly provides a safe strategy for large-scale ivermectin treatment and overcomes a major o

230 ere, we introduce a method named EXoO-Tn for large-scale mapping of Tn-glycosylated proteins and glyc

231 lpha oscillations with higher frequencies in large-scale networks connecting anterior and posterior b

232 n omics screening to populations enrolled in large-scale observational and clinical trials.

233 shift from small-scale biological control to large-scale oceanographic control of these communities.

234 experimental studies of virus evolution and large-scale phylodynamic analyses.

235 dy aimed to validate its prognostic value in large-scale population and explore the impact of menopau

236 investigate transmission chains and explore large-scale population dynamics, such as the spread of a

237 unt for ~50% of the projected total cost for large-scale production.

238 for localized prostate cancer by integrating large-scale prostate cancer genomes and the prostate-spe

239 k also constitutes an important step towards large-scale quantum dot simulators of correlated electro

240 , SAE and high-dose radiation exposure using large-scale registry data.

241 In an era of large-scale science-related challenges and rapid advance

242 implify frontline diagnostics and facilitate large-scale serological surveillance and postvaccination

243 s can also be applied to other domains where large-scale statistical analyses over encrypted data are

244 of the UbiFast method makes it suitable for large-scale studies in primary tissue samples.

245 ZBTB18, TCF12, SPEN, and LEO1) based on this large-scale targeted sequencing effort.

246 vironmental productivity patterns, including large-scale variability in pathogens, vectors and associ

247 ees, associated with the annual operation of large-scale wood pellet mills.

248 Our study presents the first large-scale, exome-wide analysis of rare variants in AMD

249 o e-cigarette use have been reported, but no large series has been described.

250 algorithms to sea level pressure data from a large set of climate model simulations and, as a proxy f

251 ovel information regarding the activity of a large set of progestins on human and zebrafish PR and hi

252 tility of this transformation by aminating a large set of terpenoids in high yield and regioselectivi

253 hort UV absorption edge, below 190 nm, and a large SHG response, 2.8xKDP.

254 ytochrome P450 1A genes were associated with large shifts in allele frequencies between catchments an

255 e activity of VGLUTs can be coordinated with large shifts in proton and chloride concentrations durin

256 l changes in the activity of PTP1B can cause large shifts in the phosphorylation states of its regula

257 al for scalability of real applications with large-size problems.

258 ess the inverse folding problem, exploring a large space of sequences and selecting ones predicted to

259 such as particle deposition in the lung, the large spatial gradients of chemical mixing state may sig

260 rambadi, groundwater composition displayed a large spatial variability with Cl contents spanning 3 or

261 orbital overlap results in strongly coupled, large-spin ground states in the [Ni(4)(NP(t)Bu(3))(4)](+

262 potential near filling factor one reveals a large spontaneous magnetization, further substantiating

263 the protein environment and accounts for the large Stokes shift of GFP in response to near UV excitat

264 We initially screened a library with a large structural variety of lipidoids ex vivo and identi

265 s in the conserved N terminus of the Rubisco large subunit.

266 ing infrastructure is pervasive and occupies large swaths of land in cities.

267 en for that system to collapse, meaning that large systems tend to shift more slowly than small syste

268 egration, persistent overexpression of viral large T antigen (TAg), and malignancy, yet little is kno

269 ful nanomachine built by several copies of a large (TerL) and a small (TerS) terminase subunit.

270 vely identified in women at two hospitals (a large tertiary care academic hospital and a National Com

271 tly employ definitions of small, medium, and large that were proposed by Jacob Cohen.

272 When the number of studies K is large, the 3K - 1 possible differential expression patte

273 reality software package designed to render large three-dimensional single-molecule localization mic

274 at the Protein Data Bank is now sufficiently large to enable proteins to be designed by using only ex

275 ienced low human impact and still constitute large tracts of contiguous forest interior.

276 ereby enabling the acquisition of reasonably large training datasets that hold the key for label-free

277 lmost 900,000 scientific abstracts without a large training set of labeled annotations.

278 ability of complex VSV recombinants carrying large transgenes.IMPORTANCE Vesicular stomatitis virus (

279 explored S(N)2 pathway for the reaction with large transition state stabilization at relatively low O

280 This catalyst exhibits an extremely large turnover frequency (TOF) up to 12500 h(-1) at -0.9

281 onal cases), but only under RCP8.5, and with large uncertainty around this projected increase.

282 y on a multispanning protein incorporated in large unilamellar liposomes showing a stable lipid asymm

283 Anion transport experiments in POPC-based large unilamellar vesicles show that these main-group ca

284 ry calculations and symmetry analysis of the large unit cell crystalline approximant of the quasicrys

285 term agricultural field studies conducted by large United States bioenergy research programs.

286 d to targeted sequencing data derived from a large unselected population-based patient cohort with fu

287 ffect mechanical gating and may be linked to large variability in tension sensitivity among these mem

288 A large variation in the proportion of shared zOTUs was ob

289 the discrimination performance obtained for large variations in size was no lower than that obtained

290 he potential for profound adverse events and large variations in survival outcome.

291 ations of a stimulus-occurs when observing a large variety of ambiguous stimulus configurations.

292 low (236)U/(238)U isotope ratios can offer a large variety of geochemical applications in particular

293 patients with acute ischaemic stroke due to large vessel occlusion within a 12 h treatment window.

294 g of the structure-function relationships of large viruses and should aid in ASFV vaccine development

295 Imaging neurons and neural circuits over large volumes at high speed and subcellular resolution i

296 nd noninvasively, it is readily available in large volumes, it is typically free from protein contami

297 vessel dilation and constriction dynamics in large volumes.

298 t of computational resources required by the large water box of standard all-atom steered molecular d

299 y and steady-state cellular abundance with a large, well-curated clinical cohort of PTEN-variant carr

300 complete weeks' gestation, a small GS and a large YS reliably predicted pregnancy loss.